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The map label for this gene is agaR [H]

Identifier: 157372084

GI number: 157372084

Start: 4259199

End: 4259972

Strand: Reverse

Name: agaR [H]

Synonym: Spro_3849

Alternate gene names: 157372084

Gene position: 4259972-4259199 (Counterclockwise)

Preceding gene: 157372086

Following gene: 157372083

Centisome position: 78.18

GC content: 58.01

Gene sequence:

>774_bases
ATGCCAGTGAATACCGCAAAGCGACGTGAACACATTATCGACTTGTTATGCGAGCACGGTAGCGTGCGCGTGGAGCAGCT
CAGCAAACAGTTTGCAGTATCCACGGTGACGATCCGCAACGATCTGCGCTTTCTGGAACGAAAAGGGTGTGCGCTGCGGG
CTTATGGCGGCGCGATGCTCAATCAGCAATTCGCCTTCGATCGCCCGTTGCATGACAAAGGGCGGTTAAACCGCGACGTG
AAGTCGCAGATCGCAAGCGTAGCGGCCAGCTATGTGCGCGATGGTGACGCGCTGATCCTCGATTCCGGTTCCACCACTAC
CCAGATAGTGCCGTTCCTCAAAGGGCGACGCGATCTGGTGGTGATGACCAATGCGCTGAACATTGCCTATGAGCTTTCAG
GTAACGATGGGGTGGAGGTGATGGTGCTGGGGGGCAGCGTGCGCCGTAACTCCTACTCGCTCTACGGTCCGGCTGCCGAG
CAGCAATTGCGCCAGTACCGCTTTGACAAACTGTTTTTGGGTGTCGACGGTTTCGATCTGGTTGCCGGCATCACCACGCC
TCACCCCGGTGAGGCCCACCTCAATCGCGTGATGTGCGAGGTGGCGCGCGAGATCATCGCCGTGGCGGATGCCAGCAAGT
TTGGTCGCAAGAGCTTTTGCATGATTCGCGAAGCCGGACAAATTCATCGGCTGATTACCGACAGCCTTCTTCCGGACGAT
TACGAGCGGGCGTTAACCGAGTTGGGCGTGGAGGTTGTCATCGCCGATCGGTAG

Upstream 100 bases:

>100_bases
CGATCACAATTTCATTGCTTTCGCTTTGCTGTAATGCCAGCGCAGTAGAGCGAAAGCCATCTTCTCCCCGGCCCGGCCGG
AAACCTGAGGACCGCAGCTC

Downstream 100 bases:

>100_bases
TACGGCGCCTGCGTGGGGGTTTCATGCAGCAGTTGTTACAGCTTGTTGAGCAGCACAAGGCCGGAAAACCGGTTGGGGTA
TTTTCCGTTTGTTCCGCTCA

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 256

Protein sequence:

>257_residues
MPVNTAKRREHIIDLLCEHGSVRVEQLSKQFAVSTVTIRNDLRFLERKGCALRAYGGAMLNQQFAFDRPLHDKGRLNRDV
KSQIASVAASYVRDGDALILDSGSTTTQIVPFLKGRRDLVVMTNALNIAYELSGNDGVEVMVLGGSVRRNSYSLYGPAAE
QQLRQYRFDKLFLGVDGFDLVAGITTPHPGEAHLNRVMCEVAREIIAVADASKFGRKSFCMIREAGQIHRLITDSLLPDD
YERALTELGVEVVIADR

Sequences:

>Translated_257_residues
MPVNTAKRREHIIDLLCEHGSVRVEQLSKQFAVSTVTIRNDLRFLERKGCALRAYGGAMLNQQFAFDRPLHDKGRLNRDV
KSQIASVAASYVRDGDALILDSGSTTTQIVPFLKGRRDLVVMTNALNIAYELSGNDGVEVMVLGGSVRRNSYSLYGPAAE
QQLRQYRFDKLFLGVDGFDLVAGITTPHPGEAHLNRVMCEVAREIIAVADASKFGRKSFCMIREAGQIHRLITDSLLPDD
YERALTELGVEVVIADR
>Mature_256_residues
PVNTAKRREHIIDLLCEHGSVRVEQLSKQFAVSTVTIRNDLRFLERKGCALRAYGGAMLNQQFAFDRPLHDKGRLNRDVK
SQIASVAASYVRDGDALILDSGSTTTQIVPFLKGRRDLVVMTNALNIAYELSGNDGVEVMVLGGSVRRNSYSLYGPAAEQ
QLRQYRFDKLFLGVDGFDLVAGITTPHPGEAHLNRVMCEVAREIIAVADASKFGRKSFCMIREAGQIHRLITDSLLPDDY
ERALTELGVEVVIADR

Specific function: Probable repressor for the aga operon for N-acetyl galactosamine transport and metabolism [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789519, Length=252, Percent_Identity=45.6349206349206, Blast_Score=216, Evalue=1e-57,
Organism=Escherichia coli, GI1789059, Length=251, Percent_Identity=40.2390438247012, Blast_Score=187, Evalue=5e-49,
Organism=Escherichia coli, GI226510968, Length=249, Percent_Identity=30.9236947791165, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1789829, Length=247, Percent_Identity=28.7449392712551, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI1788069, Length=229, Percent_Identity=29.6943231441048, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI87082344, Length=252, Percent_Identity=27.7777777777778, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1787540, Length=230, Percent_Identity=30.4347826086957, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI1790753, Length=251, Percent_Identity=26.2948207171315, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1789170, Length=231, Percent_Identity=27.2727272727273, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1790635, Length=254, Percent_Identity=25.5905511811024, Blast_Score=72, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 28538; Mature: 28407

Theoretical pI: Translated: 7.98; Mature: 7.98

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2 ; PS00141 ASP_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVNTAKRREHIIDLLCEHGSVRVEQLSKQFAVSTVTIRNDLRFLERKGCALRAYGGAML
CCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHEEEEEHHHHHHHHHCCCEEEECCCHHH
NQQFAFDRPLHDKGRLNRDVKSQIASVAASYVRDGDALILDSGSTTTQIVPFLKGRRDLV
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHCCCCEEE
VMTNALNIAYELSGNDGVEVMVLGGSVRRNSYSLYGPAAEQQLRQYRFDKLFLGVDGFDL
EEEEEEEEEEEECCCCCEEEEEECCCCCCCCEEEECCHHHHHHHHHHHHHEEECCCCHHH
VAGITTPHPGEAHLNRVMCEVAREIIAVADASKFGRKSFCMIREAGQIHRLITDSLLPDD
HEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCH
YERALTELGVEVVIADR
HHHHHHHCCEEEEEECC
>Mature Secondary Structure 
PVNTAKRREHIIDLLCEHGSVRVEQLSKQFAVSTVTIRNDLRFLERKGCALRAYGGAML
CCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHEEEEEHHHHHHHHHCCCEEEECCCHHH
NQQFAFDRPLHDKGRLNRDVKSQIASVAASYVRDGDALILDSGSTTTQIVPFLKGRRDLV
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHCCCCEEE
VMTNALNIAYELSGNDGVEVMVLGGSVRRNSYSLYGPAAEQQLRQYRFDKLFLGVDGFDL
EEEEEEEEEEEECCCCCEEEEEECCCCCCCCEEEECCHHHHHHHHHHHHHEEECCCCHHH
VAGITTPHPGEAHLNRVMCEVAREIIAVADASKFGRKSFCMIREAGQIHRLITDSLLPDD
HEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCH
YERALTELGVEVVIADR
HHHHHHHCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]