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The map label for this gene is argO

Identifier: 157372161

GI number: 157372161

Start: 4350785

End: 4351402

Strand: Reverse

Name: argO

Synonym: Spro_3927

Alternate gene names: 157372161

Gene position: 4351402-4350785 (Counterclockwise)

Preceding gene: 157372162

Following gene: 157372160

Centisome position: 79.86

GC content: 60.03

Gene sequence:

>618_bases
ATGCTAGCTGTCTTTTTGCAGGGCTTTGCCCTGAGCGCCGCGATGATCCTGCCGCTTGGCCCACAAAACGTTTTTGTTAT
GAATCAGGGTATTCGTCGCCAGTATCATCTGATGGTCGCGTCGTTGTGTGCGCTGAGCGACATCGTGCTGATCTGCGGCG
GGATTTTCGGTGGCAGCGCCTTACTGAGCCGCTCGCCGCTACTGCTGGCGCTGGTGACCTGGGGTGGGGTAGCTTTCCTG
CTGTGGTACGGCTGGGGGGCCTTTCGTACCGCATTTAGCCGGCAACTGGCGTTGGCGACGGCCGAAGAGCTGAAGCAAAG
CCGCTGGCGGCTGGTGGTTACCATGCTGGCGGTGACCTGGCTGAACCCGCATGTCTATCTCGACACCTTTGTGGTGCTGG
GAAGTTTGGGGGGGCAACTGACGCCGGATGTACGTTCCTGGTTTGCGCTGGGGGCGGTGAGCGCTTCCGTCGTGTGGTTC
TTCGCCCTGGCACTGTTGGCCTCCTGGCTGGCGCCGTGGCTGAAAACCCAAATGGCGCAGCGCATCATTAATACATTGGT
CGGGGTGGTGATGTGGGGCATCGCCTTGCAGTTGGCCTGGCAAGGGGCAAGTTTATAA

Upstream 100 bases:

>100_bases
TTAGAAATATCAATTTCACCTAATAATTTTTTCCTCCTATGATGCGCGTATTGACCGATACGCGCCGCTGAACGGCGCTC
TTTTCTCTGTGAGGAATACC

Downstream 100 bases:

>100_bases
GAATTTGTCACTAATCCGAATTCAAAAACCCGTGCGATATGCTAGCTTTGATGCCAAGGAACTGGCCTTTCAGGCCGGTA
ATCAGTTAGAGCCTGTCATC

Product: arginine exporter protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 205; Mature: 205

Protein sequence:

>205_residues
MLAVFLQGFALSAAMILPLGPQNVFVMNQGIRRQYHLMVASLCALSDIVLICGGIFGGSALLSRSPLLLALVTWGGVAFL
LWYGWGAFRTAFSRQLALATAEELKQSRWRLVVTMLAVTWLNPHVYLDTFVVLGSLGGQLTPDVRSWFALGAVSASVVWF
FALALLASWLAPWLKTQMAQRIINTLVGVVMWGIALQLAWQGASL

Sequences:

>Translated_205_residues
MLAVFLQGFALSAAMILPLGPQNVFVMNQGIRRQYHLMVASLCALSDIVLICGGIFGGSALLSRSPLLLALVTWGGVAFL
LWYGWGAFRTAFSRQLALATAEELKQSRWRLVVTMLAVTWLNPHVYLDTFVVLGSLGGQLTPDVRSWFALGAVSASVVWF
FALALLASWLAPWLKTQMAQRIINTLVGVVMWGIALQLAWQGASL
>Mature_205_residues
MLAVFLQGFALSAAMILPLGPQNVFVMNQGIRRQYHLMVASLCALSDIVLICGGIFGGSALLSRSPLLLALVTWGGVAFL
LWYGWGAFRTAFSRQLALATAEELKQSRWRLVVTMLAVTWLNPHVYLDTFVVLGSLGGQLTPDVRSWFALGAVSASVVWF
FALALLASWLAPWLKTQMAQRIINTLVGVVMWGIALQLAWQGASL

Specific function: Involved in the export of arginine. Important to control the intracellular level of arginine and the correct balance between arginine and lysine

COG id: COG1279

COG function: function code R; Lysine efflux permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LysE/ArgO transporter (TC 2.A.75) family

Homologues:

Organism=Escherichia coli, GI1789290, Length=202, Percent_Identity=73.2673267326733, Blast_Score=282, Evalue=1e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGO_SERP5 (A8GIT2)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001480150.1
- STRING:   A8GIT2
- GeneID:   5604164
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_3927
- eggNOG:   COG1279
- HOGENOM:   HBG683136
- OMA:   EHHLPVA
- ProtClustDB:   PRK09304
- BioCyc:   SPRO399741:SPRO_3927-MONOMER
- HAMAP:   MF_01901
- InterPro:   IPR004777
- InterPro:   IPR001123
- TIGRFAMs:   TIGR00948

Pfam domain/function: PF01810 LysE

EC number: NA

Molecular weight: Translated: 22367; Mature: 22367

Theoretical pI: Translated: 10.55; Mature: 10.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xee3beb4)-; HASH(0x1145c7f0)-; HASH(0x1106be38)-; HASH(0x10e7c508)-; HASH(0x109c97c8)-; HASH(0x106c1314)-;

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAVFLQGFALSAAMILPLGPQNVFVMNQGIRRQYHLMVASLCALSDIVLICGGIFGGSA
CHHHHHHHHHHHHHHEEECCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
LLSRSPLLLALVTWGGVAFLLWYGWGAFRTAFSRQLALATAEELKQSRWRLVVTMLAVTW
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNPHVYLDTFVVLGSLGGQLTPDVRSWFALGAVSASVVWFFALALLASWLAPWLKTQMAQ
CCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RIINTLVGVVMWGIALQLAWQGASL
HHHHHHHHHHHHHHHHHHHHCCCCH
>Mature Secondary Structure
MLAVFLQGFALSAAMILPLGPQNVFVMNQGIRRQYHLMVASLCALSDIVLICGGIFGGSA
CHHHHHHHHHHHHHHEEECCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
LLSRSPLLLALVTWGGVAFLLWYGWGAFRTAFSRQLALATAEELKQSRWRLVVTMLAVTW
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNPHVYLDTFVVLGSLGGQLTPDVRSWFALGAVSASVVWFFALALLASWLAPWLKTQMAQ
CCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RIINTLVGVVMWGIALQLAWQGASL
HHHHHHHHHHHHHHHHHHHHCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA