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The map label for this gene is nudK

Identifier: 157371720

GI number: 157371720

Start: 3856868

End: 3857443

Strand: Reverse

Name: nudK

Synonym: Spro_3483

Alternate gene names: 157371720

Gene position: 3857443-3856868 (Counterclockwise)

Preceding gene: 157371721

Following gene: 157371714

Centisome position: 70.79

GC content: 52.6

Gene sequence:

>576_bases
ATGTCGGCGAAAATTGAGAATGTGAAAAAAGAGCTGTTGTCGGATAACTGGTATGTACTGCACAAATATACTTTTGATCT
CAAGCGCAAGGATGGCGGTTCCGTTCAGCAGATGCGCGAAGTCTACGATCGCGGTAACGGTGCGACCATTTTGCTGTATA
ACCGCGCCAAGGGCACGGTGGTACTGACCAATCAATTCCGCATGCCGACCTATGTTAACGGCAATGAGAGTGGCATGCTG
CTGGAGGCCTGTGCGGGCCTGCTGGATGCGGATTCACCGGAACAGTGCGCGCGACGTGAAGCGGTGGAAGAAACCGGTTT
TCAGGTCGGTGAGGTGAAGAAGGTTTTCGAAGCCTATATGTCGCCGGGGGGCGTGACTGAAATTATTCATTTCTTTATCG
CCGAATACCATGACGACGAACGTCATGCGGCCGGTGGCGGTATCGAAGACGAAGATATTGAAGTGGTGGAACTGCCCTTT
ACCGAGGCGGTGGCGATGATCGCCGACGGGCGCATGAAAGACGGCAAGACTATTATGCTGCTGCAGTACCTGCAAATTCA
CCGCATTATGGACTGA

Upstream 100 bases:

>100_bases
GTATGAGCTACGGGGTTTTTTGTTGCAAATCCGTTGTCACTTCGAAGCTTAATCGCGGTATCATTTTTGCGTTTCAGCTA
ACGGAAAAGAAGAAGGGTTC

Downstream 100 bases:

>100_bases
GACAGACTATTCATCTCGCCGGCGAACGGCGAGATGAATCCAACGTGAGTTAGTTAGGTTTGTGGGCGTTAGGCTGGATT
GTCGAGGGTTTTTGCACCAT

Product: NUDIX hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 191; Mature: 190

Protein sequence:

>191_residues
MSAKIENVKKELLSDNWYVLHKYTFDLKRKDGGSVQQMREVYDRGNGATILLYNRAKGTVVLTNQFRMPTYVNGNESGML
LEACAGLLDADSPEQCARREAVEETGFQVGEVKKVFEAYMSPGGVTEIIHFFIAEYHDDERHAAGGGIEDEDIEVVELPF
TEAVAMIADGRMKDGKTIMLLQYLQIHRIMD

Sequences:

>Translated_191_residues
MSAKIENVKKELLSDNWYVLHKYTFDLKRKDGGSVQQMREVYDRGNGATILLYNRAKGTVVLTNQFRMPTYVNGNESGML
LEACAGLLDADSPEQCARREAVEETGFQVGEVKKVFEAYMSPGGVTEIIHFFIAEYHDDERHAAGGGIEDEDIEVVELPF
TEAVAMIADGRMKDGKTIMLLQYLQIHRIMD
>Mature_190_residues
SAKIENVKKELLSDNWYVLHKYTFDLKRKDGGSVQQMREVYDRGNGATILLYNRAKGTVVLTNQFRMPTYVNGNESGMLL
EACAGLLDADSPEQCARREAVEETGFQVGEVKKVFEAYMSPGGVTEIIHFFIAEYHDDERHAAGGGIEDEDIEVVELPFT
EAVAMIADGRMKDGKTIMLLQYLQIHRIMD

Specific function: Catalyzes the hydrolysis of GDP-mannose

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain

Homologues:

Organism=Escherichia coli, GI1788810, Length=191, Percent_Identity=64.3979057591623, Blast_Score=271, Evalue=2e-74,
Organism=Escherichia coli, GI1789412, Length=188, Percent_Identity=31.9148936170213, Blast_Score=91, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24650557, Length=177, Percent_Identity=25.4237288135593, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUDK_SERP5 (A8GHJ1)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001479709.1
- ProteinModelPortal:   A8GHJ1
- SMR:   A8GHJ1
- STRING:   A8GHJ1
- GeneID:   5604912
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_3483
- eggNOG:   COG0494
- HOGENOM:   HBG692398
- OMA:   WHVLRRT
- BioCyc:   SPRO399741:SPRO_3483-MONOMER
- InterPro:   IPR004385
- InterPro:   IPR000086
- InterPro:   IPR015797
- Gene3D:   G3DSA:3.90.79.10
- TIGRFAMs:   TIGR00052

Pfam domain/function: PF00293 NUDIX; SSF55811 NUDIX_hydrolase

EC number: NA

Molecular weight: Translated: 21516; Mature: 21385

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS51462 NUDIX; PS00893 NUDIX_BOX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAKIENVKKELLSDNWYVLHKYTFDLKRKDGGSVQQMREVYDRGNGATILLYNRAKGTV
CCCHHHHHHHHHHCCCCEEEEEEEEEEECCCCCCHHHHHHHHHCCCCCEEEEEECCCCEE
VLTNQFRMPTYVNGNESGMLLEACAGLLDADSPEQCARREAVEETGFQVGEVKKVFEAYM
EEEECCCCCEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHC
SPGGVTEIIHFFIAEYHDDERHAAGGGIEDEDIEVVELPFTEAVAMIADGRMKDGKTIML
CCCCHHHHHHHHHHHHCCCCHHCCCCCCCCCCCEEEECCHHHHHHHHHCCCCCCCCCHHH
LQYLQIHRIMD
HHHHHHHHHCC
>Mature Secondary Structure 
SAKIENVKKELLSDNWYVLHKYTFDLKRKDGGSVQQMREVYDRGNGATILLYNRAKGTV
CCHHHHHHHHHHCCCCEEEEEEEEEEECCCCCCHHHHHHHHHCCCCCEEEEEECCCCEE
VLTNQFRMPTYVNGNESGMLLEACAGLLDADSPEQCARREAVEETGFQVGEVKKVFEAYM
EEEECCCCCEEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHC
SPGGVTEIIHFFIAEYHDDERHAAGGGIEDEDIEVVELPFTEAVAMIADGRMKDGKTIML
CCCCHHHHHHHHHHHHCCCCHHCCCCCCCCCCCEEEECCHHHHHHHHHCCCCCCCCCHHH
LQYLQIHRIMD
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA