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The map label for this gene is usg [H]

Identifier: 157371572

GI number: 157371572

Start: 3690274

End: 3691284

Strand: Reverse

Name: usg [H]

Synonym: Spro_3335

Alternate gene names: 157371572

Gene position: 3691284-3690274 (Counterclockwise)

Preceding gene: 157371573

Following gene: 157371571

Centisome position: 67.74

GC content: 60.63

Gene sequence:

>1011_bases
ATGTCTGACGGCTGGAATATCGCTCTGCTTGGCGCCACTGGCGCGGTAGGTGAAGCGTTGCTGGAATTATTACAGGAACG
CCAGTTCCCGGTGGGCGAACTCTATCCATTGGCAAGTGAACGCAGCGCCGGTGCCACGGTGCGCTTCAACGGCAAATCGG
TACTGGTGCAAAACGCGGAAGAATTTGACTGGTCACAGGCGCAGTTGGCGTTCTTCGTTGCCGGAACCGAGGCTTCGGCC
CGCTACGCGGAAGAAGCCGGCAACATGGGCTGCCTGGTGATCGACACCAGCGGCCTGTTTGCGCTGGAGCCGGACGTGCC
GCTGGTGGTTCCTGGGGTGAACCCACAGGTGCTGGCGGATTACCGCAACCGCAATATCGTTGCCGTGGCCGACAGCATGG
TTAGCCAACTGCTGACCGCGATCAAACCGCTGACCGAACAGGCCGGGCTTTCCCGTCTGCACGTCACCACCCTGATGTCA
GTATCGGCACGCGGCAAAGCGGCGGTCGACGATCTGGCCGGTCAAAGTGCGCGCCTGCTGAACGGCATTCCGGCTGAAGC
GGGCGTTTTCGCCAAGCAGTTGGCGTTCAACCTGCTGCCGTTGCTGGCCGACGAACAGGGCAGCGTGCGCGAAGAGCGTT
TGATTGTCGATCAGGTGCGTAAAGTGCTGCAGGACGAAGGGCTGCCGATTTCCGTGAGCTGTGTGCAGTCGCCGGTGTTC
TACGGCCATGCGCAGGTGGTTCACCTGGAAGCGTTGCGCCCGATGTCTGCGGAAGAAGCGCGCAGCGAGCTGGAACAGGT
GGATGATATCCAACTGAGTGAAGAAGACGACTACCCGACCCAGGTGACGGAAGCCTCTGGCAGCGATGCGCTGAGCGTTG
GCTGTTTGCGTAATGACTATGGTATTCCGGAAATCCTGCAGTTCTGGTCGGTGGCCGACAACGTGCGTTTCGGCGGCGCG
CTGATGGCGATCGAAACCGCAGAACGTCTGGTGCAGGAGCAGATGTACTGA

Upstream 100 bases:

>100_bases
GACGGCATAAGGCTTTCTTAAGCCACGGCGACTAATTTTGTTATCAGGGCGGTGCAGTAGCCGCCCATCTGCATTTGAAT
AAATACTCTGGAGAAACCCA

Downstream 100 bases:

>100_bases
TGTCTGAAGTTGTCTTGCCCACCCAGCCGACGTTGAAAATCGCGCTGGGGATTGAATATGACGGCAGCCAGTATTACGGC
TGGCAGCGTCAGCAGGAAGT

Product: putative semialdehyde dehydrogenase

Products: L-4-aspartyl phosphate; NADPH; H+

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MSDGWNIALLGATGAVGEALLELLQERQFPVGELYPLASERSAGATVRFNGKSVLVQNAEEFDWSQAQLAFFVAGTEASA
RYAEEAGNMGCLVIDTSGLFALEPDVPLVVPGVNPQVLADYRNRNIVAVADSMVSQLLTAIKPLTEQAGLSRLHVTTLMS
VSARGKAAVDDLAGQSARLLNGIPAEAGVFAKQLAFNLLPLLADEQGSVREERLIVDQVRKVLQDEGLPISVSCVQSPVF
YGHAQVVHLEALRPMSAEEARSELEQVDDIQLSEEDDYPTQVTEASGSDALSVGCLRNDYGIPEILQFWSVADNVRFGGA
LMAIETAERLVQEQMY

Sequences:

>Translated_336_residues
MSDGWNIALLGATGAVGEALLELLQERQFPVGELYPLASERSAGATVRFNGKSVLVQNAEEFDWSQAQLAFFVAGTEASA
RYAEEAGNMGCLVIDTSGLFALEPDVPLVVPGVNPQVLADYRNRNIVAVADSMVSQLLTAIKPLTEQAGLSRLHVTTLMS
VSARGKAAVDDLAGQSARLLNGIPAEAGVFAKQLAFNLLPLLADEQGSVREERLIVDQVRKVLQDEGLPISVSCVQSPVF
YGHAQVVHLEALRPMSAEEARSELEQVDDIQLSEEDDYPTQVTEASGSDALSVGCLRNDYGIPEILQFWSVADNVRFGGA
LMAIETAERLVQEQMY
>Mature_335_residues
SDGWNIALLGATGAVGEALLELLQERQFPVGELYPLASERSAGATVRFNGKSVLVQNAEEFDWSQAQLAFFVAGTEASAR
YAEEAGNMGCLVIDTSGLFALEPDVPLVVPGVNPQVLADYRNRNIVAVADSMVSQLLTAIKPLTEQAGLSRLHVTTLMSV
SARGKAAVDDLAGQSARLLNGIPAEAGVFAKQLAFNLLPLLADEQGSVREERLIVDQVRKVLQDEGLPISVSCVQSPVFY
GHAQVVHLEALRPMSAEEARSELEQVDDIQLSEEDDYPTQVTEASGSDALSVGCLRNDYGIPEILQFWSVADNVRFGGAL
MAIETAERLVQEQMY

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=337, Percent_Identity=71.2166172106825, Blast_Score=491, Evalue=1e-140,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012080
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: 1.2.1.11

Molecular weight: Translated: 36192; Mature: 36061

Theoretical pI: Translated: 4.09; Mature: 4.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDGWNIALLGATGAVGEALLELLQERQFPVGELYPLASERSAGATVRFNGKSVLVQNAE
CCCCCEEEEEECCCHHHHHHHHHHHHCCCCCHHCCCCCCCCCCCCEEEECCCEEEEECCH
EFDWSQAQLAFFVAGTEASARYAEEAGNMGCLVIDTSGLFALEPDVPLVVPGVNPQVLAD
HCCCCCEEEEEEEECCCHHHHHHHHCCCCEEEEEECCCEEEECCCCCEEECCCCHHHHHH
YRNRNIVAVADSMVSQLLTAIKPLTEQAGLSRLHVTTLMSVSARGKAAVDDLAGQSARLL
CCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHCCCHHHHH
NGIPAEAGVFAKQLAFNLLPLLADEQGSVREERLIVDQVRKVLQDEGLPISVSCVQSPVF
CCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEHHHCCCEE
YGHAQVVHLEALRPMSAEEARSELEQVDDIQLSEEDDYPTQVTEASGSDALSVGCLRNDY
ECCEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCEEEEEECCCC
GIPEILQFWSVADNVRFGGALMAIETAERLVQEQMY
CCHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHCC
>Mature Secondary Structure 
SDGWNIALLGATGAVGEALLELLQERQFPVGELYPLASERSAGATVRFNGKSVLVQNAE
CCCCEEEEEECCCHHHHHHHHHHHHCCCCCHHCCCCCCCCCCCCEEEECCCEEEEECCH
EFDWSQAQLAFFVAGTEASARYAEEAGNMGCLVIDTSGLFALEPDVPLVVPGVNPQVLAD
HCCCCCEEEEEEEECCCHHHHHHHHCCCCEEEEEECCCEEEECCCCCEEECCCCHHHHHH
YRNRNIVAVADSMVSQLLTAIKPLTEQAGLSRLHVTTLMSVSARGKAAVDDLAGQSARLL
CCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHCCCHHHHH
NGIPAEAGVFAKQLAFNLLPLLADEQGSVREERLIVDQVRKVLQDEGLPISVSCVQSPVF
CCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEHHHCCCEE
YGHAQVVHLEALRPMSAEEARSELEQVDDIQLSEEDDYPTQVTEASGSDALSVGCLRNDY
ECCEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCEEEEEECCCC
GIPEILQFWSVADNVRFGGALMAIETAERLVQEQMY
CCHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate 4-semialdehyde; phosphate; NADP+

Specific reaction: L-aspartate 4-semialdehyde + phosphate + NADP+ = L-4-aspartyl phosphate + NADPH + H+

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2991861; 9205837; 9278503; 3029016; 2681152 [H]