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The map label for this gene is kefG

Identifier: 157372793

GI number: 157372793

Start: 5035509

End: 5036060

Strand: Reverse

Name: kefG

Synonym: Spro_4561

Alternate gene names: 157372793

Gene position: 5036060-5035509 (Counterclockwise)

Preceding gene: 157372795

Following gene: 157372792

Centisome position: 92.42

GC content: 56.16

Gene sequence:

>552_bases
ATGTCGCAGCCGCCGAAGGTCTTGCTGCTGTATGCCCATCCGGAATCCCAGGACTCGGTCGCGAATCGGGTTTTGCTTCG
ACCGGCACAGCAGTTGGAACATGTCACCGTGCACGATTTATACGCGCACTATCCTGATTTTTTTATTGATATTCACCACG
AACAACAACTGCTGCGTGAACATCAGGTCATTGTTTTTCAACATCCTCTCTATACCTACAGTTGCCCGGCCCTGCTGAAA
GAATGGCTGGATCGCGTGCTGTCGCGTGGTTTTGCCAGCGGCATGGGGGGCAATGCGCTGGCGGGAAAATACTGGCGTTC
GGTGATCACCACCGGTGAACCGGAGGGCGCCTACCGTACCGGCGGTTATAACCGCTATCCGATAGAAGATATTTTACGCC
CGTTTGAATTGACCGCCGCCATGTGCCATATGCACTGGCTGACGCCGATGCTGGTGTATTGGGCGCGTCGGCAGAAGCCA
GAGGTGCTGGAAAGCCATGCCACGGCGTATGGCGACTGGTTGCGCAACCCGCTGCCACACGGAGGGAGGTAA

Upstream 100 bases:

>100_bases
GTGAGTTCTAAGTTAACAGGACGCAGACTGTCCTATTATTAGTCTTTGCGGAGCATGGTAACGGAAAACCGCTACCCTGA
CGACGCTTTGGAGGGGAATG

Downstream 100 bases:

>100_bases
ACATGGAAGGCTCAACCTTACTGACCGCAATTTTACTGTTTCTGTTCGCTGCGGTGGTCACGGTGCCGATTGCACGCCGC
CTGGGTATTGGCGCGGTCTT

Product: glutathione-regulated potassium-efflux system ancillary protein KefG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 183; Mature: 182

Protein sequence:

>183_residues
MSQPPKVLLLYAHPESQDSVANRVLLRPAQQLEHVTVHDLYAHYPDFFIDIHHEQQLLREHQVIVFQHPLYTYSCPALLK
EWLDRVLSRGFASGMGGNALAGKYWRSVITTGEPEGAYRTGGYNRYPIEDILRPFELTAAMCHMHWLTPMLVYWARRQKP
EVLESHATAYGDWLRNPLPHGGR

Sequences:

>Translated_183_residues
MSQPPKVLLLYAHPESQDSVANRVLLRPAQQLEHVTVHDLYAHYPDFFIDIHHEQQLLREHQVIVFQHPLYTYSCPALLK
EWLDRVLSRGFASGMGGNALAGKYWRSVITTGEPEGAYRTGGYNRYPIEDILRPFELTAAMCHMHWLTPMLVYWARRQKP
EVLESHATAYGDWLRNPLPHGGR
>Mature_182_residues
SQPPKVLLLYAHPESQDSVANRVLLRPAQQLEHVTVHDLYAHYPDFFIDIHHEQQLLREHQVIVFQHPLYTYSCPALLKE
WLDRVLSRGFASGMGGNALAGKYWRSVITTGEPEGAYRTGGYNRYPIEDILRPFELTAAMCHMHWLTPMLVYWARRQKPE
VLESHATAYGDWLRNPLPHGGR

Specific function: Required for full activity of kefB

COG id: COG2249

COG function: function code R; Putative NADPH-quinone reductase (modulator of drug activity B)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD(P)H dehydrogenase (quinone) family. KefG subfamily

Homologues:

Organism=Homo sapiens, GI156564357, Length=222, Percent_Identity=29.7297297297297, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI1789750, Length=183, Percent_Identity=80.8743169398907, Blast_Score=311, Evalue=1e-86,
Organism=Escherichia coli, GI1786231, Length=165, Percent_Identity=41.8181818181818, Blast_Score=119, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KEFG_SERP5 (A8GKL4)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001480782.1
- ProteinModelPortal:   A8GKL4
- SMR:   A8GKL4
- STRING:   A8GKL4
- GeneID:   5602661
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_4561
- eggNOG:   COG2249
- HOGENOM:   HBG532247
- OMA:   TTGEPEG
- ProtClustDB:   PRK04930
- BioCyc:   SPRO399741:SPRO_4561-MONOMER
- HAMAP:   MF_01415
- InterPro:   IPR003680

Pfam domain/function: PF02525 Flavodoxin_2

EC number: 1.6.99.- [C]

Molecular weight: Translated: 21170; Mature: 21039

Theoretical pI: Translated: 7.44; Mature: 7.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQPPKVLLLYAHPESQDSVANRVLLRPAQQLEHVTVHDLYAHYPDFFIDIHHEQQLLRE
CCCCCCEEEEEECCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHH
HQVIVFQHPLYTYSCPALLKEWLDRVLSRGFASGMGGNALAGKYWRSVITTGEPEGAYRT
CCEEEEECCCHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCEEC
GGYNRYPIEDILRPFELTAAMCHMHWLTPMLVYWARRQKPEVLESHATAYGDWLRNPLPH
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCC
GGR
CCC
>Mature Secondary Structure 
SQPPKVLLLYAHPESQDSVANRVLLRPAQQLEHVTVHDLYAHYPDFFIDIHHEQQLLRE
CCCCCEEEEEECCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHH
HQVIVFQHPLYTYSCPALLKEWLDRVLSRGFASGMGGNALAGKYWRSVITTGEPEGAYRT
CCEEEEECCCHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCEEC
GGYNRYPIEDILRPFELTAAMCHMHWLTPMLVYWARRQKPEVLESHATAYGDWLRNPLPH
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCC
GGR
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA