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The map label for this gene is bglC [H]

Identifier: 157372454

GI number: 157372454

Start: 4680442

End: 4681845

Strand: Reverse

Name: bglC [H]

Synonym: Spro_4221

Alternate gene names: 157372454

Gene position: 4681845-4680442 (Counterclockwise)

Preceding gene: 157372455

Following gene: 157372452

Centisome position: 85.92

GC content: 56.84

Gene sequence:

>1404_bases
ATGAGCGTATTTCCGAAGGATTTCCTGTGGGGCGCGGCGACCGCGTCTTACCAGGTTGAGGGCGGCTTTGATGCCGACGG
CAAGGGCCTGTCCAACTGGGACTTGTTCTCCCACCTGCCCGGCACCACTTATCAGGGTACCAACGGCGACGTCGCGGTCG
ATCACTACCATCGCTTTCGCGAAGACGTAGCGCTGATGGCCGAATTGGGGATGCAGACCTACCGATTTTCGATCTCGTGG
CCACGGTTGCTGCCGCAGGGGCGGGGCGAGGTGAATGAGGCCGGGATCCAATTCTACAGCGATCTGATCGACGAACTGTT
GAAGCACAACATCAAACCGATGATCACCCTGTACCACTGGGATCTGCCGCAGGCGCTGCAAGAAGAATTTGGCGGTTGGG
AATCGCGTGAGATCGTCGATGCTTTCGATGAATATGCCCGTCTGTGTTATCAGCGTTTCGGCGACCGCGTCGAGCTGTGG
TCTACCTTTAACGAAACCATCGTGTTTATCGGCATGGGCTATATCACCGGAGCGCATCCGCCCAAGTTGACCGATCCGAA
GAAGGGCATTCAGGCCTGTCACCATGTGTTCCTGGCCAATGCCCGCGCGGTAAAAAGCTTCCGCGAAATGAAGATCAACG
GTCAGATCGGCTTCGTCAACGTGCTGCAACCTAACGATCCGATCAGCGACTCGCCAGAAGATCGCCGCGCCTGCGAGTTA
GCCGAGGGGATCTTCACCCACTGGCTGTACGATCCGGTGTTGAAGGGCGAATACCCGGCAGAGCTGTTGGCGATGGCGCA
GCAGGCCTTTGGCGTACCTTATTTTGCACCGGGCGATGAGGCGTTGCTGAAGGGCAACATCGTCGATTTTATCGGTCTTA
ATTACTACAAGCGCGAAATGGTGGCACATAACGACGATGTCGAGGGCTACGCGATCAATACCAGTGGCCAGAAGGGCAGC
GGGCGTGAACTGGGCTTTAAGGGGCTGTTCAAACTGGTGCGCAACCCGAACGGGGTTTATACCGACTGGGACTGGGAGGT
TTATCCGCAGGGGCTGACCGATGCCATTGGCCGCATCGTCAAACGCTATGGCAACATTCCGATCTACATTACCGAGAACG
GGTTGGGTGCCAAGGATCCGATCGTCGAGGGGGAAGTGCGCGATCAACCGCGCATAGACTATCTGCGCGATCATATTCAG
GCGATCGGTGCGGCGATCGAGCAGGGTGCCGATGTGCGCGGTTACTACCCCTGGTCGTTTATCGATCTGCTTTCCTGGCT
CAACGGCTATCAGAAGCAGTACGGCTTTGTGTATGTCGATCACGACAACAATCTGGCGCGCAAGAAGAAGCAGAGTTTTG
GCTGGTATCAGCGGGTGATCGCCAGCCACGGTGAGCAGCTGTAA

Upstream 100 bases:

>100_bases
ACGCGCAGGACCACATCATGAACGCCATGCTGGCGCGCGATCTGGTGGAGGAACTGGTGAGAATTTACCGATTACTGGAG
CAGAACGGGGTGAAAAACCA

Downstream 100 bases:

>100_bases
CTCGCGAACGGGGGGGCGGTTCAGTACAGCGATCCGTGCTCCTGATCCAGGTACAGTAACTGTTGCTCGATCACCAACAG
GACTTTTTTCAACTGCTGCG

Product: beta-glucosidase

Products: NA

Alternate protein names: 6-phospho-beta-glucosidase [H]

Number of amino acids: Translated: 467; Mature: 466

Protein sequence:

>467_residues
MSVFPKDFLWGAATASYQVEGGFDADGKGLSNWDLFSHLPGTTYQGTNGDVAVDHYHRFREDVALMAELGMQTYRFSISW
PRLLPQGRGEVNEAGIQFYSDLIDELLKHNIKPMITLYHWDLPQALQEEFGGWESREIVDAFDEYARLCYQRFGDRVELW
STFNETIVFIGMGYITGAHPPKLTDPKKGIQACHHVFLANARAVKSFREMKINGQIGFVNVLQPNDPISDSPEDRRACEL
AEGIFTHWLYDPVLKGEYPAELLAMAQQAFGVPYFAPGDEALLKGNIVDFIGLNYYKREMVAHNDDVEGYAINTSGQKGS
GRELGFKGLFKLVRNPNGVYTDWDWEVYPQGLTDAIGRIVKRYGNIPIYITENGLGAKDPIVEGEVRDQPRIDYLRDHIQ
AIGAAIEQGADVRGYYPWSFIDLLSWLNGYQKQYGFVYVDHDNNLARKKKQSFGWYQRVIASHGEQL

Sequences:

>Translated_467_residues
MSVFPKDFLWGAATASYQVEGGFDADGKGLSNWDLFSHLPGTTYQGTNGDVAVDHYHRFREDVALMAELGMQTYRFSISW
PRLLPQGRGEVNEAGIQFYSDLIDELLKHNIKPMITLYHWDLPQALQEEFGGWESREIVDAFDEYARLCYQRFGDRVELW
STFNETIVFIGMGYITGAHPPKLTDPKKGIQACHHVFLANARAVKSFREMKINGQIGFVNVLQPNDPISDSPEDRRACEL
AEGIFTHWLYDPVLKGEYPAELLAMAQQAFGVPYFAPGDEALLKGNIVDFIGLNYYKREMVAHNDDVEGYAINTSGQKGS
GRELGFKGLFKLVRNPNGVYTDWDWEVYPQGLTDAIGRIVKRYGNIPIYITENGLGAKDPIVEGEVRDQPRIDYLRDHIQ
AIGAAIEQGADVRGYYPWSFIDLLSWLNGYQKQYGFVYVDHDNNLARKKKQSFGWYQRVIASHGEQL
>Mature_466_residues
SVFPKDFLWGAATASYQVEGGFDADGKGLSNWDLFSHLPGTTYQGTNGDVAVDHYHRFREDVALMAELGMQTYRFSISWP
RLLPQGRGEVNEAGIQFYSDLIDELLKHNIKPMITLYHWDLPQALQEEFGGWESREIVDAFDEYARLCYQRFGDRVELWS
TFNETIVFIGMGYITGAHPPKLTDPKKGIQACHHVFLANARAVKSFREMKINGQIGFVNVLQPNDPISDSPEDRRACELA
EGIFTHWLYDPVLKGEYPAELLAMAQQAFGVPYFAPGDEALLKGNIVDFIGLNYYKREMVAHNDDVEGYAINTSGQKGSG
RELGFKGLFKLVRNPNGVYTDWDWEVYPQGLTDAIGRIVKRYGNIPIYITENGLGAKDPIVEGEVRDQPRIDYLRDHIQA
IGAAIEQGADVRGYYPWSFIDLLSWLNGYQKQYGFVYVDHDNNLARKKKQSFGWYQRVIASHGEQL

Specific function: Is able to catalyze the hydrolysis of aryl-phospho-beta- D-glucosides such as 4-methylumbelliferyl-phospho-beta-D- glucopyranoside (MUG-P), phosphoarbutin and phosphosalicin. Is not essential for growth on arbutin and salicin as the sole carbon source [H]

COG id: COG2723

COG function: function code G; Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 1 family [H]

Homologues:

Organism=Homo sapiens, GI110681710, Length=481, Percent_Identity=36.7983367983368, Blast_Score=286, Evalue=2e-77,
Organism=Homo sapiens, GI32481206, Length=487, Percent_Identity=35.523613963039, Blast_Score=278, Evalue=7e-75,
Organism=Homo sapiens, GI13273313, Length=484, Percent_Identity=34.7107438016529, Blast_Score=267, Evalue=2e-71,
Organism=Homo sapiens, GI28376633, Length=477, Percent_Identity=30.398322851153, Blast_Score=206, Evalue=3e-53,
Organism=Homo sapiens, GI24497614, Length=491, Percent_Identity=30.7535641547862, Blast_Score=192, Evalue=5e-49,
Organism=Homo sapiens, GI190360571, Length=98, Percent_Identity=50, Blast_Score=97, Evalue=4e-20,
Organism=Escherichia coli, GI2367270, Length=490, Percent_Identity=36.3265306122449, Blast_Score=293, Evalue=2e-80,
Organism=Escherichia coli, GI1789070, Length=496, Percent_Identity=36.8951612903226, Blast_Score=285, Evalue=6e-78,
Organism=Escherichia coli, GI2367174, Length=500, Percent_Identity=35.6, Blast_Score=284, Evalue=7e-78,
Organism=Caenorhabditis elegans, GI17552856, Length=472, Percent_Identity=32.4152542372881, Blast_Score=251, Evalue=4e-67,
Organism=Caenorhabditis elegans, GI17539390, Length=486, Percent_Identity=31.6872427983539, Blast_Score=245, Evalue=3e-65,
Organism=Drosophila melanogaster, GI21356577, Length=468, Percent_Identity=36.1111111111111, Blast_Score=276, Evalue=3e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001360
- InterPro:   IPR018120
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00232 Glyco_hydro_1 [H]

EC number: =3.2.1.86 [H]

Molecular weight: Translated: 53057; Mature: 52926

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS00572 GLYCOSYL_HYDROL_F1_1 ; PS00653 GLYCOSYL_HYDROL_F1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVFPKDFLWGAATASYQVEGGFDADGKGLSNWDLFSHLPGTTYQGTNGDVAVDHYHRFR
CCCCCCHHHHCCCCCCEEECCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCEEHHHHHHHH
EDVALMAELGMQTYRFSISWPRLLPQGRGEVNEAGIQFYSDLIDELLKHNIKPMITLYHW
HHHHHHHHHCCHHEEEEECCHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEC
DLPQALQEEFGGWESREIVDAFDEYARLCYQRFGDRVELWSTFNETIVFIGMGYITGAHP
CCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEHHHHCCCEEEEEEEHHHCCCCC
PKLTDPKKGIQACHHVFLANARAVKSFREMKINGQIGFVNVLQPNDPISDSPEDRRACEL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEEEEECCCCCCCCCCHHHHHHHH
AEGIFTHWLYDPVLKGEYPAELLAMAQQAFGVPYFAPGDEALLKGNIVDFIGLNYYKREM
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCHHHHCCCCHHHHCCCHHHHHH
VAHNDDVEGYAINTSGQKGSGRELGFKGLFKLVRNPNGVYTDWDWEVYPQGLTDAIGRIV
HHCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCEECCCHHHHHHHHHH
KRYGNIPIYITENGLGAKDPIVEGEVRDQPRIDYLRDHIQAIGAAIEQGADVRGYYPWSF
HHHCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
IDLLSWLNGYQKQYGFVYVDHDNNLARKKKQSFGWYQRVIASHGEQL
HHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SVFPKDFLWGAATASYQVEGGFDADGKGLSNWDLFSHLPGTTYQGTNGDVAVDHYHRFR
CCCCCHHHHCCCCCCEEECCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCEEHHHHHHHH
EDVALMAELGMQTYRFSISWPRLLPQGRGEVNEAGIQFYSDLIDELLKHNIKPMITLYHW
HHHHHHHHHCCHHEEEEECCHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEEC
DLPQALQEEFGGWESREIVDAFDEYARLCYQRFGDRVELWSTFNETIVFIGMGYITGAHP
CCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEHHHHCCCEEEEEEEHHHCCCCC
PKLTDPKKGIQACHHVFLANARAVKSFREMKINGQIGFVNVLQPNDPISDSPEDRRACEL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEEEEECCCCCCCCCCHHHHHHHH
AEGIFTHWLYDPVLKGEYPAELLAMAQQAFGVPYFAPGDEALLKGNIVDFIGLNYYKREM
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCHHHHCCCCHHHHCCCHHHHHH
VAHNDDVEGYAINTSGQKGSGRELGFKGLFKLVRNPNGVYTDWDWEVYPQGLTDAIGRIV
HHCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCEECCCHHHHHHHHHH
KRYGNIPIYITENGLGAKDPIVEGEVRDQPRIDYLRDHIQAIGAAIEQGADVRGYYPWSF
HHHCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
IDLLSWLNGYQKQYGFVYVDHDNNLARKKKQSFGWYQRVIASHGEQL
HHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7704255; 8969502; 9384377; 2841296 [H]