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The map label for this gene is yafC [H]

Identifier: 157372916

GI number: 157372916

Start: 5174273

End: 5175244

Strand: Direct

Name: yafC [H]

Synonym: Spro_4684

Alternate gene names: 157372916

Gene position: 5174273-5175244 (Clockwise)

Preceding gene: 157372913

Following gene: 157372919

Centisome position: 94.96

GC content: 55.45

Gene sequence:

>972_bases
ATGATAAATAAGGTGGAGAACACATGGCTTATTACATGGAGTAATAGATTGCAGAGAAAATTTGACGATCTCCAATTAGG
CACGCTGGAGCTATTTTGTCTGGTTGCAGAGGTGGGCAGTTTTTCGGCCGCCGCCGTCTCTTCGGGTATTACCCCCGCCG
CGGTCAGCCGTTCCATCGCCCGGCTGGAGGATCGGTTAGGGGTTCGGCTGTTTGTCCGTTCCACTCGTCATATTCATCTG
ACTGATGCAGGTAAGAGCTATGCCGAGCAATGTCGAGAGGCAATCGCCCTCATTGATAATGCGGAGCGTCAAATACAAGG
CCAGCAGTTGGAGCCAGCCGGGCTGCTGCGCGTCAGCATTCCCACCCCCTACGCCCACTACCGCCTGTTGCCGGTCCTGG
CCGCCTTTAGCCAACGCTATCCTAAAATTCAATTGGCGCTGAATCTCAATAACGCTAACGTTGACCTCACTGATGGGGGA
TACGACCTGGCCATTCGCGGTTACCACCCTGCAGACTCAAACTTGATTGCCCGCAAGCTGGAGGATGCCGAATTGGTGGT
GGTTGCCGCACCGGATTACCTGGCGCGAGCGGGTACCCCCGTTCACCCGGAAGATCTGGCCCAGCATAACTGCATTCAGT
TTGAGCTACCCAGCACCGGCAAAAGCGCCCCATGGACGCTTAAGCACCATAACAAATCGATAGATGTCACCACGCGCGGC
AACGTGAGCTGCAACGGGGACTTTTTGGGGGGGTTAACGCTGGCAAAACATGGCATGGGCGTCTTTCAAACCTATCGCTT
TACCGTAGCGGACTTACTGGCGAGCGGTGAACTGGTGGAGGTCCTGACAGAATATGGCGGCACCACGCGGCCCTTTATTA
TGGTCTATCCGCATCAGCGGCATAAGTCACTGGCGCTGCGCAGCCTGATGGACTTTTTAGTCGTCACGCTGCAGCCGGCT
GCGCCACAATAA

Upstream 100 bases:

>100_bases
GAGGATCTCGCCCGTTTCATAACCCAAAATAGTCATCAGTTCTCTCCGTTAAATATCCCGTGCTTCCTAAGAGAAAGCCA
CTGTACTTCCCGATGGTGGG

Downstream 100 bases:

>100_bases
CCTTCGGCCGTGAAGCCGGCTCCCATGGCCGTTGAGGGGAGCCGGCACGCGGCCGAGAATAAAGCCTGACGTTAAAGAGT
GAGCAATATTGAAACGATCC

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MINKVENTWLITWSNRLQRKFDDLQLGTLELFCLVAEVGSFSAAAVSSGITPAAVSRSIARLEDRLGVRLFVRSTRHIHL
TDAGKSYAEQCREAIALIDNAERQIQGQQLEPAGLLRVSIPTPYAHYRLLPVLAAFSQRYPKIQLALNLNNANVDLTDGG
YDLAIRGYHPADSNLIARKLEDAELVVVAAPDYLARAGTPVHPEDLAQHNCIQFELPSTGKSAPWTLKHHNKSIDVTTRG
NVSCNGDFLGGLTLAKHGMGVFQTYRFTVADLLASGELVEVLTEYGGTTRPFIMVYPHQRHKSLALRSLMDFLVVTLQPA
APQ

Sequences:

>Translated_323_residues
MINKVENTWLITWSNRLQRKFDDLQLGTLELFCLVAEVGSFSAAAVSSGITPAAVSRSIARLEDRLGVRLFVRSTRHIHL
TDAGKSYAEQCREAIALIDNAERQIQGQQLEPAGLLRVSIPTPYAHYRLLPVLAAFSQRYPKIQLALNLNNANVDLTDGG
YDLAIRGYHPADSNLIARKLEDAELVVVAAPDYLARAGTPVHPEDLAQHNCIQFELPSTGKSAPWTLKHHNKSIDVTTRG
NVSCNGDFLGGLTLAKHGMGVFQTYRFTVADLLASGELVEVLTEYGGTTRPFIMVYPHQRHKSLALRSLMDFLVVTLQPA
APQ
>Mature_323_residues
MINKVENTWLITWSNRLQRKFDDLQLGTLELFCLVAEVGSFSAAAVSSGITPAAVSRSIARLEDRLGVRLFVRSTRHIHL
TDAGKSYAEQCREAIALIDNAERQIQGQQLEPAGLLRVSIPTPYAHYRLLPVLAAFSQRYPKIQLALNLNNANVDLTDGG
YDLAIRGYHPADSNLIARKLEDAELVVVAAPDYLARAGTPVHPEDLAQHNCIQFELPSTGKSAPWTLKHHNKSIDVTTRG
NVSCNGDFLGGLTLAKHGMGVFQTYRFTVADLLASGELVEVLTEYGGTTRPFIMVYPHQRHKSLALRSLMDFLVVTLQPA
APQ

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=286, Percent_Identity=33.5664335664336, Blast_Score=156, Evalue=1e-39,
Organism=Escherichia coli, GI1787128, Length=292, Percent_Identity=31.1643835616438, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI145693193, Length=295, Percent_Identity=30.5084745762712, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1787589, Length=291, Percent_Identity=26.8041237113402, Blast_Score=121, Evalue=8e-29,
Organism=Escherichia coli, GI1789440, Length=291, Percent_Identity=27.8350515463918, Blast_Score=117, Evalue=8e-28,
Organism=Escherichia coli, GI1789639, Length=294, Percent_Identity=28.2312925170068, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI87081978, Length=289, Percent_Identity=29.757785467128, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1788706, Length=263, Percent_Identity=28.8973384030418, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1789173, Length=190, Percent_Identity=33.6842105263158, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1787806, Length=125, Percent_Identity=35.2, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788481, Length=307, Percent_Identity=28.3387622149837, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1786448, Length=294, Percent_Identity=25.8503401360544, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI157672245, Length=117, Percent_Identity=37.6068376068376, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI145693105, Length=174, Percent_Identity=28.1609195402299, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1788748, Length=125, Percent_Identity=35.2, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1787601, Length=178, Percent_Identity=24.1573033707865, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI87082132, Length=277, Percent_Identity=25.9927797833935, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790262, Length=172, Percent_Identity=29.0697674418605, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI1787879, Length=151, Percent_Identity=29.8013245033113, Blast_Score=62, Evalue=7e-11,
Organism=Escherichia coli, GI87082024, Length=266, Percent_Identity=25.9398496240602, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35594; Mature: 35594

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINKVENTWLITWSNRLQRKFDDLQLGTLELFCLVAEVGSFSAAAVSSGITPAAVSRSIA
CCCCCCCEEEEEECHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHH
RLEDRLGVRLFVRSTRHIHLTDAGKSYAEQCREAIALIDNAERQIQGQQLEPAGLLRVSI
HHHHHCCEEEEEECCCEEEEECCCHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCEEEEEC
PTPYAHYRLLPVLAAFSQRYPKIQLALNLNNANVDLTDGGYDLAIRGYHPADSNLIARKL
CCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCEEEEECCCEEEEEEECCCCCCCHHHHCC
EDAELVVVAAPDYLARAGTPVHPEDLAQHNCIQFELPSTGKSAPWTLKHHNKSIDVTTRG
CCCCEEEEECCHHHHHCCCCCCHHHHHHCCCEEEECCCCCCCCCEEEEECCCEEEEEECC
NVSCNGDFLGGLTLAKHGMGVFQTYRFTVADLLASGELVEVLTEYGGTTRPFIMVYPHQR
CEEECCCEECCHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCEEEEECCCH
HKSLALRSLMDFLVVTLQPAAPQ
HHHHHHHHHHHHHHEEECCCCCC
>Mature Secondary Structure
MINKVENTWLITWSNRLQRKFDDLQLGTLELFCLVAEVGSFSAAAVSSGITPAAVSRSIA
CCCCCCCEEEEEECHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHH
RLEDRLGVRLFVRSTRHIHLTDAGKSYAEQCREAIALIDNAERQIQGQQLEPAGLLRVSI
HHHHHCCEEEEEECCCEEEEECCCHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCEEEEEC
PTPYAHYRLLPVLAAFSQRYPKIQLALNLNNANVDLTDGGYDLAIRGYHPADSNLIARKL
CCCHHHHHHHHHHHHHHCCCCEEEEEEEECCCEEEEECCCEEEEEEECCCCCCCHHHHCC
EDAELVVVAAPDYLARAGTPVHPEDLAQHNCIQFELPSTGKSAPWTLKHHNKSIDVTTRG
CCCCEEEEECCHHHHHCCCCCCHHHHHHCCCEEEECCCCCCCCCEEEEECCCEEEEEECC
NVSCNGDFLGGLTLAKHGMGVFQTYRFTVADLLASGELVEVLTEYGGTTRPFIMVYPHQR
CEEECCCEECCHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCEEEEECCCH
HKSLALRSLMDFLVVTLQPAAPQ
HHHHHHHHHHHHHHEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]