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The map label for this gene is ccmB [H]

Identifier: 157371627

GI number: 157371627

Start: 3750126

End: 3750785

Strand: Reverse

Name: ccmB [H]

Synonym: Spro_3390

Alternate gene names: 157371627

Gene position: 3750785-3750126 (Counterclockwise)

Preceding gene: 157371628

Following gene: 157371626

Centisome position: 68.84

GC content: 58.48

Gene sequence:

>660_bases
ATGTTTTTGACCGTATTGCGCCGCGAGCTGAAGATTGCCTTTCGCAAAGGGTCGGAAATCGTTAATCCGCTGTGGTTCTT
TCTGATTGTTATCACGCTGTTTCCGTTAGGGATTGGGCCGGAGCCGCAGTTACTGGCGCGTATATCGCCGGGGATTATTT
GGGTCGCTGCGCTGCTGGCGGCGCTGTTGTCGCTGGAACGTTTGTTTCGCGATGACTTTCTTGATGGCTCGCTGGAGCAA
CTGTTGTTGCTGCCGACGCCGCTGCCAATGACGGTGTTAGGCAAAGTATGTGCTCACTGGGTGGTAACAGGCCTACCCCT
GTTAATCCTGTCGCCGCTGGTGGCGTTGCTGCTGTCGTTGGATATCAATACCTGGCTGGCGGTGGCGTTTACGCTGCTGC
TGGGTACGCCGACGCTGAGTCTGATTGGCGCTATCGGCGTGGCGCTGACCGTCGGGTTGCGCAAGGGCGGCGTGCTGCTT
AGCCTGCTGGTGCTGCCGCTGTATATCCCGGTGTTGATATTTTCCACCGCGGCCATCGATGCCGCCTCTATGGGGATGCC
AATAGACGGTTACCTGGCGATTCTGGGTGCCATGCTGGCGGGCAGTATCACGCTGGCACCGTTCGCTACCGCAGCAGCGC
TGCGAGTGAGCGTGCACTAG

Upstream 100 bases:

>100_bases
AGGGCGGCATGGTATTGTTGACCACCCATCAGGATTTGGCCGGCGTAACGCAGGCGGTAGGTAAAATCAGCCTGACGGAA
AACCGCATGGAGACTGTTTG

Downstream 100 bases:

>100_bases
CTAACATATTGAAATGCGGGTTAACGCCATCAAGAGCGTGTTGCACCGCACCAGTAATTTTCGTCGCCTTGGTCAACAGG
GCGGCCACCGTATAAATTTA

Product: heme exporter protein CcmB

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein CcmB [H]

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MFLTVLRRELKIAFRKGSEIVNPLWFFLIVITLFPLGIGPEPQLLARISPGIIWVAALLAALLSLERLFRDDFLDGSLEQ
LLLLPTPLPMTVLGKVCAHWVVTGLPLLILSPLVALLLSLDINTWLAVAFTLLLGTPTLSLIGAIGVALTVGLRKGGVLL
SLLVLPLYIPVLIFSTAAIDAASMGMPIDGYLAILGAMLAGSITLAPFATAAALRVSVH

Sequences:

>Translated_219_residues
MFLTVLRRELKIAFRKGSEIVNPLWFFLIVITLFPLGIGPEPQLLARISPGIIWVAALLAALLSLERLFRDDFLDGSLEQ
LLLLPTPLPMTVLGKVCAHWVVTGLPLLILSPLVALLLSLDINTWLAVAFTLLLGTPTLSLIGAIGVALTVGLRKGGVLL
SLLVLPLYIPVLIFSTAAIDAASMGMPIDGYLAILGAMLAGSITLAPFATAAALRVSVH
>Mature_219_residues
MFLTVLRRELKIAFRKGSEIVNPLWFFLIVITLFPLGIGPEPQLLARISPGIIWVAALLAALLSLERLFRDDFLDGSLEQ
LLLLPTPLPMTVLGKVCAHWVVTGLPLLILSPLVALLLSLDINTWLAVAFTLLLGTPTLSLIGAIGVALTVGLRKGGVLL
SLLVLPLYIPVLIFSTAAIDAASMGMPIDGYLAILGAMLAGSITLAPFATAAALRVSVH

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes [H]

COG id: COG2386

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmB/CycW/HelB family [H]

Homologues:

Organism=Escherichia coli, GI1788528, Length=219, Percent_Identity=74.4292237442922, Blast_Score=266, Evalue=6e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003544 [H]

Pfam domain/function: PF03379 CcmB [H]

EC number: NA

Molecular weight: Translated: 23276; Mature: 23276

Theoretical pI: Translated: 8.51; Mature: 8.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLTVLRRELKIAFRKGSEIVNPLWFFLIVITLFPLGIGPEPQLLARISPGIIWVAALLA
CHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHH
ALLSLERLFRDDFLDGSLEQLLLLPTPLPMTVLGKVCAHWVVTGLPLLILSPLVALLLSL
HHHHHHHHHHHHCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DINTWLAVAFTLLLGTPTLSLIGAIGVALTVGLRKGGVLLSLLVLPLYIPVLIFSTAAID
CHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
AASMGMPIDGYLAILGAMLAGSITLAPFATAAALRVSVH
HHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHEECC
>Mature Secondary Structure
MFLTVLRRELKIAFRKGSEIVNPLWFFLIVITLFPLGIGPEPQLLARISPGIIWVAALLA
CHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHH
ALLSLERLFRDDFLDGSLEQLLLLPTPLPMTVLGKVCAHWVVTGLPLLILSPLVALLLSL
HHHHHHHHHHHHCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DINTWLAVAFTLLLGTPTLSLIGAIGVALTVGLRKGGVLLSLLVLPLYIPVLIFSTAAID
CHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
AASMGMPIDGYLAILGAMLAGSITLAPFATAAALRVSVH
HHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]