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The map label for this gene is galE [H]

Identifier: 157369404

GI number: 157369404

Start: 1278730

End: 1279746

Strand: Direct

Name: galE [H]

Synonym: Spro_1161

Alternate gene names: 157369404

Gene position: 1278730-1279746 (Clockwise)

Preceding gene: 157369403

Following gene: 157369409

Centisome position: 23.47

GC content: 57.92

Gene sequence:

>1017_bases
ATGTCTATTCTGGTGACCGGCGGCGCCGGCTACATTGGTTCACATACGGTGTTGGCTTTGCTGGAACGTGGTGAAGATGT
GGTGGTGCTGGATAATTTGATCAACGCGTCCGAAGAGTCTTTGCGCCGCGTGGAGCAACTGACGGGCAGGGCCGCGACGT
TTTATCGGGGAGATGTACAGGATGCCGGCTGCCTGAAGCGTATCTTTGAGGAAAACAACGTTGCCTCAGTGATCCACTTT
GCCGGCCTGAAGGCGGTGGGGGAGTCCACCCAAAAACCGCTGGAGTACTATCAGAATAACGTGGCCGGTACCTTGGTGTT
GCTGGAGGCGATGCGCGAGGCGGGAGTCCATCAGTTCATCTTCAGCTCTTCCGCCACGGTGTACGGCGAACATGCGCCGG
TACCTTACCGGGAAGATATGCCGATTGGCGGCACTACCAGCCCTTACGGCACCTCCAAATGGATGGTGGAGCAGGTCCTG
CAGGACTTTGCCAGGGCTGAACCGGCATTTTCGATTATCGCGCTGCGCTACTTCAACCCGGTAGGCGCACATGAGTCGGG
CCTGATTGGCGAAGACCCGAGTGGGATCCCCAATAATCTGCTGCCTTATATCGCGCAGGTGGCCATCGGTCAGCGGGAAA
CTCTGAGCGTGTTTGGCGGCGACTATCCAACCAAGGACGGCACGGGCGTGCGCGACTACATTCACGTGATGGATGTGGCG
CAAGGCCATCTGGCGGCGATGGATCATTTAGCGCAGATTGCCGGGTTTAAAGCCTATAACCTGGGCTCCGGGGTCGGTTA
CTCGGTGCTGGAAATGGTGCGGGCGTTTGAAAAAGCCTCGGGCGTGACTATTCCTTATCAGATTTTACCGCGCCGTGCGG
GCGACCTGCCTGCCTTCTGGGCCGATGCCGGGTTGGCAAAACAGGAACTGGGCTGGCAAGTGCAGCGCGGGCTTGACGTG
ATGATGCGTGATACCTGGAACTGGCAAAGCAAAAATCCGCAGGGCTATCGCCGTTAA

Upstream 100 bases:

>100_bases
AACCGTTACGTAACATTGGTTCACGCTGAGCGGTAAGCCAGGCACGCGAGGCCCGCTGATACGGCGGGTTTTCGCTCCTG
ACACTGATTAAGGGGAAATT

Downstream 100 bases:

>100_bases
CAAACCTGCATAAAGGCTAAACCGGTAGGGGGCGAACATGCTCGTCCCGACTTAACCCGTTGATTATATGATAGGGCGCG
GCATGCAGCGCCCCTACCAT

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 338; Mature: 337

Protein sequence:

>338_residues
MSILVTGGAGYIGSHTVLALLERGEDVVVLDNLINASEESLRRVEQLTGRAATFYRGDVQDAGCLKRIFEENNVASVIHF
AGLKAVGESTQKPLEYYQNNVAGTLVLLEAMREAGVHQFIFSSSATVYGEHAPVPYREDMPIGGTTSPYGTSKWMVEQVL
QDFARAEPAFSIIALRYFNPVGAHESGLIGEDPSGIPNNLLPYIAQVAIGQRETLSVFGGDYPTKDGTGVRDYIHVMDVA
QGHLAAMDHLAQIAGFKAYNLGSGVGYSVLEMVRAFEKASGVTIPYQILPRRAGDLPAFWADAGLAKQELGWQVQRGLDV
MMRDTWNWQSKNPQGYRR

Sequences:

>Translated_338_residues
MSILVTGGAGYIGSHTVLALLERGEDVVVLDNLINASEESLRRVEQLTGRAATFYRGDVQDAGCLKRIFEENNVASVIHF
AGLKAVGESTQKPLEYYQNNVAGTLVLLEAMREAGVHQFIFSSSATVYGEHAPVPYREDMPIGGTTSPYGTSKWMVEQVL
QDFARAEPAFSIIALRYFNPVGAHESGLIGEDPSGIPNNLLPYIAQVAIGQRETLSVFGGDYPTKDGTGVRDYIHVMDVA
QGHLAAMDHLAQIAGFKAYNLGSGVGYSVLEMVRAFEKASGVTIPYQILPRRAGDLPAFWADAGLAKQELGWQVQRGLDV
MMRDTWNWQSKNPQGYRR
>Mature_337_residues
SILVTGGAGYIGSHTVLALLERGEDVVVLDNLINASEESLRRVEQLTGRAATFYRGDVQDAGCLKRIFEENNVASVIHFA
GLKAVGESTQKPLEYYQNNVAGTLVLLEAMREAGVHQFIFSSSATVYGEHAPVPYREDMPIGGTTSPYGTSKWMVEQVLQ
DFARAEPAFSIIALRYFNPVGAHESGLIGEDPSGIPNNLLPYIAQVAIGQRETLSVFGGDYPTKDGTGVRDYIHVMDVAQ
GHLAAMDHLAQIAGFKAYNLGSGVGYSVLEMVRAFEKASGVTIPYQILPRRAGDLPAFWADAGLAKQELGWQVQRGLDVM
MRDTWNWQSKNPQGYRR

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=341, Percent_Identity=56.891495601173, Blast_Score=407, Evalue=1e-114,
Organism=Homo sapiens, GI56118217, Length=341, Percent_Identity=56.891495601173, Blast_Score=407, Evalue=1e-114,
Organism=Homo sapiens, GI189083684, Length=341, Percent_Identity=56.891495601173, Blast_Score=407, Evalue=1e-114,
Organism=Homo sapiens, GI7657641, Length=275, Percent_Identity=28, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI42516563, Length=342, Percent_Identity=24.5614035087719, Blast_Score=72, Evalue=9e-13,
Organism=Escherichia coli, GI1786974, Length=336, Percent_Identity=60.4166666666667, Blast_Score=435, Evalue=1e-123,
Organism=Escherichia coli, GI48994969, Length=362, Percent_Identity=27.6243093922652, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1788353, Length=365, Percent_Identity=26.8493150684932, Blast_Score=86, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71982035, Length=345, Percent_Identity=51.8840579710145, Blast_Score=367, Evalue=1e-102,
Organism=Caenorhabditis elegans, GI71982038, Length=347, Percent_Identity=51.2968299711816, Blast_Score=365, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI17568069, Length=330, Percent_Identity=23.6363636363636, Blast_Score=78, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6319493, Length=344, Percent_Identity=51.7441860465116, Blast_Score=358, Evalue=1e-100,
Organism=Drosophila melanogaster, GI19923002, Length=343, Percent_Identity=55.9766763848396, Blast_Score=417, Evalue=1e-117,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36944; Mature: 36813

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILVTGGAGYIGSHTVLALLERGEDVVVLDNLINASEESLRRVEQLTGRAATFYRGDVQ
CEEEEECCCCCCHHHHHHHHHHCCCCEEEEHHHHCCCHHHHHHHHHHHCCHHEEECCCCC
DAGCLKRIFEENNVASVIHFAGLKAVGESTQKPLEYYQNNVAGTLVLLEAMREAGVHQFI
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHH
FSSSATVYGEHAPVPYREDMPIGGTTSPYGTSKWMVEQVLQDFARAEPAFSIIALRYFNP
HCCCCEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEHHHCCC
VGAHESGLIGEDPSGIPNNLLPYIAQVAIGQRETLSVFGGDYPTKDGTGVRDYIHVMDVA
CCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEHEECCCCCCCCCCCHHHHHHHHHHH
QGHLAAMDHLAQIAGFKAYNLGSGVGYSVLEMVRAFEKASGVTIPYQILPRRAGDLPAFW
HHHHHHHHHHHHHHCCCEECCCCCCCHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCHH
ADAGLAKQELGWQVQRGLDVMMRDTWNWQSKNPQGYRR
HCCCCHHHHHCHHHHHCCCEEHHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SILVTGGAGYIGSHTVLALLERGEDVVVLDNLINASEESLRRVEQLTGRAATFYRGDVQ
EEEEECCCCCCHHHHHHHHHHCCCCEEEEHHHHCCCHHHHHHHHHHHCCHHEEECCCCC
DAGCLKRIFEENNVASVIHFAGLKAVGESTQKPLEYYQNNVAGTLVLLEAMREAGVHQFI
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHH
FSSSATVYGEHAPVPYREDMPIGGTTSPYGTSKWMVEQVLQDFARAEPAFSIIALRYFNP
HCCCCEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEHHHCCC
VGAHESGLIGEDPSGIPNNLLPYIAQVAIGQRETLSVFGGDYPTKDGTGVRDYIHVMDVA
CCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCEEHEECCCCCCCCCCCHHHHHHHHHHH
QGHLAAMDHLAQIAGFKAYNLGSGVGYSVLEMVRAFEKASGVTIPYQILPRRAGDLPAFW
HHHHHHHHHHHHHHCCCEECCCCCCCHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCHH
ADAGLAKQELGWQVQRGLDVMMRDTWNWQSKNPQGYRR
HCCCCHHHHHCHHHHHCCCEEHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7507102 [H]