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The map label for this gene is cusB [H]

Identifier: 157371600

GI number: 157371600

Start: 3723823

End: 3725274

Strand: Reverse

Name: cusB [H]

Synonym: Spro_3363

Alternate gene names: 157371600

Gene position: 3725274-3723823 (Counterclockwise)

Preceding gene: 157371601

Following gene: 157371599

Centisome position: 68.37

GC content: 60.33

Gene sequence:

>1452_bases
ATGAGAATGCCATTTAAGCTGGCGCTGTTAGCGGCGTTAATCGGCGGTGGGCTGGCCGGGTATGGGTTGGGTTCGGCGGG
GGAGGCCGCGCCGCAGGCAGACAAAACGGAACGACAGGTACTGTATTGGTACGATCCGATGATGCCTGCCCAGCGCTTTG
ATAAGCCGGGGAAATCCCCCTTTATGGATATGCAACTGGTGCCGCGCTATGCCGATGAGGCCGAGACGCAGGGCGGTGTG
ACCATCAGTGCGCGCCAGCAGCAGAATCTGGGGGTACGTATTGAGACCGCTCAGTTGCGCGCGTTGGAGCAGCAGCTTGA
CGCTTTTGGCAGCGTAGCGACGGATGAGCGTGGGGTGCAGATTATTGCCGCCCGTGCCAATGGGCTGGTGGAAAAACTCT
ATGTCCGTGCCAGCCAGCAGCAGGTGAAAAAAGGCCAGCCGCTGGCACAGTTGTGGATCCCGGAGTGGAGTGCGGCACAG
CAGGAGTATTTGGCGATACGGCAACTGGGCGATCGCGCATTGACCGCTGCCGCCCGCCAGCGGTTGCAGCTGTTATTTAT
ACCCGAGGCGGTGATACGGCAGGTTGAGCGCACGGGCAAGCCCGAGCCACGTATTAAAATAGTGGCGCCGGAGAGCGGAT
ATGTGAACAAGCTAAGCGTGCTTGAGGGCGCTCAGGTGACCGCGGCGCAGGGGTTGTTTGAGCTGGCGAGGCTGGATCCG
GTGTGGATCGTGGCTGACTATCCGCAGGCGCAGGCCGGGTTACTCAAGGTGGGCGACAAGGTGCAGGCCGCCTCTGCCAG
CTGGCCGGGGGAAAGGTTTGCAGGCGAGGTGAGCGAACTGCTGGCCAATGTCGATCCGCTAACCCGCACCTTCAAAGCGC
GCATTCTGTTAAAAAATCCTCAGCAAAAGCTGCGGCCAGGCATGTACCTGCAACTGACGCTATCGCAGAACGCCGTCGGC
AAACCGGTGCTGGCAATCCCGCAGGAGGCGCTGATAGATAACGGCGATCGTAACCGGGTATTGGTTGCCGAAGGTAACGG
CCATTTCACGCCGGTGGAGGTGGTGGCCGGGCGCGTACAGGATGGCTGGGTGGAGATCAAACGCGGGCTGAGCGCCGGGC
AACAGGTGGTGACCTCCGGTCAGTTCCTGATCGACTCCGAGGCCAGTATGCGCAGTGCCTTGCCGCAGATGGCGGCACAA
ACCGAAGTTAAACAGTATCAGGCCGAAGGGGTGATTGAGGCACTCAATGGCGACACCATGACGTTGTCCCACGGACCGGT
ACCTGAATTGCAGTGGCCGGCGATGACCATGGATTTTGCTCTGCCGTCGGGGGGATTACCGGCAGGCATCAAGCCTGGCG
ACCGGGTAAAAATTCACTTTAGCGTCGACGACAGCGGTTCACATATCAGCCAGGTTCTGCCGATCAATGCCGGGCACGGA
GGCCACTTATGA

Upstream 100 bases:

>100_bases
GGGCGCTGCTCGACAGCCGCCTCAGCGCCGGTAAAGCCGCCCGTGGACTGGCGCAGTTTTGGGCCGCCATCCGCTATCTC
ACCCCTCAGGAGGCAATGCA

Downstream 100 bases:

>100_bases
TTGCATTCGTGATCCGCTGGTCGCTGCGCAACCGGCTGCTGGTGTTATTGGCCTCGGTGTTGTTGGCCGGTTGGGGTGTG
TGGGCACTGCAGAAAGCGCC

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 483; Mature: 483

Protein sequence:

>483_residues
MRMPFKLALLAALIGGGLAGYGLGSAGEAAPQADKTERQVLYWYDPMMPAQRFDKPGKSPFMDMQLVPRYADEAETQGGV
TISARQQQNLGVRIETAQLRALEQQLDAFGSVATDERGVQIIAARANGLVEKLYVRASQQQVKKGQPLAQLWIPEWSAAQ
QEYLAIRQLGDRALTAAARQRLQLLFIPEAVIRQVERTGKPEPRIKIVAPESGYVNKLSVLEGAQVTAAQGLFELARLDP
VWIVADYPQAQAGLLKVGDKVQAASASWPGERFAGEVSELLANVDPLTRTFKARILLKNPQQKLRPGMYLQLTLSQNAVG
KPVLAIPQEALIDNGDRNRVLVAEGNGHFTPVEVVAGRVQDGWVEIKRGLSAGQQVVTSGQFLIDSEASMRSALPQMAAQ
TEVKQYQAEGVIEALNGDTMTLSHGPVPELQWPAMTMDFALPSGGLPAGIKPGDRVKIHFSVDDSGSHISQVLPINAGHG
GHL

Sequences:

>Translated_483_residues
MRMPFKLALLAALIGGGLAGYGLGSAGEAAPQADKTERQVLYWYDPMMPAQRFDKPGKSPFMDMQLVPRYADEAETQGGV
TISARQQQNLGVRIETAQLRALEQQLDAFGSVATDERGVQIIAARANGLVEKLYVRASQQQVKKGQPLAQLWIPEWSAAQ
QEYLAIRQLGDRALTAAARQRLQLLFIPEAVIRQVERTGKPEPRIKIVAPESGYVNKLSVLEGAQVTAAQGLFELARLDP
VWIVADYPQAQAGLLKVGDKVQAASASWPGERFAGEVSELLANVDPLTRTFKARILLKNPQQKLRPGMYLQLTLSQNAVG
KPVLAIPQEALIDNGDRNRVLVAEGNGHFTPVEVVAGRVQDGWVEIKRGLSAGQQVVTSGQFLIDSEASMRSALPQMAAQ
TEVKQYQAEGVIEALNGDTMTLSHGPVPELQWPAMTMDFALPSGGLPAGIKPGDRVKIHFSVDDSGSHISQVLPINAGHG
GHL
>Mature_483_residues
MRMPFKLALLAALIGGGLAGYGLGSAGEAAPQADKTERQVLYWYDPMMPAQRFDKPGKSPFMDMQLVPRYADEAETQGGV
TISARQQQNLGVRIETAQLRALEQQLDAFGSVATDERGVQIIAARANGLVEKLYVRASQQQVKKGQPLAQLWIPEWSAAQ
QEYLAIRQLGDRALTAAARQRLQLLFIPEAVIRQVERTGKPEPRIKIVAPESGYVNKLSVLEGAQVTAAQGLFELARLDP
VWIVADYPQAQAGLLKVGDKVQAASASWPGERFAGEVSELLANVDPLTRTFKARILLKNPQQKLRPGMYLQLTLSQNAVG
KPVLAIPQEALIDNGDRNRVLVAEGNGHFTPVEVVAGRVQDGWVEIKRGLSAGQQVVTSGQFLIDSEASMRSALPQMAAQ
TEVKQYQAEGVIEALNGDTMTLSHGPVPELQWPAMTMDFALPSGGLPAGIKPGDRVKIHFSVDDSGSHISQVLPINAGHG
GHL

Specific function: Part of a cation efflux system that mediates resistance to copper and silver [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1786787, Length=404, Percent_Identity=37.8712871287129, Blast_Score=262, Evalue=3e-71,
Organism=Escherichia coli, GI87081796, Length=178, Percent_Identity=33.1460674157303, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006143 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 52275; Mature: 52275

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRMPFKLALLAALIGGGLAGYGLGSAGEAAPQADKTERQVLYWYDPMMPAQRFDKPGKSP
CCCCHHHHHHHHHHCCCHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHCCCCCCCC
FMDMQLVPRYADEAETQGGVTISARQQQNLGVRIETAQLRALEQQLDAFGSVATDERGVQ
CCCHHHCCCHHHHCCCCCCEEEEECCCCCCCEEEEHHHHHHHHHHHHHHCCCCCCCCCEE
IIAARANGLVEKLYVRASQQQVKKGQPLAQLWIPEWSAAQQEYLAIRQLGDRALTAAARQ
EEEECHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
RLQLLFIPEAVIRQVERTGKPEPRIKIVAPESGYVNKLSVLEGAQVTAAQGLFELARLDP
CEEEEECCHHHHHHHHHCCCCCCCEEEECCCCCCCCEEHHHCCCCHHHHHHHHHHHHCCC
VWIVADYPQAQAGLLKVGDKVQAASASWPGERFAGEVSELLANVDPLTRTFKARILLKNP
EEEEECCCCCCCCHHHCCCCCEECCCCCCCHHHHHHHHHHHHCCCHHHHHHEEEEEEECC
QQKLRPGMYLQLTLSQNAVGKPVLAIPQEALIDNGDRNRVLVAEGNGHFTPVEVVAGRVQ
HHHCCCCEEEEEEECCCCCCCCEEECCHHHHHCCCCCCEEEEECCCCCCCHHHHHHCCCC
DGWVEIKRGLSAGQQVVTSGQFLIDSEASMRSALPQMAAQTEVKQYQAEGVIEALNGDTM
HHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCEE
TLSHGPVPELQWPAMTMDFALPSGGLPAGIKPGDRVKIHFSVDDSGSHISQVLPINAGHG
EECCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEEEEECCCCCCCHHEEEEECCCC
GHL
CCC
>Mature Secondary Structure
MRMPFKLALLAALIGGGLAGYGLGSAGEAAPQADKTERQVLYWYDPMMPAQRFDKPGKSP
CCCCHHHHHHHHHHCCCHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHCCCCCCCC
FMDMQLVPRYADEAETQGGVTISARQQQNLGVRIETAQLRALEQQLDAFGSVATDERGVQ
CCCHHHCCCHHHHCCCCCCEEEEECCCCCCCEEEEHHHHHHHHHHHHHHCCCCCCCCCEE
IIAARANGLVEKLYVRASQQQVKKGQPLAQLWIPEWSAAQQEYLAIRQLGDRALTAAARQ
EEEECHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
RLQLLFIPEAVIRQVERTGKPEPRIKIVAPESGYVNKLSVLEGAQVTAAQGLFELARLDP
CEEEEECCHHHHHHHHHCCCCCCCEEEECCCCCCCCEEHHHCCCCHHHHHHHHHHHHCCC
VWIVADYPQAQAGLLKVGDKVQAASASWPGERFAGEVSELLANVDPLTRTFKARILLKNP
EEEEECCCCCCCCHHHCCCCCEECCCCCCCHHHHHHHHHHHHCCCHHHHHHEEEEEEECC
QQKLRPGMYLQLTLSQNAVGKPVLAIPQEALIDNGDRNRVLVAEGNGHFTPVEVVAGRVQ
HHHCCCCEEEEEEECCCCCCCCEEECCHHHHHCCCCCCEEEEECCCCCCCHHHHHHCCCC
DGWVEIKRGLSAGQQVVTSGQFLIDSEASMRSALPQMAAQTEVKQYQAEGVIEALNGDTM
HHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCEE
TLSHGPVPELQWPAMTMDFALPSGGLPAGIKPGDRVKIHFSVDDSGSHISQVLPINAGHG
EECCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEEEEECCCCCCCHHEEEEECCCC
GHL
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]