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The map label for this gene is trkH [H]

Identifier: 157368514

GI number: 157368514

Start: 296115

End: 297566

Strand: Direct

Name: trkH [H]

Synonym: Spro_0265

Alternate gene names: 157368514

Gene position: 296115-297566 (Clockwise)

Preceding gene: 157368513

Following gene: 157368515

Centisome position: 5.43

GC content: 54.75

Gene sequence:

>1452_bases
ATGCATTTTCGCGCTATAACCCGTATCGTTGGTTTGCTGGTCATCCTGTTCTCCGGGACGATGTTTATTCCTGGTCTGGT
GGCATTGATATACCGCGATGGGGCGGGGCGGGCATTCAGCCAGACCTTCTTTGTGGCGGTAACCATCGGCCTGATGCTGT
GGTGGCCTAACCGTAAACAAAAGCATGAGCTGAAGCCACGAGAAGGTTTTCTGATTGTGGTGCTGTTCTGGACGGTGCTG
GGCAGCGTCGGGGCATTACCGTTTTTATTTTCGGAGCGGCCTAATCTTTCGCTGACCGATGCCTTCTTCGAATCGTTTTC
CGGTTTAACCACCACCGGGGCTACCACGCTGGTGGGGCTGGACTCACTACCCAAAGCCATTTTGTTCTATCGGCAGATGC
TGCAATGGATGGGCGGGATGGGGATCATTGTGTTGGCAGTGGCGATACTGCCGATCCTCGGCGTCGGCGGCATGCAGCTG
TACCGCGCAGAAATGCCAGGCCCGCTGAAAGATAATAAAATGCGCCCACGCATTGCCGAAACGGCCAAAACCCTGTGGCT
GATTTATGTCCTGTTGACTATTGCCTGTGCGCTGGCACTTTGGGGCGCTGGCATGTCGGTGTTTGACGCCATCGGCCACA
GTTTCTCGACCATCGCTATTGGCGGTTTCTCCACCCATGACGCCAGCATCGGTTATTACGCCAGTCCGACCATCAACACT
ATCATTGCTATTTTCCTGCTGATCTCCGGTTGTAACTATGGCTTGCACTTCGCCTTGCTGAGCGGCCGCAGTCTAAAAGT
GTATTGGCGTGATCCTGAGTTTCGCATGTTTATTGCCGTGCAGTTGACGCTGGTAGTGGTGTGTACCGCCGTGCTGTGGG
GGCATGGTGTCTACAAAACCGGTATGGAAACGGTCAATCAGGCGTTCTTCCAGGTGGTGTCGATGGCGACAACGGCGGGC
TTTACCACTGACAGCATTGCCAAATGGCCGTTATTCCTGCCGATGCTGTTGCTGTGTTCTGCATTTATTGGTGGCTGTGC
CGGCTCGACCGGTGGCGGCCTGAAGGTGATTCGCATTCTGCTGCTGTATTTACAGGGCTCGCGTGAGCTAAAAAGGCTGG
TGCACCCTAATGCGGTTTACACTATCAAGTTGGGTAACCGCGCGCTGCCGGAACGTATCCTGGAGGCGGTATGGGGGTTC
TTCTCTGCTTATGCGCTGGTGTTTATCGTCAGCATGCTGGCGATTATCGCCACCGGCGTTGATGATTTCTCTGCCTTTGC
TGCCGTAACGGCGACGCTGAACAACCTTGGACCAGGGCTGGGAGTGGTTGCGGATAACTTCACTACTATGCCTGCACCGG
CGAAGTGGATCCTGGTTCTGACGATGCTGTTCGGGCGCCTTGAGGTCTTTACACTGCTGGTTCTGTTTACGCCGACATTC
TGGCGTGAATGA

Upstream 100 bases:

>100_bases
GCGTTTGGGAATAAATTACGTGATCTTAGTCGCGGTAATTTGCAATTAACCCCCATTTCGCAATAATTCCCCCAACTGAA
TTGCTAAGGATCGTGCTGAA

Downstream 100 bases:

>100_bases
TCCTGATAGAAGGAGTAACGCCGTGAAGGCACTGATTCTTTATTCTAGCCGTGATGGGCAAACACGTTCTATTGCTTCTT
ATATAGCAAACAAATTGCAG

Product: potassium transporter

Products: Proton [Cytoplasm]; K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 483; Mature: 483

Protein sequence:

>483_residues
MHFRAITRIVGLLVILFSGTMFIPGLVALIYRDGAGRAFSQTFFVAVTIGLMLWWPNRKQKHELKPREGFLIVVLFWTVL
GSVGALPFLFSERPNLSLTDAFFESFSGLTTTGATTLVGLDSLPKAILFYRQMLQWMGGMGIIVLAVAILPILGVGGMQL
YRAEMPGPLKDNKMRPRIAETAKTLWLIYVLLTIACALALWGAGMSVFDAIGHSFSTIAIGGFSTHDASIGYYASPTINT
IIAIFLLISGCNYGLHFALLSGRSLKVYWRDPEFRMFIAVQLTLVVVCTAVLWGHGVYKTGMETVNQAFFQVVSMATTAG
FTTDSIAKWPLFLPMLLLCSAFIGGCAGSTGGGLKVIRILLLYLQGSRELKRLVHPNAVYTIKLGNRALPERILEAVWGF
FSAYALVFIVSMLAIIATGVDDFSAFAAVTATLNNLGPGLGVVADNFTTMPAPAKWILVLTMLFGRLEVFTLLVLFTPTF
WRE

Sequences:

>Translated_483_residues
MHFRAITRIVGLLVILFSGTMFIPGLVALIYRDGAGRAFSQTFFVAVTIGLMLWWPNRKQKHELKPREGFLIVVLFWTVL
GSVGALPFLFSERPNLSLTDAFFESFSGLTTTGATTLVGLDSLPKAILFYRQMLQWMGGMGIIVLAVAILPILGVGGMQL
YRAEMPGPLKDNKMRPRIAETAKTLWLIYVLLTIACALALWGAGMSVFDAIGHSFSTIAIGGFSTHDASIGYYASPTINT
IIAIFLLISGCNYGLHFALLSGRSLKVYWRDPEFRMFIAVQLTLVVVCTAVLWGHGVYKTGMETVNQAFFQVVSMATTAG
FTTDSIAKWPLFLPMLLLCSAFIGGCAGSTGGGLKVIRILLLYLQGSRELKRLVHPNAVYTIKLGNRALPERILEAVWGF
FSAYALVFIVSMLAIIATGVDDFSAFAAVTATLNNLGPGLGVVADNFTTMPAPAKWILVLTMLFGRLEVFTLLVLFTPTF
WRE
>Mature_483_residues
MHFRAITRIVGLLVILFSGTMFIPGLVALIYRDGAGRAFSQTFFVAVTIGLMLWWPNRKQKHELKPREGFLIVVLFWTVL
GSVGALPFLFSERPNLSLTDAFFESFSGLTTTGATTLVGLDSLPKAILFYRQMLQWMGGMGIIVLAVAILPILGVGGMQL
YRAEMPGPLKDNKMRPRIAETAKTLWLIYVLLTIACALALWGAGMSVFDAIGHSFSTIAIGGFSTHDASIGYYASPTINT
IIAIFLLISGCNYGLHFALLSGRSLKVYWRDPEFRMFIAVQLTLVVVCTAVLWGHGVYKTGMETVNQAFFQVVSMATTAG
FTTDSIAKWPLFLPMLLLCSAFIGGCAGSTGGGLKVIRILLLYLQGSRELKRLVHPNAVYTIKLGNRALPERILEAVWGF
FSAYALVFIVSMLAIIATGVDDFSAFAAVTATLNNLGPGLGVVADNFTTMPAPAKWILVLTMLFGRLEVFTLLVLFTPTF
WRE

Specific function: Low-affinity potassium transport system. Interacts with trk system potassium uptake protein trkA and requires trkE for transport activity [H]

COG id: COG0168

COG function: function code P; Trk-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trkH potassium transport family [H]

Homologues:

Organism=Escherichia coli, GI48994987, Length=483, Percent_Identity=89.8550724637681, Blast_Score=832, Evalue=0.0,
Organism=Escherichia coli, GI1787626, Length=482, Percent_Identity=40.2489626556017, Blast_Score=387, Evalue=1e-109,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003445
- InterPro:   IPR004772 [H]

Pfam domain/function: PF02386 TrkH [H]

EC number: NA

Molecular weight: Translated: 52820; Mature: 52820

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHFRAITRIVGLLVILFSGTMFIPGLVALIYRDGAGRAFSQTFFVAVTIGLMLWWPNRKQ
CCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
KHELKPREGFLIVVLFWTVLGSVGALPFLFSERPNLSLTDAFFESFSGLTTTGATTLVGL
CCCCCCCCCHHHHHHHHHHHHHHCCCCHHHCCCCCCCHHHHHHHHHCCCCCCCCHHHHHH
DSLPKAILFYRQMLQWMGGMGIIVLAVAILPILGVGGMQLYRAEMPGPLKDNKMRPRIAE
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCHHHH
TAKTLWLIYVLLTIACALALWGAGMSVFDAIGHSFSTIAIGGFSTHDASIGYYASPTINT
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCEEEECCCCCCCCCCCEECCCHHHH
IIAIFLLISGCNYGLHFALLSGRSLKVYWRDPEFRMFIAVQLTLVVVCTAVLWGHGVYKT
HHHHHHHHHCCCCCEEEEEECCCEEEEEEECCCEEEHHHHHHHHHHHHHHHHHCCCHHHH
GMETVNQAFFQVVSMATTAGFTTDSIAKWPLFLPMLLLCSAFIGGCAGSTGGGLKVIRIL
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
LLYLQGSRELKRLVHPNAVYTIKLGNRALPERILEAVWGFFSAYALVFIVSMLAIIATGV
HHHHCCCHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DDFSAFAAVTATLNNLGPGLGVVADNFTTMPAPAKWILVLTMLFGRLEVFTLLVLFTPTF
CHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHH
WRE
CCC
>Mature Secondary Structure
MHFRAITRIVGLLVILFSGTMFIPGLVALIYRDGAGRAFSQTFFVAVTIGLMLWWPNRKQ
CCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
KHELKPREGFLIVVLFWTVLGSVGALPFLFSERPNLSLTDAFFESFSGLTTTGATTLVGL
CCCCCCCCCHHHHHHHHHHHHHHCCCCHHHCCCCCCCHHHHHHHHHCCCCCCCCHHHHHH
DSLPKAILFYRQMLQWMGGMGIIVLAVAILPILGVGGMQLYRAEMPGPLKDNKMRPRIAE
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCHHHH
TAKTLWLIYVLLTIACALALWGAGMSVFDAIGHSFSTIAIGGFSTHDASIGYYASPTINT
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCEEEECCCCCCCCCCCEECCCHHHH
IIAIFLLISGCNYGLHFALLSGRSLKVYWRDPEFRMFIAVQLTLVVVCTAVLWGHGVYKT
HHHHHHHHHCCCCCEEEEEECCCEEEEEEECCCEEEHHHHHHHHHHHHHHHHHCCCHHHH
GMETVNQAFFQVVSMATTAGFTTDSIAKWPLFLPMLLLCSAFIGGCAGSTGGGLKVIRIL
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
LLYLQGSRELKRLVHPNAVYTIKLGNRALPERILEAVWGFFSAYALVFIVSMLAIIATGV
HHHHCCCHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DDFSAFAAVTATLNNLGPGLGVVADNFTTMPAPAKWILVLTMLFGRLEVFTLLVLFTPTF
CHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHH
WRE
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Periplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Periplasm] = Proton [Cytoplasm] + K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]