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The map label for this gene is hpmA [H]

Identifier: 157372961

GI number: 157372961

Start: 5225349

End: 5226635

Strand: Direct

Name: hpmA [H]

Synonym: Spro_4729

Alternate gene names: 157372961

Gene position: 5225349-5226635 (Clockwise)

Preceding gene: 157372958

Following gene: 157372962

Centisome position: 95.9

GC content: 50.58

Gene sequence:

>1287_bases
ATGAAAAAGGTATTACCAAGGAAAATATCCTGCCTTTCGGCCATGATAATGTTTTGCCTCAGTGGCGGAGCCGCCTTTGC
TGACGCCTCCATTGTGCCGGTTGGCGGCAACGTTAACCTCGCTGCCAATAACGTGCCGGTAGTGAATATCAATCAGCCGG
GCCAGGATGGCGTATCACATAACCAATACAGCCAGTTTGATGTAGGTAGCCAGGGCGCGGTATTGAACAATGCGCAAGGC
AGCGCGCAAAGCCAACTGGCCGGTGCCATCACCGCCAACCCCAACCTGAGCGCAGGTGCCGCGAAGGTGATTCTTAATGA
AATCAATTCCAGCGACAAAACGCTGCTGAATGGGATGATCGAAGTCGCCGGCCAGAAGGCGGACGTTATCGTCGCCAACC
GTTCCGGCATTACCTGTAACGGTTGCGGATTTATCAATACCGGTACCGGGGTACTGACCACCGGTGAACTGCAGTTCAAA
GACAAACAGTTCACCGGCTATAGCGTTACCGGCGGCACGGTAGCATTCGAAGGCAAGGGGCTGCAGAAAGGTGATGTGGA
CTACACCGCCGTGATTGCCCGCGCTGAGAATATCAATGCCGCGGTGCAAGCCAAGAGCCTGCTGGTGTTGGCGGGCAAGA
AAACCGTCACCGCAGATCTGACTCGTTACATAAACCTGGAAAACAAAGAAAAATCACCAGAAGTGTTGGTAGATGTCTCC
CAGCTCGGTGGTATGTATGCAGGAAAAATCATCTTAATCGCCAATGAAAATGGTGTGGGGGTTAATGACAGTACACCCGT
CAGCCTTAGAAATAACGGCGAATTAGTGACTGATGGCGGTGATATGTTGTTGTCTGCTACGTCTCTTTCAAACGCGGGTA
AAATCGCTGCTGGCGGCAATGCAAACCTGGCAACCACCGTGCTGTCGAACCAAGGGGATATCACGGCCAATAACGCACTT
AATATCAGCGCCACCTCTTTCAGCAACGCTAAAGACATCAGCGCAAAAAATAATATTGATATTAAGTCAACCACTACGTC
TAACAATGGGACAATAGTCTCTCAGCAAGGAGGGGTGACCGTATCGGATACGACCTTCTCCAACAACGGCACTATTCGGG
CAAAAAATAACATTTCTCATAAAGGAACGTTATTTAGCAATAACGGTACCCTGACCTCAACCCAAGGTTCAGTGTTCAAC
AACGGCAGAGACATTAATTACAAGCCTCCTGTCGTCACCCCACCGACAAACTCATGGTGGTCATCCTGGTGGTCCCGTAG
CTGGTAA

Upstream 100 bases:

>100_bases
ATTTATTGGCACCACTTAATTTAGGCGTACAGGCGCACAGCTGAAACCTGGTGAATTATCTAAGCAGTATTATAAAGCCC
TTATATCTATGGAGTAATAA

Downstream 100 bases:

>100_bases
TATTATTCCTCCGCCGCTCGGCGGAGGTTTTACCCTGACGTAAAAAATTAATATGAAAAAAAATATCCTATTACTGCTGA
GTCTATTGCAAGCAGAGGGC

Product: filamentous hemagglutinin outer membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 428

Protein sequence:

>428_residues
MKKVLPRKISCLSAMIMFCLSGGAAFADASIVPVGGNVNLAANNVPVVNINQPGQDGVSHNQYSQFDVGSQGAVLNNAQG
SAQSQLAGAITANPNLSAGAAKVILNEINSSDKTLLNGMIEVAGQKADVIVANRSGITCNGCGFINTGTGVLTTGELQFK
DKQFTGYSVTGGTVAFEGKGLQKGDVDYTAVIARAENINAAVQAKSLLVLAGKKTVTADLTRYINLENKEKSPEVLVDVS
QLGGMYAGKIILIANENGVGVNDSTPVSLRNNGELVTDGGDMLLSATSLSNAGKIAAGGNANLATTVLSNQGDITANNAL
NISATSFSNAKDISAKNNIDIKSTTTSNNGTIVSQQGGVTVSDTTFSNNGTIRAKNNISHKGTLFSNNGTLTSTQGSVFN
NGRDINYKPPVVTPPTNSWWSSWWSRSW

Sequences:

>Translated_428_residues
MKKVLPRKISCLSAMIMFCLSGGAAFADASIVPVGGNVNLAANNVPVVNINQPGQDGVSHNQYSQFDVGSQGAVLNNAQG
SAQSQLAGAITANPNLSAGAAKVILNEINSSDKTLLNGMIEVAGQKADVIVANRSGITCNGCGFINTGTGVLTTGELQFK
DKQFTGYSVTGGTVAFEGKGLQKGDVDYTAVIARAENINAAVQAKSLLVLAGKKTVTADLTRYINLENKEKSPEVLVDVS
QLGGMYAGKIILIANENGVGVNDSTPVSLRNNGELVTDGGDMLLSATSLSNAGKIAAGGNANLATTVLSNQGDITANNAL
NISATSFSNAKDISAKNNIDIKSTTTSNNGTIVSQQGGVTVSDTTFSNNGTIRAKNNISHKGTLFSNNGTLTSTQGSVFN
NGRDINYKPPVVTPPTNSWWSSWWSRSW
>Mature_428_residues
MKKVLPRKISCLSAMIMFCLSGGAAFADASIVPVGGNVNLAANNVPVVNINQPGQDGVSHNQYSQFDVGSQGAVLNNAQG
SAQSQLAGAITANPNLSAGAAKVILNEINSSDKTLLNGMIEVAGQKADVIVANRSGITCNGCGFINTGTGVLTTGELQFK
DKQFTGYSVTGGTVAFEGKGLQKGDVDYTAVIARAENINAAVQAKSLLVLAGKKTVTADLTRYINLENKEKSPEVLVDVS
QLGGMYAGKIILIANENGVGVNDSTPVSLRNNGELVTDGGDMLLSATSLSNAGKIAAGGNANLATTVLSNQGDITANNAL
NISATSFSNAKDISAKNNIDIKSTTTSNNGTIVSQQGGVTVSDTTFSNNGTIRAKNNISHKGTLFSNNGTLTSTQGSVFN
NGRDINYKPPVVTPPTNSWWSSWWSRSW

Specific function: Cell-bound hemolysin, which releases heme-iron from erythrocytes by interaction with the erythrocyte membrane. HpmA requires hpmB function [H]

COG id: COG3210

COG function: function code U; Large exoproteins involved in heme utilization or adhesion

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008638
- InterPro:   IPR012334
- InterPro:   IPR011050
- InterPro:   IPR011102 [H]

Pfam domain/function: PF05860 Haemagg_act [H]

EC number: NA

Molecular weight: Translated: 44284; Mature: 44284

Theoretical pI: Translated: 8.59; Mature: 8.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVLPRKISCLSAMIMFCLSGGAAFADASIVPVGGNVNLAANNVPVVNINQPGQDGVSH
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCEEEEECCEEEEECCCCCCCCCCC
NQYSQFDVGSQGAVLNNAQGSAQSQLAGAITANPNLSAGAAKVILNEINSSDKTLLNGMI
CCCCCCCCCCCCCEEECCCCCCHHHHEEEEECCCCCCCCHHHHHHHHCCCCHHHHHHHHH
EVAGQKADVIVANRSGITCNGCGFINTGTGVLTTGELQFKDKQFTGYSVTGGTVAFEGKG
HHCCCCEEEEEECCCCCEECCCCEEECCCCEEEECEEEEECCEECCEEECCCEEEEECCC
LQKGDVDYTAVIARAENINAAVQAKSLLVLAGKKTVTADLTRYINLENKEKSPEVLVDVS
CCCCCCCEEEEEEECCCCCEEEEEEEEEEEECCCEEEEEEEEEEECCCCCCCCCEEEEHH
QLGGMYAGKIILIANENGVGVNDSTPVSLRNNGELVTDGGDMLLSATSLSNAGKIAAGGN
HHCCEEECEEEEEECCCCCCCCCCCCEEECCCCCEEECCCCEEEEEECCCCCCEEEECCC
ANLATTVLSNQGDITANNALNISATSFSNAKDISAKNNIDIKSTTTSNNGTIVSQQGGVT
CCEEEEEECCCCCEEECCEEEEEECCCCCCCCCCCCCCCEEEEEECCCCCEEEECCCCEE
VSDTTFSNNGTIRAKNNISHKGTLFSNNGTLTSTQGSVFNNGRDINYKPPVVTPPTNSWW
EEEEEECCCCEEEECCCCCCCCEEEECCCEEEECCCCCCCCCCCCCCCCCEECCCCCHHH
SSWWSRSW
HHHHCCCC
>Mature Secondary Structure
MKKVLPRKISCLSAMIMFCLSGGAAFADASIVPVGGNVNLAANNVPVVNINQPGQDGVSH
CCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCEEEEECCEEEEECCCCCCCCCCC
NQYSQFDVGSQGAVLNNAQGSAQSQLAGAITANPNLSAGAAKVILNEINSSDKTLLNGMI
CCCCCCCCCCCCCEEECCCCCCHHHHEEEEECCCCCCCCHHHHHHHHCCCCHHHHHHHHH
EVAGQKADVIVANRSGITCNGCGFINTGTGVLTTGELQFKDKQFTGYSVTGGTVAFEGKG
HHCCCCEEEEEECCCCCEECCCCEEECCCCEEEECEEEEECCEECCEEECCCEEEEECCC
LQKGDVDYTAVIARAENINAAVQAKSLLVLAGKKTVTADLTRYINLENKEKSPEVLVDVS
CCCCCCCEEEEEEECCCCCEEEEEEEEEEEECCCEEEEEEEEEEECCCCCCCCCEEEEHH
QLGGMYAGKIILIANENGVGVNDSTPVSLRNNGELVTDGGDMLLSATSLSNAGKIAAGGN
HHCCEEECEEEEEECCCCCCCCCCCCEEECCCCCEEECCCCEEEEEECCCCCCEEEECCC
ANLATTVLSNQGDITANNALNISATSFSNAKDISAKNNIDIKSTTTSNNGTIVSQQGGVT
CCEEEEEECCCCCEEECCEEEEEECCCCCCCCCCCCCCCEEEEEECCCCCEEEECCCCEE
VSDTTFSNNGTIRAKNNISHKGTLFSNNGTLTSTQGSVFNNGRDINYKPPVVTPPTNSWW
EEEEEECCCCEEEECCCCCCCCEEEECCCEEEECCCCCCCCCCCCCCCCCEECCCCCHHH
SSWWSRSW
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2407716 [H]