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The map label for this gene is metI [H]

Identifier: 157369639

GI number: 157369639

Start: 1522774

End: 1523442

Strand: Reverse

Name: metI [H]

Synonym: Spro_1396

Alternate gene names: 157369639

Gene position: 1523442-1522774 (Counterclockwise)

Preceding gene: 157369640

Following gene: 157369638

Centisome position: 27.96

GC content: 57.55

Gene sequence:

>669_bases
ATGATTGAGTCATGGTTCCCTCATTTGCGTATTGACCAGTTGCTGAACGCCACCTGGGAAACCCTGTACATGACCGGCAT
CGCCGGGTTGGCTACGCTGGTGCTTGGCATCGTACTGGGCGTACTGCTGTTTCTGACCTCTCGCGGCCAACTGTTGCAAA
ACCGCGCCGTCTATTCGCTGATTTCAGTGCTGGTCAACGTATTCCGCTCCATCCCCTTCATCATTCTGATCGTGCTGCTG
ATCCCGTTCACCAAGACGCTGATCGGCACCATTTTGGGGGCCGATGCCGCGCTGCCGGCGCTGATTGTCGGCGCCGCGCC
CTTCTACGCCCGGCTGGTTGAAATTGGCCTGCGCGAGGTGGACAAGGGAGTCATAGAGGCGGCACGTTCCATGGGAGCCA
AAACCAGCACCATTATTTTCCGCGTGCTGCTGCCGGAGTCTTCCCCGGCGCTGGTTTCCGGAATTACCGTCACCCTGATA
GCACTGGTGAGCTACACCGCCATGGCCGGAGTGATCGGCGCTGGCGGGCTGGGCAATCTGGCCTATCTGGAAGGTTTTCA
ACGCAATCACGGTGACGTGACGCTGGTAGCGACGCTGACGATCCTGCTGATCGTTTTCGTTATCCAGTTCATCGGCGACA
CCATTACAACAACGCTCGATAAACGATAA

Upstream 100 bases:

>100_bases
TTTGGCGAGCTGTATATCCACGTCGAAGGCAACGACCTGCAAATCGACAGCATGCTGAAATTATTGAGAGAACAACAAAT
CGCCGTTGAGGTGATTAAAC

Downstream 100 bases:

>100_bases
ATAACCAGGGAATAATGATGATGAAAAAGCAAATAATGATGCTGGCTTTCGCCTCACTGACCGCGTTGAGCTCCTTTGGC
GCCGCCGCGGAAACCAGGCT

Product: binding-protein-dependent transport systems inner membrane component

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MIESWFPHLRIDQLLNATWETLYMTGIAGLATLVLGIVLGVLLFLTSRGQLLQNRAVYSLISVLVNVFRSIPFIILIVLL
IPFTKTLIGTILGADAALPALIVGAAPFYARLVEIGLREVDKGVIEAARSMGAKTSTIIFRVLLPESSPALVSGITVTLI
ALVSYTAMAGVIGAGGLGNLAYLEGFQRNHGDVTLVATLTILLIVFVIQFIGDTITTTLDKR

Sequences:

>Translated_222_residues
MIESWFPHLRIDQLLNATWETLYMTGIAGLATLVLGIVLGVLLFLTSRGQLLQNRAVYSLISVLVNVFRSIPFIILIVLL
IPFTKTLIGTILGADAALPALIVGAAPFYARLVEIGLREVDKGVIEAARSMGAKTSTIIFRVLLPESSPALVSGITVTLI
ALVSYTAMAGVIGAGGLGNLAYLEGFQRNHGDVTLVATLTILLIVFVIQFIGDTITTTLDKR
>Mature_222_residues
MIESWFPHLRIDQLLNATWETLYMTGIAGLATLVLGIVLGVLLFLTSRGQLLQNRAVYSLISVLVNVFRSIPFIILIVLL
IPFTKTLIGTILGADAALPALIVGAAPFYARLVEIGLREVDKGVIEAARSMGAKTSTIIFRVLLPESSPALVSGITVTLI
ALVSYTAMAGVIGAGGLGNLAYLEGFQRNHGDVTLVATLTILLIVFVIQFIGDTITTTLDKR

Specific function: Part of the ABC transporter complex metNIQ involved in methionine import. Responsible for the translocation of the substrate across the membrane (Probable). It has also been shown to be involved in methionine sulfoxide transport [H]

COG id: COG2011

COG function: function code P; ABC-type metal ion transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1786397, Length=209, Percent_Identity=46.4114832535885, Blast_Score=157, Evalue=4e-40,
Organism=Escherichia coli, GI1788451, Length=203, Percent_Identity=27.0935960591133, Blast_Score=61, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 23749; Mature: 23749

Theoretical pI: Translated: 8.90; Mature: 8.90

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIESWFPHLRIDQLLNATWETLYMTGIAGLATLVLGIVLGVLLFLTSRGQLLQNRAVYSL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
ISVLVNVFRSIPFIILIVLLIPFTKTLIGTILGADAALPALIVGAAPFYARLVEIGLREV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DKGVIEAARSMGAKTSTIIFRVLLPESSPALVSGITVTLIALVSYTAMAGVIGAGGLGNL
HHHHHHHHHHCCCCHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
AYLEGFQRNHGDVTLVATLTILLIVFVIQFIGDTITTTLDKR
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIESWFPHLRIDQLLNATWETLYMTGIAGLATLVLGIVLGVLLFLTSRGQLLQNRAVYSL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
ISVLVNVFRSIPFIILIVLLIPFTKTLIGTILGADAALPALIVGAAPFYARLVEIGLREV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DKGVIEAARSMGAKTSTIIFRVLLPESSPALVSGITVTLIALVSYTAMAGVIGAGGLGNL
HHHHHHHHHHCCCCHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
AYLEGFQRNHGDVTLVATLTILLIVFVIQFIGDTITTTLDKR
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]