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The map label for this gene is nsrR

Identifier: 157368684

GI number: 157368684

Start: 489086

End: 489511

Strand: Direct

Name: nsrR

Synonym: Spro_0437

Alternate gene names: 157368684

Gene position: 489086-489511 (Clockwise)

Preceding gene: 157368683

Following gene: 157368685

Centisome position: 8.98

GC content: 53.29

Gene sequence:

>426_bases
GTGCAGTTAACAAGTTTTACTGATTACGGCCTGCGGGCGTTGATCTACATGGCCTCGCTGCCACCGGACAAAATGACCAG
CATCTCGGAAGTTACCGAGGTCTACGGCGTGTCCAGAAACCATATGGTAAAGATCATCAATCAGTTAAGCCGGGTTGGGT
TTGTAACCGCAGTGCGCGGTAAGAACGGCGGCATCCGTTTAGGCAAACCGGCCGAAACCATTCGCCTCGGCGACGTAGTC
AGGGCGCTGGAGCCGCTGTCACTGGTTAACTGCAACAGTACTTTCTGCCACATAACCCCTGCTTGCCGCCTGAAACAGGT
GCTCCAACAGGGCGTACAGAATTTCCTTGAAGAGCTGGACAGCCACACGCTGGCCGATATGGTCGAAGACAATCCATCGC
TCTACAAGCTATTGCTTGTCGAATAA

Upstream 100 bases:

>100_bases
GCGGCGAACTCTCTGGCTGGTTTATTATCCAATAAGTAATCTTTTGAATAATGCCGAAAATCGGCGTATCAGACGGGTAA
AATGATACCCAGAGGTAGAT

Downstream 100 bases:

>100_bases
AGCGTCGCTGAGAAGACAAGGCTCAGCGGCACCCTGCTGATGACAACGGAGGAACCGCAATGTCACAAGATCCATTCCTG
GAACGAGAAGCAGAAAAATA

Product: transcriptional repressor NsrR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 141; Mature: 141

Protein sequence:

>141_residues
MQLTSFTDYGLRALIYMASLPPDKMTSISEVTEVYGVSRNHMVKIINQLSRVGFVTAVRGKNGGIRLGKPAETIRLGDVV
RALEPLSLVNCNSTFCHITPACRLKQVLQQGVQNFLEELDSHTLADMVEDNPSLYKLLLVE

Sequences:

>Translated_141_residues
MQLTSFTDYGLRALIYMASLPPDKMTSISEVTEVYGVSRNHMVKIINQLSRVGFVTAVRGKNGGIRLGKPAETIRLGDVV
RALEPLSLVNCNSTFCHITPACRLKQVLQQGVQNFLEELDSHTLADMVEDNPSLYKLLLVE
>Mature_141_residues
MQLTSFTDYGLRALIYMASLPPDKMTSISEVTEVYGVSRNHMVKIINQLSRVGFVTAVRGKNGGIRLGKPAETIRLGDVV
RALEPLSLVNCNSTFCHITPACRLKQVLQQGVQNFLEELDSHTLADMVEDNPSLYKLLLVE

Specific function: Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress. May require iron for activity

COG id: COG1959

COG function: function code K; Predicted transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH rrf2-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI1790621, Length=141, Percent_Identity=82.9787234042553, Blast_Score=246, Evalue=6e-67,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NSRR_SERP5 (A8G8V5)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001476673.1
- ProteinModelPortal:   A8G8V5
- SMR:   A8G8V5
- STRING:   A8G8V5
- GeneID:   5604675
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_0437
- eggNOG:   COG1959
- HOGENOM:   HBG725923
- OMA:   ITNSCQF
- ProtClustDB:   PRK11014
- BioCyc:   SPRO399741:SPRO_0437-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_01177
- InterPro:   IPR000944
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- TIGRFAMs:   TIGR00738

Pfam domain/function: PF02082 Rrf2

EC number: NA

Molecular weight: Translated: 15650; Mature: 15650

Theoretical pI: Translated: 7.44; Mature: 7.44

Prosite motif: PS01332 HTH_RRF2_1; PS51197 HTH_RRF2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLTSFTDYGLRALIYMASLPPDKMTSISEVTEVYGVSRNHMVKIINQLSRVGFVTAVRG
CCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEEEC
KNGGIRLGKPAETIRLGDVVRALEPLSLVNCNSTFCHITPACRLKQVLQQGVQNFLEELD
CCCCEECCCCHHHHHHHHHHHHHCCHHEECCCCCEEEECHHHHHHHHHHHHHHHHHHHHH
SHTLADMVEDNPSLYKLLLVE
HHHHHHHHCCCCCEEEEEECC
>Mature Secondary Structure
MQLTSFTDYGLRALIYMASLPPDKMTSISEVTEVYGVSRNHMVKIINQLSRVGFVTAVRG
CCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHEEEEC
KNGGIRLGKPAETIRLGDVVRALEPLSLVNCNSTFCHITPACRLKQVLQQGVQNFLEELD
CCCCEECCCCHHHHHHHHHHHHHCCHHEECCCCCEEEECHHHHHHHHHHHHHHHHHHHHH
SHTLADMVEDNPSLYKLLLVE
HHHHHHHHCCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA