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The map label for this gene is phoB [H]

Identifier: 157369284

GI number: 157369284

Start: 1144656

End: 1145345

Strand: Direct

Name: phoB [H]

Synonym: Spro_1041

Alternate gene names: 157369284

Gene position: 1144656-1145345 (Clockwise)

Preceding gene: 157369281

Following gene: 157369285

Centisome position: 21.01

GC content: 54.35

Gene sequence:

>690_bases
ATGGCAAGACGCATACTGGTGGTGGAAGACGAAGCGCCGATCCGTGAGATGGTGTGCTTTGTGTTGGAACAGAATGGTTA
CCAACCGTTGGAAGCTGAGGATTATGACAGCGCAGTGACGCGCCTGTCTGAGCCGTTCCCTGATTTAGTGTTGCTCGACT
GGATGTTACCCGGAGGTTCCGGCATTCAGTTTATTAAACATATGAAGCGTGAAGCGATGACCCGCGATATTCCGGTGATG
ATGCTGACCGCACGCGGTGAAGAAGAAGACCGTGTCCGTGGGCTGGAGGTCGGGGCGGATGATTACATCACCAAACCCTT
CTCGCCGAAGGAGCTGGTGGCGCGCATCAAGGCGGTAATGCGCCGCATTTCACCGATGGCGGTGGAAGAAGTGATTGAAA
TGCAAGGGCTGAGCCTGGATCCTTCTTCACACCGGGTGATGGCCAACGAGCAGGCGCTGGATATGGGGCCGACCGAGTTC
AAATTGCTGCACTTCTTTATGACTCATCCAGAGCGTGTTTATAGCCGCGAACAGTTGCTTAATCACGTCTGGGGCACTAA
CGTTTATGTGGAAGACCGCACCGTTGACGTGCATATCCGTCGGCTCCGTAAGGCGTTAGAGACCAGTGGTCATGACAAAA
TGGTTCAAACCGTTCGGGGCACCGGCTACCGATTCTCAACGCGCTACTGA

Upstream 100 bases:

>100_bases
GTTTATTTCATGGCTATTTATTTCATAAATCTGTCACAAAACTGACGCATAATGGCGCCCGCAATCAACTGTGATCGCTA
ACACATTGGCAGGATTGACG

Downstream 100 bases:

>100_bases
TCGCGACGCGCTGGAGAATATGCCGTGCTAGAACGTCTATCCTGGAAGAGGCTGGCCCTGGAGCTGGCCCTTTTCTGCTT
GCCTGCCTTGTTGCTGGGGC

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 228

Protein sequence:

>229_residues
MARRILVVEDEAPIREMVCFVLEQNGYQPLEAEDYDSAVTRLSEPFPDLVLLDWMLPGGSGIQFIKHMKREAMTRDIPVM
MLTARGEEEDRVRGLEVGADDYITKPFSPKELVARIKAVMRRISPMAVEEVIEMQGLSLDPSSHRVMANEQALDMGPTEF
KLLHFFMTHPERVYSREQLLNHVWGTNVYVEDRTVDVHIRRLRKALETSGHDKMVQTVRGTGYRFSTRY

Sequences:

>Translated_229_residues
MARRILVVEDEAPIREMVCFVLEQNGYQPLEAEDYDSAVTRLSEPFPDLVLLDWMLPGGSGIQFIKHMKREAMTRDIPVM
MLTARGEEEDRVRGLEVGADDYITKPFSPKELVARIKAVMRRISPMAVEEVIEMQGLSLDPSSHRVMANEQALDMGPTEF
KLLHFFMTHPERVYSREQLLNHVWGTNVYVEDRTVDVHIRRLRKALETSGHDKMVQTVRGTGYRFSTRY
>Mature_228_residues
ARRILVVEDEAPIREMVCFVLEQNGYQPLEAEDYDSAVTRLSEPFPDLVLLDWMLPGGSGIQFIKHMKREAMTRDIPVMM
LTARGEEEDRVRGLEVGADDYITKPFSPKELVARIKAVMRRISPMAVEEVIEMQGLSLDPSSHRVMANEQALDMGPTEFK
LLHFFMTHPERVYSREQLLNHVWGTNVYVEDRTVDVHIRRLRKALETSGHDKMVQTVRGTGYRFSTRY

Specific function: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by phoB and phoR when phosphate is limited [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=229, Percent_Identity=91.2663755458515, Blast_Score=439, Evalue=1e-125,
Organism=Escherichia coli, GI1788394, Length=224, Percent_Identity=39.7321428571429, Blast_Score=167, Evalue=8e-43,
Organism=Escherichia coli, GI1789809, Length=232, Percent_Identity=37.0689655172414, Blast_Score=144, Evalue=6e-36,
Organism=Escherichia coli, GI1786911, Length=223, Percent_Identity=34.0807174887892, Blast_Score=139, Evalue=1e-34,
Organism=Escherichia coli, GI87082012, Length=223, Percent_Identity=35.8744394618834, Blast_Score=137, Evalue=4e-34,
Organism=Escherichia coli, GI1790860, Length=221, Percent_Identity=35.7466063348416, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1790863, Length=231, Percent_Identity=35.0649350649351, Blast_Score=134, Evalue=6e-33,
Organism=Escherichia coli, GI1786784, Length=220, Percent_Identity=32.7272727272727, Blast_Score=133, Evalue=9e-33,
Organism=Escherichia coli, GI1787375, Length=225, Percent_Identity=32.8888888888889, Blast_Score=130, Evalue=6e-32,
Organism=Escherichia coli, GI2367329, Length=229, Percent_Identity=37.117903930131, Blast_Score=127, Evalue=9e-31,
Organism=Escherichia coli, GI1790552, Length=220, Percent_Identity=32.2727272727273, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1789402, Length=226, Percent_Identity=33.6283185840708, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1787229, Length=230, Percent_Identity=30.8695652173913, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI145693140, Length=236, Percent_Identity=27.5423728813559, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1788191, Length=122, Percent_Identity=27.0491803278689, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788550, Length=109, Percent_Identity=37.6146788990826, Blast_Score=68, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR011879
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26455; Mature: 26324

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
6.1 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
5.7 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARRILVVEDEAPIREMVCFVLEQNGYQPLEAEDYDSAVTRLSEPFPDLVLLDWMLPGGS
CCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCEEEEEEECCCCC
GIQFIKHMKREAMTRDIPVMMLTARGEEEDRVRGLEVGADDYITKPFSPKELVARIKAVM
HHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHCCEEECCCCCCCCCCCHHHHHHHHHHHH
RRISPMAVEEVIEMQGLSLDPSSHRVMANEQALDMGPTEFKLLHFFMTHPERVYSREQLL
HHCCHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHH
NHVWGTNVYVEDRTVDVHIRRLRKALETSGHDKMVQTVRGTGYRFSTRY
HHHCCCCEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCEEEECCC
>Mature Secondary Structure 
ARRILVVEDEAPIREMVCFVLEQNGYQPLEAEDYDSAVTRLSEPFPDLVLLDWMLPGGS
CCEEEEEECCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCEEEEEEECCCCC
GIQFIKHMKREAMTRDIPVMMLTARGEEEDRVRGLEVGADDYITKPFSPKELVARIKAVM
HHHHHHHHHHHHHHCCCCEEEEEECCCHHHHHCCEEECCCCCCCCCCCHHHHHHHHHHHH
RRISPMAVEEVIEMQGLSLDPSSHRVMANEQALDMGPTEFKLLHFFMTHPERVYSREQLL
HHCCHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHH
NHVWGTNVYVEDRTVDVHIRRLRKALETSGHDKMVQTVRGTGYRFSTRY
HHHCCCCEEEECCCHHHHHHHHHHHHHCCCHHHHHHHHHCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]