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The map label for this gene is xylB [H]

Identifier: 157369413

GI number: 157369413

Start: 1287524

End: 1288618

Strand: Direct

Name: xylB [H]

Synonym: Spro_1170

Alternate gene names: 157369413

Gene position: 1287524-1288618 (Clockwise)

Preceding gene: 157369412

Following gene: 157369414

Centisome position: 23.63

GC content: 44.57

Gene sequence:

>1095_bases
ATGATAAAAGCTATAGCTGCTGTGACCGAATCTGCTGATACACCTTTTACTGTTTGCGATATTGAACTTGAAGATCCACA
GGATTATGAAGTTTTGGTTCGCATCAAAGGTGTAGGTATCTGCCATACTGATTTGAGCTTCAAGCAAATAGGTCACTATG
CTCCAGGAGTTCTTGGGCATGAAGGTGCGGGAGTGGTTGAAAAAGTGGGAGCTGCCGTAACCCGCCTGGTTCCCGGTGAC
CATGTTGTTCTTAGTTACTTTGCTTGCCACCATTGTGAGACTTGCTTGGATGGACATCCTGCATACTGCGATAATATGGA
GGCTGCCAATATAAGTGGGGGGCGTGTAGATGGATCTACTCCTATTCAAATCAACGGTAAGCCTGGCAAAGGTTCTTTCT
TTTATCAATCCTCTTTCGCAAACTATGCCATTTCCCACGAGAACAATACGGTGAAGATAGACAAGACTCTACCGGTTGCT
TTGATGGGGCCATTGGGCTGTGGTTTGCAAACGGGGGCCGGTGCCGTTATTAATGCTCTTAAAGTTGGGGAAAACCAGGG
TATCGCTATTTTTGGTTTAGGCGCGGTTGGTCTTGCTGCAGTGATGGCTTCCAAGATTTCTGGTGCTAATCCTATTATTG
TTGTCGATATCGTCCCGGAGAAACTCGAACTAGCAAAACAACTTGGAGCAACTCATATTATAAATGGTGCAACAAGTGAT
GCGGTTAGCGAAATAAAACGTATCTCCGAGGGGGGAGTCGCATTTTCTCTTGAATGTGTTGGCGTTCCGAAACTCCTTGA
ACAAGCCGTAGAATCCCTGCGTCCTACCGGCGTGTGTGGTTTACTTGGTATGAGCAGCACTGAAGCTACGGCATCAATAA
AATTATTAGATTTACTGGGTGGTCGTACCGTCAAAGGGATTATAGAAGGAGATGCCGATCCTCAGGAATTTATTCCTAAA
TTGATTGAGTTCTATCGCTCGGGGCAATTTCCCTTTGATAAACTGCTCAAAACTTACCCGTTAGAAGATATAAATCTTGC
CATTGATGATATGAAAAATGGCTTGGTCGTTAAGCCAGTATTAATACCATCTTGA

Upstream 100 bases:

>100_bases
TATTTATTTGAATGAAATTGAGTTGATTTATTTTTTTAGTGTGAAGTAGAGTCTGGAAAACAATGGTAAGTGTAGGGTAA
ATATATCAGAGGAAATTGAA

Downstream 100 bases:

>100_bases
TGTTTTATTTTTAATAAAAATAAGGAGCCTGCCATGAATTTTCAAGAGGCGATCAATACCGGTAAGGTTACGCAAGAACA
GGCATTCCAGATATTTGACA

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: Benzyl alcohol dehydrogenase; BADH [H]

Number of amino acids: Translated: 364; Mature: 364

Protein sequence:

>364_residues
MIKAIAAVTESADTPFTVCDIELEDPQDYEVLVRIKGVGICHTDLSFKQIGHYAPGVLGHEGAGVVEKVGAAVTRLVPGD
HVVLSYFACHHCETCLDGHPAYCDNMEAANISGGRVDGSTPIQINGKPGKGSFFYQSSFANYAISHENNTVKIDKTLPVA
LMGPLGCGLQTGAGAVINALKVGENQGIAIFGLGAVGLAAVMASKISGANPIIVVDIVPEKLELAKQLGATHIINGATSD
AVSEIKRISEGGVAFSLECVGVPKLLEQAVESLRPTGVCGLLGMSSTEATASIKLLDLLGGRTVKGIIEGDADPQEFIPK
LIEFYRSGQFPFDKLLKTYPLEDINLAIDDMKNGLVVKPVLIPS

Sequences:

>Translated_364_residues
MIKAIAAVTESADTPFTVCDIELEDPQDYEVLVRIKGVGICHTDLSFKQIGHYAPGVLGHEGAGVVEKVGAAVTRLVPGD
HVVLSYFACHHCETCLDGHPAYCDNMEAANISGGRVDGSTPIQINGKPGKGSFFYQSSFANYAISHENNTVKIDKTLPVA
LMGPLGCGLQTGAGAVINALKVGENQGIAIFGLGAVGLAAVMASKISGANPIIVVDIVPEKLELAKQLGATHIINGATSD
AVSEIKRISEGGVAFSLECVGVPKLLEQAVESLRPTGVCGLLGMSSTEATASIKLLDLLGGRTVKGIIEGDADPQEFIPK
LIEFYRSGQFPFDKLLKTYPLEDINLAIDDMKNGLVVKPVLIPS
>Mature_364_residues
MIKAIAAVTESADTPFTVCDIELEDPQDYEVLVRIKGVGICHTDLSFKQIGHYAPGVLGHEGAGVVEKVGAAVTRLVPGD
HVVLSYFACHHCETCLDGHPAYCDNMEAANISGGRVDGSTPIQINGKPGKGSFFYQSSFANYAISHENNTVKIDKTLPVA
LMGPLGCGLQTGAGAVINALKVGENQGIAIFGLGAVGLAAVMASKISGANPIIVVDIVPEKLELAKQLGATHIINGATSD
AVSEIKRISEGGVAFSLECVGVPKLLEQAVESLRPTGVCGLLGMSSTEATASIKLLDLLGGRTVKGIIEGDADPQEFIPK
LIEFYRSGQFPFDKLLKTYPLEDINLAIDDMKNGLVVKPVLIPS

Specific function: Oxidizes primary alcohols with an aromatic or cyclohex- 1-ene ring. It is highly specific for benzyl alcohol [H]

COG id: COG1062

COG function: function code C; Zn-dependent alcohol dehydrogenases, class III

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI34577061, Length=368, Percent_Identity=36.4130434782609, Blast_Score=206, Evalue=3e-53,
Organism=Homo sapiens, GI4501929, Length=369, Percent_Identity=34.4173441734417, Blast_Score=195, Evalue=6e-50,
Organism=Homo sapiens, GI4501933, Length=368, Percent_Identity=34.5108695652174, Blast_Score=192, Evalue=5e-49,
Organism=Homo sapiens, GI71565152, Length=374, Percent_Identity=34.7593582887701, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI71565154, Length=369, Percent_Identity=34.1463414634146, Blast_Score=182, Evalue=4e-46,
Organism=Homo sapiens, GI156523966, Length=372, Percent_Identity=31.4516129032258, Blast_Score=180, Evalue=2e-45,
Organism=Homo sapiens, GI4501939, Length=364, Percent_Identity=31.8681318681319, Blast_Score=176, Evalue=2e-44,
Organism=Homo sapiens, GI71743840, Length=371, Percent_Identity=30.188679245283, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI262073058, Length=371, Percent_Identity=30.188679245283, Blast_Score=159, Evalue=3e-39,
Organism=Homo sapiens, GI156627571, Length=366, Percent_Identity=27.3224043715847, Blast_Score=84, Evalue=3e-16,
Organism=Escherichia coli, GI1786552, Length=372, Percent_Identity=34.1397849462366, Blast_Score=161, Evalue=6e-41,
Organism=Escherichia coli, GI1788073, Length=345, Percent_Identity=27.2463768115942, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788407, Length=266, Percent_Identity=31.203007518797, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI87081918, Length=337, Percent_Identity=29.3768545994065, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI87082125, Length=278, Percent_Identity=25.8992805755396, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1790045, Length=373, Percent_Identity=22.2520107238606, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1786518, Length=355, Percent_Identity=27.0422535211268, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1787863, Length=281, Percent_Identity=28.1138790035587, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1788075, Length=291, Percent_Identity=26.4604810996564, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1790718, Length=340, Percent_Identity=26.4705882352941, Blast_Score=72, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI25146526, Length=375, Percent_Identity=34.4, Blast_Score=201, Evalue=5e-52,
Organism=Caenorhabditis elegans, GI71997431, Length=377, Percent_Identity=33.9522546419098, Blast_Score=196, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI17565904, Length=328, Percent_Identity=33.8414634146341, Blast_Score=177, Evalue=8e-45,
Organism=Caenorhabditis elegans, GI17562878, Length=363, Percent_Identity=26.9972451790634, Blast_Score=91, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17562584, Length=367, Percent_Identity=26.158038147139, Blast_Score=86, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17562582, Length=330, Percent_Identity=27.8787878787879, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71988145, Length=363, Percent_Identity=23.6914600550964, Blast_Score=72, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6320033, Length=375, Percent_Identity=32.2666666666667, Blast_Score=184, Evalue=1e-47,
Organism=Saccharomyces cerevisiae, GI6323729, Length=323, Percent_Identity=28.7925696594427, Blast_Score=85, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6323099, Length=290, Percent_Identity=27.2413793103448, Blast_Score=85, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6319621, Length=294, Percent_Identity=26.8707482993197, Blast_Score=66, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6323961, Length=274, Percent_Identity=27.7372262773723, Blast_Score=64, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6324486, Length=277, Percent_Identity=27.4368231046931, Blast_Score=63, Evalue=6e-11,
Organism=Drosophila melanogaster, GI17737895, Length=371, Percent_Identity=32.8840970350404, Blast_Score=186, Evalue=3e-47,
Organism=Drosophila melanogaster, GI17737897, Length=272, Percent_Identity=29.0441176470588, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI17137530, Length=259, Percent_Identity=29.3436293436293, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.90 [H]

Molecular weight: Translated: 38164; Mature: 38164

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKAIAAVTESADTPFTVCDIELEDPQDYEVLVRIKGVGICHTDLSFKQIGHYAPGVLGH
CCCHHHHHHCCCCCCEEEEEEEECCCCCEEEEEEEECCEEEECCCCHHHHHCCCCCCCCC
EGAGVVEKVGAAVTRLVPGDHVVLSYFACHHCETCLDGHPAYCDNMEAANISGGRVDGST
CCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
PIQINGKPGKGSFFYQSSFANYAISHENNTVKIDKTLPVALMGPLGCGLQTGAGAVINAL
CEEEECCCCCCCEEEECCCCCEEEECCCCEEEEECCCCEEEECCCCCCCCCCCHHHHHHH
KVGENQGIAIFGLGAVGLAAVMASKISGANPIIVVDIVPEKLELAKQLGATHIINGATSD
EECCCCCEEEEECHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHCCCCEEECCCCHH
AVSEIKRISEGGVAFSLECVGVPKLLEQAVESLRPTGVCGLLGMSSTEATASIKLLDLLG
HHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHCCCCCEEEEECCCCCCCHHEEEEEEHHC
GRTVKGIIEGDADPQEFIPKLIEFYRSGQFPFDKLLKTYPLEDINLAIDDMKNGLVVKPV
CCEEEEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCEEEEECCCCCEEEEEE
LIPS
ECCC
>Mature Secondary Structure
MIKAIAAVTESADTPFTVCDIELEDPQDYEVLVRIKGVGICHTDLSFKQIGHYAPGVLGH
CCCHHHHHHCCCCCCEEEEEEEECCCCCEEEEEEEECCEEEECCCCHHHHHCCCCCCCCC
EGAGVVEKVGAAVTRLVPGDHVVLSYFACHHCETCLDGHPAYCDNMEAANISGGRVDGST
CCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
PIQINGKPGKGSFFYQSSFANYAISHENNTVKIDKTLPVALMGPLGCGLQTGAGAVINAL
CEEEECCCCCCCEEEECCCCCEEEECCCCEEEEECCCCEEEECCCCCCCCCCCHHHHHHH
KVGENQGIAIFGLGAVGLAAVMASKISGANPIIVVDIVPEKLELAKQLGATHIINGATSD
EECCCCCEEEEECHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHCCCCEEECCCCHH
AVSEIKRISEGGVAFSLECVGVPKLLEQAVESLRPTGVCGLLGMSSTEATASIKLLDLLG
HHHHHHHHHCCCEEEEEEECCCHHHHHHHHHHCCCCCEEEEECCCCCCCHHEEEEEEHHC
GRTVKGIIEGDADPQEFIPKLIEFYRSGQFPFDKLLKTYPLEDINLAIDDMKNGLVVKPV
CCEEEEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCEEEEECCCCCEEEEEE
LIPS
ECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8496150; 1989592 [H]