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The map label for this gene is flhA [H]

Identifier: 157371216

GI number: 157371216

Start: 3271948

End: 3274026

Strand: Reverse

Name: flhA [H]

Synonym: Spro_2976

Alternate gene names: 157371216

Gene position: 3274026-3271948 (Counterclockwise)

Preceding gene: 157371217

Following gene: 157371215

Centisome position: 60.09

GC content: 58.1

Gene sequence:

>2079_bases
ATGGCTAATTTGGCCGCCCTGCTTCGTTTGCCGGGCAGTTTTAAAGATACGCAGTGGCAGGTATTGGCCGGCCCGATACT
GATTCTGATGATCCTGTCGATGATGGTGCTGCCGTTGCCGGCATTTATCCTCGATCTGTTGTTCACCTTCAATATTGCCT
TGTCGATCATGGTGCTGCTGGTAGCGATGTTTACCCAGCGCACGCTGGAATTTGCCGCATTCCCTACCATCTTGCTGTTC
TCGACCTTATTGCGCCTGTCGCTCAACGTAGCCTCGACGCGCATCATCCTGATGGAAGGGCATACCGGTTCCGCCGCTGC
CGGGCGTGTGGTGGAAGCCTTTGGCCACTTCCTGGTGGGCGGTAACTTCGCCATCGGTATTGTGGTGTTTATCATTCTGG
TGCTGATCAACTTTATGGTTATCACCAAGGGTGCCGGGCGTATCGCCGAAGTAGGCGCGCGTTTTGTACTGGACGGCATG
CCGGGTAAGCAGATGGCGATCGATGCCGATCTCAACGCCGGTTTGATCGGTGAAGAAGAAGCGAAAAAACGCCGTTCTGA
AGTTACGCAGGAGGCCGACTTCTACGGCTCGATGGACGGTGCCAGTAAGTTCGTTCGTGGCGATGCGGTCGCCGGCCTGA
TGATCATGATACTGAACGTGGTCGGTGGTCTGCTGGTCGGGGTGATCCAGCACGGGATGGAAGTGGGTACGGCAGCGGAA
ACCTATACCTTGCTGACTATCGGTGACGGCCTGGTGGCGCAGATCCCGGCGTTGGTTATTTCGACTGCGGCCGGCGTTAT
CGTGACCCGCGTGGCGACCGATCAGGATGTCGGCGAGCAAATGGTCGGCCAACTGTTCAACAATCCGCGCGTAATGTTAC
TCAGCGCCGCCGTGCTCGGCCTGCTTGGCATGGTGCCGGGGATGCCGAACTTGGTCTTCCTGCTGTTCACCGCCGCTCTG
TTGGGGTTGGCCTGGTGGCTGCGTGGGCGCGATCAGCAAGCTCCCAAAGAGCAGGAAGCGCCGATAACGCAGGACAACCC
GCAGGCGGTAGAAGCCAGTTGGTCTGATGTGCAGTTGGAAGATCCGCTGGGGATGGAGGTCGGTTACCGATTGATCCCGA
TGGTAGATTTCCAGCAGAACGGCGAACTGCTTGGCCGTATCCGCGGCATCCGTAAAAAGTTCGCGCAGGAGATGGGTTAC
CTGCCGCCGGTGGTACACATTCGCGACAACCTCGAATTACCGCCAGCCAGTTACCGCATCCTGATGAAGGGAGTAGAAAT
CGGCAGCGGCGAAGCCCAACCGGGACGTTGGCTGGCGATTAACCCAGGCAACGCGGTGGGTGAATTGGCGGGGGATAAAA
CCACCGACCCGGCGTTTGGGCTGGAAGCGGTATGGATTGACAGCGCGCTGCGTGAGCAGGCGCAGATCCAGGGCTTTACC
GTGGTAGAAGCCAGCACCGTGGTGGCGACCCATCTGAATCATCTGATTGGTCAATTCGCCAGCGAGCTGTTTGGTCGACA
GGAAACGCAGCAGCTGTTGGATCGTGTAGCGCAGGACATGCCGAAACTGACTGAAGATTTCGTGCCGGGCGTGGTGACGC
TGACCACGTTGCACAAGGTGTTGCAGAACCTGCTGACGGAGCGAGTTTCGATCCGCGATATGCGCACCATTATTGAAACT
CTGGCGGAACATGCACCGACGCAAACCGATCCCTATGAACTGACCACCGTGGTGCGGGTCGCGTTGGGACGAGCCATCAC
CCAGCAGTGGTTCCCGGGCAACGGTGAAATTCAGGTCATTGGTCTGGACACCCAACTTGAGCGTTTGTTATTGCAGGCGT
TGCAGGGCGGTGGCGGTCTGGAACCGGGGTTGGCGGATCGTCTGCTGGATCAGGCCAAACAGGCGTTGCAACGTCAGGAA
ATGTTAAGTGCGCCGCCGGTGCTGTTGGTGAACCATGCGCTGCGGGCCTTGCTGGCACGCTTCCTGCGCCGTAGTTTGCC
GCAACTGGTGGTGCTGTCGAATCTGGAAATCAACGACGACCGTCAGATCCGCATGACTTCGACCATTGGGGTCGCATAA

Upstream 100 bases:

>100_bases
CAGCTAAGACGCTGGCGGCGCGAAGGTGGGCTGATCCCGAAAAAACCTGAACGTTTACCGGTGCCGGAAGCACTGGATTT
TGCTGGAGAAAGTGACACTA

Downstream 100 bases:

>100_bases
TGAAATACAGCATGGCGATAATCTGCCTGTTGGCTCCGCTGAGCCTGCAGGCGGCGTCCGGTTCCTGGGTAGCCGACAGC
GTGGGTGCCACGCTGGAACA

Product: flagellar biosynthesis protein FlhA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 692; Mature: 691

Protein sequence:

>692_residues
MANLAALLRLPGSFKDTQWQVLAGPILILMILSMMVLPLPAFILDLLFTFNIALSIMVLLVAMFTQRTLEFAAFPTILLF
STLLRLSLNVASTRIILMEGHTGSAAAGRVVEAFGHFLVGGNFAIGIVVFIILVLINFMVITKGAGRIAEVGARFVLDGM
PGKQMAIDADLNAGLIGEEEAKKRRSEVTQEADFYGSMDGASKFVRGDAVAGLMIMILNVVGGLLVGVIQHGMEVGTAAE
TYTLLTIGDGLVAQIPALVISTAAGVIVTRVATDQDVGEQMVGQLFNNPRVMLLSAAVLGLLGMVPGMPNLVFLLFTAAL
LGLAWWLRGRDQQAPKEQEAPITQDNPQAVEASWSDVQLEDPLGMEVGYRLIPMVDFQQNGELLGRIRGIRKKFAQEMGY
LPPVVHIRDNLELPPASYRILMKGVEIGSGEAQPGRWLAINPGNAVGELAGDKTTDPAFGLEAVWIDSALREQAQIQGFT
VVEASTVVATHLNHLIGQFASELFGRQETQQLLDRVAQDMPKLTEDFVPGVVTLTTLHKVLQNLLTERVSIRDMRTIIET
LAEHAPTQTDPYELTTVVRVALGRAITQQWFPGNGEIQVIGLDTQLERLLLQALQGGGGLEPGLADRLLDQAKQALQRQE
MLSAPPVLLVNHALRALLARFLRRSLPQLVVLSNLEINDDRQIRMTSTIGVA

Sequences:

>Translated_692_residues
MANLAALLRLPGSFKDTQWQVLAGPILILMILSMMVLPLPAFILDLLFTFNIALSIMVLLVAMFTQRTLEFAAFPTILLF
STLLRLSLNVASTRIILMEGHTGSAAAGRVVEAFGHFLVGGNFAIGIVVFIILVLINFMVITKGAGRIAEVGARFVLDGM
PGKQMAIDADLNAGLIGEEEAKKRRSEVTQEADFYGSMDGASKFVRGDAVAGLMIMILNVVGGLLVGVIQHGMEVGTAAE
TYTLLTIGDGLVAQIPALVISTAAGVIVTRVATDQDVGEQMVGQLFNNPRVMLLSAAVLGLLGMVPGMPNLVFLLFTAAL
LGLAWWLRGRDQQAPKEQEAPITQDNPQAVEASWSDVQLEDPLGMEVGYRLIPMVDFQQNGELLGRIRGIRKKFAQEMGY
LPPVVHIRDNLELPPASYRILMKGVEIGSGEAQPGRWLAINPGNAVGELAGDKTTDPAFGLEAVWIDSALREQAQIQGFT
VVEASTVVATHLNHLIGQFASELFGRQETQQLLDRVAQDMPKLTEDFVPGVVTLTTLHKVLQNLLTERVSIRDMRTIIET
LAEHAPTQTDPYELTTVVRVALGRAITQQWFPGNGEIQVIGLDTQLERLLLQALQGGGGLEPGLADRLLDQAKQALQRQE
MLSAPPVLLVNHALRALLARFLRRSLPQLVVLSNLEINDDRQIRMTSTIGVA
>Mature_691_residues
ANLAALLRLPGSFKDTQWQVLAGPILILMILSMMVLPLPAFILDLLFTFNIALSIMVLLVAMFTQRTLEFAAFPTILLFS
TLLRLSLNVASTRIILMEGHTGSAAAGRVVEAFGHFLVGGNFAIGIVVFIILVLINFMVITKGAGRIAEVGARFVLDGMP
GKQMAIDADLNAGLIGEEEAKKRRSEVTQEADFYGSMDGASKFVRGDAVAGLMIMILNVVGGLLVGVIQHGMEVGTAAET
YTLLTIGDGLVAQIPALVISTAAGVIVTRVATDQDVGEQMVGQLFNNPRVMLLSAAVLGLLGMVPGMPNLVFLLFTAALL
GLAWWLRGRDQQAPKEQEAPITQDNPQAVEASWSDVQLEDPLGMEVGYRLIPMVDFQQNGELLGRIRGIRKKFAQEMGYL
PPVVHIRDNLELPPASYRILMKGVEIGSGEAQPGRWLAINPGNAVGELAGDKTTDPAFGLEAVWIDSALREQAQIQGFTV
VEASTVVATHLNHLIGQFASELFGRQETQQLLDRVAQDMPKLTEDFVPGVVTLTTLHKVLQNLLTERVSIRDMRTIIETL
AEHAPTQTDPYELTTVVRVALGRAITQQWFPGNGEIQVIGLDTQLERLLLQALQGGGGLEPGLADRLLDQAKQALQRQEM
LSAPPVLLVNHALRALLARFLRRSLPQLVVLSNLEINDDRQIRMTSTIGVA

Specific function: Required for formation of the rod structure of the flagellar apparatus. Together with fliI and fliH, may constitute the export apparatus of flagellin [H]

COG id: COG1298

COG function: function code NU; Flagellar biosynthesis pathway, component FlhA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family [H]

Homologues:

Organism=Escherichia coli, GI1788187, Length=690, Percent_Identity=85.072463768116, Blast_Score=1170, Evalue=0.0,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006301
- InterPro:   IPR001712 [H]

Pfam domain/function: PF00771 FHIPEP [H]

EC number: NA

Molecular weight: Translated: 75033; Mature: 74902

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS00994 FHIPEP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANLAALLRLPGSFKDTQWQVLAGPILILMILSMMVLPLPAFILDLLFTFNIALSIMVLL
CCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAMFTQRTLEFAAFPTILLFSTLLRLSLNVASTRIILMEGHTGSAAAGRVVEAFGHFLVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHHHHCC
GNFAIGIVVFIILVLINFMVITKGAGRIAEVGARFVLDGMPGKQMAIDADLNAGLIGEEE
CCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCHHHEECCCCCCCEEEECCCCCCCCCCHH
AKKRRSEVTQEADFYGSMDGASKFVRGDAVAGLMIMILNVVGGLLVGVIQHGMEVGTAAE
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
TYTLLTIGDGLVAQIPALVISTAAGVIVTRVATDQDVGEQMVGQLFNNPRVMLLSAAVLG
EEEEEEECCCHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHH
LLGMVPGMPNLVFLLFTAALLGLAWWLRGRDQQAPKEQEAPITQDNPQAVEASWSDVQLE
HHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCCCCCCHHCCCCCCEEEC
DPLGMEVGYRLIPMVDFQQNGELLGRIRGIRKKFAQEMGYLPPVVHIRDNLELPPASYRI
CCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHH
LMKGVEIGSGEAQPGRWLAINPGNAVGELAGDKTTDPAFGLEAVWIDSALREQAQIQGFT
HHCCCCCCCCCCCCCCEEEECCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEE
VVEASTVVATHLNHLIGQFASELFGRQETQQLLDRVAQDMPKLTEDFVPGVVTLTTLHKV
EEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
LQNLLTERVSIRDMRTIIETLAEHAPTQTDPYELTTVVRVALGRAITQQWFPGNGEIQVI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
GLDTQLERLLLQALQGGGGLEPGLADRLLDQAKQALQRQEMLSAPPVLLVNHALRALLAR
ECCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
FLRRSLPQLVVLSNLEINDDRQIRMTSTIGVA
HHHHCCCCEEEECCCEECCCCCEEEECCCCCC
>Mature Secondary Structure 
ANLAALLRLPGSFKDTQWQVLAGPILILMILSMMVLPLPAFILDLLFTFNIALSIMVLL
CCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAMFTQRTLEFAAFPTILLFSTLLRLSLNVASTRIILMEGHTGSAAAGRVVEAFGHFLVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHHHHCC
GNFAIGIVVFIILVLINFMVITKGAGRIAEVGARFVLDGMPGKQMAIDADLNAGLIGEEE
CCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCHHHEECCCCCCCEEEECCCCCCCCCCHH
AKKRRSEVTQEADFYGSMDGASKFVRGDAVAGLMIMILNVVGGLLVGVIQHGMEVGTAAE
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
TYTLLTIGDGLVAQIPALVISTAAGVIVTRVATDQDVGEQMVGQLFNNPRVMLLSAAVLG
EEEEEEECCCHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHCCCHHHHHHHHHHH
LLGMVPGMPNLVFLLFTAALLGLAWWLRGRDQQAPKEQEAPITQDNPQAVEASWSDVQLE
HHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCCCCCCHHCCCCCCEEEC
DPLGMEVGYRLIPMVDFQQNGELLGRIRGIRKKFAQEMGYLPPVVHIRDNLELPPASYRI
CCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHH
LMKGVEIGSGEAQPGRWLAINPGNAVGELAGDKTTDPAFGLEAVWIDSALREQAQIQGFT
HHCCCCCCCCCCCCCCEEEECCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEE
VVEASTVVATHLNHLIGQFASELFGRQETQQLLDRVAQDMPKLTEDFVPGVVTLTTLHKV
EEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
LQNLLTERVSIRDMRTIIETLAEHAPTQTDPYELTTVVRVALGRAITQQWFPGNGEIQVI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
GLDTQLERLLLQALQGGGGLEPGLADRLLDQAKQALQRQEMLSAPPVLLVNHALRALLAR
ECCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
FLRRSLPQLVVLSNLEINDDRQIRMTSTIGVA
HHHHCCCCEEEECCCEECCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9387224 [H]