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The map label for this gene is surA [H]

Identifier: 157368971

GI number: 157368971

Start: 802864

End: 804162

Strand: Reverse

Name: surA [H]

Synonym: Spro_0726

Alternate gene names: 157368971

Gene position: 804162-802864 (Counterclockwise)

Preceding gene: 157368972

Following gene: 157368970

Centisome position: 14.76

GC content: 55.5

Gene sequence:

>1299_bases
ATGAAGAACTGGAGAACGCTTATTCTCGGATTGGTGGTTTGTGCCAATACCGCGTTCGCAGCACCCCAAGAAGTGGATAA
AGTCGCCGCCGTCGTGGATAACGGCGTGGTCCTTGAGAGCGACGTAAGCACCCTGTTGCAGTCGGTAAAACTCAATGCAC
AGCAGGCCGGCCAGCAATTGCCGGATGACAAAACGCTTCGTCACCAGATCCTTGAGCGCCTGATTATGGATAACATCCAG
CTGCAGATGGCCAAGAAAATGGGGATCAACGTTTCTGACGCAGATCTGGACAAAGCCATCGGCAACATCGCCGCACAGAA
CAAAATGAGCATCGATCAGATGCGCAGCCGTCTGGCGTATGAAGGCCTGAACTACAACACCTACCGTTCGCAGATCCGCA
AGGAAATGCTGATTTCTGAGGTGCGTAACAATGAAGTGCGCCGCCGCGTCACTATCCTGCCGCAGGAAGTGGACTCACTG
GCCGCTCAGGTTGGCGCCCAGAACGGCAGCGATACCGAAATGAACATCAGCCACATCCTGATCCCGCTGCCGGAAAACCC
GTCGCAGGCGCAGGTAGACGACGCGGAAGCGCTGGCTAAAAAACTGATGGGTGAAATCAACGGCGGCGCCGACTTCGGCA
AGCTGGCAATCTCCTACTCTGCCGACTCCCAGGCGCTGAAAGGCGGCAACATGGGCTGGGGCAAACTGCAGGAGATCCCG
ACCCTGTTCGCCGAAAGACTGGTTAACGCCAAAAAAGGTGATGTGGTTGGGCCAATCCGCTCCGGCGTCGGCTTCCACAT
CCTGAAAGTGAATGATATCCGTGGTGCCAACCAGTCGGTGTCTGTTACCGAGGTTCACGCTCGTCACATTCTGCTGAAAC
CTTCTGTGGTACTGACTGACGATCAGGCACGTGCCAAGTTGCAAGAGGTGGCCGAAGCCATCAAGAGCGGCCGCGCCAAG
TTTGCTGACGAAGCCAAACAGCTTTCTCAGGATCCAGGTTCTGCATTGCAGGGCGGCGATCTGGGCTGGGCTTCTCCAGA
CATCTACGATCCGGCCTTCCGTGACGCGTTGATGAAGCTGAGTAAAGGCGAAGTCAGCCAACCGGTGCATTCTTCCTTCG
GCTGGCACCTGATTCAGTTGCTGGATACGCGTCAGGTAGACAAAACCGATGCGGCGCAGAAAGATCGCGCTTACCGCATG
CTGTTCAACCGCAAGTTTGCTGAAGAAGCGCAGACCTGGATGCAGGAACAACGTGCTCAGGCTTACGTGAAGATCCTTGA
CGGTAATGCACAACAATAA

Upstream 100 bases:

>100_bases
GTTCCGGCATTCTGCCTTACCAGCGTGCATTTTGATGCTTTGTAACACTTTGAAAACGAGAACTTTAACCCGCATTTGCG
GATTACATAATGGGAAATGT

Downstream 100 bases:

>100_bases
TCGCATCGTAATCACCCCCGGCGAGCCTGCCGGGGTTGGGCCGGATTTGGTGGCAGCGCTGGCGCAACAGGATTGGCCTG
TTGAACTGGTGGTGTGCGCG

Product: peptidyl-prolyl cis-trans isomerase SurA

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase surA; PPIase surA; Rotamase surA [H]

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MKNWRTLILGLVVCANTAFAAPQEVDKVAAVVDNGVVLESDVSTLLQSVKLNAQQAGQQLPDDKTLRHQILERLIMDNIQ
LQMAKKMGINVSDADLDKAIGNIAAQNKMSIDQMRSRLAYEGLNYNTYRSQIRKEMLISEVRNNEVRRRVTILPQEVDSL
AAQVGAQNGSDTEMNISHILIPLPENPSQAQVDDAEALAKKLMGEINGGADFGKLAISYSADSQALKGGNMGWGKLQEIP
TLFAERLVNAKKGDVVGPIRSGVGFHILKVNDIRGANQSVSVTEVHARHILLKPSVVLTDDQARAKLQEVAEAIKSGRAK
FADEAKQLSQDPGSALQGGDLGWASPDIYDPAFRDALMKLSKGEVSQPVHSSFGWHLIQLLDTRQVDKTDAAQKDRAYRM
LFNRKFAEEAQTWMQEQRAQAYVKILDGNAQQ

Sequences:

>Translated_432_residues
MKNWRTLILGLVVCANTAFAAPQEVDKVAAVVDNGVVLESDVSTLLQSVKLNAQQAGQQLPDDKTLRHQILERLIMDNIQ
LQMAKKMGINVSDADLDKAIGNIAAQNKMSIDQMRSRLAYEGLNYNTYRSQIRKEMLISEVRNNEVRRRVTILPQEVDSL
AAQVGAQNGSDTEMNISHILIPLPENPSQAQVDDAEALAKKLMGEINGGADFGKLAISYSADSQALKGGNMGWGKLQEIP
TLFAERLVNAKKGDVVGPIRSGVGFHILKVNDIRGANQSVSVTEVHARHILLKPSVVLTDDQARAKLQEVAEAIKSGRAK
FADEAKQLSQDPGSALQGGDLGWASPDIYDPAFRDALMKLSKGEVSQPVHSSFGWHLIQLLDTRQVDKTDAAQKDRAYRM
LFNRKFAEEAQTWMQEQRAQAYVKILDGNAQQ
>Mature_432_residues
MKNWRTLILGLVVCANTAFAAPQEVDKVAAVVDNGVVLESDVSTLLQSVKLNAQQAGQQLPDDKTLRHQILERLIMDNIQ
LQMAKKMGINVSDADLDKAIGNIAAQNKMSIDQMRSRLAYEGLNYNTYRSQIRKEMLISEVRNNEVRRRVTILPQEVDSL
AAQVGAQNGSDTEMNISHILIPLPENPSQAQVDDAEALAKKLMGEINGGADFGKLAISYSADSQALKGGNMGWGKLQEIP
TLFAERLVNAKKGDVVGPIRSGVGFHILKVNDIRGANQSVSVTEVHARHILLKPSVVLTDDQARAKLQEVAEAIKSGRAK
FADEAKQLSQDPGSALQGGDLGWASPDIYDPAFRDALMKLSKGEVSQPVHSSFGWHLIQLLDTRQVDKTDAAQKDRAYRM
LFNRKFAEEAQTWMQEQRAQAYVKILDGNAQQ

Specific function: Chaperone involved in the correct folding and assembly of outer membrane proteins. It recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Periplasm. Note=Is capable of associating with the outer membrane (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PpiC domains [H]

Homologues:

Organism=Escherichia coli, GI1786238, Length=426, Percent_Identity=73.4741784037559, Blast_Score=649, Evalue=0.0,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023034
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 47518; Mature: 47518

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: PS01096 PPIC_PPIASE_1 ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNWRTLILGLVVCANTAFAAPQEVDKVAAVVDNGVVLESDVSTLLQSVKLNAQQAGQQL
CCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEHHHHHHHHHHHHCCHHHHHCCC
PDDKTLRHQILERLIMDNIQLQMAKKMGINVSDADLDKAIGNIAAQNKMSIDQMRSRLAY
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHH
EGLNYNTYRSQIRKEMLISEVRNNEVRRRVTILPQEVDSLAAQVGAQNGSDTEMNISHIL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCEEEEEEE
IPLPENPSQAQVDDAEALAKKLMGEINGGADFGKLAISYSADSQALKGGNMGWGKLQEIP
EECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHCCCCCCCHHHHHHH
TLFAERLVNAKKGDVVGPIRSGVGFHILKVNDIRGANQSVSVTEVHARHILLKPSVVLTD
HHHHHHHHCCCCCCCCCHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHEEECCCEEEEC
DQARAKLQEVAEAIKSGRAKFADEAKQLSQDPGSALQGGDLGWASPDIYDPAFRDALMKL
CHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
SKGEVSQPVHSSFGWHLIQLLDTRQVDKTDAAQKDRAYRMLFNRKFAEEAQTWMQEQRAQ
HCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AYVKILDGNAQQ
HHHHHCCCCCCC
>Mature Secondary Structure
MKNWRTLILGLVVCANTAFAAPQEVDKVAAVVDNGVVLESDVSTLLQSVKLNAQQAGQQL
CCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCEEEHHHHHHHHHHHHCCHHHHHCCC
PDDKTLRHQILERLIMDNIQLQMAKKMGINVSDADLDKAIGNIAAQNKMSIDQMRSRLAY
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHH
EGLNYNTYRSQIRKEMLISEVRNNEVRRRVTILPQEVDSLAAQVGAQNGSDTEMNISHIL
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCEEEEEEE
IPLPENPSQAQVDDAEALAKKLMGEINGGADFGKLAISYSADSQALKGGNMGWGKLQEIP
EECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEECCCCHHHCCCCCCCHHHHHHH
TLFAERLVNAKKGDVVGPIRSGVGFHILKVNDIRGANQSVSVTEVHARHILLKPSVVLTD
HHHHHHHHCCCCCCCCCHHHCCCCEEEEEEECCCCCCCCCCHHHHHHHHEEECCCEEEEC
DQARAKLQEVAEAIKSGRAKFADEAKQLSQDPGSALQGGDLGWASPDIYDPAFRDALMKL
CHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
SKGEVSQPVHSSFGWHLIQLLDTRQVDKTDAAQKDRAYRMLFNRKFAEEAQTWMQEQRAQ
HCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AYVKILDGNAQQ
HHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA