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The map label for this gene is tctD [H]

Identifier: 157371577

GI number: 157371577

Start: 3696797

End: 3697471

Strand: Reverse

Name: tctD [H]

Synonym: Spro_3340

Alternate gene names: 157371577

Gene position: 3697471-3696797 (Counterclockwise)

Preceding gene: 157371578

Following gene: 157371576

Centisome position: 67.86

GC content: 58.96

Gene sequence:

>675_bases
ATGCGTCTGTTATTGGTTGAAGACCATCCCGAGTTATCCCACTGGCTGCAAAAGGCGCTGACCGGCGTCGGTTTTGCTGT
CGACGTCGCGCCGGACGGGCTGGCGGCCGACCACTTGTTGTTAAACGAGAGCTATGCGCTGGTGGTACTGGATGTAGCGC
TGCCGCGGCTGAATGGTCTGGAACTGTTGGCCCGGCTGCGCAAGCGCGGGCAGGATTTGCCGGTGCTGTTGCTGACGGCC
AGAACCGACGTTGCCGATCGCGTCAAAGGGCTGAATCTGGGGGCCGACGATTACCTGACCAAACCGTTCGAACTCGATGA
ATTGGAAGCGCGTATTCGGGCGTTGCTGCGCCGCAGCGTCGGCGTTACCCAGCAGGCGCTGCAGTATGGTGCGCTGACCT
ATCACGATGAAGGTTATTTCCAACTCGACGACAAACCGCTGCAGTTGACGCCCCGAGAGTTGGCGGTGCTGACCGCCTTG
ATCCACCGGCGTGGCCGCCCGGTTGCCAAACAGCAGCTGTTTGAACAGGTATTTACCCTGTCTGATGAAGCCAACCCGGA
AAGCATCGAACTGTACGTTCATCGGCTGCGGAAAAAGCTGCAGGGCAGCAATGTGGCGATCATCACCCTGCGTGGTCTGG
GCTACAGCCTGGAGCTTTGCAATGAGGTGGTTTAA

Upstream 100 bases:

>100_bases
ATGCCATCCTGCTGTTATAAATATGTTAATTTGCCGTCATCCTGGCCTGGTGGTTATTTCACCGAGGGCATAGGCATAGA
TAAATCAATGGAATGGAAAC

Downstream 100 bases:

>100_bases
CGCGCCACGCTCACTGTTTTATCAACTGTTGTTGTTCTTTGGCCTGCCACTGCTGGTGCTGGGCGGCATCTCGATATATA
CCCACTACTTTAGCGCGATG

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MRLLLVEDHPELSHWLQKALTGVGFAVDVAPDGLAADHLLLNESYALVVLDVALPRLNGLELLARLRKRGQDLPVLLLTA
RTDVADRVKGLNLGADDYLTKPFELDELEARIRALLRRSVGVTQQALQYGALTYHDEGYFQLDDKPLQLTPRELAVLTAL
IHRRGRPVAKQQLFEQVFTLSDEANPESIELYVHRLRKKLQGSNVAIITLRGLGYSLELCNEVV

Sequences:

>Translated_224_residues
MRLLLVEDHPELSHWLQKALTGVGFAVDVAPDGLAADHLLLNESYALVVLDVALPRLNGLELLARLRKRGQDLPVLLLTA
RTDVADRVKGLNLGADDYLTKPFELDELEARIRALLRRSVGVTQQALQYGALTYHDEGYFQLDDKPLQLTPRELAVLTAL
IHRRGRPVAKQQLFEQVFTLSDEANPESIELYVHRLRKKLQGSNVAIITLRGLGYSLELCNEVV
>Mature_224_residues
MRLLLVEDHPELSHWLQKALTGVGFAVDVAPDGLAADHLLLNESYALVVLDVALPRLNGLELLARLRKRGQDLPVLLLTA
RTDVADRVKGLNLGADDYLTKPFELDELEARIRALLRRSVGVTQQALQYGALTYHDEGYFQLDDKPLQLTPRELAVLTAL
IHRRGRPVAKQQLFEQVFTLSDEANPESIELYVHRLRKKLQGSNVAIITLRGLGYSLELCNEVV

Specific function: Transcriptional activator of the tctI tricarboxylate transport system operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789402, Length=219, Percent_Identity=40.1826484018265, Blast_Score=151, Evalue=3e-38,
Organism=Escherichia coli, GI1790552, Length=224, Percent_Identity=41.0714285714286, Blast_Score=147, Evalue=4e-37,
Organism=Escherichia coli, GI1786784, Length=235, Percent_Identity=36.1702127659575, Blast_Score=139, Evalue=1e-34,
Organism=Escherichia coli, GI1787375, Length=222, Percent_Identity=35.5855855855856, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI87082012, Length=220, Percent_Identity=33.6363636363636, Blast_Score=131, Evalue=3e-32,
Organism=Escherichia coli, GI1789809, Length=231, Percent_Identity=35.0649350649351, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1790860, Length=221, Percent_Identity=35.2941176470588, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1786599, Length=223, Percent_Identity=32.2869955156951, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI1787229, Length=225, Percent_Identity=32.8888888888889, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI2367329, Length=228, Percent_Identity=38.5964912280702, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1788394, Length=225, Percent_Identity=31.5555555555556, Blast_Score=100, Evalue=6e-23,
Organism=Escherichia coli, GI1786911, Length=226, Percent_Identity=30.5309734513274, Blast_Score=94, Evalue=7e-21,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=26.7543859649123, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1787487, Length=120, Percent_Identity=36.6666666666667, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1788550, Length=107, Percent_Identity=35.5140186915888, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788713, Length=115, Percent_Identity=35.6521739130435, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1790299, Length=126, Percent_Identity=30.1587301587302, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI145693157, Length=106, Percent_Identity=33.9622641509434, Blast_Score=63, Evalue=1e-11,
Organism=Escherichia coli, GI1790437, Length=114, Percent_Identity=32.4561403508772, Blast_Score=61, Evalue=7e-11,
Organism=Escherichia coli, GI1788905, Length=131, Percent_Identity=32.0610687022901, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25103; Mature: 25103

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLLLVEDHPELSHWLQKALTGVGFAVDVAPDGLAADHLLLNESYALVVLDVALPRLNGL
CEEEEECCCCHHHHHHHHHHHHCCEEEEECCCCCCHHHEEECCCCEEEEEEECCCCCCHH
ELLARLRKRGQDLPVLLLTARTDVADRVKGLNLGADDYLTKPFELDELEARIRALLRRSV
HHHHHHHHCCCCCCEEEEEECCCHHHHHHCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHC
GVTQQALQYGALTYHDEGYFQLDDKPLQLTPRELAVLTALIHRRGRPVAKQQLFEQVFTL
CHHHHHHHHCCEEEECCCEEEECCCCCEECHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
SDEANPESIELYVHRLRKKLQGSNVAIITLRGLGYSLELCNEVV
CCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHCCC
>Mature Secondary Structure
MRLLLVEDHPELSHWLQKALTGVGFAVDVAPDGLAADHLLLNESYALVVLDVALPRLNGL
CEEEEECCCCHHHHHHHHHHHHCCEEEEECCCCCCHHHEEECCCCEEEEEEECCCCCCHH
ELLARLRKRGQDLPVLLLTARTDVADRVKGLNLGADDYLTKPFELDELEARIRALLRRSV
HHHHHHHHCCCCCCEEEEEECCCHHHHHHCCCCCCHHHCCCCCCHHHHHHHHHHHHHHHC
GVTQQALQYGALTYHDEGYFQLDDKPLQLTPRELAVLTALIHRRGRPVAKQQLFEQVFTL
CHHHHHHHHCCEEEECCCEEEECCCCCEECHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
SDEANPESIELYVHRLRKKLQGSNVAIITLRGLGYSLELCNEVV
CCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2666399; 11083839; 11677609 [H]