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The map label for this gene is hofQ [H]

Identifier: 157372838

GI number: 157372838

Start: 5081265

End: 5082506

Strand: Reverse

Name: hofQ [H]

Synonym: Spro_4606

Alternate gene names: 157372838

Gene position: 5082506-5081265 (Counterclockwise)

Preceding gene: 157372839

Following gene: 157372837

Centisome position: 93.28

GC content: 55.96

Gene sequence:

>1242_bases
ATGAAAGGATGCCGTTGGCTGGCCGGGTTGCTCTGGGGTGTGGTTATCGCCGGTGCAGCACAGGAGCAAGAACCCGTTTC
GCTGGAGTTTCAGGAGGCTCCCATTACGCTGGTGTTGCAGGCGCTGGCGGACTATCAACAGCTGAATATGGTCACCGCTG
CCGGTGTGGGGGGCAACCTGACGCTGAGGTTGGATAATGTGCCCTGGCACCAGGCACTGGCGGTGATTTTGCGTATGGGG
AAGTTGTCAATGACGCTGGAAGGGAATGTCATGATGGTCTCTCCTGAACCCAATGAGCAAGAAAAGCAGCGCCAACAGCA
GGCGTTGGCACAAAAACAGCCGCTGAAAAGCGTAACCCTGCCGTTGAGCCATGCCGATGCTGAAGAGGTTGCTGAAAACC
TGAACGCGCAGGGCGGAATATTGCTGAGCGAACGTGGCAGCGTGGTGGCAGATAAACGCACCAATGCGGTGTTGATCCGC
GATACAGCATCGATCGTGGCGTTATTAACGCAAAGGATCGGCGAAATGGATGCACCTTTGGCTCAGGTGCAATTGGCGAC
GCATATCGTCACCATCAACAGCGAGAGTTTACGTGAGCTTGGCGTGCGCTGGGGGTTGGCTCCGGACGACCGGCCGGCCA
GCTCATGGCAGATGGACGGTTTTAACGTCGGGTTACCACTGGAGCGCAGTGCTGTCAGCGCGGGTTTTCATCTGGCGCGA
ATTGGCGGGCGATTATTGGATCTGGAGTTGATGGCTTTGGAGCAGGAGAACCGGGTAGAAATCATTGCCAGCCCACGCCT
GCTGACTGCGAACCTGCAAACCGCCAGCATAAAGCAGGGGACTGAAATTCCCTATGAAGTGAACAGCGGCTCCAGCGGGG
CGACGTCGATGGAGTTCAAGGAAGCGGTACTGGGCATGGAGGTGACGCCGAAAATTTTGCCCAATGGCCGTATCACCCTG
ACGTTGCAAATCAGTCAGAACATGCCCGGGCGTTCAATCAGCCGTGCGGCCGGCGAGACGTTGGCGATAGATAAACAGGA
AATCAAAACTCAGGTGACGGTAAAAGATGGCGAAACCGTTGTTTTGGGAGGCGTATTTCAGCGCCATAGCGCCGAGGGGG
CCGATAAGGTTCCCGGAATTAGCGACGTGCCGTTGCTGGGTTCCCTGTTCAAACAGAGCAGCAAACAGCATAAACGGCGC
GAACTGGTGATATTCATTACTCCGACATTGATTAAGGCCTGA

Upstream 100 bases:

>100_bases
TTAAGGGGCAAGTAACGCTGAAAGCGAACCAGGGCGATCCGCTGTGTCCGGCCGCTGAGAATGCAGTGGTGTTGACCCTG
AGAAACCATAAGGAAGAAAA

Downstream 100 bases:

>100_bases
GCAACCGGGTGTGCGGTTCGTGGGAAATCGCCTAAAGTTGATGAGCAGATGCACTTTTTTATCACCTTCGGGGCATCTGC
GTTTGACGCTGCGACCGATT

Product: putative outer membrane porin HofQ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 413; Mature: 413

Protein sequence:

>413_residues
MKGCRWLAGLLWGVVIAGAAQEQEPVSLEFQEAPITLVLQALADYQQLNMVTAAGVGGNLTLRLDNVPWHQALAVILRMG
KLSMTLEGNVMMVSPEPNEQEKQRQQQALAQKQPLKSVTLPLSHADAEEVAENLNAQGGILLSERGSVVADKRTNAVLIR
DTASIVALLTQRIGEMDAPLAQVQLATHIVTINSESLRELGVRWGLAPDDRPASSWQMDGFNVGLPLERSAVSAGFHLAR
IGGRLLDLELMALEQENRVEIIASPRLLTANLQTASIKQGTEIPYEVNSGSSGATSMEFKEAVLGMEVTPKILPNGRITL
TLQISQNMPGRSISRAAGETLAIDKQEIKTQVTVKDGETVVLGGVFQRHSAEGADKVPGISDVPLLGSLFKQSSKQHKRR
ELVIFITPTLIKA

Sequences:

>Translated_413_residues
MKGCRWLAGLLWGVVIAGAAQEQEPVSLEFQEAPITLVLQALADYQQLNMVTAAGVGGNLTLRLDNVPWHQALAVILRMG
KLSMTLEGNVMMVSPEPNEQEKQRQQQALAQKQPLKSVTLPLSHADAEEVAENLNAQGGILLSERGSVVADKRTNAVLIR
DTASIVALLTQRIGEMDAPLAQVQLATHIVTINSESLRELGVRWGLAPDDRPASSWQMDGFNVGLPLERSAVSAGFHLAR
IGGRLLDLELMALEQENRVEIIASPRLLTANLQTASIKQGTEIPYEVNSGSSGATSMEFKEAVLGMEVTPKILPNGRITL
TLQISQNMPGRSISRAAGETLAIDKQEIKTQVTVKDGETVVLGGVFQRHSAEGADKVPGISDVPLLGSLFKQSSKQHKRR
ELVIFITPTLIKA
>Mature_413_residues
MKGCRWLAGLLWGVVIAGAAQEQEPVSLEFQEAPITLVLQALADYQQLNMVTAAGVGGNLTLRLDNVPWHQALAVILRMG
KLSMTLEGNVMMVSPEPNEQEKQRQQQALAQKQPLKSVTLPLSHADAEEVAENLNAQGGILLSERGSVVADKRTNAVLIR
DTASIVALLTQRIGEMDAPLAQVQLATHIVTINSESLRELGVRWGLAPDDRPASSWQMDGFNVGLPLERSAVSAGFHLAR
IGGRLLDLELMALEQENRVEIIASPRLLTANLQTASIKQGTEIPYEVNSGSSGATSMEFKEAVLGMEVTPKILPNGRITL
TLQISQNMPGRSISRAAGETLAIDKQEIKTQVTVKDGETVVLGGVFQRHSAEGADKVPGISDVPLLGSLFKQSSKQHKRR
ELVIFITPTLIKA

Specific function: Required for the use of extracellular DNA as a nutrient. Could be the porin responsible for transport of DNA across the outer membrane [H]

COG id: COG4796

COG function: function code U; Type II secretory pathway, component HofQ

Gene ontology:

Cell location: Cell outer membrane (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP D family [H]

Homologues:

Organism=Escherichia coli, GI1789793, Length=413, Percent_Identity=48.18401937046, Blast_Score=374, Evalue=1e-105,
Organism=Escherichia coli, GI87082242, Length=297, Percent_Identity=27.6094276094276, Blast_Score=101, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001775
- InterPro:   IPR005644
- InterPro:   IPR013355
- InterPro:   IPR011662
- InterPro:   IPR004846
- InterPro:   IPR004845
- InterPro:   IPR001814 [H]

Pfam domain/function: PF00263 Secretin; PF03958 Secretin_N; PF07660 STN [H]

EC number: NA

Molecular weight: Translated: 44611; Mature: 44611

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: PS00875 T2SP_D

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGCRWLAGLLWGVVIAGAAQEQEPVSLEFQEAPITLVLQALADYQQLNMVTAAGVGGNL
CCHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHCEEEEECCCCEE
TLRLDNVPWHQALAVILRMGKLSMTLEGNVMMVSPEPNEQEKQRQQQALAQKQPLKSVTL
EEEECCCCHHHHHHHHHHHCCEEEEEECCEEEECCCCCHHHHHHHHHHHHHHCCCCCEEC
PLSHADAEEVAENLNAQGGILLSERGSVVADKRTNAVLIRDTASIVALLTQRIGEMDAPL
CCCCCCHHHHHHHCCCCCCEEEECCCCEEECCCCCEEEEECHHHHHHHHHHHHCCCCCCH
AQVQLATHIVTINSESLRELGVRWGLAPDDRPASSWQMDGFNVGLPLERSAVSAGFHLAR
HHEEEEEEEEEECCHHHHHHHHHCCCCCCCCCCCCEECCCEEECCCCCHHHHHCCCHHHH
IGGRLLDLELMALEQENRVEIIASPRLLTANLQTASIKQGTEIPYEVNSGSSGATSMEFK
HCCEEEEEEEEEECCCCCEEEEECCEEEEECCCCCCCCCCCCCCEEECCCCCCCCHHHHH
EAVLGMEVTPKILPNGRITLTLQISQNMPGRSISRAAGETLAIDKQEIKTQVTVKDGETV
HHHHCCCCCCEECCCCEEEEEEEECCCCCCCHHHHHCCCEEEECHHHHEEEEEEECCCEE
VLGGVFQRHSAEGADKVPGISDVPLLGSLFKQSSKQHKRRELVIFITPTLIKA
EEECHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCEEEEEEECHHHCC
>Mature Secondary Structure
MKGCRWLAGLLWGVVIAGAAQEQEPVSLEFQEAPITLVLQALADYQQLNMVTAAGVGGNL
CCHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHCEEEEECCCCEE
TLRLDNVPWHQALAVILRMGKLSMTLEGNVMMVSPEPNEQEKQRQQQALAQKQPLKSVTL
EEEECCCCHHHHHHHHHHHCCEEEEEECCEEEECCCCCHHHHHHHHHHHHHHCCCCCEEC
PLSHADAEEVAENLNAQGGILLSERGSVVADKRTNAVLIRDTASIVALLTQRIGEMDAPL
CCCCCCHHHHHHHCCCCCCEEEECCCCEEECCCCCEEEEECHHHHHHHHHHHHCCCCCCH
AQVQLATHIVTINSESLRELGVRWGLAPDDRPASSWQMDGFNVGLPLERSAVSAGFHLAR
HHEEEEEEEEEECCHHHHHHHHHCCCCCCCCCCCCEECCCEEECCCCCHHHHHCCCHHHH
IGGRLLDLELMALEQENRVEIIASPRLLTANLQTASIKQGTEIPYEVNSGSSGATSMEFK
HCCEEEEEEEEEECCCCCEEEEECCEEEEECCCCCCCCCCCCCCEEECCCCCCCCHHHHH
EAVLGMEVTPKILPNGRITLTLQISQNMPGRSISRAAGETLAIDKQEIKTQVTVKDGETV
HHHHCCCCCCEECCCCEEEEEEEECCCCCCCHHHHHCCCEEEECHHHHEEEEEEECCCEE
VLGGVFQRHSAEGADKVPGISDVPLLGSLFKQSSKQHKRRELVIFITPTLIKA
EEECHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCEEEEEEECHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1309529; 9278503; 7901733 [H]