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The map label for this gene is gpsA [H]

Identifier: 157373047

GI number: 157373047

Start: 5333462

End: 5334481

Strand: Reverse

Name: gpsA [H]

Synonym: Spro_4815

Alternate gene names: 157373047

Gene position: 5334481-5333462 (Counterclockwise)

Preceding gene: 157373048

Following gene: 157373046

Centisome position: 97.9

GC content: 58.82

Gene sequence:

>1020_bases
ATGAACACCGTCAATGCTTCAATGACTGTAATCGGTGCCGGCTCGTACGGCACCGCATTAGCTATTACGCTGGCGCGTAA
CGGCCACTCCGTGGTGCTGTGGGGCCATAACCCCGAGCAAATTCAAAAGATGCAGCGCGATCGCTGCAATCAGGCATTTC
TTCCCGATGTCGCTTTCCCCGATACGCTGTTGCTCGAAGCCGATCTGGCGCGCGCGCTGGCTGCCAGCCGCGATGTACTG
GTAGTAGTGCCAAGCCACGTGTTCGGTGACGTGCTGCGCCAGTTGAAACCGCATCTGCGTCCGGATGCCCGCATTGTGTG
GGCCACCAAAGGGCTGGAAGCGGAAACCGGCAGGCTGTTGCAGGACGTGGCGCGCGAAGCGCTGGGCGAGGCTATTCCGC
TGGCAGTGGTCTCAGGGCCGACGTTTGCCAAAGAGCTGGCCGCCGGGCTGCCGACCGCGATTGCGCTGGCTTCTACCGAT
GCACAGTTCGCCGAAGATCTGCAGCAGTTGCTGCACTGCGGCAAAAGTTTCCGCGTGTACAGCAACCCCGATTTTATCGG
CGTTCAACTGGGCGGGGCGGTGAAGAACGTGATTGCCATCGGTGCCGGGATGTCAGACGGTATCGGGTTTGGTGCCAATG
CGCGAACGGCACTGATTACCCGTGGCCTGACGGAAATGACCCGTCTTGGCTCTGCGTTGGGGGCTGACCCATCGACCTTT
ATGGGCATGGCCGGGTTGGGCGATCTGGTGTTAACCTGCACCGATAATCAATCGCGCAACCGCCGTTTCGGTATTATGCT
GGGACAGGGTAAAGGCGTGCAGGAAGCGCAGGACAGCATCGGTCAGGTGGTCGAAGGCTATCGCAATACCAAAGAGGTAT
TGGCACTGGCGCAACGCTACGGCGTGGAAATGCCGATTACCGAACAGATTTATCAGGTGTTGTATTGCCATAAAAATGCC
CGGGAAGCTGCGCTGAGCCTGCTGGGGCGTACCAGAAAAGACGAAAAGCACAGCGCATAA

Upstream 100 bases:

>100_bases
CGCAGCTGAATCTGGCACCGGTTAACTTTGACGCGCTGTTCATGAACTATCTGCAGCAGCAGTCAGAAGGCGAAGGTGCC
GCACCACATCAGGATGCCTG

Downstream 100 bases:

>100_bases
CCTATAAAACTGATATGCGGGGCGGCATGCTGACCCGGCAATTGAATTGGGCTGCCTGACTGCGATGCGGTGAGGCAGCC
TGTTTTGCAAGGCGGAGAGG

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase [H]

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MNTVNASMTVIGAGSYGTALAITLARNGHSVVLWGHNPEQIQKMQRDRCNQAFLPDVAFPDTLLLEADLARALAASRDVL
VVVPSHVFGDVLRQLKPHLRPDARIVWATKGLEAETGRLLQDVAREALGEAIPLAVVSGPTFAKELAAGLPTAIALASTD
AQFAEDLQQLLHCGKSFRVYSNPDFIGVQLGGAVKNVIAIGAGMSDGIGFGANARTALITRGLTEMTRLGSALGADPSTF
MGMAGLGDLVLTCTDNQSRNRRFGIMLGQGKGVQEAQDSIGQVVEGYRNTKEVLALAQRYGVEMPITEQIYQVLYCHKNA
REAALSLLGRTRKDEKHSA

Sequences:

>Translated_339_residues
MNTVNASMTVIGAGSYGTALAITLARNGHSVVLWGHNPEQIQKMQRDRCNQAFLPDVAFPDTLLLEADLARALAASRDVL
VVVPSHVFGDVLRQLKPHLRPDARIVWATKGLEAETGRLLQDVAREALGEAIPLAVVSGPTFAKELAAGLPTAIALASTD
AQFAEDLQQLLHCGKSFRVYSNPDFIGVQLGGAVKNVIAIGAGMSDGIGFGANARTALITRGLTEMTRLGSALGADPSTF
MGMAGLGDLVLTCTDNQSRNRRFGIMLGQGKGVQEAQDSIGQVVEGYRNTKEVLALAQRYGVEMPITEQIYQVLYCHKNA
REAALSLLGRTRKDEKHSA
>Mature_339_residues
MNTVNASMTVIGAGSYGTALAITLARNGHSVVLWGHNPEQIQKMQRDRCNQAFLPDVAFPDTLLLEADLARALAASRDVL
VVVPSHVFGDVLRQLKPHLRPDARIVWATKGLEAETGRLLQDVAREALGEAIPLAVVSGPTFAKELAAGLPTAIALASTD
AQFAEDLQQLLHCGKSFRVYSNPDFIGVQLGGAVKNVIAIGAGMSDGIGFGANARTALITRGLTEMTRLGSALGADPSTF
MGMAGLGDLVLTCTDNQSRNRRFGIMLGQGKGVQEAQDSIGQVVEGYRNTKEVLALAQRYGVEMPITEQIYQVLYCHKNA
REAALSLLGRTRKDEKHSA

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI33695088, Length=333, Percent_Identity=28.2282282282282, Blast_Score=125, Evalue=5e-29,
Organism=Homo sapiens, GI24307999, Length=340, Percent_Identity=25.5882352941176, Blast_Score=108, Evalue=9e-24,
Organism=Escherichia coli, GI1790037, Length=338, Percent_Identity=85.7988165680473, Blast_Score=600, Evalue=1e-173,
Organism=Caenorhabditis elegans, GI32564399, Length=330, Percent_Identity=26.3636363636364, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI193210136, Length=339, Percent_Identity=25.3687315634218, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI32564403, Length=339, Percent_Identity=25.3687315634218, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17507425, Length=357, Percent_Identity=23.249299719888, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI193210134, Length=204, Percent_Identity=28.921568627451, Blast_Score=76, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6324513, Length=343, Percent_Identity=27.1137026239067, Blast_Score=112, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6320181, Length=341, Percent_Identity=28.1524926686217, Blast_Score=109, Evalue=7e-25,
Organism=Drosophila melanogaster, GI17136204, Length=330, Percent_Identity=27.2727272727273, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI17136202, Length=330, Percent_Identity=27.2727272727273, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI17136200, Length=330, Percent_Identity=27.2727272727273, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI22026922, Length=331, Percent_Identity=22.9607250755287, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI45551945, Length=241, Percent_Identity=29.4605809128631, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI281362270, Length=241, Percent_Identity=29.4605809128631, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24648969, Length=184, Percent_Identity=31.5217391304348, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040 [H]

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N [H]

EC number: =1.1.1.94 [H]

Molecular weight: Translated: 36204; Mature: 36204

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: PS00957 NAD_G3PDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTVNASMTVIGAGSYGTALAITLARNGHSVVLWGHNPEQIQKMQRDRCNQAFLPDVAFP
CCCCCCEEEEEECCCCCCEEEEEEECCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCC
DTLLLEADLARALAASRDVLVVVPSHVFGDVLRQLKPHLRPDARIVWATKGLEAETGRLL
CHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHH
QDVAREALGEAIPLAVVSGPTFAKELAAGLPTAIALASTDAQFAEDLQQLLHCGKSFRVY
HHHHHHHHCCCCCEEEECCCHHHHHHHHCCCHHEEEECCCHHHHHHHHHHHHCCCCEEEE
SNPDFIGVQLGGAVKNVIAIGAGMSDGIGFGANARTALITRGLTEMTRLGSALGADPSTF
CCCCEEEEEECHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHH
MGMAGLGDLVLTCTDNQSRNRRFGIMLGQGKGVQEAQDSIGQVVEGYRNTKEVLALAQRY
HHHCCCCCEEEEECCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHH
GVEMPITEQIYQVLYCHKNAREAALSLLGRTRKDEKHSA
CCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MNTVNASMTVIGAGSYGTALAITLARNGHSVVLWGHNPEQIQKMQRDRCNQAFLPDVAFP
CCCCCCEEEEEECCCCCCEEEEEEECCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCC
DTLLLEADLARALAASRDVLVVVPSHVFGDVLRQLKPHLRPDARIVWATKGLEAETGRLL
CHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHCCCCCCEEEEEECCCCHHHHHHH
QDVAREALGEAIPLAVVSGPTFAKELAAGLPTAIALASTDAQFAEDLQQLLHCGKSFRVY
HHHHHHHHCCCCCEEEECCCHHHHHHHHCCCHHEEEECCCHHHHHHHHHHHHCCCCEEEE
SNPDFIGVQLGGAVKNVIAIGAGMSDGIGFGANARTALITRGLTEMTRLGSALGADPSTF
CCCCEEEEEECHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHH
MGMAGLGDLVLTCTDNQSRNRRFGIMLGQGKGVQEAQDSIGQVVEGYRNTKEVLALAQRY
HHHCCCCCEEEEECCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHH
GVEMPITEQIYQVLYCHKNAREAALSLLGRTRKDEKHSA
CCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12486043 [H]