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The map label for this gene is iolG

Identifier: 157372890

GI number: 157372890

Start: 5145523

End: 5146536

Strand: Reverse

Name: iolG

Synonym: Spro_4658

Alternate gene names: 157372890

Gene position: 5146536-5145523 (Counterclockwise)

Preceding gene: 157372891

Following gene: 157372889

Centisome position: 94.45

GC content: 58.88

Gene sequence:

>1014_bases
ATGACACTGAACATTGGGGTTATTGGTACCGGCGCAATAGGTCGGGATCACATTCGTCGCTGCAGCAAAGTGTTGCAGGG
CAGCCGCATCGTGGCGGTCAACGATATTAACCGTGACAACGCCGCCAAGGTGGTGAGCGACCTGAAGCTGGACGCCAAGG
TGTATGACAATGGCCACGATCTGGTCAAGGCGGCGGACGTGCAGGCGGTGCTGGTGACCTCCTGGGGCCCGAGCCATGAA
GAGTTCGTGTTGGCGGCGATTGCCGCCGGCAAGCCGGTATTCTGCGAGAAGCCGCTGGCGGTCACTGCGCAGGGCTGTAA
AAACATCGTTGAGGCAGAGGCCAAACACGGCAAACGCCTGGTGCAGGTAGGCTTTATGCGCCCTTACGATCAGGGCTACC
GAGCACTGAAGCAGGTGCTGACCAGTGGGCAAATCGGCGAACCGCTGATGCTGCACTGTGCACACCGCAACCCAACCGTG
GGTGAAGCTTACACCACGGATATGGCGATCACCGACACCCTGATCCACGAGATCGACGTGCTGCGCTGGCTGCTGGATGA
CGACTATGTTTCGGTGCAGGTGGTGTTCCCGCGCAAAAGCGCCAAGGCATTCCCGCACCTGAAAGATCCGCAGATCGTGC
TGTTTGAAACCGCTAAAGGTACGCGCATCGACGTCGAAATCTTCGTTAACTGCCAGTACGGCTATGACATCCAGTGTGAA
GTGGTGGGTGAAACCGGCATTGCCAAACTGCCGGAGCCGTCTTCAGTACAGATGCGCAGCGGGGCCAAACTCTCTACCGA
AATTCTGACCGACTGGAAAGATCGCTTTATCGATGCTTACGACGTTGAGCTGCAAGGCTTTATCAACGACGTGCTGGCCG
GCAAGTTGACCGGGCCTTCTGCCTGGGACGGCTATGCTGCAGCCGTGACGGCCGATGCCTGCGTGGCTGCGCAGCTCAGC
GGCGAGATCGTACCTGTGACTCTGCCGCCGCGCCCGGCGTTCTACAACAAGTAG

Upstream 100 bases:

>100_bases
CTGCAAGAGAACATCGACAAGGCACGCGACTACTGATTAACACATTGCTTGATGACCCAGACCTTGCGTCTGCCGCAACT
ATTTGAAGAGGATAACGAAA

Downstream 100 bases:

>100_bases
TGTGTTGAACGCGGTACTCACGTTTAAAGGGGAATCACCATGAAGATCGCTTTTGATGTTGATGTCATCAGGGACCTGGG
CATTACTAAAATGGTTCAGC

Product: inositol 2-dehydrogenase

Products: NA

Alternate protein names: Myo-inositol 2-dehydrogenase; MI 2-dehydrogenase

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MTLNIGVIGTGAIGRDHIRRCSKVLQGSRIVAVNDINRDNAAKVVSDLKLDAKVYDNGHDLVKAADVQAVLVTSWGPSHE
EFVLAAIAAGKPVFCEKPLAVTAQGCKNIVEAEAKHGKRLVQVGFMRPYDQGYRALKQVLTSGQIGEPLMLHCAHRNPTV
GEAYTTDMAITDTLIHEIDVLRWLLDDDYVSVQVVFPRKSAKAFPHLKDPQIVLFETAKGTRIDVEIFVNCQYGYDIQCE
VVGETGIAKLPEPSSVQMRSGAKLSTEILTDWKDRFIDAYDVELQGFINDVLAGKLTGPSAWDGYAAAVTADACVAAQLS
GEIVPVTLPPRPAFYNK

Sequences:

>Translated_337_residues
MTLNIGVIGTGAIGRDHIRRCSKVLQGSRIVAVNDINRDNAAKVVSDLKLDAKVYDNGHDLVKAADVQAVLVTSWGPSHE
EFVLAAIAAGKPVFCEKPLAVTAQGCKNIVEAEAKHGKRLVQVGFMRPYDQGYRALKQVLTSGQIGEPLMLHCAHRNPTV
GEAYTTDMAITDTLIHEIDVLRWLLDDDYVSVQVVFPRKSAKAFPHLKDPQIVLFETAKGTRIDVEIFVNCQYGYDIQCE
VVGETGIAKLPEPSSVQMRSGAKLSTEILTDWKDRFIDAYDVELQGFINDVLAGKLTGPSAWDGYAAAVTADACVAAQLS
GEIVPVTLPPRPAFYNK
>Mature_336_residues
TLNIGVIGTGAIGRDHIRRCSKVLQGSRIVAVNDINRDNAAKVVSDLKLDAKVYDNGHDLVKAADVQAVLVTSWGPSHEE
FVLAAIAAGKPVFCEKPLAVTAQGCKNIVEAEAKHGKRLVQVGFMRPYDQGYRALKQVLTSGQIGEPLMLHCAHRNPTVG
EAYTTDMAITDTLIHEIDVLRWLLDDDYVSVQVVFPRKSAKAFPHLKDPQIVLFETAKGTRIDVEIFVNCQYGYDIQCEV
VGETGIAKLPEPSSVQMRSGAKLSTEILTDWKDRFIDAYDVELQGFINDVLAGKLTGPSAWDGYAAAVTADACVAAQLSG
EIVPVTLPPRPAFYNK

Specific function: Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose)

COG id: COG0673

COG function: function code R; Predicted dehydrogenases and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IOLG_SERP5 (A8GKW1)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001480879.1
- ProteinModelPortal:   A8GKW1
- SMR:   A8GKW1
- STRING:   A8GKW1
- GeneID:   5602910
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_4658
- eggNOG:   COG0673
- HOGENOM:   HBG612336
- OMA:   DWKDRFI
- ProtClustDB:   CLSK2785235
- BioCyc:   SPRO399741:SPRO_4658-MONOMER
- GO:   GO:0005488
- HAMAP:   MF_01671
- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104
- Gene3D:   G3DSA:3.40.50.720

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C

EC number: =1.1.1.18

Molecular weight: Translated: 36704; Mature: 36573

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLNIGVIGTGAIGRDHIRRCSKVLQGSRIVAVNDINRDNAAKVVSDLKLDAKVYDNGHD
CEEEEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHEECEEEECCCCC
LVKAADVQAVLVTSWGPSHEEFVLAAIAAGKPVFCEKPLAVTAQGCKNIVEAEAKHGKRL
EEEECCEEEEEEECCCCCCHHEEEEEECCCCCCEECCCCEEEHHHHHHHHHHHHHCCCEE
VQVGFMRPYDQGYRALKQVLTSGQIGEPLMLHCAHRNPTVGEAYTTDMAITDTLIHEIDV
EEEECCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCEEECCHHHHHHHHHHHHH
LRWLLDDDYVSVQVVFPRKSAKAFPHLKDPQIVLFETAKGTRIDVEIFVNCQYGYDIQCE
HHHHHCCCEEEEEEEECCCCCCCCCCCCCCCEEEEECCCCCEEEEEEEEEEECCCEEEEE
VVGETGIAKLPEPSSVQMRSGAKLSTEILTDWKDRFIDAYDVELQGFINDVLAGKLTGPS
EECCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHCCCCCCC
AWDGYAAAVTADACVAAQLSGEIVPVTLPPRPAFYNK
CCCCEEEEEEHHHHHHHHHCCCEEEEEECCCCCCCCC
>Mature Secondary Structure 
TLNIGVIGTGAIGRDHIRRCSKVLQGSRIVAVNDINRDNAAKVVSDLKLDAKVYDNGHD
EEEEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHEECEEEECCCCC
LVKAADVQAVLVTSWGPSHEEFVLAAIAAGKPVFCEKPLAVTAQGCKNIVEAEAKHGKRL
EEEECCEEEEEEECCCCCCHHEEEEEECCCCCCEECCCCEEEHHHHHHHHHHHHHCCCEE
VQVGFMRPYDQGYRALKQVLTSGQIGEPLMLHCAHRNPTVGEAYTTDMAITDTLIHEIDV
EEEECCCCHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCEEECCHHHHHHHHHHHHH
LRWLLDDDYVSVQVVFPRKSAKAFPHLKDPQIVLFETAKGTRIDVEIFVNCQYGYDIQCE
HHHHHCCCEEEEEEEECCCCCCCCCCCCCCCEEEEECCCCCEEEEEEEEEEECCCEEEEE
VVGETGIAKLPEPSSVQMRSGAKLSTEILTDWKDRFIDAYDVELQGFINDVLAGKLTGPS
EECCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHCCCCCCC
AWDGYAAAVTADACVAAQLSGEIVPVTLPPRPAFYNK
CCCCEEEEEEHHHHHHHHHCCCEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA