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The map label for this gene is yheS [H]

Identifier: 157372794

GI number: 157372794

Start: 5036194

End: 5038107

Strand: Direct

Name: yheS [H]

Synonym: Spro_4562

Alternate gene names: 157372794

Gene position: 5036194-5038107 (Clockwise)

Preceding gene: 157372789

Following gene: 157372805

Centisome position: 92.43

GC content: 58.05

Gene sequence:

>1914_bases
ATGATTGTATTTTCCTCGCTACAAATCCGACGCGGCACCCGCGTCCTGTTGGACAACGCCACGGCGACGGTTAATCCAGG
TCAGAAGGTCGGCCTGGTGGGTAAAAACGGCTGCGGCAAATCCACGTTGCTGTCATTGCTGAAGGGCGAGATGGCCGCGG
ACGGCGGCAGCTACACCTTTCCAAGCAACTGGGCCCTGGCCTGGGTTAATCAGGAAACACCGGCGCTGGACGTCCCTGCG
CTTGAGTATGTGATCGACGGCGACCGCGAATTCCGCCAGCTTGAAGCCGAATTGCAGGTGGCAAACGATAAAAACGACGG
CCACGCCATCGCCACATTGCACGGTAAACTGGATGCCCTTGATGCCTGGACCATCCGTTCTCGCGCCGCCAGCCTGCTGC
ACGGCCTGGGCTTTTCCAACGAACAGTTGCTCAATCCGGTACGCGCCTTCTCGGGCGGCTGGCGTATGCGCCTTAACCTG
GCACAAGCGTTGGTCTGTCGTTCAGACCTGCTGCTGCTCGACGAACCGACCAACCACCTGGATTTGGACGCGGTGATCTG
GCTGGAACGCTGGTTGAAAAGCTACCCAGGCACGCTGGTGCTGATTTCGCACGACCGCGATTTCCTTGATCCGATCGTCG
ATAAGATTCTGCATATCGAACAAGAAACCATTAACGAATATACCGGTAACTATTCCTCGTTCGAACGTCAACGTTCGACC
AAACTGGCACAGCAGCAGGCGCTGTACCAGAACCAACAGGAGAAAGTGGCGCATCTGCAAAGCTACATTGACCGCTTCCG
CGCGCAGGCCACCAAGGCCAAGCAGGCGCAAAGCCGTATCAAAATGCTTGAACGCATGGAGCTGATTGCACCGGCCCACG
TCGATAACCCGTTCAGCTTCAGCTTCCGCCAGCCGGAAAGCCTGCCGAACCCGCTGCTGCGCATGGAGAAGGTCAGCGCC
GGTTATGGCGACAAGGTGATCCTGAACTCGATCAAACTGAACCTGGTGCCCGGCTCACGTATCGGTCTGCTGGGCCGTAA
TGGCGCCGGTAAATCCACCCTGATCAAAATGCTGGCCGGTTCGCTGGAGCCGCTCAGCGGTGAGATTGGTCTGGCGAAGG
GCATCAAGCTGGGTTACTTCGCCCAGCATCAGTTGGAGTTCTTGCGCGCCGACGAATCCCCGTTGCAACATCTGAGCCGC
ATCGCCCCTCGGGTGCTGGAACAGCAGCTGCGCGACTATTTGGGCGGTTTTGGCTTCCAGGGCGATAAGGTCACCGAGAT
TACCGAACGTTTCTCCGGTGGCGAAAAGGCGCGGTTGGTGCTGGCGCTGATTGTCTGGCAGCGCCCTAACCTGCTGCTGC
TCGATGAACCGACCAACCACCTGGATCTGGATATGCGTCAGGCGCTGACCGAAGCGCTGATCGACTTTGAAGGCGCGTTA
GTGGTGGTCTCGCACGACCGTCACCTGTTGCGCTCCACCACTGACGATCTCTATCTGGTGCACGATGGCCAGGTGGAAGT
GTTCGACGGCGATTTGGACGACTATCAGCAATGGCTGGTTGACCTGCAACGTCAGGAAAACCAGCAGGACGCGCCGGACA
AGGAAAACAACGCCAACAGCGCGCAGGCCCGTAAAGATCAGAAACGTCGGGAAGCCGAGTTCCGCAGCCAGACTCAGCCG
CTGCGCAAGCAGATCGCCAAGCTGGAACAGCAGATGGAAAAACTGAGTGCCGAACTGGCGGCGGTGGAAGAGAAGCTGGC
GGATTCCGCGTTGTACGACATCAGCCGCAAGGCCGATTTGACGCGTTGTCTGCAACAGCAAAGCCAGGCCAAGTCCGCGT
TGGAAGAAACGGAAATGACCTGGCTGGATGCGCAAGAGCAGTTGGAACAGTTCACCAACGAGTTTGACCTTTAA

Upstream 100 bases:

>100_bases
TTTCCGTTACCATGCTCCGCAAAGACTAATAATAGGACAGTCTGCGTCCTGTTAACTTAGAACTCACTCAATTTAACATA
CTCTGAACATACGGCACTTT

Downstream 100 bases:

>100_bases
GCCTTATAAAAAGGCTTGTCCCCCAGAATGGTCGCGCGGTGCATAATGCGCCGCTGCGGCAGATAATCCGCGTTGGCGTA
ATGCTGCGTCACGCGGTTAT

Product: putative ABC transporter ATP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 637; Mature: 637

Protein sequence:

>637_residues
MIVFSSLQIRRGTRVLLDNATATVNPGQKVGLVGKNGCGKSTLLSLLKGEMAADGGSYTFPSNWALAWVNQETPALDVPA
LEYVIDGDREFRQLEAELQVANDKNDGHAIATLHGKLDALDAWTIRSRAASLLHGLGFSNEQLLNPVRAFSGGWRMRLNL
AQALVCRSDLLLLDEPTNHLDLDAVIWLERWLKSYPGTLVLISHDRDFLDPIVDKILHIEQETINEYTGNYSSFERQRST
KLAQQQALYQNQQEKVAHLQSYIDRFRAQATKAKQAQSRIKMLERMELIAPAHVDNPFSFSFRQPESLPNPLLRMEKVSA
GYGDKVILNSIKLNLVPGSRIGLLGRNGAGKSTLIKMLAGSLEPLSGEIGLAKGIKLGYFAQHQLEFLRADESPLQHLSR
IAPRVLEQQLRDYLGGFGFQGDKVTEITERFSGGEKARLVLALIVWQRPNLLLLDEPTNHLDLDMRQALTEALIDFEGAL
VVVSHDRHLLRSTTDDLYLVHDGQVEVFDGDLDDYQQWLVDLQRQENQQDAPDKENNANSAQARKDQKRREAEFRSQTQP
LRKQIAKLEQQMEKLSAELAAVEEKLADSALYDISRKADLTRCLQQQSQAKSALEETEMTWLDAQEQLEQFTNEFDL

Sequences:

>Translated_637_residues
MIVFSSLQIRRGTRVLLDNATATVNPGQKVGLVGKNGCGKSTLLSLLKGEMAADGGSYTFPSNWALAWVNQETPALDVPA
LEYVIDGDREFRQLEAELQVANDKNDGHAIATLHGKLDALDAWTIRSRAASLLHGLGFSNEQLLNPVRAFSGGWRMRLNL
AQALVCRSDLLLLDEPTNHLDLDAVIWLERWLKSYPGTLVLISHDRDFLDPIVDKILHIEQETINEYTGNYSSFERQRST
KLAQQQALYQNQQEKVAHLQSYIDRFRAQATKAKQAQSRIKMLERMELIAPAHVDNPFSFSFRQPESLPNPLLRMEKVSA
GYGDKVILNSIKLNLVPGSRIGLLGRNGAGKSTLIKMLAGSLEPLSGEIGLAKGIKLGYFAQHQLEFLRADESPLQHLSR
IAPRVLEQQLRDYLGGFGFQGDKVTEITERFSGGEKARLVLALIVWQRPNLLLLDEPTNHLDLDMRQALTEALIDFEGAL
VVVSHDRHLLRSTTDDLYLVHDGQVEVFDGDLDDYQQWLVDLQRQENQQDAPDKENNANSAQARKDQKRREAEFRSQTQP
LRKQIAKLEQQMEKLSAELAAVEEKLADSALYDISRKADLTRCLQQQSQAKSALEETEMTWLDAQEQLEQFTNEFDL
>Mature_637_residues
MIVFSSLQIRRGTRVLLDNATATVNPGQKVGLVGKNGCGKSTLLSLLKGEMAADGGSYTFPSNWALAWVNQETPALDVPA
LEYVIDGDREFRQLEAELQVANDKNDGHAIATLHGKLDALDAWTIRSRAASLLHGLGFSNEQLLNPVRAFSGGWRMRLNL
AQALVCRSDLLLLDEPTNHLDLDAVIWLERWLKSYPGTLVLISHDRDFLDPIVDKILHIEQETINEYTGNYSSFERQRST
KLAQQQALYQNQQEKVAHLQSYIDRFRAQATKAKQAQSRIKMLERMELIAPAHVDNPFSFSFRQPESLPNPLLRMEKVSA
GYGDKVILNSIKLNLVPGSRIGLLGRNGAGKSTLIKMLAGSLEPLSGEIGLAKGIKLGYFAQHQLEFLRADESPLQHLSR
IAPRVLEQQLRDYLGGFGFQGDKVTEITERFSGGEKARLVLALIVWQRPNLLLLDEPTNHLDLDMRQALTEALIDFEGAL
VVVSHDRHLLRSTTDDLYLVHDGQVEVFDGDLDDYQQWLVDLQRQENQQDAPDKENNANSAQARKDQKRREAEFRSQTQP
LRKQIAKLEQQMEKLSAELAAVEEKLADSALYDISRKADLTRCLQQQSQAKSALEETEMTWLDAQEQLEQFTNEFDL

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=525, Percent_Identity=38.0952380952381, Blast_Score=360, Evalue=2e-99,
Organism=Homo sapiens, GI27881506, Length=512, Percent_Identity=36.328125, Blast_Score=320, Evalue=3e-87,
Organism=Homo sapiens, GI10947137, Length=512, Percent_Identity=36.328125, Blast_Score=320, Evalue=3e-87,
Organism=Homo sapiens, GI10947135, Length=538, Percent_Identity=34.2007434944238, Blast_Score=267, Evalue=2e-71,
Organism=Homo sapiens, GI69354671, Length=538, Percent_Identity=34.2007434944238, Blast_Score=267, Evalue=2e-71,
Organism=Escherichia coli, GI1789751, Length=631, Percent_Identity=84.7860538827258, Blast_Score=1112, Evalue=0.0,
Organism=Escherichia coli, GI1787041, Length=527, Percent_Identity=33.3965844402277, Blast_Score=300, Evalue=2e-82,
Organism=Escherichia coli, GI1787182, Length=638, Percent_Identity=28.5266457680251, Blast_Score=227, Evalue=2e-60,
Organism=Escherichia coli, GI2367384, Length=538, Percent_Identity=31.9702602230483, Blast_Score=226, Evalue=3e-60,
Organism=Escherichia coli, GI1788165, Length=201, Percent_Identity=33.3333333333333, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI87081782, Length=581, Percent_Identity=25.1290877796902, Blast_Score=90, Evalue=5e-19,
Organism=Escherichia coli, GI48994997, Length=246, Percent_Identity=26.8292682926829, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1787758, Length=213, Percent_Identity=27.6995305164319, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI87081791, Length=204, Percent_Identity=29.4117647058824, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1787164, Length=216, Percent_Identity=26.8518518518519, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1787547, Length=201, Percent_Identity=26.865671641791, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI48994883, Length=219, Percent_Identity=28.310502283105, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1788761, Length=226, Percent_Identity=26.1061946902655, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI87081709, Length=223, Percent_Identity=21.9730941704036, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI1788506, Length=303, Percent_Identity=22.7722772277228, Blast_Score=64, Evalue=3e-11,
Organism=Escherichia coli, GI1789891, Length=207, Percent_Identity=26.0869565217391, Blast_Score=63, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17553372, Length=530, Percent_Identity=38.3018867924528, Blast_Score=350, Evalue=1e-96,
Organism=Caenorhabditis elegans, GI17555318, Length=525, Percent_Identity=34.8571428571429, Blast_Score=315, Evalue=6e-86,
Organism=Caenorhabditis elegans, GI17559834, Length=547, Percent_Identity=32.5411334552102, Blast_Score=298, Evalue=4e-81,
Organism=Caenorhabditis elegans, GI71996809, Length=204, Percent_Identity=31.3725490196078, Blast_Score=68, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71988343, Length=264, Percent_Identity=25, Blast_Score=67, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17556528, Length=200, Percent_Identity=28, Blast_Score=65, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6321121, Length=544, Percent_Identity=35.4779411764706, Blast_Score=340, Evalue=5e-94,
Organism=Saccharomyces cerevisiae, GI6320874, Length=529, Percent_Identity=35.538752362949, Blast_Score=328, Evalue=1e-90,
Organism=Saccharomyces cerevisiae, GI6325030, Length=394, Percent_Identity=29.4416243654822, Blast_Score=152, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6324314, Length=391, Percent_Identity=28.9002557544757, Blast_Score=144, Evalue=6e-35,
Organism=Saccharomyces cerevisiae, GI6323278, Length=394, Percent_Identity=27.1573604060914, Blast_Score=141, Evalue=4e-34,
Organism=Drosophila melanogaster, GI24666836, Length=517, Percent_Identity=38.1044487427466, Blast_Score=373, Evalue=1e-103,
Organism=Drosophila melanogaster, GI24642252, Length=526, Percent_Identity=37.2623574144487, Blast_Score=347, Evalue=2e-95,
Organism=Drosophila melanogaster, GI18859989, Length=526, Percent_Identity=37.2623574144487, Blast_Score=347, Evalue=2e-95,
Organism=Drosophila melanogaster, GI24641342, Length=525, Percent_Identity=33.9047619047619, Blast_Score=303, Evalue=3e-82,
Organism=Drosophila melanogaster, GI116007184, Length=206, Percent_Identity=26.6990291262136, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI221500365, Length=209, Percent_Identity=26.3157894736842, Blast_Score=69, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 71753; Mature: 71753

Theoretical pI: Translated: 5.35; Mature: 5.35

Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVFSSLQIRRGTRVLLDNATATVNPGQKVGLVGKNGCGKSTLLSLLKGEMAADGGSYTF
CEEECCEEECCCCEEEEECCEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCC
PSNWALAWVNQETPALDVPALEYVIDGDREFRQLEAELQVANDKNDGHAIATLHGKLDAL
CCCCEEEEECCCCCCCCCCHHHEEECCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCCHH
DAWTIRSRAASLLHGLGFSNEQLLNPVRAFSGGWRMRLNLAQALVCRSDLLLLDEPTNHL
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEHHHHHHHHHHCCEEEEECCCCCC
DLDAVIWLERWLKSYPGTLVLISHDRDFLDPIVDKILHIEQETINEYTGNYSSFERQRST
CHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
KLAQQQALYQNQQEKVAHLQSYIDRFRAQATKAKQAQSRIKMLERMELIAPAHVDNPFSF
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
SFRQPESLPNPLLRMEKVSAGYGDKVILNSIKLNLVPGSRIGLLGRNGAGKSTLIKMLAG
CCCCCCCCCCHHHHHHHHCCCCCCEEEEEEEEEEEECCCCEEEEECCCCCHHHHHHHHHC
SLEPLSGEIGLAKGIKLGYFAQHQLEFLRADESPLQHLSRIAPRVLEQQLRDYLGGFGFQ
CCCCCCCCCCHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GDKVTEITERFSGGEKARLVLALIVWQRPNLLLLDEPTNHLDLDMRQALTEALIDFEGAL
CCHHHHHHHHHCCCCHHHHHHHHHEECCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCEE
VVVSHDRHLLRSTTDDLYLVHDGQVEVFDGDLDDYQQWLVDLQRQENQQDAPDKENNANS
EEEECCCHHHHCCCCCEEEEECCEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCH
AQARKDQKRREAEFRSQTQPLRKQIAKLEQQMEKLSAELAAVEEKLADSALYDISRKADL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TRCLQQQSQAKSALEETEMTWLDAQEQLEQFTNEFDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIVFSSLQIRRGTRVLLDNATATVNPGQKVGLVGKNGCGKSTLLSLLKGEMAADGGSYTF
CEEECCEEECCCCEEEEECCEEECCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCC
PSNWALAWVNQETPALDVPALEYVIDGDREFRQLEAELQVANDKNDGHAIATLHGKLDAL
CCCCEEEEECCCCCCCCCCHHHEEECCCHHHHHHHHHHHCCCCCCCCCEEEEECCCCCHH
DAWTIRSRAASLLHGLGFSNEQLLNPVRAFSGGWRMRLNLAQALVCRSDLLLLDEPTNHL
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCEEEHHHHHHHHHHCCEEEEECCCCCC
DLDAVIWLERWLKSYPGTLVLISHDRDFLDPIVDKILHIEQETINEYTGNYSSFERQRST
CHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
KLAQQQALYQNQQEKVAHLQSYIDRFRAQATKAKQAQSRIKMLERMELIAPAHVDNPFSF
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
SFRQPESLPNPLLRMEKVSAGYGDKVILNSIKLNLVPGSRIGLLGRNGAGKSTLIKMLAG
CCCCCCCCCCHHHHHHHHCCCCCCEEEEEEEEEEEECCCCEEEEECCCCCHHHHHHHHHC
SLEPLSGEIGLAKGIKLGYFAQHQLEFLRADESPLQHLSRIAPRVLEQQLRDYLGGFGFQ
CCCCCCCCCCHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GDKVTEITERFSGGEKARLVLALIVWQRPNLLLLDEPTNHLDLDMRQALTEALIDFEGAL
CCHHHHHHHHHCCCCHHHHHHHHHEECCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCEE
VVVSHDRHLLRSTTDDLYLVHDGQVEVFDGDLDDYQQWLVDLQRQENQQDAPDKENNANS
EEEECCCHHHHCCCCCEEEEECCEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCH
AQARKDQKRREAEFRSQTQPLRKQIAKLEQQMEKLSAELAAVEEKLADSALYDISRKADL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TRCLQQQSQAKSALEETEMTWLDAQEQLEQFTNEFDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]