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The map label for this gene is phnF [H]

Identifier: 157368769

GI number: 157368769

Start: 573650

End: 574378

Strand: Reverse

Name: phnF [H]

Synonym: Spro_0522

Alternate gene names: 157368769

Gene position: 574378-573650 (Counterclockwise)

Preceding gene: 157368771

Following gene: 157368768

Centisome position: 10.54

GC content: 59.67

Gene sequence:

>729_bases
ATGATGGACTTATCTAGACATCCGACCAGTTTCCCTACCCGCTACCAGCAAATCGCCGCGCAGCTAGAGCAAGAGCTGCG
TACCCAATACCGCTGCGGTGACTATCTGCCTTCCGAACAACAGCTGGCAGAGCGCTATCAGGTTAATCGCCATACCCTGC
GCCGCGCGGTTGACCAATTGGTGGATCGCGGCTGGCTGCAACGTCGACACGGCATCGGCATTTTGGTGCTGATGCGCCCC
TATGACTATCCGCTGCATGCCAATACCCGGTTCAGCCAGAACCTGTTCGAGCAGGGCAGCCACCCCACCAGTGAGCGCTT
ACTCGCTGTATTACGCCCGTGTAATGGGCATGTTGCCAGTGCACTGTCGCGTGAAGAAGGCGAAACGGTGATCCACCTGC
GTACCCTACGCCGGGTCAACGGCGTGCCGATGAGCCTGATCGACCATTATCTGCCCGATCTGGACTGGTGGCCGGCGTTA
CAGCAGTTCCACAGCGGTTCATTGCACGAATTTATCGAACTCAACATCCACCAGCCGCTGACCCGCAAGCAGACGCGCAT
CAGCGCACGCCGCGCGCAGGCTAAAGAGAGCCGGTTGCTGGAAATAGCCACCCACGCGCCGCTGCTGTGCGTGCGCACCC
TCAACGTCTGCACCGGCAGTGACAGCGTGGCGGAATACTCCGTCAGCCTGGCACGCGCCGACATGATTGAACTGACCATG
GAGCACTGA

Upstream 100 bases:

>100_bases
CCCCGGCAGAATAACGCCAACTTCACCAAAGGGTACACATCATGCAACGCCAACCATCAGCATCCTGTGAATGGGTATTC
GGCACGCCGAGGTTTTTATT

Downstream 100 bases:

>100_bases
ATGCAAGCCTTACAGCCGAGACAACGCTGGATGTCGGTATTGGCGCACAGCCAGCCGGACCAGTTGCGCAGCCACTGGCA
GGCGCTGAACCTCAGCCCGC

Product: phosphonate metabolism transcriptional regulator PhnF

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 242

Protein sequence:

>242_residues
MMDLSRHPTSFPTRYQQIAAQLEQELRTQYRCGDYLPSEQQLAERYQVNRHTLRRAVDQLVDRGWLQRRHGIGILVLMRP
YDYPLHANTRFSQNLFEQGSHPTSERLLAVLRPCNGHVASALSREEGETVIHLRTLRRVNGVPMSLIDHYLPDLDWWPAL
QQFHSGSLHEFIELNIHQPLTRKQTRISARRAQAKESRLLEIATHAPLLCVRTLNVCTGSDSVAEYSVSLARADMIELTM
EH

Sequences:

>Translated_242_residues
MMDLSRHPTSFPTRYQQIAAQLEQELRTQYRCGDYLPSEQQLAERYQVNRHTLRRAVDQLVDRGWLQRRHGIGILVLMRP
YDYPLHANTRFSQNLFEQGSHPTSERLLAVLRPCNGHVASALSREEGETVIHLRTLRRVNGVPMSLIDHYLPDLDWWPAL
QQFHSGSLHEFIELNIHQPLTRKQTRISARRAQAKESRLLEIATHAPLLCVRTLNVCTGSDSVAEYSVSLARADMIELTM
EH
>Mature_242_residues
MMDLSRHPTSFPTRYQQIAAQLEQELRTQYRCGDYLPSEQQLAERYQVNRHTLRRAVDQLVDRGWLQRRHGIGILVLMRP
YDYPLHANTRFSQNLFEQGSHPTSERLLAVLRPCNGHVASALSREEGETVIHLRTLRRVNGVPMSLIDHYLPDLDWWPAL
QQFHSGSLHEFIELNIHQPLTRKQTRISARRAQAKESRLLEIATHAPLLCVRTLNVCTGSDSVAEYSVSLARADMIELTM
EH

Specific function: Belongs to an operon involved in alkylphosphonate uptake and C-P lyase. Exact function not known. By similarity could be a transcriptional regulator [H]

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790540, Length=241, Percent_Identity=71.3692946058091, Blast_Score=355, Evalue=2e-99,
Organism=Escherichia coli, GI1790118, Length=221, Percent_Identity=29.4117647058824, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1786950, Length=235, Percent_Identity=28.0851063829787, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1788418, Length=214, Percent_Identity=25.2336448598131, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012702
- InterPro:   IPR000524
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 27993; Mature: 27993

Theoretical pI: Translated: 8.35; Mature: 8.35

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMDLSRHPTSFPTRYQQIAAQLEQELRTQYRCGDYLPSEQQLAERYQVNRHTLRRAVDQL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
VDRGWLQRRHGIGILVLMRPYDYPLHANTRFSQNLFEQGSHPTSERLLAVLRPCNGHVAS
HHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHH
ALSREEGETVIHLRTLRRVNGVPMSLIDHYLPDLDWWPALQQFHSGSLHEFIELNIHQPL
HHHHHCCCEEEHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHCCCCCCH
TRKQTRISARRAQAKESRLLEIATHAPLLCVRTLNVCTGSDSVAEYSVSLARADMIELTM
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHEE
EH
CC
>Mature Secondary Structure
MMDLSRHPTSFPTRYQQIAAQLEQELRTQYRCGDYLPSEQQLAERYQVNRHTLRRAVDQL
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
VDRGWLQRRHGIGILVLMRPYDYPLHANTRFSQNLFEQGSHPTSERLLAVLRPCNGHVAS
HHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHH
ALSREEGETVIHLRTLRRVNGVPMSLIDHYLPDLDWWPALQQFHSGSLHEFIELNIHQPL
HHHHHCCCEEEHHHHHHHHCCCCHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHCCCCCCH
TRKQTRISARRAQAKESRLLEIATHAPLLCVRTLNVCTGSDSVAEYSVSLARADMIELTM
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHEE
EH
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2155230; 1840580; 7610040; 9278503 [H]