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The map label for this gene is speF [H]

Identifier: 157368756

GI number: 157368756

Start: 561828

End: 563999

Strand: Reverse

Name: speF [H]

Synonym: Spro_0509

Alternate gene names: 157368756

Gene position: 563999-561828 (Counterclockwise)

Preceding gene: 157368759

Following gene: 157368755

Centisome position: 10.35

GC content: 51.75

Gene sequence:

>2172_bases
ATGATTAAAATGAATAAATTAAAAATTGCCGCTAATAGCAAAACATTAAGTTGCTTCGAAACCACTCGCGAAGTTGTCGA
TGTACACCAGAGTGATTTTAATGATATTGCCGCCATCGTATTGTCGGTGGAAGACGTCACGCAGGGCATGGTGGCTCACC
TCGAAGAGATCGGCCTGAATATCCCGTTATTCGTGGCGGTTTGCTGCGAAGAAGAGCTGGACAACGCCATACTGCCTGCC
CTGCATGGCGTATTTGAACTCTGTGGCAAGAACACCCAGTTCTATGGCAAGCAGCTGGAAGCTGCGGCCGTAAAATACGA
AAGCGAACTGCTGCCACCTTTCTTTAATACGCTGACCCAGTATGTCGAAATGGGTAACGCCACCTTTGCTTGCCCTGGGC
ATCAGGGGGGCGAATTCTTCCGTAAGCATCCGGCCGGGCGTCAGTTCTTTGACTTCTTTGGCGAGACCCTTTTCCGTTCC
GATATGTGCAACGCGGACGTCAAACTGGGTGATTTGTTGATCCATGAAGGCGCCCCCTGCGCGGCGCAGCAGCATGCCGC
CAAAGTGTTTAACGCCGATAAAACCTATTTCGTTCTTAACGGCACCTCCGCCTCAAACAAGGTGGCAACCAACGCCCTGC
TGACGCGCGGTGACCTGGTGCTGTTCGACCGCAACAACCATAAATCCAATCATCATGGCGCGCTGATCCAGGCGGGGGCA
ACACCGGTGTATCTGGAAACCGCCCGCAACCCGTTTGGCTTTATCGGCGGCATTGACGCGCACTGCTTTGAAGAACGCTA
CTTACGCCAGCAGATCCGCGAGGTCGCGCCGGAGCGCGCCAATGAAGCCAGACCTTTCCGCCTGGCGATCATTCAGTTGG
GCACCTATGACGGCACCATTTATAACGCCCGTCAGGTGGTCGATAAAATTGGTCATCTGTGCGATTACATCCTGTTCGAC
TCGGCCTGGGTCGGCTATGAGCAATTCATTCCAATGATGAAGGACTGCTCTCCGTTGCTGCTCGAGCTAAACGAAAACGA
CCCTGGGATCATTGTGACCCAGTCCGTCCACAAGCAGCAGGCCGGCTTCTCGCAGACCTCGCAAATCCATAAGAAAGACA
AGCATATCAAGGGACAAGATCGCTATTGCAACCACAAACGCTTTAACAATGCCTTTATGCTGCACGCTTCCACCAGCCCG
TTTTACCCGCTGTTCGCCGCACTGGACGTTAACGCCAAAATGCATGAGGGCAAAAGCGGCCGACGCCTGTGGAAAGAATG
CGTTCGCGTAGGCATTGAGGCGCGCAAGATGCTGCTGGAGACCTGCAGCTTAATCAAGCCCTTTGTGCCGGACCAAATCG
ACGGTAAAGCCTGGCAGTCTTATGATACCGAGACGATGTCCAACGATTTGCGCTTCTTCAACTTCATTCCCGGTGAAAAA
TGGCATGCCTTTGAAGGCTATGCCCAATCGCAGTATTTTGTCGACCCGTGCAAACTGCTGCTCACCACGCCGGGCATTGA
TACGGCAAGCGGTAACTACAGCGATTTCGGTATTCCGGCGACCATTCTGGCCAACTATCTGCGCGAAAACGGCATAGTAC
CGGAGAAATGCGACCTTAATTCGATCCTGTTCCTGCTGACTCCGGCCGAAGACATCGCCAAGATGCAGCATTTGGTGGCG
CTGATTGCCCGCTTTGAAAAACATATTGAGCAAGATTCTTTAATTAGTGATGTCTTGCCTGCGGTTTATAAAAACAATCA
GCAGCGCTATGAAAATTATACCCTGCGCCAACTCTGCCAGGAAATGCACGACCTTTATGTCAGCTACGACGTTAAAGAAC
TGCAGAAAGAAATGTTCAGGAAGAGTTATTTCCCTCATGTGGCAATGAATCCACAAGACGCCAACACCGAATTTGTCCGC
GGTAATGTGGAATTGGTTTCTCTGGCGAAAGCCGAAGGCAGAATTGCCGCCGAAGGTGCCTTGCCTTATCCCCCAGGCGT
ATTGTGCGTTGTCCCAGGGGAAGTGTGGGGTGGTGCTGCACAGCGTTATTTCCTGGCATTGGAAGAAGGCATCAATTTAT
TGCCCGGTTTCGCACCGGAATTACAGGGCGTGTATATCCAGCAGGATGAAGATGGCTGGAACCGTGCTTACGGTTACGTA
ATGAAAAATTAA

Upstream 100 bases:

>100_bases
CTGCGATTAAGCATGACTGCGTTCTTCTCACGCCTTTATTTTAGTGAGGGCATTAGCGACAGGGTTATTAACCTGCCGGC
GGGATGCCTTTGCCTGAAGA

Downstream 100 bases:

>100_bases
TCACCTTACAAGGCGGTGAATTTTATTCACCGCCCGGATCGTATTATAAAAGAGAGAATGATCATGAGTAAGTCCAATAA
TAAAATGGGGGTCGTACAGC

Product: ornithine decarboxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 723; Mature: 723

Protein sequence:

>723_residues
MIKMNKLKIAANSKTLSCFETTREVVDVHQSDFNDIAAIVLSVEDVTQGMVAHLEEIGLNIPLFVAVCCEEELDNAILPA
LHGVFELCGKNTQFYGKQLEAAAVKYESELLPPFFNTLTQYVEMGNATFACPGHQGGEFFRKHPAGRQFFDFFGETLFRS
DMCNADVKLGDLLIHEGAPCAAQQHAAKVFNADKTYFVLNGTSASNKVATNALLTRGDLVLFDRNNHKSNHHGALIQAGA
TPVYLETARNPFGFIGGIDAHCFEERYLRQQIREVAPERANEARPFRLAIIQLGTYDGTIYNARQVVDKIGHLCDYILFD
SAWVGYEQFIPMMKDCSPLLLELNENDPGIIVTQSVHKQQAGFSQTSQIHKKDKHIKGQDRYCNHKRFNNAFMLHASTSP
FYPLFAALDVNAKMHEGKSGRRLWKECVRVGIEARKMLLETCSLIKPFVPDQIDGKAWQSYDTETMSNDLRFFNFIPGEK
WHAFEGYAQSQYFVDPCKLLLTTPGIDTASGNYSDFGIPATILANYLRENGIVPEKCDLNSILFLLTPAEDIAKMQHLVA
LIARFEKHIEQDSLISDVLPAVYKNNQQRYENYTLRQLCQEMHDLYVSYDVKELQKEMFRKSYFPHVAMNPQDANTEFVR
GNVELVSLAKAEGRIAAEGALPYPPGVLCVVPGEVWGGAAQRYFLALEEGINLLPGFAPELQGVYIQQDEDGWNRAYGYV
MKN

Sequences:

>Translated_723_residues
MIKMNKLKIAANSKTLSCFETTREVVDVHQSDFNDIAAIVLSVEDVTQGMVAHLEEIGLNIPLFVAVCCEEELDNAILPA
LHGVFELCGKNTQFYGKQLEAAAVKYESELLPPFFNTLTQYVEMGNATFACPGHQGGEFFRKHPAGRQFFDFFGETLFRS
DMCNADVKLGDLLIHEGAPCAAQQHAAKVFNADKTYFVLNGTSASNKVATNALLTRGDLVLFDRNNHKSNHHGALIQAGA
TPVYLETARNPFGFIGGIDAHCFEERYLRQQIREVAPERANEARPFRLAIIQLGTYDGTIYNARQVVDKIGHLCDYILFD
SAWVGYEQFIPMMKDCSPLLLELNENDPGIIVTQSVHKQQAGFSQTSQIHKKDKHIKGQDRYCNHKRFNNAFMLHASTSP
FYPLFAALDVNAKMHEGKSGRRLWKECVRVGIEARKMLLETCSLIKPFVPDQIDGKAWQSYDTETMSNDLRFFNFIPGEK
WHAFEGYAQSQYFVDPCKLLLTTPGIDTASGNYSDFGIPATILANYLRENGIVPEKCDLNSILFLLTPAEDIAKMQHLVA
LIARFEKHIEQDSLISDVLPAVYKNNQQRYENYTLRQLCQEMHDLYVSYDVKELQKEMFRKSYFPHVAMNPQDANTEFVR
GNVELVSLAKAEGRIAAEGALPYPPGVLCVVPGEVWGGAAQRYFLALEEGINLLPGFAPELQGVYIQQDEDGWNRAYGYV
MKN
>Mature_723_residues
MIKMNKLKIAANSKTLSCFETTREVVDVHQSDFNDIAAIVLSVEDVTQGMVAHLEEIGLNIPLFVAVCCEEELDNAILPA
LHGVFELCGKNTQFYGKQLEAAAVKYESELLPPFFNTLTQYVEMGNATFACPGHQGGEFFRKHPAGRQFFDFFGETLFRS
DMCNADVKLGDLLIHEGAPCAAQQHAAKVFNADKTYFVLNGTSASNKVATNALLTRGDLVLFDRNNHKSNHHGALIQAGA
TPVYLETARNPFGFIGGIDAHCFEERYLRQQIREVAPERANEARPFRLAIIQLGTYDGTIYNARQVVDKIGHLCDYILFD
SAWVGYEQFIPMMKDCSPLLLELNENDPGIIVTQSVHKQQAGFSQTSQIHKKDKHIKGQDRYCNHKRFNNAFMLHASTSP
FYPLFAALDVNAKMHEGKSGRRLWKECVRVGIEARKMLLETCSLIKPFVPDQIDGKAWQSYDTETMSNDLRFFNFIPGEK
WHAFEGYAQSQYFVDPCKLLLTTPGIDTASGNYSDFGIPATILANYLRENGIVPEKCDLNSILFLLTPAEDIAKMQHLVA
LIARFEKHIEQDSLISDVLPAVYKNNQQRYENYTLRQLCQEMHDLYVSYDVKELQKEMFRKSYFPHVAMNPQDANTEFVR
GNVELVSLAKAEGRIAAEGALPYPPGVLCVVPGEVWGGAAQRYFLALEEGINLLPGFAPELQGVYIQQDEDGWNRAYGYV
MKN

Specific function: Spermidine biosynthesis from ornithine. [C]

COG id: COG1982

COG function: function code E; Arginine/lysine/ornithine decarboxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1786909, Length=719, Percent_Identity=72.3226703755216, Blast_Score=1118, Evalue=0.0,
Organism=Escherichia coli, GI87082193, Length=719, Percent_Identity=71.9054242002782, Blast_Score=1098, Evalue=0.0,
Organism=Escherichia coli, GI221142684, Length=678, Percent_Identity=31.5634218289086, Blast_Score=339, Evalue=4e-94,
Organism=Escherichia coli, GI1790573, Length=669, Percent_Identity=33.4828101644245, Blast_Score=336, Evalue=3e-93,
Organism=Escherichia coli, GI1786384, Length=693, Percent_Identity=31.1688311688312, Blast_Score=320, Evalue=1e-88,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR005308
- InterPro:   IPR011193
- InterPro:   IPR000310
- InterPro:   IPR008286
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01276 OKR_DC_1; PF03711 OKR_DC_1_C; PF03709 OKR_DC_1_N [H]

EC number: =4.1.1.17 [H]

Molecular weight: Translated: 81366; Mature: 81366

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: PS00703 OKR_DC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKMNKLKIAANSKTLSCFETTREVVDVHQSDFNDIAAIVLSVEDVTQGMVAHLEEIGLN
CCCEEEEEEEECCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
IPLFVAVCCEEELDNAILPALHGVFELCGKNTQFYGKQLEAAAVKYESELLPPFFNTLTQ
CHHHHEEHHHHHHCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHH
YVEMGNATFACPGHQGGEFFRKHPAGRQFFDFFGETLFRSDMCNADVKLGDLLIHEGAPC
HHHCCCCEEECCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCEECCEEEECCCCC
AAQQHAAKVFNADKTYFVLNGTSASNKVATNALLTRGDLVLFDRNNHKSNHHGALIQAGA
HHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHEECCCEEEEECCCCCCCCCCCEEECCC
TPVYLETARNPFGFIGGIDAHCFEERYLRQQIREVAPERANEARPFRLAIIQLGTYDGTI
CEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCHHCCCCCCCEEEEEEEEECCCCCH
YNARQVVDKIGHLCDYILFDSAWVGYEQFIPMMKDCSPLLLELNENDPGIIVTQSVHKQQ
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEEEECCCCCCEEEECHHHHHH
AGFSQTSQIHKKDKHIKGQDRYCNHKRFNNAFMLHASTSPFYPLFAALDVNAKMHEGKSG
CCCHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEEECCCHHCCCCCH
RRLWKECVRVGIEARKMLLETCSLIKPFVPDQIDGKAWQSYDTETMSNDLRFFNFIPGEK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCCCCHHHHCCCEEEECCCCCC
WHAFEGYAQSQYFVDPCKLLLTTPGIDTASGNYSDFGIPATILANYLRENGIVPEKCDLN
CCCCCCCCCCCEECCCHHHEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCC
SILFLLTPAEDIAKMQHLVALIARFEKHIEQDSLISDVLPAVYKNNQQRYENYTLRQLCQ
CEEEEEECHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHCHHHHHHHH
EMHDLYVSYDVKELQKEMFRKSYFPHVAMNPQDANTEFVRGNVELVSLAKAEGRIAAEGA
HHHHHHHCCCHHHHHHHHHHHHCCCCEECCCCCCCCCEEECCEEEEEEECCCCCEEECCC
LPYPPGVLCVVPGEVWGGAAQRYFLALEEGINLLPGFAPELQGVYIQQDEDGWNRAYGYV
CCCCCCEEEEECCHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCCEE
MKN
ECC
>Mature Secondary Structure
MIKMNKLKIAANSKTLSCFETTREVVDVHQSDFNDIAAIVLSVEDVTQGMVAHLEEIGLN
CCCEEEEEEEECCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
IPLFVAVCCEEELDNAILPALHGVFELCGKNTQFYGKQLEAAAVKYESELLPPFFNTLTQ
CHHHHEEHHHHHHCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHH
YVEMGNATFACPGHQGGEFFRKHPAGRQFFDFFGETLFRSDMCNADVKLGDLLIHEGAPC
HHHCCCCEEECCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCEECCEEEECCCCC
AAQQHAAKVFNADKTYFVLNGTSASNKVATNALLTRGDLVLFDRNNHKSNHHGALIQAGA
HHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHEECCCEEEEECCCCCCCCCCCEEECCC
TPVYLETARNPFGFIGGIDAHCFEERYLRQQIREVAPERANEARPFRLAIIQLGTYDGTI
CEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCHHCCCCCCCEEEEEEEEECCCCCH
YNARQVVDKIGHLCDYILFDSAWVGYEQFIPMMKDCSPLLLELNENDPGIIVTQSVHKQQ
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEEEECCCCCCEEEECHHHHHH
AGFSQTSQIHKKDKHIKGQDRYCNHKRFNNAFMLHASTSPFYPLFAALDVNAKMHEGKSG
CCCHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEEECCCHHCCCCCH
RRLWKECVRVGIEARKMLLETCSLIKPFVPDQIDGKAWQSYDTETMSNDLRFFNFIPGEK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCCCCHHHHCCCEEEECCCCCC
WHAFEGYAQSQYFVDPCKLLLTTPGIDTASGNYSDFGIPATILANYLRENGIVPEKCDLN
CCCCCCCCCCCEECCCHHHEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCC
SILFLLTPAEDIAKMQHLVALIARFEKHIEQDSLISDVLPAVYKNNQQRYENYTLRQLCQ
CEEEEEECHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHCHHHHHHHH
EMHDLYVSYDVKELQKEMFRKSYFPHVAMNPQDANTEFVRGNVELVSLAKAEGRIAAEGA
HHHHHHHCCCHHHHHHHHHHHHCCCCEECCCCCCCCCEEECCEEEEEEECCCCCEEECCC
LPYPPGVLCVVPGEVWGGAAQRYFLALEEGINLLPGFAPELQGVYIQQDEDGWNRAYGYV
CCCCCCEEEEECCHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCCCCCCCEE
MKN
ECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1939141; 8905232; 9278503 [H]