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The map label for this gene is papH [H]

Identifier: 157372956

GI number: 157372956

Start: 5220370

End: 5220915

Strand: Reverse

Name: papH [H]

Synonym: Spro_4724

Alternate gene names: 157372956

Gene position: 5220915-5220370 (Counterclockwise)

Preceding gene: 157372957

Following gene: 157372955

Centisome position: 95.82

GC content: 48.9

Gene sequence:

>546_bases
ATGGTTCACTTTCGTGGGAAAGTAATGCCCCCTTGCATATTGACTCTGTTTTTATTTACCAGCAGTGCTCAGGCCGTACA
GCAGACTCAGGGCTGGGGACGGGTCAATATGCAAGGGGCCATTATTGATACCGCCTGCGCTATTGCCGCTGGCAGTCGTG
AACAGGTGATTGATATGGAGACGGTCCCGGTCGCCGATATTATTCGGGATGGACATGGGATGATCAAACCTTTCTCCATT
GAGTTAATCAATTGCGTATTAACCCGGTCCAATAACAAATTACCGAATTGGAAACATTTTCAGGTGACCTTTGATGGTGA
AACGGACGGCACATCATTTGGTGTGCAGGGTGAAGCAAAGGGCGTTGCGTTGCAAATTGCCGATGGACAGGGAAATATTG
CCACACCAGGGAAGCCCTTGCCGCTCGGTGATATTTCATTAGGGAGCATGCAACTGAATTATGCCATGCGGCTGGTAAGC
AATAGCCAGTCATTGCGGGCCGGAGTCTATTCTTCCGCTGTGCGTTTCAAACTGGATTATTACTGA

Upstream 100 bases:

>100_bases
CGCTTACCAGTAAGCCTGGTTGTAGTGCAATGAATTCAGCATGCGGGGCAGCCCGCATGCTTTATTACCGGAAGACACGT
TTTTGAATAGGGAATATTCA

Downstream 100 bases:

>100_bases
CGCGGATAAAAATTATTAAATAACAGGGTTGATGGCTATGGTGTTTATTCCTGCAAGGACGCGGTTTCGTATTCGGCTGT
TGAGGGTCTGTATTTGTCTG

Product: fimbrial protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 181; Mature: 181

Protein sequence:

>181_residues
MVHFRGKVMPPCILTLFLFTSSAQAVQQTQGWGRVNMQGAIIDTACAIAAGSREQVIDMETVPVADIIRDGHGMIKPFSI
ELINCVLTRSNNKLPNWKHFQVTFDGETDGTSFGVQGEAKGVALQIADGQGNIATPGKPLPLGDISLGSMQLNYAMRLVS
NSQSLRAGVYSSAVRFKLDYY

Sequences:

>Translated_181_residues
MVHFRGKVMPPCILTLFLFTSSAQAVQQTQGWGRVNMQGAIIDTACAIAAGSREQVIDMETVPVADIIRDGHGMIKPFSI
ELINCVLTRSNNKLPNWKHFQVTFDGETDGTSFGVQGEAKGVALQIADGQGNIATPGKPLPLGDISLGSMQLNYAMRLVS
NSQSLRAGVYSSAVRFKLDYY
>Mature_181_residues
MVHFRGKVMPPCILTLFLFTSSAQAVQQTQGWGRVNMQGAIIDTACAIAAGSREQVIDMETVPVADIIRDGHGMIKPFSI
ELINCVLTRSNNKLPNWKHFQVTFDGETDGTSFGVQGEAKGVALQIADGQGNIATPGKPLPLGDISLGSMQLNYAMRLVS
NSQSLRAGVYSSAVRFKLDYY

Specific function: PapH seems to anchor the pilus to the bacterial cell. In addition the stoichiometric relationship between papH and papA determines the pilus length [H]

COG id: COG3539

COG function: function code NU; P pilus assembly protein, pilin FimA

Gene ontology:

Cell location: Secreted. Fimbrium [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fimbrial protein family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008966
- InterPro:   IPR000259
- InterPro:   IPR014779 [H]

Pfam domain/function: PF00419 Fimbrial [H]

EC number: NA

Molecular weight: Translated: 19595; Mature: 19595

Theoretical pI: Translated: 8.06; Mature: 8.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVHFRGKVMPPCILTLFLFTSSAQAVQQTQGWGRVNMQGAIIDTACAIAAGSREQVIDME
CEEECCCCCCHHHHHHHHHCCCHHHHHHHCCCCEEEECCEEEEEEHHHCCCCCCCEEEEC
TVPVADIIRDGHGMIKPFSIELINCVLTRSNNKLPNWKHFQVTFDGETDGTSFGVQGEAK
CCCHHHHHHCCCCCCCCHHHEEEEEEEECCCCCCCCCEEEEEEECCCCCCCEECCCCCCC
GVALQIADGQGNIATPGKPLPLGDISLGSMQLNYAMRLVSNSQSLRAGVYSSAVRFKLDY
EEEEEEECCCCCCCCCCCCCCCCCCEECCEEHEEHEEECCCCCHHHHHHCCCEEEEEEEC
Y
C
>Mature Secondary Structure
MVHFRGKVMPPCILTLFLFTSSAQAVQQTQGWGRVNMQGAIIDTACAIAAGSREQVIDME
CEEECCCCCCHHHHHHHHHCCCHHHHHHHCCCCEEEECCEEEEEEHHHCCCCCCCEEEEC
TVPVADIIRDGHGMIKPFSIELINCVLTRSNNKLPNWKHFQVTFDGETDGTSFGVQGEAK
CCCHHHHHHCCCCCCCCHHHEEEEEEEECCCCCCCCCEEEEEEECCCCCCCEECCCCCCC
GVALQIADGQGNIATPGKPLPLGDISLGSMQLNYAMRLVSNSQSLRAGVYSSAVRFKLDY
EEEEEEECCCCCCCCCCCCCCCCCCEECCEEHEEHEEECCCCCHHHHHHCCCEEEEEEEC
Y
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2882856; 1357526; 2897064 [H]