Click here to switch to the map view.

The map label for this gene is dapB

Identifier: 157825329

GI number: 157825329

Start: 204120

End: 204857

Strand: Reverse

Name: dapB

Synonym: A1C_01055

Alternate gene names: 157825329

Gene position: 204857-204120 (Counterclockwise)

Preceding gene: 157825330

Following gene: 157825328

Centisome position: 16.64

GC content: 30.49

Gene sequence:

>738_bases
ATGATAAATATAGGTCTTAGCGGTTCTACCGGTAAAATGGGAAAAACTATTCTAGCGAGAATAGATAAATTTAAAGATTG
CAAAATTTCAGCAAAATTTAATAGTACTGATGATTTAGATGATTTAAATAATTTTTGTAAAAATTCTGATGTAATCATCG
ATTTTTCCACTCCTGAAATATTAGAAAAATTAATTAATTATGCATTAAAACATAATACAAAATTAGTAATCGGAACCACA
GGACTTCAGCCTAAACATTTTAAGCTTTTAGAAAAAGCAGCTAAAACTTTACCTATTCTATATTCTGCAAATATGAGTAC
CGGGGCTAATTTGCTCAGCTATCTAGCAAAAAAGGCAACAAAAATACTAGATGATTACGATATTGAAATTCTAGAAACCC
ATCACCGTAATAAAAAAGATTCACCCTCAGGAACTGCTATTATGCTTGCTGAAACGATTGCAAGAGAAAAAGGATTAAAT
ATAGTATTTAATCGTGGTAACAGACCAAGAAGCGAAAAAGAAATAGGTATTTCCTCACTTCGTGGTGGAAATGTTCACAG
TATACACGAAATATCTTTACTAGGTGACGATGAAATAATCACTTTAAAACACGAAGCTCTGAATAAAAATTCTTTTGTCA
TTGGTGCAATTAAATCCGCTATTTGGCTACAAGATAAATCACCAGCTTTATATTCAATGCAAGATATTTATAATTATAGC
TTGCAAAAACAGCTCTAA

Upstream 100 bases:

>100_bases
TGAAGTAATAAATACTACTATTAAAAATGACTTAAAGCCTCTATTATATTTTCATAAATTGTATGCTCGTTGCATTTGTT
AAAAATATATTATTACCAAT

Downstream 100 bases:

>100_bases
CAGAGTATATTTTATTATGTAAATAACATAATCCTAAGGTTACTTATGATCGATTATACAAAAACTTTAACTGCTACTTC
AAAGAATAAAACTTTTGATG

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MINIGLSGSTGKMGKTILARIDKFKDCKISAKFNSTDDLDDLNNFCKNSDVIIDFSTPEILEKLINYALKHNTKLVIGTT
GLQPKHFKLLEKAAKTLPILYSANMSTGANLLSYLAKKATKILDDYDIEILETHHRNKKDSPSGTAIMLAETIAREKGLN
IVFNRGNRPRSEKEIGISSLRGGNVHSIHEISLLGDDEIITLKHEALNKNSFVIGAIKSAIWLQDKSPALYSMQDIYNYS
LQKQL

Sequences:

>Translated_245_residues
MINIGLSGSTGKMGKTILARIDKFKDCKISAKFNSTDDLDDLNNFCKNSDVIIDFSTPEILEKLINYALKHNTKLVIGTT
GLQPKHFKLLEKAAKTLPILYSANMSTGANLLSYLAKKATKILDDYDIEILETHHRNKKDSPSGTAIMLAETIAREKGLN
IVFNRGNRPRSEKEIGISSLRGGNVHSIHEISLLGDDEIITLKHEALNKNSFVIGAIKSAIWLQDKSPALYSMQDIYNYS
LQKQL
>Mature_245_residues
MINIGLSGSTGKMGKTILARIDKFKDCKISAKFNSTDDLDDLNNFCKNSDVIIDFSTPEILEKLINYALKHNTKLVIGTT
GLQPKHFKLLEKAAKTLPILYSANMSTGANLLSYLAKKATKILDDYDIEILETHHRNKKDSPSGTAIMLAETIAREKGLN
IVFNRGNRPRSEKEIGISSLRGGNVHSIHEISLLGDDEIITLKHEALNKNSFVIGAIKSAIWLQDKSPALYSMQDIYNYS
LQKQL

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=264, Percent_Identity=29.9242424242424, Blast_Score=122, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_RICAH (A8GMB6)

Other databases:

- EMBL:   CP000847
- RefSeq:   YP_001493049.1
- ProteinModelPortal:   A8GMB6
- SMR:   A8GMB6
- STRING:   A8GMB6
- GeneID:   5645720
- GenomeReviews:   CP000847_GR
- KEGG:   rak:A1C_01055
- NMPDR:   fig|293614.3.peg.199
- eggNOG:   COG0289
- HOGENOM:   HBG594002
- OMA:   TERPGHD
- ProtClustDB:   PRK00048
- BioCyc:   RAKA293614:A1C_01055-MONOMER
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 27249; Mature: 27249

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINIGLSGSTGKMGKTILARIDKFKDCKISAKFNSTDDLDDLNNFCKNSDVIIDFSTPEI
CEEECCCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHCCCCEEEECCCHHH
LEKLINYALKHNTKLVIGTTGLQPKHFKLLEKAAKTLPILYSANMSTGANLLSYLAKKAT
HHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHH
KILDDYDIEILETHHRNKKDSPSGTAIMLAETIAREKGLNIVFNRGNRPRSEKEIGISSL
HHHCCCCCEEEEHHCCCCCCCCCCCEEEHHHHHHHHCCCEEEEECCCCCCCHHHCCHHHC
RGGNVHSIHEISLLGDDEIITLKHEALNKNSFVIGAIKSAIWLQDKSPALYSMQDIYNYS
CCCCCCEEEEEEEECCCCEEEEEHHHCCCCCEEEEEEHHEEEECCCCCCHHHHHHHHHHH
LQKQL
HHCCC
>Mature Secondary Structure
MINIGLSGSTGKMGKTILARIDKFKDCKISAKFNSTDDLDDLNNFCKNSDVIIDFSTPEI
CEEECCCCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHCCCCEEEECCCHHH
LEKLINYALKHNTKLVIGTTGLQPKHFKLLEKAAKTLPILYSANMSTGANLLSYLAKKAT
HHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHH
KILDDYDIEILETHHRNKKDSPSGTAIMLAETIAREKGLNIVFNRGNRPRSEKEIGISSL
HHHCCCCCEEEEHHCCCCCCCCCCCEEEHHHHHHHHCCCEEEEECCCCCCCHHHCCHHHC
RGGNVHSIHEISLLGDDEIITLKHEALNKNSFVIGAIKSAIWLQDKSPALYSMQDIYNYS
CCCCCCEEEEEEEECCCCEEEEEHHHCCCCCEEEEEEHHEEEECCCCCCHHHHHHHHHHH
LQKQL
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA