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The map label for this gene is yfcB [H]

Identifier: 157371612

GI number: 157371612

Start: 3735164

End: 3736138

Strand: Reverse

Name: yfcB [H]

Synonym: Spro_3375

Alternate gene names: 157371612

Gene position: 3736138-3735164 (Counterclockwise)

Preceding gene: 157371614

Following gene: 157371611

Centisome position: 68.57

GC content: 55.28

Gene sequence:

>975_bases
ATGCGGCTAAATCATGAATCACAGTGCCTGCCGGAGGGCAAATTGGACAAAATTTTCGTCGAGGAAGCAGTGAATGAACT
GCACACCATTCAAGATATGCTGCGTTGGACAGTAAGCCGTTTTAACGCCGCCGATATCTACTATGGTCACGGAACCGATA
ATCCGTGGGACGAAGCGGTGCAATTGGTGCTGCCAAGCCTGTTCCTGCCGCTGGATATTCCAGAGGACATGCACACTGCA
CGTTTGACCTCCAGCGAACGCCACCGCATCGTTGAACGCGTGATCCGCCGCGTCAATGAGCGTATTCCGGTAGCCTACCT
GACCAACAAAGCCTGGTTCTGCGACCTGGAGTTTTATGTCGATGAGCGCGTGCTGGTACCGCGTTCCCCGATTGGCGAAT
TGATCAACGATCGCTTCAGCGCACTGATCCCTCATTCGCCGAGCCATATTCTCGACATGTGTACCGGCAGCGGCTGCATT
GCCATTGCCTGCGGCTATGCTTTCCCGGATGCGGAAGTGGACGCGGTAGACATCTCCGCCGACGTGCTGGCGGTGACCGA
GCGCAATATTCAGGCGCTGGGCGTTGAACAGCAGGTGACTCCGATCCGTTCCGATCTGTTCCGCGATCTTCCGGCGATCC
AGTACGATCTGATTGTCACCAACCCACCGTACGTTGATGCAGAAGACATGTCTGATCTGCCGGAAGAGTTCCGCTTTGAA
CCTGAACTGGGTCTGGCGGCGGGTAGCGACGGTCTGAAGCTGGTGCGTCGCATTCTGGCCTGTGCGCCGGATTACCTGAG
CGACGACGGCGTGCTGATTTGTGAAGTGGGTAACAGCATGGTACATCTGATGGAACAGTATCCGGATATTCCGTTCAGCT
GGCTGGAGTTTGAAAACGGCGGTGACGGGGTGTTCATGCTGACCAAACAGCAACTGGTAGATTGCAAAGAGCATTTCAGC
CTCTACCGCAGCTAA

Upstream 100 bases:

>100_bases
GGTAGTTTACCGTGTCGCGGGTATCTGTCGACGCAAAATTCGCGCCAAAATGAAAAGCGCAAGGGGTTAGCGTGATTTGT
CGCGGGCTTCATGGCAAACT

Downstream 100 bases:

>100_bases
GCATTCTCCGGGCCTGTCCTCGCGGGCCCAACAAAGATAATAATTAAGGGTAAGGATCCGCGATGGCAGGAAACAGTATT
GGGCAGATTTTCCGCGTCAC

Product: N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MRLNHESQCLPEGKLDKIFVEEAVNELHTIQDMLRWTVSRFNAADIYYGHGTDNPWDEAVQLVLPSLFLPLDIPEDMHTA
RLTSSERHRIVERVIRRVNERIPVAYLTNKAWFCDLEFYVDERVLVPRSPIGELINDRFSALIPHSPSHILDMCTGSGCI
AIACGYAFPDAEVDAVDISADVLAVTERNIQALGVEQQVTPIRSDLFRDLPAIQYDLIVTNPPYVDAEDMSDLPEEFRFE
PELGLAAGSDGLKLVRRILACAPDYLSDDGVLICEVGNSMVHLMEQYPDIPFSWLEFENGGDGVFMLTKQQLVDCKEHFS
LYRS

Sequences:

>Translated_324_residues
MRLNHESQCLPEGKLDKIFVEEAVNELHTIQDMLRWTVSRFNAADIYYGHGTDNPWDEAVQLVLPSLFLPLDIPEDMHTA
RLTSSERHRIVERVIRRVNERIPVAYLTNKAWFCDLEFYVDERVLVPRSPIGELINDRFSALIPHSPSHILDMCTGSGCI
AIACGYAFPDAEVDAVDISADVLAVTERNIQALGVEQQVTPIRSDLFRDLPAIQYDLIVTNPPYVDAEDMSDLPEEFRFE
PELGLAAGSDGLKLVRRILACAPDYLSDDGVLICEVGNSMVHLMEQYPDIPFSWLEFENGGDGVFMLTKQQLVDCKEHFS
LYRS
>Mature_324_residues
MRLNHESQCLPEGKLDKIFVEEAVNELHTIQDMLRWTVSRFNAADIYYGHGTDNPWDEAVQLVLPSLFLPLDIPEDMHTA
RLTSSERHRIVERVIRRVNERIPVAYLTNKAWFCDLEFYVDERVLVPRSPIGELINDRFSALIPHSPSHILDMCTGSGCI
AIACGYAFPDAEVDAVDISADVLAVTERNIQALGVEQQVTPIRSDLFRDLPAIQYDLIVTNPPYVDAEDMSDLPEEFRFE
PELGLAAGSDGLKLVRRILACAPDYLSDDGVLICEVGNSMVHLMEQYPDIPFSWLEFENGGDGVFMLTKQQLVDCKEHFS
LYRS

Specific function: Unknown

COG id: COG2890

COG function: function code J; Methylase of polypeptide chain release factors

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI7705409, Length=233, Percent_Identity=30.9012875536481, Blast_Score=86, Evalue=4e-17,
Organism=Escherichia coli, GI87082085, Length=309, Percent_Identity=81.8770226537217, Blast_Score=539, Evalue=1e-154,
Organism=Escherichia coli, GI1787463, Length=194, Percent_Identity=32.4742268041237, Blast_Score=104, Evalue=7e-24,
Organism=Drosophila melanogaster, GI24582226, Length=198, Percent_Identity=26.7676767676768, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002052
- InterPro:   IPR004556
- InterPro:   IPR017127
- InterPro:   IPR007848 [H]

Pfam domain/function: PF05175 MTS [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 36673; Mature: 36673

Theoretical pI: Translated: 4.27; Mature: 4.27

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLNHESQCLPEGKLDKIFVEEAVNELHTIQDMLRWTVSRFNAADIYYGHGTDNPWDEAV
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHH
QLVLPSLFLPLDIPEDMHTARLTSSERHRIVERVIRRVNERIPVAYLTNKAWFCDLEFYV
HHHHHHHHCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHCCCEEEEECCEEEEEEEEEE
DERVLVPRSPIGELINDRFSALIPHSPSHILDMCTGSGCIAIACGYAFPDAEVDAVDISA
CCEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCEEEECCC
DVLAVTERNIQALGVEQQVTPIRSDLFRDLPAIQYDLIVTNPPYVDAEDMSDLPEEFRFE
CEEEEECCCHHHCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHCCHHHHCCC
PELGLAAGSDGLKLVRRILACAPDYLSDDGVLICEVGNSMVHLMEQYPDIPFSWLEFENG
CCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHCCCCCEEEEEECCC
GDGVFMLTKQQLVDCKEHFSLYRS
CCEEEEEEHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRLNHESQCLPEGKLDKIFVEEAVNELHTIQDMLRWTVSRFNAADIYYGHGTDNPWDEAV
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHH
QLVLPSLFLPLDIPEDMHTARLTSSERHRIVERVIRRVNERIPVAYLTNKAWFCDLEFYV
HHHHHHHHCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHCCCEEEEECCEEEEEEEEEE
DERVLVPRSPIGELINDRFSALIPHSPSHILDMCTGSGCIAIACGYAFPDAEVDAVDISA
CCEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEEEEECCCCCCCCCEEEECCC
DVLAVTERNIQALGVEQQVTPIRSDLFRDLPAIQYDLIVTNPPYVDAEDMSDLPEEFRFE
CEEEEECCCHHHCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHCCHHHHCCC
PELGLAAGSDGLKLVRRILACAPDYLSDDGVLICEVGNSMVHLMEQYPDIPFSWLEFENG
CCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHCCCCCEEEEEECCC
GDGVFMLTKQQLVDCKEHFSLYRS
CCEEEEEEHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503; 2182772; 2969724; 7984428 [H]