Click here to switch to the map view.

The map label for this gene is uppP

Identifier: 157372527

GI number: 157372527

Start: 4761318

End: 4762142

Strand: Reverse

Name: uppP

Synonym: Spro_4294

Alternate gene names: 157372527

Gene position: 4762142-4761318 (Counterclockwise)

Preceding gene: 157372528

Following gene: 157372524

Centisome position: 87.4

GC content: 53.58

Gene sequence:

>825_bases
ATGGCGGACATGCATTCACTGTTTATTGCGTTTGTTCTTGGGGTGGTCGAAGGGTTAACTGAATTTTTACCGGTGTCATC
TACCGGGCACATGATTATTGTCGGCGAGTGGCTGGGTTTTACCGGCGATAAGGCCAAAACCTTTGAGGTGATCATCCAGC
TGGGGTCGATTCTGGCGGTGGTGGTGATGTTCTGGCGTCGCTTGTTCGGGCTGATCGGCATTCATTTCGGTGGTAAGCCG
GTTGAGCATGAAGGCAAAACGACGGGTCATTTGAAACTGGGCCATATTCTGCTGGCGATGATCCCGGCGGTGGTGCTGGG
GCTGCTGTTCCATGACGTTATCAAGTCGCTATTTGCACCGAAAAACGTGATGTATGCGCTGGTGGTGGGTGGTTTCCTGC
TGCTGGCAGCGGAATGGTTGAAGCCGAAAAAGCCGAGTGCTGAAGGGCTTGATGACATCACCTACCGCCAGGCGTTTATG
ATTGGTTGCTTCCAATGTCTGGCACTGTGGCCGGGCTTCTCCCGCTCAGGTTCCACCATTGCCGGTGGCATGCTGGTGGG
CGTGAATCGTTACGCGGCTGCGGAGTTCTCATTCATTCTGGCGGTGCCGATGATGATTGGTGCCAGTGGGCTGGATTTGT
ACAAGAGTCTGCACTTCCTGACGATGGGCGATTTACCGATGTTTGCAGTCGGCTTTGCCACTGCTTTCGTGGTAGCACTG
ATCGCGATCAAGACCTTCCTGACGCTGATCAAACGCATCTCGTTTGTGCCGTTTGCCATCTATCGCTTTATCGTGGCCGG
CGTGGTTTACATGGTCTTCATGTAA

Upstream 100 bases:

>100_bases
TTAAATTGGTCTGAACCTGAGAATTGTTTTAGCGGCAATGTATTGAACACTGCCGCTTTTTTATGTTTATAGCCGTAAAT
TTATAGGGTGATCGAAGCAC

Downstream 100 bases:

>100_bases
GCCGAGTGGCAATAAGAAACCCCGCGCTGCGGGGTTTTTTTATGCCTGATCGAGAGGGATATCCTGAGTTTGTTTCCACT
CGGCTAGCGCTTGTTGGCGG

Product: undecaprenyl pyrophosphate phosphatase

Products: NA

Alternate protein names: Bacitracin resistance protein; Undecaprenyl pyrophosphate phosphatase

Number of amino acids: Translated: 274; Mature: 273

Protein sequence:

>274_residues
MADMHSLFIAFVLGVVEGLTEFLPVSSTGHMIIVGEWLGFTGDKAKTFEVIIQLGSILAVVVMFWRRLFGLIGIHFGGKP
VEHEGKTTGHLKLGHILLAMIPAVVLGLLFHDVIKSLFAPKNVMYALVVGGFLLLAAEWLKPKKPSAEGLDDITYRQAFM
IGCFQCLALWPGFSRSGSTIAGGMLVGVNRYAAAEFSFILAVPMMIGASGLDLYKSLHFLTMGDLPMFAVGFATAFVVAL
IAIKTFLTLIKRISFVPFAIYRFIVAGVVYMVFM

Sequences:

>Translated_274_residues
MADMHSLFIAFVLGVVEGLTEFLPVSSTGHMIIVGEWLGFTGDKAKTFEVIIQLGSILAVVVMFWRRLFGLIGIHFGGKP
VEHEGKTTGHLKLGHILLAMIPAVVLGLLFHDVIKSLFAPKNVMYALVVGGFLLLAAEWLKPKKPSAEGLDDITYRQAFM
IGCFQCLALWPGFSRSGSTIAGGMLVGVNRYAAAEFSFILAVPMMIGASGLDLYKSLHFLTMGDLPMFAVGFATAFVVAL
IAIKTFLTLIKRISFVPFAIYRFIVAGVVYMVFM
>Mature_273_residues
ADMHSLFIAFVLGVVEGLTEFLPVSSTGHMIIVGEWLGFTGDKAKTFEVIIQLGSILAVVVMFWRRLFGLIGIHFGGKPV
EHEGKTTGHLKLGHILLAMIPAVVLGLLFHDVIKSLFAPKNVMYALVVGGFLLLAAEWLKPKKPSAEGLDDITYRQAFMI
GCFQCLALWPGFSRSGSTIAGGMLVGVNRYAAAEFSFILAVPMMIGASGLDLYKSLHFLTMGDLPMFAVGFATAFVVALI
AIKTFLTLIKRISFVPFAIYRFIVAGVVYMVFM

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=273, Percent_Identity=82.051282051282, Blast_Score=445, Evalue=1e-126,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP_SERP5 (A8GJU8)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001480516.1
- STRING:   A8GJU8
- GeneID:   5604464
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_4294
- eggNOG:   COG1968
- HOGENOM:   HBG391969
- OMA:   LVQCLAM
- ProtClustDB:   PRK00281
- BioCyc:   SPRO399741:SPRO_4294-MONOMER
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824
- TIGRFAMs:   TIGR00753

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 29847; Mature: 29716

Theoretical pI: Translated: 9.36; Mature: 9.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x91fcc48)-; HASH(0x112bc45c)-; HASH(0x112a84f4)-; HASH(0x112ab6a4)-; HASH(0x112ab4a0)-; HASH(0x112b5614)-; HASH(0x118f59b4)-; HASH(0x1104e084)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADMHSLFIAFVLGVVEGLTEFLPVSSTGHMIIVGEWLGFTGDKAKTFEVIIQLGSILAV
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHH
VVMFWRRLFGLIGIHFGGKPVEHEGKTTGHLKLGHILLAMIPAVVLGLLFHDVIKSLFAP
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KNVMYALVVGGFLLLAAEWLKPKKPSAEGLDDITYRQAFMIGCFQCLALWPGFSRSGSTI
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
AGGMLVGVNRYAAAEFSFILAVPMMIGASGLDLYKSLHFLTMGDLPMFAVGFATAFVVAL
HCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHEECCCHHHHHHHHHHHHHHH
IAIKTFLTLIKRISFVPFAIYRFIVAGVVYMVFM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
>Mature Secondary Structure 
ADMHSLFIAFVLGVVEGLTEFLPVSSTGHMIIVGEWLGFTGDKAKTFEVIIQLGSILAV
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHH
VVMFWRRLFGLIGIHFGGKPVEHEGKTTGHLKLGHILLAMIPAVVLGLLFHDVIKSLFAP
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KNVMYALVVGGFLLLAAEWLKPKKPSAEGLDDITYRQAFMIGCFQCLALWPGFSRSGSTI
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCH
AGGMLVGVNRYAAAEFSFILAVPMMIGASGLDLYKSLHFLTMGDLPMFAVGFATAFVVAL
HCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHEECCCHHHHHHHHHHHHHHH
IAIKTFLTLIKRISFVPFAIYRFIVAGVVYMVFM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA