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The map label for this gene is irgA [H]

Identifier: 157371731

GI number: 157371731

Start: 3869115

End: 3871262

Strand: Reverse

Name: irgA [H]

Synonym: Spro_3494

Alternate gene names: 157371731

Gene position: 3871262-3869115 (Counterclockwise)

Preceding gene: 157371736

Following gene: 157371728

Centisome position: 71.05

GC content: 53.12

Gene sequence:

>2148_bases
ATGTGCGCAGTGGGCAGGTATTGGCCACTCACTTCTTGTTACGCCGCCGTTTTTGGATGCTTTGCGGGCTACAACACCAA
TCGGAAACAGGTTTTATTAGGAATAGTTATGATTGATCAACACTTCATGGGAAAACGCAGCCAAATAGCCAGAGCAATGG
CGCTGGTATTGATTATTGCCCCTCAGGCTTATGCGCAGGAAGGGGAGGCAGAGCAGAAAAATAACGCCTCGCAGGAAGAC
CAACTGGTGGTCACCGCTTCCGGATTCAAGCAGAACAAGAAATATGCCCCGGCCAGCATTTCGGTTATCGATCAAAAGAC
GCTCGAGAAGCAGAACAGCCACGATGTGGCCGAAGCGGTTCAGGATATTTCTGGCGTGTCGGTCAGCAATGGTGCCGGCA
CTGAGGTTTCCGGCGACGTTATGATCCGCGGTATGGACTCGAGTTACACCTCGTTCATGGTCAACAGCATCAAGCAGAAT
ACCGGCGAATCCCGTCCCTATGGCCAGAATGTCGGCACTGAAGCCGGCTTTTTACCGCCGGTGGCGGCCATCGATCGTAT
TGAGGTGATCCGTGGCCCGATGTCATCGCTGTACGGCTCGGACTCCATCGGCGGCGTGGTCAACGTCATTACCAAAAAGC
CGTTTGGCGTACGAGAATGGATGGGCTCGATCGCGGCAAACAGTTTCCTGCAACAACATCAGGAGTTCGGTAATACCCAA
CAGACCAACCTGTTCCTGATGGGCCCACTGGTACCCGATGTTCTGGGACTCAGCCTGTCGGCAGATTATCTCGATCGACG
CGAGGATGAAAAACCCAACTCGTTCAGCAAGAACAACAAAAAGTCGATCGACATGACGCTCGGCTTTGCCGCCAATGAGA
CCAATTTGTTCGATCTGAACCTGGTTAAAGGGGAGAAAAAACGTAGCCGGACGGAGAAAGGTGGCGGTACGCCCTGGGGT
TGGGATTTTGATCGTGACGCCCTGAGCCTGACCCACTCGGGTTGGTATGCGGAAGATAGCGTGGCCACCACCAGCTATTT
CCAATACGAAAAAGGCGAGTCGACCTTCCACACCAGCACGCTGGCGCCACAGCATATTCAGAGCGAGAATTATGTGCTGA
ACAGCCAGGCCAAGTTAAGCCTGGGTGAGCACAACCTGACCCTTGGCGCCAACTACAGCCGTGAAACGCTGAATGACGAT
TTCTATGCTGACAGCAAGCGGGCGCCAGGGATTGAGCCCGTCACCAAAATCTCGCGCGACGGCTGGGCGCTGTTCGCCGA
AGGACAATGGAATATTGATGATTTTTCACTGACTACCTCGGCGCGTATGGATCGCGACAACTACTTTGGCACCCACATTA
GCCCGAAACTCTATGGCAACTGGATCCTCGATTCAGCCTGGGCGCTGAAGGGCGGTGTTTCTTCCGGCTATAAAAAACCG
TCGCTGCGGGAAAACTCCGATCAATTCATTACGCCGCGTGGCAGTAACCCGCCTTATCCCTATCTGTCGGTGGGCAACAG
CGAGTTGAAGCCGGAAACCAGCCTGAACACCGAACTGGGGCTGTACTGGAACAACAATCGCGATCTTTCTTTTGATGCAA
CGGTGTTTTATACCGACTTCAAGGACAAGATCGCGGAGGTGAATATCTGTGAAGCGAGCGCGAACCACCCCTGCGTGGTT
AACGGGTATAGCGCAGAATCCATCGATAAGTATTTCAATATTGGCAAGGCCAACGTCTACGGTCTTGAGCTTAACGCAGA
CTGGCAGGCCACGGACCTTCTGAGTTTTAGCGCCAACTACACCTTCAACAAAAGCGAACAGAAAAACGGCGTTAATAAGG
GTTATGCCCTGAATGACTTCCCGAAACACATGGCCAACTTATCCGCCAAGTGGGCAGCGACATCGGCGCTGGACGTCTGG
TCCAAAGTCAATTATCGCAGCCGCAATGAGGAGACCGGCGACCATACCCGCTATGGCGCTTATGCTTTGCTCGATAGCGG
GGTAATTTACCACTTCGACAAACACACCCAGGTGATGGCGGGCGTGTACAACATTTTCGATAGTGCGCCAAAACGCACCA
CCAGTTGGGGAGAATATCCGCAGTTGGAAGGCCGTCGTTATAACCTCGGCTTACGTGTCGATTTCTAA

Upstream 100 bases:

>100_bases
TGATTTTCATTTCGTTTTAATGCGGGAAAATATCCGCTATATTCGCCGCCAACTGTTAAGAACTGTAAATAAAAATACGA
CCAACAGGGGTTATCCGGTG

Downstream 100 bases:

>100_bases
CTTTTGCCGAGCAAATTACCCGGCCGCTTGCCAACTGCGGCCGGGTTAGATCTTTTCTGCCGCTGATTTGATGAGTTAAT
ACCGGAAGGGAATAGTCGGG

Product: TonB-dependent receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 715; Mature: 715

Protein sequence:

>715_residues
MCAVGRYWPLTSCYAAVFGCFAGYNTNRKQVLLGIVMIDQHFMGKRSQIARAMALVLIIAPQAYAQEGEAEQKNNASQED
QLVVTASGFKQNKKYAPASISVIDQKTLEKQNSHDVAEAVQDISGVSVSNGAGTEVSGDVMIRGMDSSYTSFMVNSIKQN
TGESRPYGQNVGTEAGFLPPVAAIDRIEVIRGPMSSLYGSDSIGGVVNVITKKPFGVREWMGSIAANSFLQQHQEFGNTQ
QTNLFLMGPLVPDVLGLSLSADYLDRREDEKPNSFSKNNKKSIDMTLGFAANETNLFDLNLVKGEKKRSRTEKGGGTPWG
WDFDRDALSLTHSGWYAEDSVATTSYFQYEKGESTFHTSTLAPQHIQSENYVLNSQAKLSLGEHNLTLGANYSRETLNDD
FYADSKRAPGIEPVTKISRDGWALFAEGQWNIDDFSLTTSARMDRDNYFGTHISPKLYGNWILDSAWALKGGVSSGYKKP
SLRENSDQFITPRGSNPPYPYLSVGNSELKPETSLNTELGLYWNNNRDLSFDATVFYTDFKDKIAEVNICEASANHPCVV
NGYSAESIDKYFNIGKANVYGLELNADWQATDLLSFSANYTFNKSEQKNGVNKGYALNDFPKHMANLSAKWAATSALDVW
SKVNYRSRNEETGDHTRYGAYALLDSGVIYHFDKHTQVMAGVYNIFDSAPKRTTSWGEYPQLEGRRYNLGLRVDF

Sequences:

>Translated_715_residues
MCAVGRYWPLTSCYAAVFGCFAGYNTNRKQVLLGIVMIDQHFMGKRSQIARAMALVLIIAPQAYAQEGEAEQKNNASQED
QLVVTASGFKQNKKYAPASISVIDQKTLEKQNSHDVAEAVQDISGVSVSNGAGTEVSGDVMIRGMDSSYTSFMVNSIKQN
TGESRPYGQNVGTEAGFLPPVAAIDRIEVIRGPMSSLYGSDSIGGVVNVITKKPFGVREWMGSIAANSFLQQHQEFGNTQ
QTNLFLMGPLVPDVLGLSLSADYLDRREDEKPNSFSKNNKKSIDMTLGFAANETNLFDLNLVKGEKKRSRTEKGGGTPWG
WDFDRDALSLTHSGWYAEDSVATTSYFQYEKGESTFHTSTLAPQHIQSENYVLNSQAKLSLGEHNLTLGANYSRETLNDD
FYADSKRAPGIEPVTKISRDGWALFAEGQWNIDDFSLTTSARMDRDNYFGTHISPKLYGNWILDSAWALKGGVSSGYKKP
SLRENSDQFITPRGSNPPYPYLSVGNSELKPETSLNTELGLYWNNNRDLSFDATVFYTDFKDKIAEVNICEASANHPCVV
NGYSAESIDKYFNIGKANVYGLELNADWQATDLLSFSANYTFNKSEQKNGVNKGYALNDFPKHMANLSAKWAATSALDVW
SKVNYRSRNEETGDHTRYGAYALLDSGVIYHFDKHTQVMAGVYNIFDSAPKRTTSWGEYPQLEGRRYNLGLRVDF
>Mature_715_residues
MCAVGRYWPLTSCYAAVFGCFAGYNTNRKQVLLGIVMIDQHFMGKRSQIARAMALVLIIAPQAYAQEGEAEQKNNASQED
QLVVTASGFKQNKKYAPASISVIDQKTLEKQNSHDVAEAVQDISGVSVSNGAGTEVSGDVMIRGMDSSYTSFMVNSIKQN
TGESRPYGQNVGTEAGFLPPVAAIDRIEVIRGPMSSLYGSDSIGGVVNVITKKPFGVREWMGSIAANSFLQQHQEFGNTQ
QTNLFLMGPLVPDVLGLSLSADYLDRREDEKPNSFSKNNKKSIDMTLGFAANETNLFDLNLVKGEKKRSRTEKGGGTPWG
WDFDRDALSLTHSGWYAEDSVATTSYFQYEKGESTFHTSTLAPQHIQSENYVLNSQAKLSLGEHNLTLGANYSRETLNDD
FYADSKRAPGIEPVTKISRDGWALFAEGQWNIDDFSLTTSARMDRDNYFGTHISPKLYGNWILDSAWALKGGVSSGYKKP
SLRENSDQFITPRGSNPPYPYLSVGNSELKPETSLNTELGLYWNNNRDLSFDATVFYTDFKDKIAEVNICEASANHPCVV
NGYSAESIDKYFNIGKANVYGLELNADWQATDLLSFSANYTFNKSEQKNGVNKGYALNDFPKHMANLSAKWAATSALDVW
SKVNYRSRNEETGDHTRYGAYALLDSGVIYHFDKHTQVMAGVYNIFDSAPKRTTSWGEYPQLEGRRYNLGLRVDF

Specific function: Involved in the initial step of iron uptake by binding ferric vibriobactin, an iron chelatin siderophore that allows V.cholerae to extract iron from the environment [H]

COG id: COG4771

COG function: function code P; Outer membrane receptor for ferrienterochelin and colicins

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=667, Percent_Identity=30.7346326836582, Blast_Score=229, Evalue=4e-61,
Organism=Escherichia coli, GI1786798, Length=724, Percent_Identity=25, Blast_Score=132, Evalue=1e-31,
Organism=Escherichia coli, GI1790405, Length=707, Percent_Identity=21.7821782178218, Blast_Score=92, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 79335; Mature: 79335

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCAVGRYWPLTSCYAAVFGCFAGYNTNRKQVLLGIVMIDQHFMGKRSQIARAMALVLIIA
CCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEEEECHHHCCCHHHHHHHHHHHHEEC
PQAYAQEGEAEQKNNASQEDQLVVTASGFKQNKKYAPASISVIDQKTLEKQNSHDVAEAV
CHHHHCCCCCHHHCCCCCCCEEEEEECCCCCCCCCCCCEEEEHHHHHHHCCCCHHHHHHH
QDISGVSVSNGAGTEVSGDVMIRGMDSSYTSFMVNSIKQNTGESRPYGQNVGTEAGFLPP
HHHCCCEECCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
VAAIDRIEVIRGPMSSLYGSDSIGGVVNVITKKPFGVREWMGSIAANSFLQQHQEFGNTQ
HHHHHHHHHHHCCHHHHCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
QTNLFLMGPLVPDVLGLSLSADYLDRREDEKPNSFSKNNKKSIDMTLGFAANETNLFDLN
CCEEEEECCCCHHHHCCCCCHHHHHCCCCCCCCCCCCCCCCEEEEEEEEECCCCCEEEEE
LVKGEKKRSRTEKGGGTPWGWDFDRDALSLTHSGWYAEDSVATTSYFQYEKGESTFHTST
EECCCHHHHHHHCCCCCCCCCCCCCHHHEEECCCCCCCCCCEEEHEEEECCCCCCEEECC
LAPQHIQSENYVLNSQAKLSLGEHNLTLGANYSRETLNDDFYADSKRAPGIEPVTKISRD
CCHHHHCCCCEEECCCCEEEECCCCEEECCCCCHHHCCCCCCCCCCCCCCCCHHHHHCCC
GWALFAEGQWNIDDFSLTTSARMDRDNYFGTHISPKLYGNWILDSAWALKGGVSSGYKKP
CEEEEECCCCCCCCEEEEHHHCCCCCCCCCCCCCHHHCCCEEECCHHHHCCCCCCCCCCC
SLRENSDQFITPRGSNPPYPYLSVGNSELKPETSLNTELGLYWNNNRDLSFDATVFYTDF
CCCCCCCCEEECCCCCCCCCEEECCCCCCCCCCCCCCEEEEEECCCCCEEEEEEEEEECH
KDKIAEVNICEASANHPCVVNGYSAESIDKYFNIGKANVYGLELNADWQATDLLSFSANY
HHHHCEEEEEECCCCCCEEEECCCHHHHHHHHCCCCCEEEEEEECCCCCCEEEEEECCCC
TFNKSEQKNGVNKGYALNDFPKHMANLSAKWAATSALDVWSKVNYRSRNEETGDHTRYGA
EECCCHHCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCE
YALLDSGVIYHFDKHTQVMAGVYNIFDSAPKRTTSWGEYPQLEGRRYNLGLRVDF
EEEECCCEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEEECC
>Mature Secondary Structure
MCAVGRYWPLTSCYAAVFGCFAGYNTNRKQVLLGIVMIDQHFMGKRSQIARAMALVLIIA
CCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEEEECHHHCCCHHHHHHHHHHHHEEC
PQAYAQEGEAEQKNNASQEDQLVVTASGFKQNKKYAPASISVIDQKTLEKQNSHDVAEAV
CHHHHCCCCCHHHCCCCCCCEEEEEECCCCCCCCCCCCEEEEHHHHHHHCCCCHHHHHHH
QDISGVSVSNGAGTEVSGDVMIRGMDSSYTSFMVNSIKQNTGESRPYGQNVGTEAGFLPP
HHHCCCEECCCCCCCCCCCEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
VAAIDRIEVIRGPMSSLYGSDSIGGVVNVITKKPFGVREWMGSIAANSFLQQHQEFGNTQ
HHHHHHHHHHHCCHHHHCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
QTNLFLMGPLVPDVLGLSLSADYLDRREDEKPNSFSKNNKKSIDMTLGFAANETNLFDLN
CCEEEEECCCCHHHHCCCCCHHHHHCCCCCCCCCCCCCCCCEEEEEEEEECCCCCEEEEE
LVKGEKKRSRTEKGGGTPWGWDFDRDALSLTHSGWYAEDSVATTSYFQYEKGESTFHTST
EECCCHHHHHHHCCCCCCCCCCCCCHHHEEECCCCCCCCCCEEEHEEEECCCCCCEEECC
LAPQHIQSENYVLNSQAKLSLGEHNLTLGANYSRETLNDDFYADSKRAPGIEPVTKISRD
CCHHHHCCCCEEECCCCEEEECCCCEEECCCCCHHHCCCCCCCCCCCCCCCCHHHHHCCC
GWALFAEGQWNIDDFSLTTSARMDRDNYFGTHISPKLYGNWILDSAWALKGGVSSGYKKP
CEEEEECCCCCCCCEEEEHHHCCCCCCCCCCCCCHHHCCCEEECCHHHHCCCCCCCCCCC
SLRENSDQFITPRGSNPPYPYLSVGNSELKPETSLNTELGLYWNNNRDLSFDATVFYTDF
CCCCCCCCEEECCCCCCCCCEEECCCCCCCCCCCCCCEEEEEECCCCCEEEEEEEEEECH
KDKIAEVNICEASANHPCVVNGYSAESIDKYFNIGKANVYGLELNADWQATDLLSFSANY
HHHHCEEEEEECCCCCCEEEECCCHHHHHHHHCCCCCEEEEEEECCCCCCEEEEEECCCC
TFNKSEQKNGVNKGYALNDFPKHMANLSAKWAATSALDVWSKVNYRSRNEETGDHTRYGA
EECCCHHCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCE
YALLDSGVIYHFDKHTQVMAGVYNIFDSAPKRTTSWGEYPQLEGRRYNLGLRVDF
EEEECCCEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1406279; 2174861 [H]