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The map label for this gene is dcyD

Identifier: 157371177

GI number: 157371177

Start: 3237461

End: 3238453

Strand: Reverse

Name: dcyD

Synonym: Spro_2937

Alternate gene names: 157371177

Gene position: 3238453-3237461 (Counterclockwise)

Preceding gene: 157371178

Following gene: 157371176

Centisome position: 59.43

GC content: 57.8

Gene sequence:

>993_bases
GTGAATCTGCAACAAAAATTGGCGCAGTTCCCGCGTCTCGATTTAGTCGGTTCTGCCACACCGCTCGAAAAACTGTCTCG
CCTCTCAGACTACCTTGGCCGTGAAATTTACATCAAACGTGACGACGTCACGCCGATGGCGATGGGCGGTAACAAACTGA
GAAAGCTTGAGTTTTTGGCTGCAGATGCGCTGCGGCAGGGAGCCGATACGCTGGTCACCGCCGGTGCCATCCAATCCAAC
CATGTGCGCCAAACGGCGGCGGTGGCGGCCAAGTTGGGTCTGCACTGTGTGGCGTTGCTGGAAAATCCGATCGACACCCA
GGAAGAAAATTATCTGACCAACGGCAACCGCCTGCTGCTCGGGCTGTTCAACGCGCAGGTGGAAATGTGCGAAGCGCTGC
ACGATCCGCAGCAGCAGTTGGCCGATCTGGCTACACGCCTCGAAGCACAAGGCTTCCGACCTTATGTGGTGCCGGTAGGT
GGCTCTAATGCGCTGGGTGCATTGGGTTACGTACAGTGTGCGCTGGAAATTGCCGAGCAGAGTCAGCGCAGCAACGTCGC
TTTCAGCTCGGTAGTGGTGGCGTCTGGCAGTGCCGGGACCCATGCCGGGCTGGCGGTCGGTCTGCAGCAATTGCTGCCGG
AGACTGAGCTTGTCGGTGTGACCGTTTCACGCAAAGTTATCGACCAATTGCCCAAGGTAGAACAGATCCAAAAAGCGCTG
GCCAACAGTTTGGCTATCGACGAACTGGCACCCATCACCCTGTGGGATGATTATTTCGCACCGCAGTACGGCATGCCCAA
TGAAGAAGGGCTGGCGGCCATCCAGTTGCTGGCGCAGCAGGAAGGAGTGTTACTGGATCCGGTGTATAGCGGCAAGGCAA
TGGCTGGGCTGATAGACGGCGTAGCCCAGCAGCGTTTCCGTGATGACGGCCCGATTCTGTTCATCCACACCGGCGGTGCT
CCGGCGTTATTTGCCTACCATCCACAGGTGTGA

Upstream 100 bases:

>100_bases
GTTTCCACCGCTCTCCCATTACGAATAAAGAGTGATTATTAGGTTCACATCTGCTAAATCTATCCTTTAGCTATTGATAC
CTTATTCCCTGGGGGAAGTT

Downstream 100 bases:

>100_bases
GCGCACTTGGTTATTCCATTTTGAACTATATTTATAATGTTATATTCCTGCGTTCAAATGTTGTGGCTGTTAAAGTGCTG
ATATAAAAAAAGATAAACAA

Product: D-cysteine desulfhydrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MNLQQKLAQFPRLDLVGSATPLEKLSRLSDYLGREIYIKRDDVTPMAMGGNKLRKLEFLAADALRQGADTLVTAGAIQSN
HVRQTAAVAAKLGLHCVALLENPIDTQEENYLTNGNRLLLGLFNAQVEMCEALHDPQQQLADLATRLEAQGFRPYVVPVG
GSNALGALGYVQCALEIAEQSQRSNVAFSSVVVASGSAGTHAGLAVGLQQLLPETELVGVTVSRKVIDQLPKVEQIQKAL
ANSLAIDELAPITLWDDYFAPQYGMPNEEGLAAIQLLAQQEGVLLDPVYSGKAMAGLIDGVAQQRFRDDGPILFIHTGGA
PALFAYHPQV

Sequences:

>Translated_330_residues
MNLQQKLAQFPRLDLVGSATPLEKLSRLSDYLGREIYIKRDDVTPMAMGGNKLRKLEFLAADALRQGADTLVTAGAIQSN
HVRQTAAVAAKLGLHCVALLENPIDTQEENYLTNGNRLLLGLFNAQVEMCEALHDPQQQLADLATRLEAQGFRPYVVPVG
GSNALGALGYVQCALEIAEQSQRSNVAFSSVVVASGSAGTHAGLAVGLQQLLPETELVGVTVSRKVIDQLPKVEQIQKAL
ANSLAIDELAPITLWDDYFAPQYGMPNEEGLAAIQLLAQQEGVLLDPVYSGKAMAGLIDGVAQQRFRDDGPILFIHTGGA
PALFAYHPQV
>Mature_330_residues
MNLQQKLAQFPRLDLVGSATPLEKLSRLSDYLGREIYIKRDDVTPMAMGGNKLRKLEFLAADALRQGADTLVTAGAIQSN
HVRQTAAVAAKLGLHCVALLENPIDTQEENYLTNGNRLLLGLFNAQVEMCEALHDPQQQLADLATRLEAQGFRPYVVPVG
GSNALGALGYVQCALEIAEQSQRSNVAFSSVVVASGSAGTHAGLAVGLQQLLPETELVGVTVSRKVIDQLPKVEQIQKAL
ANSLAIDELAPITLWDDYFAPQYGMPNEEGLAAIQLLAQQEGVLLDPVYSGKAMAGLIDGVAQQRFRDDGPILFIHTGGA
PALFAYHPQV

Specific function: Catalyzes the alpha,beta-elimination reaction of D- cysteine and of several D-cysteine derivatives. It could be a defense mechanism against D-cysteine

COG id: COG2515

COG function: function code E; 1-aminocyclopropane-1-carboxylate deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ACC deaminase/D-cysteine desulfhydrase family

Homologues:

Organism=Escherichia coli, GI87082000, Length=326, Percent_Identity=76.3803680981595, Blast_Score=520, Evalue=1e-149,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DCYD_SERP5 (A8GFZ8)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001479166.1
- ProteinModelPortal:   A8GFZ8
- SMR:   A8GFZ8
- STRING:   A8GFZ8
- GeneID:   5603371
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_2937
- eggNOG:   COG2515
- HOGENOM:   HBG689308
- OMA:   LFWHTGG
- ProtClustDB:   PRK03910
- BioCyc:   SPRO399741:SPRO_2937-MONOMER
- HAMAP:   MF_01045
- InterPro:   IPR005966
- InterPro:   IPR001926
- TIGRFAMs:   TIGR01275

Pfam domain/function: PF00291 PALP; SSF53686 PyrdxlP-dep_enz_bsu

EC number: =4.4.1.15

Molecular weight: Translated: 35433; Mature: 35433

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLQQKLAQFPRLDLVGSATPLEKLSRLSDYLGREIYIKRDDVTPMAMGGNKLRKLEFLA
CCHHHHHHHCCCEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCCEECCCCHHHHHHHHH
ADALRQGADTLVTAGAIQSNHVRQTAAVAAKLGLHCVALLENPIDTQEENYLTNGNRLLL
HHHHHCCCHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCEEEE
GLFNAQVEMCEALHDPQQQLADLATRLEAQGFRPYVVPVGGSNALGALGYVQCALEIAEQ
EEHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHH
SQRSNVAFSSVVVASGSAGTHAGLAVGLQQLLPETELVGVTVSRKVIDQLPKVEQIQKAL
HHHCCCEEHEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEEHHHHHHHHCCCHHHHHHHH
ANSLAIDELAPITLWDDYFAPQYGMPNEEGLAAIQLLAQQEGVLLDPVYSGKAMAGLIDG
HHHHHHHHCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHH
VAQQRFRDDGPILFIHTGGAPALFAYHPQV
HHHHHHCCCCCEEEEECCCCCEEEEECCCC
>Mature Secondary Structure
MNLQQKLAQFPRLDLVGSATPLEKLSRLSDYLGREIYIKRDDVTPMAMGGNKLRKLEFLA
CCHHHHHHHCCCEEECCCCCHHHHHHHHHHHCCCEEEEEECCCCCEECCCCHHHHHHHHH
ADALRQGADTLVTAGAIQSNHVRQTAAVAAKLGLHCVALLENPIDTQEENYLTNGNRLLL
HHHHHCCCHHHEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCEEEE
GLFNAQVEMCEALHDPQQQLADLATRLEAQGFRPYVVPVGGSNALGALGYVQCALEIAEQ
EEHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHH
SQRSNVAFSSVVVASGSAGTHAGLAVGLQQLLPETELVGVTVSRKVIDQLPKVEQIQKAL
HHHCCCEEHEEEEECCCCCCHHHHHHHHHHHCCCCCEEEEEHHHHHHHHCCCHHHHHHHH
ANSLAIDELAPITLWDDYFAPQYGMPNEEGLAAIQLLAQQEGVLLDPVYSGKAMAGLIDG
HHHHHHHHCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCEECCCCCCHHHHHHHHH
VAQQRFRDDGPILFIHTGGAPALFAYHPQV
HHHHHHCCCCCEEEEECCCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA