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The map label for this gene is ssb [H]

Identifier: 157372339

GI number: 157372339

Start: 4559273

End: 4559818

Strand: Reverse

Name: ssb [H]

Synonym: Spro_4105

Alternate gene names: 157372339

Gene position: 4559818-4559273 (Counterclockwise)

Preceding gene: 157372340

Following gene: 157372338

Centisome position: 83.68

GC content: 53.85

Gene sequence:

>546_bases
ATGGCGTCTCGCGGCGTAAACAAAGTCATACTTGTCGGTCATCTCGGCCAAGATCCGGAAGTCCGTTACATGCCAAATGG
CGGTGCTGTTGCTAACATTACCCTGGCGACCTCAGAGAGCTGGCGCGATAAGGCGACCGGTGAGCAGAAAGAAAAAACCG
AATGGCACCGTGTCGTGCTGTTTGGCAAGCTTGCCGAAATTGCCGGTGAATATTTGCGTAAGGGCTCGCAGGTTTACATT
GAAGGCTTCCTGCAGACACGCAAATGGACCGATCAGGCCGGTGTGGAAAAATACACCACTGAAATCGTTGTTAACATTGG
CGGCACTCTGCAGATGTTGGGGGGACGTTCACAACCAGCCAACGCTGGACAACCTGGGCAGGGCAGTTGGGGAAAACCAC
AACAACCTTCACACAGCGGTACGCCGGCCCAGCAACCCCAGCAAGCTCAATCGGGTGGGAATGCCGCGCCGATGGATTTT
GACGATGACATACCTTTCCTTGGGTTTGGTTACGGTATCGCAAAATCAGCCATTTGCGCTCTGTGA

Upstream 100 bases:

>100_bases
AGCAACAGTATGCGGAAAACTCTTTCTGATAACGCCCTCTACGCCTCGGTTTTCGGGGCGTTTTTCCCTTTCTAATTCCA
TTCCCTATGAGGATTCGATT

Downstream 100 bases:

>100_bases
TTGTCGGGAGACATTATGCCGACAATTCTTAGAGTAGGTGGTTTTCGCTTTTACTTTTACAGTCATGAACCTAACGAACC
GGCGCATGTCCATATTGATA

Product: single-strand binding protein

Products: NA

Alternate protein names: SSB; Helix-destabilizing protein [H]

Number of amino acids: Translated: 181; Mature: 180

Protein sequence:

>181_residues
MASRGVNKVILVGHLGQDPEVRYMPNGGAVANITLATSESWRDKATGEQKEKTEWHRVVLFGKLAEIAGEYLRKGSQVYI
EGFLQTRKWTDQAGVEKYTTEIVVNIGGTLQMLGGRSQPANAGQPGQGSWGKPQQPSHSGTPAQQPQQAQSGGNAAPMDF
DDDIPFLGFGYGIAKSAICAL

Sequences:

>Translated_181_residues
MASRGVNKVILVGHLGQDPEVRYMPNGGAVANITLATSESWRDKATGEQKEKTEWHRVVLFGKLAEIAGEYLRKGSQVYI
EGFLQTRKWTDQAGVEKYTTEIVVNIGGTLQMLGGRSQPANAGQPGQGSWGKPQQPSHSGTPAQQPQQAQSGGNAAPMDF
DDDIPFLGFGYGIAKSAICAL
>Mature_180_residues
ASRGVNKVILVGHLGQDPEVRYMPNGGAVANITLATSESWRDKATGEQKEKTEWHRVVLFGKLAEIAGEYLRKGSQVYIE
GFLQTRKWTDQAGVEKYTTEIVVNIGGTLQMLGGRSQPANAGQPGQGSWGKPQQPSHSGTPAQQPQQAQSGGNAAPMDFD
DDIPFLGFGYGIAKSAICAL

Specific function: This protein is essential for replication of the chromosome. It is also involved in DNA recombination and repair [H]

COG id: COG0629

COG function: function code L; Single-stranded DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SSB domain [H]

Homologues:

Organism=Homo sapiens, GI4507231, Length=111, Percent_Identity=33.3333333333333, Blast_Score=72, Evalue=4e-13,
Organism=Escherichia coli, GI1790494, Length=178, Percent_Identity=67.4157303370787, Blast_Score=228, Evalue=2e-61,

Paralogues:

None

Copy number: 1622 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000424
- InterPro:   IPR011344 [H]

Pfam domain/function: PF00436 SSB [H]

EC number: NA

Molecular weight: Translated: 19402; Mature: 19271

Theoretical pI: Translated: 7.59; Mature: 7.59

Prosite motif: PS50935 SSB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASRGVNKVILVGHLGQDPEVRYMPNGGAVANITLATSESWRDKATGEQKEKTEWHRVVL
CCCCCCCEEEEEEECCCCCCEEECCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHH
FGKLAEIAGEYLRKGSQVYIEGFLQTRKWTDQAGVEKYTTEIVVNIGGTLQMLGGRSQPA
HHHHHHHHHHHHHCCCEEEEEEHHHHHCCCCCCCHHHEEEEEEEECCCEEEECCCCCCCC
NAGQPGQGSWGKPQQPSHSGTPAQQPQQAQSGGNAAPMDFDDDIPFLGFGYGIAKSAICA
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCEEEECHHHHHHHHHC
L
C
>Mature Secondary Structure 
ASRGVNKVILVGHLGQDPEVRYMPNGGAVANITLATSESWRDKATGEQKEKTEWHRVVL
CCCCCCEEEEEEECCCCCCEEECCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHH
FGKLAEIAGEYLRKGSQVYIEGFLQTRKWTDQAGVEKYTTEIVVNIGGTLQMLGGRSQPA
HHHHHHHHHHHHHCCCEEEEEEHHHHHCCCCCCCHHHEEEEEEEECCCEEEECCCCCCCC
NAGQPGQGSWGKPQQPSHSGTPAQQPQQAQSGGNAAPMDFDDDIPFLGFGYGIAKSAICA
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCEEEECHHHHHHHHHC
L
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12029035 [H]