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The map label for this gene is cheA [H]

Identifier: 157371225

GI number: 157371225

Start: 3282917

End: 3284884

Strand: Reverse

Name: cheA [H]

Synonym: Spro_2985

Alternate gene names: 157371225

Gene position: 3284884-3282917 (Counterclockwise)

Preceding gene: 157371226

Following gene: 157371224

Centisome position: 60.29

GC content: 58.49

Gene sequence:

>1968_bases
ATGGATATTAGTGCGTTTTATCAGACCTTTTTTGATGAAGCAGACGAGTTGCTGGCCGATATGGAGCAACACCTGCTGGA
GTTGGATCCGCTGGCACCGGACATTGAGCCGCTGAACGCCATTTTCCGCGCAGCGCACTCTATAAAGGGCGGGGCGGCTA
CCTTTGGTTTTACGGTACTGCAGGAAACCACCCATCTGCTGGAGAACCTGCTCGATGGTGCGCGGCGTCAGGAAATGAGC
CTGAGCACCGAGATTATCAACCTGTTTCTGGAAACCAAAGACATTATGCAGGAGCAACTGGACGCCTATAAGACGTCACA
AAAACCTGACGCCGACAGTTTTGAATACATCTGCCAGGCGTTGCGGCAGCTGGCGTTGGACGCACAGCAACAGGATGCCC
CCGCAGCGCATCCGGCCACGGAACATGCCGTCGCGGTACCTGCGGCGATCGAAGGCGGGATGCGAATTTGCCTGAGTGGC
CTCAAATCCAGCGAAGTCCCGCTGATGCTTGAAGAACTGGGGAATCTGGGCGAGGTGAAAAACCCGCAGCAGACCGAAAA
CAGTCTGGAAGTGACGCTGCTGACCTCCGCCAGCGAAGATGACATCAGCGCGGTACTCTGTTTTGTACTGGAGCCGGAGC
AAATCAGCTTCGCTACGCCGCCGCAGGCCGAAGTCGCGCCTGCCGCACCGGTACAGTCAGCGCCTGTCGTCGCGACAGCA
GCGGTGGTCAAACCGGCACCTGCGGCTGTCGAAGTTGCCAAACCACGGGCCAAGGCCAGCGAATCCACCAGTATCCGCGT
CGCGGTAGAGAAAGTGGACCAGTTAATTAACCTGGTCGGTGAGCTGGTGATCACCCAATCGATGCTGGCGCAGCGTTCGG
GCAGCCTGGATCCGGTGAATCACGGCGACTTGCTCAACAGCATGAGCCAGTTGGAACGCAATGCGCGCGACCTGCAAGAG
TCAGTGATGTCGATTCGCATGATGCCGATGGAGTACGTGTTCAGCCGCTTCCCGCGGTTGGTGCGCGATCTGGCCGGCAA
GCTGAATAAACAGGTGGAGTTGCAGCTGCAGGGCAGTTCTACCGAACTGGACAAGAGCCTGATCGAACGCATCATCGACC
CCTTGACCCACCTGGTGCGCAACAGCCTGGATCACGGCATTGAAGATCCCGATACGCGCGTCGCCGCCGGCAAATCGGCG
GTGGGTAATCTGATCCTGTCGGCGGAACACCAGGGCGGCAATATCTGCATCGAGGTGACCGACGACGGCGCCGGTCTGAA
CCGCGAGAAAATTCTCGCCAAGGCGGCCTCGCAGGGGCTGGCGGTCAGTGACAGCATGAGCGATGAAGACGTCGGTATGT
TGATCTTTGCTCCGGGCTTTTCCACTGCCGAACAGGTCACCGATGTGTCCGGGCGTGGCGTCGGCATGGACGTGGTGAAG
CGAAATATTCAGGAGATGGGTGGGCATGTAGAAATCCATTCTCAGGCAGGCAAGGGGACCGCGATCCGCATCCTGCTGCC
GTTGACGCTGGCGATCCTCGACGGTATGTCGGTCAAGGTGAACGACGAAGTGTTTATTCTGCCGCTCAACGCGGTAATGG
AATCACTGCAGCCGCAGGCCGAAGACCTGCATCCATTGGCCGGTGGCGAGCGAGTGTTGCAGGTGCGCGGTGAATATCTG
CCGCTGGTGGAACTGTTCCGGGTGTTCGAAGTGGCAGGCGCCAAAACCGATGCCACTCAGGGCATTGTGGTGATCCTGCA
AAGTGCCGGTCGTCGCTATGCGTTGCTGGTAGATCAATTGGTCGGTCAGCATCAGGTCGTGGTGAAGAATCTGGAAAGCA
ACTATCGCAAAGTGCCGGGTATTTCCGCCGCCACTATTCTCGGCGATGGCAGCGTGGCGCTGATTGTCGATGTCTCGGCG
CTGCAAACGCTGAACCGTGAACAGCGTCAGACCGACGCGGCCGCATAA

Upstream 100 bases:

>100_bases
CCGGCGGCGACGGCTCCGGCCACCCTCATTGCACCGGAGCAGCCGGCGGCTGACCCAGTACCGACTAACAGCGACTCACA
GCAGAGGTGATCCCGTGAGC

Downstream 100 bases:

>100_bases
TAATTAATCTATTGATTTGAAGGGTGAATGACATGGCAGGACTGGCAACCGTCAGCAAACTGGCTGGCGAAACGGTAGGG
CAAGAATTCCTGATTTTTAC

Product: chemotaxis protein CheA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 655; Mature: 655

Protein sequence:

>655_residues
MDISAFYQTFFDEADELLADMEQHLLELDPLAPDIEPLNAIFRAAHSIKGGAATFGFTVLQETTHLLENLLDGARRQEMS
LSTEIINLFLETKDIMQEQLDAYKTSQKPDADSFEYICQALRQLALDAQQQDAPAAHPATEHAVAVPAAIEGGMRICLSG
LKSSEVPLMLEELGNLGEVKNPQQTENSLEVTLLTSASEDDISAVLCFVLEPEQISFATPPQAEVAPAAPVQSAPVVATA
AVVKPAPAAVEVAKPRAKASESTSIRVAVEKVDQLINLVGELVITQSMLAQRSGSLDPVNHGDLLNSMSQLERNARDLQE
SVMSIRMMPMEYVFSRFPRLVRDLAGKLNKQVELQLQGSSTELDKSLIERIIDPLTHLVRNSLDHGIEDPDTRVAAGKSA
VGNLILSAEHQGGNICIEVTDDGAGLNREKILAKAASQGLAVSDSMSDEDVGMLIFAPGFSTAEQVTDVSGRGVGMDVVK
RNIQEMGGHVEIHSQAGKGTAIRILLPLTLAILDGMSVKVNDEVFILPLNAVMESLQPQAEDLHPLAGGERVLQVRGEYL
PLVELFRVFEVAGAKTDATQGIVVILQSAGRRYALLVDQLVGQHQVVVKNLESNYRKVPGISAATILGDGSVALIVDVSA
LQTLNREQRQTDAAA

Sequences:

>Translated_655_residues
MDISAFYQTFFDEADELLADMEQHLLELDPLAPDIEPLNAIFRAAHSIKGGAATFGFTVLQETTHLLENLLDGARRQEMS
LSTEIINLFLETKDIMQEQLDAYKTSQKPDADSFEYICQALRQLALDAQQQDAPAAHPATEHAVAVPAAIEGGMRICLSG
LKSSEVPLMLEELGNLGEVKNPQQTENSLEVTLLTSASEDDISAVLCFVLEPEQISFATPPQAEVAPAAPVQSAPVVATA
AVVKPAPAAVEVAKPRAKASESTSIRVAVEKVDQLINLVGELVITQSMLAQRSGSLDPVNHGDLLNSMSQLERNARDLQE
SVMSIRMMPMEYVFSRFPRLVRDLAGKLNKQVELQLQGSSTELDKSLIERIIDPLTHLVRNSLDHGIEDPDTRVAAGKSA
VGNLILSAEHQGGNICIEVTDDGAGLNREKILAKAASQGLAVSDSMSDEDVGMLIFAPGFSTAEQVTDVSGRGVGMDVVK
RNIQEMGGHVEIHSQAGKGTAIRILLPLTLAILDGMSVKVNDEVFILPLNAVMESLQPQAEDLHPLAGGERVLQVRGEYL
PLVELFRVFEVAGAKTDATQGIVVILQSAGRRYALLVDQLVGQHQVVVKNLESNYRKVPGISAATILGDGSVALIVDVSA
LQTLNREQRQTDAAA
>Mature_655_residues
MDISAFYQTFFDEADELLADMEQHLLELDPLAPDIEPLNAIFRAAHSIKGGAATFGFTVLQETTHLLENLLDGARRQEMS
LSTEIINLFLETKDIMQEQLDAYKTSQKPDADSFEYICQALRQLALDAQQQDAPAAHPATEHAVAVPAAIEGGMRICLSG
LKSSEVPLMLEELGNLGEVKNPQQTENSLEVTLLTSASEDDISAVLCFVLEPEQISFATPPQAEVAPAAPVQSAPVVATA
AVVKPAPAAVEVAKPRAKASESTSIRVAVEKVDQLINLVGELVITQSMLAQRSGSLDPVNHGDLLNSMSQLERNARDLQE
SVMSIRMMPMEYVFSRFPRLVRDLAGKLNKQVELQLQGSSTELDKSLIERIIDPLTHLVRNSLDHGIEDPDTRVAAGKSA
VGNLILSAEHQGGNICIEVTDDGAGLNREKILAKAASQGLAVSDSMSDEDVGMLIFAPGFSTAEQVTDVSGRGVGMDVVK
RNIQEMGGHVEIHSQAGKGTAIRILLPLTLAILDGMSVKVNDEVFILPLNAVMESLQPQAEDLHPLAGGERVLQVRGEYL
PLVELFRVFEVAGAKTDATQGIVVILQSAGRRYALLVDQLVGQHQVVVKNLESNYRKVPGISAATILGDGSVALIVDVSA
LQTLNREQRQTDAAA

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=659, Percent_Identity=75.8725341426404, Blast_Score=978, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR015162
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01584 CheW; PF09078 CheY-binding; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 70493; Mature: 70493

Theoretical pI: Translated: 4.39; Mature: 4.39

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS00039 DEAD_ATP_HELICASE ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDISAFYQTFFDEADELLADMEQHLLELDPLAPDIEPLNAIFRAAHSIKGGAATFGFTVL
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHH
QETTHLLENLLDGARRQEMSLSTEIINLFLETKDIMQEQLDAYKTSQKPDADSFEYICQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
LRQLALDAQQQDAPAAHPATEHAVAVPAAIEGGMRICLSGLKSSEVPLMLEELGNLGEVK
HHHHHCCCHHCCCCCCCCCCCCCEECHHHHHCCHHHHHHCCCCCCCCHHHHHCCCCCCCC
NPQQTENSLEVTLLTSASEDDISAVLCFVLEPEQISFATPPQAEVAPAAPVQSAPVVATA
CCCCCCCCEEEEEEECCCCCCHHHEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
AVVKPAPAAVEVAKPRAKASESTSIRVAVEKVDQLINLVGELVITQSMLAQRSGSLDPVN
HHHCCCCCHHHHCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
HGDLLNSMSQLERNARDLQESVMSIRMMPMEYVFSRFPRLVRDLAGKLNKQVELQLQGSS
CHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCC
TELDKSLIERIIDPLTHLVRNSLDHGIEDPDTRVAAGKSAVGNLILSAEHQGGNICIEVT
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCHHHHCCEEEEEECCCCEEEEEEC
DDGAGLNREKILAKAASQGLAVSDSMSDEDVGMLIFAPGFSTAEQVTDVSGRGVGMDVVK
CCCCCCCHHHHHHHHHHCCCEECCCCCCCCCCEEEEECCCCCHHHHHCCCCCCCCHHHHH
RNIQEMGGHVEIHSQAGKGTAIRILLPLTLAILDGMSVKVNDEVFILPLNAVMESLQPQA
HHHHHCCCEEEEECCCCCCCEEEEHHHHHHHHHCCCEEEECCCEEEEEHHHHHHHCCCCH
EDLHPLAGGERVLQVRGEYLPLVELFRVFEVAGAKTDATQGIVVILQSAGRRYALLVDQL
HHCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCHHHHHHHH
VGQHQVVVKNLESNYRKVPGISAATILGDGSVALIVDVSALQTLNREQRQTDAAA
HCCHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEEHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDISAFYQTFFDEADELLADMEQHLLELDPLAPDIEPLNAIFRAAHSIKGGAATFGFTVL
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHH
QETTHLLENLLDGARRQEMSLSTEIINLFLETKDIMQEQLDAYKTSQKPDADSFEYICQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
LRQLALDAQQQDAPAAHPATEHAVAVPAAIEGGMRICLSGLKSSEVPLMLEELGNLGEVK
HHHHHCCCHHCCCCCCCCCCCCCEECHHHHHCCHHHHHHCCCCCCCCHHHHHCCCCCCCC
NPQQTENSLEVTLLTSASEDDISAVLCFVLEPEQISFATPPQAEVAPAAPVQSAPVVATA
CCCCCCCCEEEEEEECCCCCCHHHEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
AVVKPAPAAVEVAKPRAKASESTSIRVAVEKVDQLINLVGELVITQSMLAQRSGSLDPVN
HHHCCCCCHHHHCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
HGDLLNSMSQLERNARDLQESVMSIRMMPMEYVFSRFPRLVRDLAGKLNKQVELQLQGSS
CHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCC
TELDKSLIERIIDPLTHLVRNSLDHGIEDPDTRVAAGKSAVGNLILSAEHQGGNICIEVT
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCHHHHCCEEEEEECCCCEEEEEEC
DDGAGLNREKILAKAASQGLAVSDSMSDEDVGMLIFAPGFSTAEQVTDVSGRGVGMDVVK
CCCCCCCHHHHHHHHHHCCCEECCCCCCCCCCEEEEECCCCCHHHHHCCCCCCCCHHHHH
RNIQEMGGHVEIHSQAGKGTAIRILLPLTLAILDGMSVKVNDEVFILPLNAVMESLQPQA
HHHHHCCCEEEEECCCCCCCEEEEHHHHHHHHHCCCEEEECCCEEEEEHHHHHHHCCCCH
EDLHPLAGGERVLQVRGEYLPLVELFRVFEVAGAKTDATQGIVVILQSAGRRYALLVDQL
HHCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCHHHHHHHH
VGQHQVVVKNLESNYRKVPGISAATILGDGSVALIVDVSALQTLNREQRQTDAAA
HCCHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEEHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2002011; 9097040; 9278503; 3510184; 2832069; 2068106; 8555213; 8639521; 9020767; 9437425; 9636149 [H]