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The map label for this gene is sapD [H]

Identifier: 157370872

GI number: 157370872

Start: 2896135

End: 2897127

Strand: Direct

Name: sapD [H]

Synonym: Spro_2632

Alternate gene names: 157370872

Gene position: 2896135-2897127 (Clockwise)

Preceding gene: 157370871

Following gene: 157370873

Centisome position: 53.15

GC content: 58.11

Gene sequence:

>993_bases
ATGCCATTACTTGATATCCGCAACCTGACGATTGAATTTATGACGGCCGAAGGGCCGGTCAAGGCGGTTGACCGCGTCAG
CATGACGTTGAGCGAAGGTGAAGTCCGTGGCCTGGTGGGTGAATCCGGCTCAGGCAAGAGCCTGATTGCCAAGGCAATTT
GCGGCGTCACCAAAGACAACTGGCGCGTTACCGCCGACCGTTTCCGTTTTGACGATATCGACCTGCTGCAATTGACCCCG
CGTGAACGGCGCAAACTGGTCGGGCATAACGTCTCGATGATCTTCCAGGAGCCACAGTCTTGTCTGGATCCGTCCGAAAG
CATTGGTCGCCAGTTGGCGCAGGCGATCCCTGGCTGGACCTATAAGGGCCGTTGGTGGCAACGTTTTAACTGGCGCAAGC
GCCGCGCGATTGAGCTACTGCACCGCGTGGGTATCAAGGATCACAAGGACATTATGGGCAGCTTCCCCTATGAGCTGACC
GACGGCGAATGCCAGAAAGTGATGATCGCCATCGCCCTGGCCAATCAGCCGCGCCTGCTGATTGCCGATGAACCGACCAA
CGCCATGGAACCGACCACTCAGGCGCAGATTTTCCGCCTGCTGGCGCGCCTGAACCAAAACAACAACACCACCATTTTGC
TGATCAGCCACGATTTGCAAATGATGAGTAAATGGGCGGATCGGGTCAACGTGCTGTACTGCGGCCAAACGGTGGAAAGC
GCCCAGTGCGAAGATCTGCTGGCTGCACCGCACCATCCTTACACCCAGGCGCTGATCCGCTCAATGCCTGACTTCGGCCG
CGCCTTGCCGCATAAAAGCCGGCTCAACACCCTGCCGGGAGCCATTCCGTCGCTGGAGCATTTACCTATCGGTTGCCGCC
TGGGGCCGCGTTGCCCTTACGCACAGAAAAAGTGCATTGAGACACCCCGCCTGCGCCCGGTGAAAAACCACCTGTTCGCC
TGCCACTTCCCGCTGAACATGGAGGAGCAATAA

Upstream 100 bases:

>100_bases
GGACGGTGATGCTGCCCGGTGCCGCGATCCTGATCAGCGTGCTGTTGGTTAACCTGTTGGGCGACGGTATGCGCCGCGCA
ATCAATACGGGGGTGGAATA

Downstream 100 bases:

>100_bases
CATGGAAACGCTGTTGGAAGTGCGCAATCTGAGCAAAACCTACCGCTACCGTACCGGGCTGTTTCGCCGCCAGCACGTTG
AGGCGGTGAAATCGGTCAGT

Product: oligopeptide/dipeptide ABC transporter ATPase

Products: ADP; phosphate; peptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 330; Mature: 329

Protein sequence:

>330_residues
MPLLDIRNLTIEFMTAEGPVKAVDRVSMTLSEGEVRGLVGESGSGKSLIAKAICGVTKDNWRVTADRFRFDDIDLLQLTP
RERRKLVGHNVSMIFQEPQSCLDPSESIGRQLAQAIPGWTYKGRWWQRFNWRKRRAIELLHRVGIKDHKDIMGSFPYELT
DGECQKVMIAIALANQPRLLIADEPTNAMEPTTQAQIFRLLARLNQNNNTTILLISHDLQMMSKWADRVNVLYCGQTVES
AQCEDLLAAPHHPYTQALIRSMPDFGRALPHKSRLNTLPGAIPSLEHLPIGCRLGPRCPYAQKKCIETPRLRPVKNHLFA
CHFPLNMEEQ

Sequences:

>Translated_330_residues
MPLLDIRNLTIEFMTAEGPVKAVDRVSMTLSEGEVRGLVGESGSGKSLIAKAICGVTKDNWRVTADRFRFDDIDLLQLTP
RERRKLVGHNVSMIFQEPQSCLDPSESIGRQLAQAIPGWTYKGRWWQRFNWRKRRAIELLHRVGIKDHKDIMGSFPYELT
DGECQKVMIAIALANQPRLLIADEPTNAMEPTTQAQIFRLLARLNQNNNTTILLISHDLQMMSKWADRVNVLYCGQTVES
AQCEDLLAAPHHPYTQALIRSMPDFGRALPHKSRLNTLPGAIPSLEHLPIGCRLGPRCPYAQKKCIETPRLRPVKNHLFA
CHFPLNMEEQ
>Mature_329_residues
PLLDIRNLTIEFMTAEGPVKAVDRVSMTLSEGEVRGLVGESGSGKSLIAKAICGVTKDNWRVTADRFRFDDIDLLQLTPR
ERRKLVGHNVSMIFQEPQSCLDPSESIGRQLAQAIPGWTYKGRWWQRFNWRKRRAIELLHRVGIKDHKDIMGSFPYELTD
GECQKVMIAIALANQPRLLIADEPTNAMEPTTQAQIFRLLARLNQNNNTTILLISHDLQMMSKWADRVNVLYCGQTVESA
QCEDLLAAPHHPYTQALIRSMPDFGRALPHKSRLNTLPGAIPSLEHLPIGCRLGPRCPYAQKKCIETPRLRPVKNHLFAC
HFPLNMEEQ

Specific function: Involved in a peptide intake transport system that plays a role in the resistance to antimicrobial peptides [H]

COG id: COG4170

COG function: function code V; ABC-type antimicrobial peptide transport system, ATPase component

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787548, Length=330, Percent_Identity=84.5454545454545, Blast_Score=595, Evalue=1e-171,
Organism=Escherichia coli, GI1789963, Length=328, Percent_Identity=42.9878048780488, Blast_Score=275, Evalue=2e-75,
Organism=Escherichia coli, GI1787759, Length=328, Percent_Identity=37.8048780487805, Blast_Score=212, Evalue=3e-56,
Organism=Escherichia coli, GI48994883, Length=328, Percent_Identity=37.5, Blast_Score=206, Evalue=1e-54,
Organism=Escherichia coli, GI1787500, Length=329, Percent_Identity=34.3465045592705, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI145693107, Length=332, Percent_Identity=33.433734939759, Blast_Score=175, Evalue=4e-45,
Organism=Escherichia coli, GI1788506, Length=263, Percent_Identity=37.2623574144487, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI1787758, Length=313, Percent_Identity=32.5878594249201, Blast_Score=150, Evalue=8e-38,
Organism=Escherichia coli, GI1789962, Length=313, Percent_Identity=31.3099041533546, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI1789890, Length=261, Percent_Identity=31.0344827586207, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1787547, Length=275, Percent_Identity=29.8181818181818, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI48994997, Length=263, Percent_Identity=30.4182509505703, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1786398, Length=278, Percent_Identity=29.4964028776978, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1789891, Length=252, Percent_Identity=30.1587301587302, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1789032, Length=245, Percent_Identity=26.1224489795918, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI1789873, Length=223, Percent_Identity=30.4932735426009, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI87081791, Length=265, Percent_Identity=27.1698113207547, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI87081834, Length=226, Percent_Identity=30.5309734513274, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1788225, Length=261, Percent_Identity=27.2030651340996, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1787029, Length=251, Percent_Identity=24.3027888446215, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787712, Length=257, Percent_Identity=28.4046692607004, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788450, Length=251, Percent_Identity=25.8964143426295, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1787105, Length=239, Percent_Identity=27.1966527196653, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790162, Length=260, Percent_Identity=23.8461538461538, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786703, Length=241, Percent_Identity=27.3858921161826, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1789672, Length=243, Percent_Identity=27.5720164609054, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787089, Length=229, Percent_Identity=27.9475982532751, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1786872, Length=205, Percent_Identity=30.2439024390244, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790544, Length=230, Percent_Identity=27.3913043478261, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1789864, Length=272, Percent_Identity=25.7352941176471, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1789991, Length=239, Percent_Identity=28.8702928870293, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786253, Length=227, Percent_Identity=26.431718061674, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1786345, Length=224, Percent_Identity=25.4464285714286, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790467, Length=261, Percent_Identity=24.1379310344828, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87082267, Length=245, Percent_Identity=23.6734693877551, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI48995001, Length=225, Percent_Identity=27.5555555555556, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1787792, Length=249, Percent_Identity=28.1124497991968, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788644, Length=259, Percent_Identity=24.7104247104247, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1787370, Length=245, Percent_Identity=23.265306122449, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1787112, Length=256, Percent_Identity=24.21875, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1790190, Length=238, Percent_Identity=25.6302521008403, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787164, Length=215, Percent_Identity=26.5116279069767, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR003593
- InterPro:   IPR010066
- InterPro:   IPR013563 [H]

Pfam domain/function: PF00005 ABC_tran; PF08352 oligo_HPY [H]

EC number: NA

Molecular weight: Translated: 37465; Mature: 37334

Theoretical pI: Translated: 8.81; Mature: 8.81

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLLDIRNLTIEFMTAEGPVKAVDRVSMTLSEGEVRGLVGESGSGKSLIAKAICGVTKDN
CCCCCCCCCEEEEEECCCCHHHHHHHHHEECCCCEEEEECCCCCCHHHHHHHHHCCCCCC
WRVTADRFRFDDIDLLQLTPRERRKLVGHNVSMIFQEPQSCLDPSESIGRQLAQAIPGWT
CEEEHHHCCCCCCCEEECCCHHHHHHHCCCHHHEEECCHHHCCCHHHHHHHHHHHCCCCC
YKGRWWQRFNWRKRRAIELLHRVGIKDHKDIMGSFPYELTDGECQKVMIAIALANQPRLL
CCCCHHHHCCHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCHHHEEEEEEEECCCCEEE
IADEPTNAMEPTTQAQIFRLLARLNQNNNTTILLISHDLQMMSKWADRVNVLYCGQTVES
EEECCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHCEEEEECCCCCC
AQCEDLLAAPHHPYTQALIRSMPDFGRALPHKSRLNTLPGAIPSLEHLPIGCRLGPRCPY
HHHHHHHCCCCCHHHHHHHHCCCHHHHHCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCH
AQKKCIETPRLRPVKNHLFACHFPLNMEEQ
HHHHHCCCCCCCCHHHCEEEEECCCCCCCC
>Mature Secondary Structure 
PLLDIRNLTIEFMTAEGPVKAVDRVSMTLSEGEVRGLVGESGSGKSLIAKAICGVTKDN
CCCCCCCCEEEEEECCCCHHHHHHHHHEECCCCEEEEECCCCCCHHHHHHHHHCCCCCC
WRVTADRFRFDDIDLLQLTPRERRKLVGHNVSMIFQEPQSCLDPSESIGRQLAQAIPGWT
CEEEHHHCCCCCCCEEECCCHHHHHHHCCCHHHEEECCHHHCCCHHHHHHHHHHHCCCCC
YKGRWWQRFNWRKRRAIELLHRVGIKDHKDIMGSFPYELTDGECQKVMIAIALANQPRLL
CCCCHHHHCCHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCHHHEEEEEEEECCCCEEE
IADEPTNAMEPTTQAQIFRLLARLNQNNNTTILLISHDLQMMSKWADRVNVLYCGQTVES
EEECCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHCEEEEECCCCCC
AQCEDLLAAPHHPYTQALIRSMPDFGRALPHKSRLNTLPGAIPSLEHLPIGCRLGPRCPY
HHHHHHHCCCCCHHHHHHHHCCCHHHHHCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCH
AQKKCIETPRLRPVKNHLFACHFPLNMEEQ
HHHHHCCCCCCCCHHHCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; peptides [Periplasm]; H2O [C]

Specific reaction: ATP + peptides [Periplasm] + H2O = ADP + phosphate + peptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]