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The map label for this gene is yajO [H]

Identifier: 157370709

GI number: 157370709

Start: 2704599

End: 2705645

Strand: Direct

Name: yajO [H]

Synonym: Spro_2469

Alternate gene names: 157370709

Gene position: 2704599-2705645 (Clockwise)

Preceding gene: 157370708

Following gene: 157370710

Centisome position: 49.64

GC content: 55.3

Gene sequence:

>1047_bases
ATGGAATACATCAATCTTGGTAATTGTGGGCTGAAAGTTTCCCGTTTGTGTCTCGGTACCATGAATATGGGTAGCAAACA
GTGGAAACCCTGGATCTTCGACGAACACCAAAGTGAGCCGCTGATCCGCCATGCGCTGGAGTGTGGCATCAACTTTATTG
ATCTGGCGGATTTCTACTCCAGCGGTGCAGGCGAAGAAGTCGTAGGCAATATCATTGGGCGCTTGGCCCAGCGCGACGAA
CTGGTGCTGGCCACTAAAGTCGGTTACCCGATTGGTGGCGGCGCCAATAATCAGGGGCATTCACGCAAGCACATCATGGC
CAGCATTGACGCCAGCCTGCGCCGCCTGGGTACCGATTATGTCGATATTTACATGCTGCACTATTTCGATGTGAATACGC
CGATCGAAGAAACCTGGTCGGCGATGAACGATATCGTCCGCTCCGGCAAAGCCCGATATGTCGGCGTATCGACCATGTCT
GCCTGGCAGTTGGCCAAAATTCTGTGGATATGTGAGCGCCACGGCTTAGTCAAACCCATCAACATGCAGTTGCAACTCAA
CTGCGCCTACCGCGAAGAGGAACGGGAGATGATCCCTTTGTGTCGCGATCAGGGATTGGGCGTATCGGTATTCAGCCCAC
TGGCGCGCGGTTTATTAAGCTGCGATTTCAACTCGGTGCGTAACCAGACGGATTTCTTCACTCAGGAAATGTACGCCGAC
GCCACCTCACGCAACGTGGCCCAATCGGTCAGTCTGGTGGCGTCGCTACGGGGTATCCCTCCGGCACAGGTTGCCCAGGC
CTGGGTGCTCAGCCACCCGGGGGGCGACTGCATGCTGGTCGGGGCCGATACGGCGCAGCAAATAGACAGTGCCGTCAGTG
CCTTGTCTACCCCGCTCAGTGAGGATGAACGCTACGAACTGGAACGCCACTATACCCCATGCGATGTCATCAATGATTAC
ACCGCCGGTAAGCGTATAACGCGTGAGAGCCGCCCAGCCAACGGGCTATTTGCCATGGACAATACCGACACAAGGAACAT
TGCATGA

Upstream 100 bases:

>100_bases
CACGCTGCGATGAATCGCTTACCCAACCGCAGCCAGCTTGCCGACGCCCTGCCGCAATTGGCTAACCCCTTCTATACGCC
GCGTGCCTGAGGAAAACCCC

Downstream 100 bases:

>100_bases
CTGACTATTCTTCTTTACTGCGCAACGGTTGGTACTGTGACGGCCAATGGCGAACCAGTACCCAGCACTATCAGGTCAGC
AATCCCGCCACCGGAGAATC

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 348; Mature: 348

Protein sequence:

>348_residues
MEYINLGNCGLKVSRLCLGTMNMGSKQWKPWIFDEHQSEPLIRHALECGINFIDLADFYSSGAGEEVVGNIIGRLAQRDE
LVLATKVGYPIGGGANNQGHSRKHIMASIDASLRRLGTDYVDIYMLHYFDVNTPIEETWSAMNDIVRSGKARYVGVSTMS
AWQLAKILWICERHGLVKPINMQLQLNCAYREEEREMIPLCRDQGLGVSVFSPLARGLLSCDFNSVRNQTDFFTQEMYAD
ATSRNVAQSVSLVASLRGIPPAQVAQAWVLSHPGGDCMLVGADTAQQIDSAVSALSTPLSEDERYELERHYTPCDVINDY
TAGKRITRESRPANGLFAMDNTDTRNIA

Sequences:

>Translated_348_residues
MEYINLGNCGLKVSRLCLGTMNMGSKQWKPWIFDEHQSEPLIRHALECGINFIDLADFYSSGAGEEVVGNIIGRLAQRDE
LVLATKVGYPIGGGANNQGHSRKHIMASIDASLRRLGTDYVDIYMLHYFDVNTPIEETWSAMNDIVRSGKARYVGVSTMS
AWQLAKILWICERHGLVKPINMQLQLNCAYREEEREMIPLCRDQGLGVSVFSPLARGLLSCDFNSVRNQTDFFTQEMYAD
ATSRNVAQSVSLVASLRGIPPAQVAQAWVLSHPGGDCMLVGADTAQQIDSAVSALSTPLSEDERYELERHYTPCDVINDY
TAGKRITRESRPANGLFAMDNTDTRNIA
>Mature_348_residues
MEYINLGNCGLKVSRLCLGTMNMGSKQWKPWIFDEHQSEPLIRHALECGINFIDLADFYSSGAGEEVVGNIIGRLAQRDE
LVLATKVGYPIGGGANNQGHSRKHIMASIDASLRRLGTDYVDIYMLHYFDVNTPIEETWSAMNDIVRSGKARYVGVSTMS
AWQLAKILWICERHGLVKPINMQLQLNCAYREEEREMIPLCRDQGLGVSVFSPLARGLLSCDFNSVRNQTDFFTQEMYAD
ATSRNVAQSVSLVASLRGIPPAQVAQAWVLSHPGGDCMLVGADTAQQIDSAVSALSTPLSEDERYELERHYTPCDVINDY
TAGKRITRESRPANGLFAMDNTDTRNIA

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=308, Percent_Identity=33.7662337662338, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI4504825, Length=306, Percent_Identity=33.6601307189542, Blast_Score=135, Evalue=5e-32,
Organism=Homo sapiens, GI27436964, Length=307, Percent_Identity=31.5960912052117, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI27436962, Length=307, Percent_Identity=31.5960912052117, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI27436966, Length=307, Percent_Identity=31.2703583061889, Blast_Score=131, Evalue=8e-31,
Organism=Homo sapiens, GI27436971, Length=309, Percent_Identity=31.7152103559871, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI223718702, Length=208, Percent_Identity=31.25, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI41152114, Length=298, Percent_Identity=28.5234899328859, Blast_Score=95, Evalue=8e-20,
Organism=Homo sapiens, GI41327764, Length=208, Percent_Identity=32.2115384615385, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI223718708, Length=168, Percent_Identity=31.547619047619, Blast_Score=79, Evalue=6e-15,
Organism=Escherichia coli, GI87081735, Length=323, Percent_Identity=43.0340557275542, Blast_Score=253, Evalue=1e-68,
Organism=Escherichia coli, GI1789375, Length=327, Percent_Identity=32.4159021406728, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1789199, Length=342, Percent_Identity=27.7777777777778, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1788070, Length=320, Percent_Identity=31.25, Blast_Score=122, Evalue=5e-29,
Organism=Escherichia coli, GI1788081, Length=276, Percent_Identity=30.0724637681159, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1787674, Length=304, Percent_Identity=25.3289473684211, Blast_Score=71, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6325169, Length=337, Percent_Identity=32.3442136498516, Blast_Score=194, Evalue=2e-50,
Organism=Saccharomyces cerevisiae, GI6323998, Length=324, Percent_Identity=25.9259259259259, Blast_Score=108, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6319958, Length=296, Percent_Identity=27.7027027027027, Blast_Score=102, Evalue=8e-23,
Organism=Saccharomyces cerevisiae, GI6319951, Length=217, Percent_Identity=29.4930875576037, Blast_Score=92, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6322615, Length=254, Percent_Identity=27.9527559055118, Blast_Score=91, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6321052, Length=153, Percent_Identity=31.3725490196078, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6320079, Length=111, Percent_Identity=32.4324324324324, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24640980, Length=343, Percent_Identity=28.2798833819242, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI45549126, Length=343, Percent_Identity=28.2798833819242, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24646155, Length=310, Percent_Identity=28.3870967741935, Blast_Score=92, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24657054, Length=284, Percent_Identity=26.4084507042254, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24644950, Length=294, Percent_Identity=26.1904761904762, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24663317, Length=232, Percent_Identity=25.8620689655172, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24646159, Length=161, Percent_Identity=32.2981366459627, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI20129731, Length=227, Percent_Identity=25.9911894273128, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 38663; Mature: 38663

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEYINLGNCGLKVSRLCLGTMNMGSKQWKPWIFDEHQSEPLIRHALECGINFIDLADFYS
CCEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEEHHHHHC
SGAGEEVVGNIIGRLAQRDELVLATKVGYPIGGGANNQGHSRKHIMASIDASLRRLGTDY
CCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCH
VDIYMLHYFDVNTPIEETWSAMNDIVRSGKARYVGVSTMSAWQLAKILWICERHGLVKPI
HEEEEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHCCCCCCC
NMQLQLNCAYREEEREMIPLCRDQGLGVSVFSPLARGLLSCDFNSVRNQTDFFTQEMYAD
CEEEEEEEECCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHH
ATSRNVAQSVSLVASLRGIPPAQVAQAWVLSHPGGDCMLVGADTAQQIDSAVSALSTPLS
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHCCCC
EDERYELERHYTPCDVINDYTAGKRITRESRPANGLFAMDNTDTRNIA
CCHHHHHHHCCCCHHHHCCCCCCCHHHCCCCCCCCEEEECCCCCCCCC
>Mature Secondary Structure
MEYINLGNCGLKVSRLCLGTMNMGSKQWKPWIFDEHQSEPLIRHALECGINFIDLADFYS
CCEEECCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEEHHHHHC
SGAGEEVVGNIIGRLAQRDELVLATKVGYPIGGGANNQGHSRKHIMASIDASLRRLGTDY
CCCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCH
VDIYMLHYFDVNTPIEETWSAMNDIVRSGKARYVGVSTMSAWQLAKILWICERHGLVKPI
HEEEEEEEECCCCCHHHHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHCCCCCCC
NMQLQLNCAYREEEREMIPLCRDQGLGVSVFSPLARGLLSCDFNSVRNQTDFFTQEMYAD
CEEEEEEEECCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHH
ATSRNVAQSVSLVASLRGIPPAQVAQAWVLSHPGGDCMLVGADTAQQIDSAVSALSTPLS
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHCCCC
EDERYELERHYTPCDVINDYTAGKRITRESRPANGLFAMDNTDTRNIA
CCHHHHHHHCCCCHHHHCCCCCCCHHHCCCCCCCCEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]