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The map label for this gene is cadC [H]

Identifier: 157372004

GI number: 157372004

Start: 4165625

End: 4167181

Strand: Reverse

Name: cadC [H]

Synonym: Spro_3769

Alternate gene names: 157372004

Gene position: 4167181-4165625 (Counterclockwise)

Preceding gene: 157372005

Following gene: 157372003

Centisome position: 76.48

GC content: 51.51

Gene sequence:

>1557_bases
ATGCAAGAACCCGTTTTTCGCGTTGGTGAGTGGTTGGTTACTCCCGCAGACAACAAAATAAGCCGTGATGGGCGCCAACT
GGCGTTGGAGCCGCGCTTAATCGATATGCTGCAATATTTCGCCCGGCACCCGGATGTGGTGCTGAGTCGCGATGAGCTGA
TCGATAACGTTTGGAAGCGCAACATTGTCACCAACCATGTGGTGACTCAGAGTATTTCCGAACTGCGCAAATACCTGAAG
GACGGTGACAGCAACAGCCCGGAATACATCATTACCGTGCCCAAGCGCGGCTATAAGCTGGCTGCGCCAGTGATGTGGTG
TGAAGGGGAAGAGACAGGCATACCTGCGCTACCGCGGGTGGCGGTCATCACCCATGAGCCGGAAGATGGCAGTGAAGACG
ATGACGTTGATTATCAACCGCCAAAACCCAGCCAGGCAAAAACATCGCCGGCAAAGTCGAAGGTGGCTTTTTATCGACAA
TCACCGTTCTGGGTGTGGCTGGCTTTCCTGGCGGCATTGAGCGCCTGCGTGGTGTTTGTGGCCATTGCAACTTTGTCGCG
TCGCATACCGGAATCCACCATGCCGGTGCTGATGAACCCGCGGGATATTGATATCCGCATTCAGGGGGGCAACAGCTGCA
GTAACTGGACGCCGCAACTTTCCTATGTCGTCGGCCTGAGCGAAGTAGTCACGGACTCGCTAAATACCTATTCCACTTTC
CTGGTGCACGATCAAACCAACTATAACTACACCGGACCAAGCAGTTCGGGTAAATCGCTGACCATTGAGTTCGTCAACCA
GCGCCATTATCGTGCGCAGCAATGTTTCCTGTCGGTACGGCTGGTGGACAATGCGGACAGCTCGATCATGCTGGATAAGC
GCTACTTCGTTACTACAGACAATCAACTGAAAATTCAAGAGGACTTCCTGAGTAGCCTGTCTTTGGCCCTCAATCAGCCG
TGGCCGGCCCCTTTGCAGCAGCGGTTGATGAAACTCTTGCCAAACTCAGGCCCGGAACTGCAGCAGTATTACCAGGCACA
TCAGTTATTGATCCAGGGGGATATCGATTCTTTGACCCATGCCAGTCGCATGCTGGGTGATATGGTGAAATCGTCTCCGG
ACTTTATTTATATTGCAGCCGAAAAAGCGCTGGCAGACTTACTGCGTAATTCTTATCAACCTTTTGATACTGTGCAGTTG
GCACAACTGGATACGGAGATAGCTCGCCTGGATGCGCTGCCCGCTTTAAAAGACAGCCCCATAATTCAGCAAATTCATAC
GATACGGGCACTGGGAGAGGGGAAAACCGATGAGGCTTATCAGGCGATAAATAAAGGCATCGAGCTGCAGATGTCATGGA
TGAATTATGTGTTGCTCGGTAAAGTTTATGAAATGCAGGGCTACAATCGCTTGGCTGCAGATTCCTATATCACGGCATTT
AACCTGCGTCCGGGCGAGAATACCCTGCACTGGATCCGTAATGCCGTCTTCCATACCTCAATAAACACCGTAGTTCCCTA
CCTCGAAAACTACAATCCGGATAAACAACCCAATTAA

Upstream 100 bases:

>100_bases
TATGAGGTATGAATGCTTAATCGGGGCATATCGACGCAGGTCGGGCGCTCATATGGTATTATCCCGCGCTTGCCGCACCC
CCTTTTGAGTTATTTTCACT

Downstream 100 bases:

>100_bases
GCCACGCCGCCGAGTCAGATAGTTGACCGGCGGTGTTATTTATTGTGTTTTATTTGTTAAGCCCCATTAACTTATTGGTT
GATTTATTTTTCTCTTTTAT

Product: DNA-binding transcriptional activator CadC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 518; Mature: 518

Protein sequence:

>518_residues
MQEPVFRVGEWLVTPADNKISRDGRQLALEPRLIDMLQYFARHPDVVLSRDELIDNVWKRNIVTNHVVTQSISELRKYLK
DGDSNSPEYIITVPKRGYKLAAPVMWCEGEETGIPALPRVAVITHEPEDGSEDDDVDYQPPKPSQAKTSPAKSKVAFYRQ
SPFWVWLAFLAALSACVVFVAIATLSRRIPESTMPVLMNPRDIDIRIQGGNSCSNWTPQLSYVVGLSEVVTDSLNTYSTF
LVHDQTNYNYTGPSSSGKSLTIEFVNQRHYRAQQCFLSVRLVDNADSSIMLDKRYFVTTDNQLKIQEDFLSSLSLALNQP
WPAPLQQRLMKLLPNSGPELQQYYQAHQLLIQGDIDSLTHASRMLGDMVKSSPDFIYIAAEKALADLLRNSYQPFDTVQL
AQLDTEIARLDALPALKDSPIIQQIHTIRALGEGKTDEAYQAINKGIELQMSWMNYVLLGKVYEMQGYNRLAADSYITAF
NLRPGENTLHWIRNAVFHTSINTVVPYLENYNPDKQPN

Sequences:

>Translated_518_residues
MQEPVFRVGEWLVTPADNKISRDGRQLALEPRLIDMLQYFARHPDVVLSRDELIDNVWKRNIVTNHVVTQSISELRKYLK
DGDSNSPEYIITVPKRGYKLAAPVMWCEGEETGIPALPRVAVITHEPEDGSEDDDVDYQPPKPSQAKTSPAKSKVAFYRQ
SPFWVWLAFLAALSACVVFVAIATLSRRIPESTMPVLMNPRDIDIRIQGGNSCSNWTPQLSYVVGLSEVVTDSLNTYSTF
LVHDQTNYNYTGPSSSGKSLTIEFVNQRHYRAQQCFLSVRLVDNADSSIMLDKRYFVTTDNQLKIQEDFLSSLSLALNQP
WPAPLQQRLMKLLPNSGPELQQYYQAHQLLIQGDIDSLTHASRMLGDMVKSSPDFIYIAAEKALADLLRNSYQPFDTVQL
AQLDTEIARLDALPALKDSPIIQQIHTIRALGEGKTDEAYQAINKGIELQMSWMNYVLLGKVYEMQGYNRLAADSYITAF
NLRPGENTLHWIRNAVFHTSINTVVPYLENYNPDKQPN
>Mature_518_residues
MQEPVFRVGEWLVTPADNKISRDGRQLALEPRLIDMLQYFARHPDVVLSRDELIDNVWKRNIVTNHVVTQSISELRKYLK
DGDSNSPEYIITVPKRGYKLAAPVMWCEGEETGIPALPRVAVITHEPEDGSEDDDVDYQPPKPSQAKTSPAKSKVAFYRQ
SPFWVWLAFLAALSACVVFVAIATLSRRIPESTMPVLMNPRDIDIRIQGGNSCSNWTPQLSYVVGLSEVVTDSLNTYSTF
LVHDQTNYNYTGPSSSGKSLTIEFVNQRHYRAQQCFLSVRLVDNADSSIMLDKRYFVTTDNQLKIQEDFLSSLSLALNQP
WPAPLQQRLMKLLPNSGPELQQYYQAHQLLIQGDIDSLTHASRMLGDMVKSSPDFIYIAAEKALADLLRNSYQPFDTVQL
AQLDTEIARLDALPALKDSPIIQQIHTIRALGEGKTDEAYQAINKGIELQMSWMNYVLLGKVYEMQGYNRLAADSYITAF
NLRPGENTLHWIRNAVFHTSINTVVPYLENYNPDKQPN

Specific function: Required for Pcad induction, a promoter upstream of cadB that is responsible for the pH-regulated expression of cadA [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790576, Length=519, Percent_Identity=58.5741811175337, Blast_Score=583, Evalue=1e-168,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR011990
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 58677; Mature: 58677

Theoretical pI: Translated: 5.48; Mature: 5.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQEPVFRVGEWLVTPADNKISRDGRQLALEPRLIDMLQYFARHPDVVLSRDELIDNVWKR
CCCCHHHHCCEEECCCCCCCCCCCCEEEECHHHHHHHHHHHCCCCEEECHHHHHHHHHHH
NIVTNHVVTQSISELRKYLKDGDSNSPEYIITVPKRGYKLAAPVMWCEGEETGIPALPRV
HHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCEEECCEEEECCCCCCCCCCCEE
AVITHEPEDGSEDDDVDYQPPKPSQAKTSPAKSKVAFYRQSPFWVWLAFLAALSACVVFV
EEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHEEEEECCCHHHHHHHHHHHHHHHHHH
AIATLSRRIPESTMPVLMNPRDIDIRIQGGNSCSNWTPQLSYVVGLSEVVTDSLNTYSTF
HHHHHHHHCCCCCCCEEECCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEE
LVHDQTNYNYTGPSSSGKSLTIEFVNQRHYRAQQCFLSVRLVDNADSSIMLDKRYFVTTD
EEECCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHEEEEEEECCCCCCEEEECEEEEECC
NQLKIQEDFLSSLSLALNQPWPAPLQQRLMKLLPNSGPELQQYYQAHQLLIQGDIDSLTH
CCEEEHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHEEEECCHHHHHH
ASRMLGDMVKSSPDFIYIAAEKALADLLRNSYQPFDTVQLAQLDTEIARLDALPALKDSP
HHHHHHHHHHCCCCEEEEEHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCH
IIQQIHTIRALGEGKTDEAYQAINKGIELQMSWMNYVLLGKVYEMQGYNRLAADSYITAF
HHHHHHHHHHHCCCCCHHHHHHHHCCCEEEEHHHHHHHHHHHHHHCCCCCHHCCCEEEEE
NLRPGENTLHWIRNAVFHTSINTVVPYLENYNPDKQPN
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MQEPVFRVGEWLVTPADNKISRDGRQLALEPRLIDMLQYFARHPDVVLSRDELIDNVWKR
CCCCHHHHCCEEECCCCCCCCCCCCEEEECHHHHHHHHHHHCCCCEEECHHHHHHHHHHH
NIVTNHVVTQSISELRKYLKDGDSNSPEYIITVPKRGYKLAAPVMWCEGEETGIPALPRV
HHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCEEECCEEEECCCCCCCCCCCEE
AVITHEPEDGSEDDDVDYQPPKPSQAKTSPAKSKVAFYRQSPFWVWLAFLAALSACVVFV
EEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHEEEEECCCHHHHHHHHHHHHHHHHHH
AIATLSRRIPESTMPVLMNPRDIDIRIQGGNSCSNWTPQLSYVVGLSEVVTDSLNTYSTF
HHHHHHHHCCCCCCCEEECCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEE
LVHDQTNYNYTGPSSSGKSLTIEFVNQRHYRAQQCFLSVRLVDNADSSIMLDKRYFVTTD
EEECCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHEEEEEEECCCCCCEEEECEEEEECC
NQLKIQEDFLSSLSLALNQPWPAPLQQRLMKLLPNSGPELQQYYQAHQLLIQGDIDSLTH
CCEEEHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHEEEECCHHHHHH
ASRMLGDMVKSSPDFIYIAAEKALADLLRNSYQPFDTVQLAQLDTEIARLDALPALKDSP
HHHHHHHHHHCCCCEEEEEHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCH
IIQQIHTIRALGEGKTDEAYQAINKGIELQMSWMNYVLLGKVYEMQGYNRLAADSYITAF
HHHHHHHHHHHCCCCCHHHHHHHHCCCEEEEHHHHHHHHHHHHHHCCCCCHHCCCEEEEE
NLRPGENTLHWIRNAVFHTSINTVVPYLENYNPDKQPN
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1370290; 7610040; 9278503 [H]