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The map label for this gene is pgk [H]

Identifier: 157372179

GI number: 157372179

Start: 4369641

End: 4370801

Strand: Reverse

Name: pgk [H]

Synonym: Spro_3945

Alternate gene names: 157372179

Gene position: 4370801-4369641 (Counterclockwise)

Preceding gene: 157372180

Following gene: 157372178

Centisome position: 80.22

GC content: 53.4

Gene sequence:

>1161_bases
ATGTCTGTAATTAACATGTCCGATCTGGATCTGGCCGGTAAACGCGTTCTGATCCGCTCCGATCTGAACGTTCCAGTGAA
AGACGGTAAAGTGACTTCCGATGCACGTATCCGTGCCTCCCTGCCGACTATTGAAGCTGCGCTGAAACAAGGCGCCCGCG
TGATGGTAACTTCCCACCTGGGTCGTCCTACCGAAGGCGAGTACAACGAAGAATTCTCCCTGCTGCCTGTTGTTAACTAT
CTGAAAGAACACCTGAAAAACCCGGTTCGTCTGGCTAAAGACTACCTGGAAGGTGTTGACGTTGCAGAAGGTGAACTGGT
AGTGCTGGAAAACGTCCGTTTCAACAAGGGCGAGAAAAAAGACGACGAAACCCTTTCCAAAAAATATGCGGCGCTGTGCG
ACGTGTATGTGATGGACGCCTTCGGTACGGCACACCGTGCGCAGGCTTCCACCCACGGCGTGGGCAAGTTTGCACCTGTC
GCCTGTGCTGGCCCGCTGCTGTCTGCAGAACTGGAAGCCCTGGGCAAAGCGCTGAAAAGCCCGGCTCGCCCGATGGTTGC
CGTGGTTGGCGGTTCTAAGGTTTCGACTAAATTCGATGTGCTGAACTCGCTGGTGAAAATCGCCGATACGGTGATCGTGG
GCGGCGGTATCGCCAACACCTTCGTGGCTATCGATAACAACGTCGGTAAATCTCTGTACGAACCTGACTTCGTCGATGCA
GCGAGAAAACTGCGTGACGAGTTTAAAATTCCGGTTCCTACCGATTCTCGCGTAGGTACGGAGTTCTCTGAAACTGCACC
TGCCACCTTGAAAAAAGTCAGTGAAGTCAACGATGATGAAGAGATCATGGACTTCGGTGACGAAACCGCGCTGGCTATGG
CCAAGTTGCTCAAAGAAGCCAAAACCATTCTGTGGAATGGTCCGGTTGGCGTATTCGAGTTCCCTAACTTCCGTAAGGGT
ACCGAAATTGTCGCGCGCGCTATCGCAGACAGCGAGGCATTCTCTATCGCTGGTGGTGGTGATACGCTGGCGGCTATCGA
TCTGTTCGGTATCGAGGATAAGATTTCCTACATCTCTACCGGCGGCGGCGCCTTCCTGGAATTCGTGGAAGGCAAAGCGT
TACCGGCAGTTGTGATGCTGGAAGAGCGCGCTAAGCAGTAA

Upstream 100 bases:

>100_bases
CAATGGCCGCAAGCGGTTTCTAGTACGGCGGCATCGGCACGACCGATGCGCCGCTCAGGCAACTTTATAGTTTCTAGAGA
ATCAACCAAGAGGGTTCACC

Downstream 100 bases:

>100_bases
TTCAGACAACGGGAGGCGAAAGTCGCCCGTTTATTTTATACCGCGCGGCATAGGCGGCGCGGCATGAAAAATCGATTTAC
ATCCATCTACGGCCGACGAA

Product: phosphoglycerate kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 386; Mature: 385

Protein sequence:

>386_residues
MSVINMSDLDLAGKRVLIRSDLNVPVKDGKVTSDARIRASLPTIEAALKQGARVMVTSHLGRPTEGEYNEEFSLLPVVNY
LKEHLKNPVRLAKDYLEGVDVAEGELVVLENVRFNKGEKKDDETLSKKYAALCDVYVMDAFGTAHRAQASTHGVGKFAPV
ACAGPLLSAELEALGKALKSPARPMVAVVGGSKVSTKFDVLNSLVKIADTVIVGGGIANTFVAIDNNVGKSLYEPDFVDA
ARKLRDEFKIPVPTDSRVGTEFSETAPATLKKVSEVNDDEEIMDFGDETALAMAKLLKEAKTILWNGPVGVFEFPNFRKG
TEIVARAIADSEAFSIAGGGDTLAAIDLFGIEDKISYISTGGGAFLEFVEGKALPAVVMLEERAKQ

Sequences:

>Translated_386_residues
MSVINMSDLDLAGKRVLIRSDLNVPVKDGKVTSDARIRASLPTIEAALKQGARVMVTSHLGRPTEGEYNEEFSLLPVVNY
LKEHLKNPVRLAKDYLEGVDVAEGELVVLENVRFNKGEKKDDETLSKKYAALCDVYVMDAFGTAHRAQASTHGVGKFAPV
ACAGPLLSAELEALGKALKSPARPMVAVVGGSKVSTKFDVLNSLVKIADTVIVGGGIANTFVAIDNNVGKSLYEPDFVDA
ARKLRDEFKIPVPTDSRVGTEFSETAPATLKKVSEVNDDEEIMDFGDETALAMAKLLKEAKTILWNGPVGVFEFPNFRKG
TEIVARAIADSEAFSIAGGGDTLAAIDLFGIEDKISYISTGGGAFLEFVEGKALPAVVMLEERAKQ
>Mature_385_residues
SVINMSDLDLAGKRVLIRSDLNVPVKDGKVTSDARIRASLPTIEAALKQGARVMVTSHLGRPTEGEYNEEFSLLPVVNYL
KEHLKNPVRLAKDYLEGVDVAEGELVVLENVRFNKGEKKDDETLSKKYAALCDVYVMDAFGTAHRAQASTHGVGKFAPVA
CAGPLLSAELEALGKALKSPARPMVAVVGGSKVSTKFDVLNSLVKIADTVIVGGGIANTFVAIDNNVGKSLYEPDFVDAA
RKLRDEFKIPVPTDSRVGTEFSETAPATLKKVSEVNDDEEIMDFGDETALAMAKLLKEAKTILWNGPVGVFEFPNFRKGT
EIVARAIADSEAFSIAGGGDTLAAIDLFGIEDKISYISTGGGAFLEFVEGKALPAVVMLEERAKQ

Specific function: Second phase of glycolysis; second step. [C]

COG id: COG0126

COG function: function code G; 3-phosphoglycerate kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate kinase family [H]

Homologues:

Organism=Homo sapiens, GI31543397, Length=408, Percent_Identity=36.5196078431373, Blast_Score=239, Evalue=3e-63,
Organism=Homo sapiens, GI4505763, Length=408, Percent_Identity=37.2549019607843, Blast_Score=239, Evalue=3e-63,
Organism=Escherichia coli, GI1789294, Length=387, Percent_Identity=83.4625322997416, Blast_Score=651, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17508823, Length=414, Percent_Identity=40.5797101449275, Blast_Score=256, Evalue=1e-68,
Organism=Saccharomyces cerevisiae, GI6319857, Length=419, Percent_Identity=39.1408114558473, Blast_Score=251, Evalue=1e-67,
Organism=Drosophila melanogaster, GI17136394, Length=410, Percent_Identity=39.2682926829268, Blast_Score=243, Evalue=1e-64,
Organism=Drosophila melanogaster, GI24581203, Length=416, Percent_Identity=37.2596153846154, Blast_Score=235, Evalue=4e-62,

Paralogues:

None

Copy number: 2990 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1460 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001576
- InterPro:   IPR015901
- InterPro:   IPR015911
- InterPro:   IPR015824 [H]

Pfam domain/function: PF00162 PGK [H]

EC number: =2.7.2.3 [H]

Molecular weight: Translated: 41394; Mature: 41263

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS00111 PGLYCERATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVINMSDLDLAGKRVLIRSDLNVPVKDGKVTSDARIRASLPTIEAALKQGARVMVTSHL
CCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCEEEECCHHHHHHHHCCCEEEEEECC
GRPTEGEYNEEFSLLPVVNYLKEHLKNPVRLAKDYLEGVDVAEGELVVLENVRFNKGEKK
CCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCC
DDETLSKKYAALCDVYVMDAFGTAHRAQASTHGVGKFAPVACAGPLLSAELEALGKALKS
CHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCHHHCCHHHHHHHHHHHHHHCC
PARPMVAVVGGSKVSTKFDVLNSLVKIADTVIVGGGIANTFVAIDNNVGKSLYEPDFVDA
CCCCEEEEECCCCCHHHHHHHHHHHHHHHHHEECCCHHEEEEEEECCCCCCCCCCHHHHH
ARKLRDEFKIPVPTDSRVGTEFSETAPATLKKVSEVNDDEEIMDFGDETALAMAKLLKEA
HHHHHHHCCCCCCCCCCCCCCHHHCCHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHH
KTILWNGPVGVFEFPNFRKGTEIVARAIADSEAFSIAGGGDTLAAIDLFGIEDKISYIST
HHEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCEEEEEEECCHHHHHEEEC
GGGAFLEFVEGKALPAVVMLEERAKQ
CCHHHHHHHCCCCCCHHEEEHHHHCC
>Mature Secondary Structure 
SVINMSDLDLAGKRVLIRSDLNVPVKDGKVTSDARIRASLPTIEAALKQGARVMVTSHL
CCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCEEEECCHHHHHHHHCCCEEEEEECC
GRPTEGEYNEEFSLLPVVNYLKEHLKNPVRLAKDYLEGVDVAEGELVVLENVRFNKGEKK
CCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCC
DDETLSKKYAALCDVYVMDAFGTAHRAQASTHGVGKFAPVACAGPLLSAELEALGKALKS
CHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCCCCHHHCCHHHHHHHHHHHHHHCC
PARPMVAVVGGSKVSTKFDVLNSLVKIADTVIVGGGIANTFVAIDNNVGKSLYEPDFVDA
CCCCEEEEECCCCCHHHHHHHHHHHHHHHHHEECCCHHEEEEEEECCCCCCCCCCHHHHH
ARKLRDEFKIPVPTDSRVGTEFSETAPATLKKVSEVNDDEEIMDFGDETALAMAKLLKEA
HHHHHHHCCCCCCCCCCCCCCHHHCCHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHHH
KTILWNGPVGVFEFPNFRKGTEIVARAIADSEAFSIAGGGDTLAAIDLFGIEDKISYIST
HHEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCEEEEEEECCHHHHHEEEC
GGGAFLEFVEGKALPAVVMLEERAKQ
CCHHHHHHHCCCCCCHHEEEHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA