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The map label for this gene is pitA [H]

Identifier: 157370799

GI number: 157370799

Start: 2813756

End: 2815366

Strand: Direct

Name: pitA [H]

Synonym: Spro_2559

Alternate gene names: 157370799

Gene position: 2813756-2815366 (Clockwise)

Preceding gene: 157370797

Following gene: 157370800

Centisome position: 51.64

GC content: 56.86

Gene sequence:

>1611_bases
ATGAGCGATAACAGCGCCGTTCAGGCAGGTGCGCCAACCGCGTCCAGCCTGCCAAAAATCTACCAAAAGAACAGTCGACT
CACTGTTCTTTTTTTTGTTTTTTTATTAGTGCTGGGGATAGCTTTTGCCGGGGTGAATTTATTTAACGACGTTAGCGATG
CCGGTGCAGTATATACCAGCTACCTGCCGTTCCTTTTATTGGGGTTAGCGTTGCTGATTGCGCTGGGTTTTGAATTTGTT
AATGGTTTTCATGATACCGCCAATGCGGTGGCCACCGTTATTTATACCCATTCATTGTCGCCCATGGTGGCCGTGGTTTG
GTCAGGGTTCTTTAACTTTCTCGGCGTGTTGCTTTCCAGCGGAGTGGTGGCGTTCGGCATCATTTCGCTGTTGCCGGTTG
AGTTGATCTTGCAGGCCGGTACCGGCAATGGCTTTGCCATGGTTTACGCCCTGCTGTTCTCGGCGATTATCTGGAACCTC
GGCACCTGGTGGCTCGGGCTGCCGGCCTCCTCGTCTCATACCCTGATTGGCTCGATTATCGGCGTTGGGGTAGCCAATGC
GCTAATCCATGGCCGCACCGGCACCAGCGGTGTTGACTGGGGCCAGGCGATTAAGGTGGGCTACGCCTTGTTGCTTTCCC
CGGTGATCGGTTTTGTGTTTGCCGCCCTGCTGCTGCTGGCGCTGAAAGTCTTCGTCAAAAATCGTCAGTTGTACACCGCC
CCCAAGAATGATTCGCCGCCGCCGCTGTGGATCCGCGGTTTGCTGATCCTCACCTGTACCGGGGTTTCCTTTGCCCATGG
CTCCAACGACGGGCAAAAAGGCATGGGGCTGATCATGCTGATCCTGGTCGGGACCATGCCGATTGCCTACGCGCTGAACC
GCTCCATGCCGCCCGAGCAAATCCCCCGCGTGGCGGCACTGGCGGAGGTCACCAAAAACCAACTGCTGCACCAGTTCCCG
CAGGTCAGCCAGACTCCGCCGCGCGACGTGCTGACCGGCTATGTGCGTACCAGTGAACTGACCGCAGAAGTGGTCCCAGC
GCTGGCGCAGTTGACCGGGGCCATTGGCGATCAAATTCGTCAGTACGGCTCGGTCGACAAAATCCCTGCGCAGGCGGTTT
CCAACACCCGTAACGATATGTATCTGGCATCGGAGGTGATTAAACACCTTAAGTCGGAAAAACAGCTGCAATTATCCGCT
GACTCGCAGCGCAATCTGGATGCCCTGAAAAGCGATCTGGACAACGCCACCCGCTTTATCCCGTTCTGGGTCAAGGTGGT
GGTAGCTATTGCTCTGGGGTTGGGCACCATGGTCGGCTGGCGGCGCATTGTGGTCACCGTTGGTGAGAAAATCGGCAAAA
GTCATCTGACCTATGCCCAGGGGGCCAGTGCCGAACTGGTGGCGATGACCACTATCGGCGCGGCGGACATTTTTGGTTTA
CCGGTCTCCACCACCCACGTTCTGTCATCCGGCATCGCCGGTACCATGGCGGCCAACCGCTCCGGCCTGCAAATGTCCAC
CCTGCGCAATCTGCTGATGGCCTGGGTGTTGACGCTGCCGGCCTCGGTGCTGCTTTCTGCCGGGCTGTACTGGATTTTCA
CCCATTTCTAA

Upstream 100 bases:

>100_bases
TATTAGCGTCATAAAAAAGTCACATTATTTCCCAATACTTTGATGGCAGCACTGTACAACATCGTCAGTATTCTAATGAA
GTCTATCGGGAAGGTCCTTT

Downstream 100 bases:

>100_bases
AACCGGGCTAACACGGAGAATTAATTATGGCCATGCATGAATTTGACCGCGACGAAAGCTTCAACCAACGCCTGCTGCAG
GAGTTTTACGACAGTTACGA

Product: phosphate transporter

Products: Proton [Cytoplasm]; phosphate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 536; Mature: 535

Protein sequence:

>536_residues
MSDNSAVQAGAPTASSLPKIYQKNSRLTVLFFVFLLVLGIAFAGVNLFNDVSDAGAVYTSYLPFLLLGLALLIALGFEFV
NGFHDTANAVATVIYTHSLSPMVAVVWSGFFNFLGVLLSSGVVAFGIISLLPVELILQAGTGNGFAMVYALLFSAIIWNL
GTWWLGLPASSSHTLIGSIIGVGVANALIHGRTGTSGVDWGQAIKVGYALLLSPVIGFVFAALLLLALKVFVKNRQLYTA
PKNDSPPPLWIRGLLILTCTGVSFAHGSNDGQKGMGLIMLILVGTMPIAYALNRSMPPEQIPRVAALAEVTKNQLLHQFP
QVSQTPPRDVLTGYVRTSELTAEVVPALAQLTGAIGDQIRQYGSVDKIPAQAVSNTRNDMYLASEVIKHLKSEKQLQLSA
DSQRNLDALKSDLDNATRFIPFWVKVVVAIALGLGTMVGWRRIVVTVGEKIGKSHLTYAQGASAELVAMTTIGAADIFGL
PVSTTHVLSSGIAGTMAANRSGLQMSTLRNLLMAWVLTLPASVLLSAGLYWIFTHF

Sequences:

>Translated_536_residues
MSDNSAVQAGAPTASSLPKIYQKNSRLTVLFFVFLLVLGIAFAGVNLFNDVSDAGAVYTSYLPFLLLGLALLIALGFEFV
NGFHDTANAVATVIYTHSLSPMVAVVWSGFFNFLGVLLSSGVVAFGIISLLPVELILQAGTGNGFAMVYALLFSAIIWNL
GTWWLGLPASSSHTLIGSIIGVGVANALIHGRTGTSGVDWGQAIKVGYALLLSPVIGFVFAALLLLALKVFVKNRQLYTA
PKNDSPPPLWIRGLLILTCTGVSFAHGSNDGQKGMGLIMLILVGTMPIAYALNRSMPPEQIPRVAALAEVTKNQLLHQFP
QVSQTPPRDVLTGYVRTSELTAEVVPALAQLTGAIGDQIRQYGSVDKIPAQAVSNTRNDMYLASEVIKHLKSEKQLQLSA
DSQRNLDALKSDLDNATRFIPFWVKVVVAIALGLGTMVGWRRIVVTVGEKIGKSHLTYAQGASAELVAMTTIGAADIFGL
PVSTTHVLSSGIAGTMAANRSGLQMSTLRNLLMAWVLTLPASVLLSAGLYWIFTHF
>Mature_535_residues
SDNSAVQAGAPTASSLPKIYQKNSRLTVLFFVFLLVLGIAFAGVNLFNDVSDAGAVYTSYLPFLLLGLALLIALGFEFVN
GFHDTANAVATVIYTHSLSPMVAVVWSGFFNFLGVLLSSGVVAFGIISLLPVELILQAGTGNGFAMVYALLFSAIIWNLG
TWWLGLPASSSHTLIGSIIGVGVANALIHGRTGTSGVDWGQAIKVGYALLLSPVIGFVFAALLLLALKVFVKNRQLYTAP
KNDSPPPLWIRGLLILTCTGVSFAHGSNDGQKGMGLIMLILVGTMPIAYALNRSMPPEQIPRVAALAEVTKNQLLHQFPQ
VSQTPPRDVLTGYVRTSELTAEVVPALAQLTGAIGDQIRQYGSVDKIPAQAVSNTRNDMYLASEVIKHLKSEKQLQLSAD
SQRNLDALKSDLDNATRFIPFWVKVVVAIALGLGTMVGWRRIVVTVGEKIGKSHLTYAQGASAELVAMTTIGAADIFGLP
VSTTHVLSSGIAGTMAANRSGLQMSTLRNLLMAWVLTLPASVLLSAGLYWIFTHF

Specific function: Low-affinity inorganic phosphate transport. Can also transport arsenate [H]

COG id: COG0306

COG function: function code P; Phosphate/sulphate permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family. Pit subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789907, Length=485, Percent_Identity=43.7113402061856, Blast_Score=382, Evalue=1e-107,
Organism=Escherichia coli, GI1789360, Length=475, Percent_Identity=42.1052631578947, Blast_Score=365, Evalue=1e-102,
Organism=Caenorhabditis elegans, GI25146401, Length=511, Percent_Identity=24.6575342465753, Blast_Score=87, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001204 [H]

Pfam domain/function: PF01384 PHO4 [H]

EC number: NA

Molecular weight: Translated: 57083; Mature: 56951

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDNSAVQAGAPTASSLPKIYQKNSRLTVLFFVFLLVLGIAFAGVNLFNDVSDAGAVYTS
CCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YLPFLLLGLALLIALGFEFVNGFHDTANAVATVIYTHSLSPMVAVVWSGFFNFLGVLLSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHC
GVVAFGIISLLPVELILQAGTGNGFAMVYALLFSAIIWNLGTWWLGLPASSSHTLIGSII
CHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHEECCCCCCCHHHHHHH
GVGVANALIHGRTGTSGVDWGQAIKVGYALLLSPVIGFVFAALLLLALKVFVKNRQLYTA
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEC
PKNDSPPPLWIRGLLILTCTGVSFAHGSNDGQKGMGLIMLILVGTMPIAYALNRSMPPEQ
CCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHH
IPRVAALAEVTKNQLLHQFPQVSQTPPRDVLTGYVRTSELTAEVVPALAQLTGAIGDQIR
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QYGSVDKIPAQAVSNTRNDMYLASEVIKHLKSEKQLQLSADSQRNLDALKSDLDNATRFI
HHCCCCCCCHHHHHCCCCHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHH
PFWVKVVVAIALGLGTMVGWRRIVVTVGEKIGKSHLTYAQGASAELVAMTTIGAADIFGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCHHCCCCCCEEEEEECCHHHHCCC
PVSTTHVLSSGIAGTMAANRSGLQMSTLRNLLMAWVLTLPASVLLSAGLYWIFTHF
CCHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCC
>Mature Secondary Structure 
SDNSAVQAGAPTASSLPKIYQKNSRLTVLFFVFLLVLGIAFAGVNLFNDVSDAGAVYTS
CCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YLPFLLLGLALLIALGFEFVNGFHDTANAVATVIYTHSLSPMVAVVWSGFFNFLGVLLSS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHC
GVVAFGIISLLPVELILQAGTGNGFAMVYALLFSAIIWNLGTWWLGLPASSSHTLIGSII
CHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCHHHEECCCCCCCHHHHHHH
GVGVANALIHGRTGTSGVDWGQAIKVGYALLLSPVIGFVFAALLLLALKVFVKNRQLYTA
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEC
PKNDSPPPLWIRGLLILTCTGVSFAHGSNDGQKGMGLIMLILVGTMPIAYALNRSMPPEQ
CCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHH
IPRVAALAEVTKNQLLHQFPQVSQTPPRDVLTGYVRTSELTAEVVPALAQLTGAIGDQIR
HHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QYGSVDKIPAQAVSNTRNDMYLASEVIKHLKSEKQLQLSADSQRNLDALKSDLDNATRFI
HHCCCCCCCHHHHHCCCCHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHH
PFWVKVVVAIALGLGTMVGWRRIVVTVGEKIGKSHLTYAQGASAELVAMTTIGAADIFGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCHHCCCCCCEEEEEECCHHHHCCC
PVSTTHVLSSGIAGTMAANRSGLQMSTLRNLLMAWVLTLPASVLLSAGLYWIFTHF
CCHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; phosphate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + phosphate [Periplasm] = Proton [Cytoplasm] + phosphate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]