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The map label for this gene is ftsY [H]

Identifier: 157368470

GI number: 157368470

Start: 248556

End: 250163

Strand: Direct

Name: ftsY [H]

Synonym: Spro_0221

Alternate gene names: 157368470

Gene position: 248556-250163 (Clockwise)

Preceding gene: 157368460

Following gene: 157368471

Centisome position: 4.56

GC content: 57.21

Gene sequence:

>1608_bases
ATGGCAAAAGATAAGAAACGCGGGTTTTTCTCCTGGCTGGGCTTCGGCCAGAAGGAAGAAGAGCAACAGCAACCTGAGAC
GGCGGTAGAACCGGCGGAAAATCAGGCCGTGGAGACCCCGGCTGAACCGGTTGCTCCCAAGCTGGATGACCAACTCCCCG
CCCAGGAATCTGAACCTGCCGCCTCCGTAGAAACCCCAGGAGAATGGGACGGCAGCCTGACCGGCGAGCATATCGCAGAA
AGCGTGCCAGTGGTTGCCGAGCACTCTGCAGCGGCACAAGCGCTGGCGGAAGAGATTGTTACCCTCACCGAACAGGTGGC
GGCAGAGCAGCAGCCGGTGACAGAGGAAGATATTGCCGAGCCGGTTGCCGAGGTTGAGCCTGAGCCGGTGGTGGTGATTG
AGCCGGAAGCGGTTGTCATACCTGAACCAGAATGGGTTGAGCCTGAGCCGGTTATCGAACCCGAGCCGGAAGTGATTGCG
CCTGAGCCTGTTATCGAGCCTGAGCCAGAACCTGAGGTTATCGCGCCAGAGCCAGAGCCAGAGCCAGAACCAGAACCAGA
GCCAGAGCCAGAGCCTCTGCCGGCCAGCGTAGCGCTGGAACCGATTATCGTCGCTCCGGCCATTATTGAAGAACAACAAC
CTGAGCTGCTGGCCCCTGCGGTGACTCAGGAGCAGGAACGCCCGACCAAAGAAGGTTTCTTTGCCCGTCTGAAACGCAGC
CTGGTGAAAACCAAGCAGAATCTGGGCTCCGGTTTTATCGGCCTGTTCCGCGGCAAGAAAATCGACGACGATCTGTTTGA
AGAGCTGGAAGAGCAGCTGCTGATTGCCGATGTCGGCGTGGAAACCACGCGTAAAATCATTACCTCCCTGACCCAGCACG
CCAGCCGCAAGCAGTTGAAAGACGCCGAGGCGCTATACGGCAAGCTGAAGGAGGAAATGTCTGAAATTCTGGCTAAAGTT
GATCAGCCGCTGGATGTTGGCGGTAAAAACCCGTATGTCATTCTGATGGTTGGTGTGAACGGCGTGGGTAAAACCACCAC
CATCGGCAAGCTGGCCCGTCAGTTCCAGGCGGAAGGCAAATCGGTGATGTTGGCGGCGGGGGATACCTTCCGTGCCGCGG
CGGTGGAACAACTGCAGGTATGGGGCGAGCGTAACCGGATCCCGGTGATCGCGCAGCATACCGGTGCTGACTCCGCTTCG
GTGATTTTTGACGCGGTACAGGCCGCCAAGGCTCGTGGCATCGACGTACTGCTGGCCGATACCGCCGGACGTCTGCAGAA
TAAAGCGCACCTGATGGAAGAGCTGAAGAAAATCGTCCGCGTTATGAAAAAACTGGACGACCAGGCCCCCCATGAGGTTA
TGCTGATTCTTGATGCCAGCACCGGACAGAATGCTGTCAGCCAGGCGAAATTATTTAATGAAGCCGTAGGCTTAACCGGT
ATCACACTGACTAAACTGGACGGTACCGCCAAGGGCGGGGTGATCTTCGCCATTGCCGATCAGTTCGCTATCCCGATTCG
CTATATCGGCGTTGGGGAAGGCATCGAAGATTTGCGGCCGTTTAAGGCCGACGATTTTATTGAGGCACTTTTTGCCCGAG
AGGATTAA

Upstream 100 bases:

>100_bases
AAAGCATACCGGATGCGTGTTGCTGGGCGAGGGAAAGTGATAGACTCGGCGGAATAATTGTCAGCATAAGCAAGCCTTCG
GTACGGAGTAGAGTCATAAC

Downstream 100 bases:

>100_bases
TACGGATGATTCGCTTTGAACAGGTCAGTAAAGCTTATCTGGGCGGACGGCAGGCACTGCAGGGGGTAGATTTTCATCTG
CGCCCGGCAGAGATGGCGTT

Product: signal recognition particle-docking protein FtsY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 535; Mature: 534

Protein sequence:

>535_residues
MAKDKKRGFFSWLGFGQKEEEQQQPETAVEPAENQAVETPAEPVAPKLDDQLPAQESEPAASVETPGEWDGSLTGEHIAE
SVPVVAEHSAAAQALAEEIVTLTEQVAAEQQPVTEEDIAEPVAEVEPEPVVVIEPEAVVIPEPEWVEPEPVIEPEPEVIA
PEPVIEPEPEPEVIAPEPEPEPEPEPEPEPEPLPASVALEPIIVAPAIIEEQQPELLAPAVTQEQERPTKEGFFARLKRS
LVKTKQNLGSGFIGLFRGKKIDDDLFEELEEQLLIADVGVETTRKIITSLTQHASRKQLKDAEALYGKLKEEMSEILAKV
DQPLDVGGKNPYVILMVGVNGVGKTTTIGKLARQFQAEGKSVMLAAGDTFRAAAVEQLQVWGERNRIPVIAQHTGADSAS
VIFDAVQAAKARGIDVLLADTAGRLQNKAHLMEELKKIVRVMKKLDDQAPHEVMLILDASTGQNAVSQAKLFNEAVGLTG
ITLTKLDGTAKGGVIFAIADQFAIPIRYIGVGEGIEDLRPFKADDFIEALFARED

Sequences:

>Translated_535_residues
MAKDKKRGFFSWLGFGQKEEEQQQPETAVEPAENQAVETPAEPVAPKLDDQLPAQESEPAASVETPGEWDGSLTGEHIAE
SVPVVAEHSAAAQALAEEIVTLTEQVAAEQQPVTEEDIAEPVAEVEPEPVVVIEPEAVVIPEPEWVEPEPVIEPEPEVIA
PEPVIEPEPEPEVIAPEPEPEPEPEPEPEPEPLPASVALEPIIVAPAIIEEQQPELLAPAVTQEQERPTKEGFFARLKRS
LVKTKQNLGSGFIGLFRGKKIDDDLFEELEEQLLIADVGVETTRKIITSLTQHASRKQLKDAEALYGKLKEEMSEILAKV
DQPLDVGGKNPYVILMVGVNGVGKTTTIGKLARQFQAEGKSVMLAAGDTFRAAAVEQLQVWGERNRIPVIAQHTGADSAS
VIFDAVQAAKARGIDVLLADTAGRLQNKAHLMEELKKIVRVMKKLDDQAPHEVMLILDASTGQNAVSQAKLFNEAVGLTG
ITLTKLDGTAKGGVIFAIADQFAIPIRYIGVGEGIEDLRPFKADDFIEALFARED
>Mature_534_residues
AKDKKRGFFSWLGFGQKEEEQQQPETAVEPAENQAVETPAEPVAPKLDDQLPAQESEPAASVETPGEWDGSLTGEHIAES
VPVVAEHSAAAQALAEEIVTLTEQVAAEQQPVTEEDIAEPVAEVEPEPVVVIEPEAVVIPEPEWVEPEPVIEPEPEVIAP
EPVIEPEPEPEVIAPEPEPEPEPEPEPEPEPLPASVALEPIIVAPAIIEEQQPELLAPAVTQEQERPTKEGFFARLKRSL
VKTKQNLGSGFIGLFRGKKIDDDLFEELEEQLLIADVGVETTRKIITSLTQHASRKQLKDAEALYGKLKEEMSEILAKVD
QPLDVGGKNPYVILMVGVNGVGKTTTIGKLARQFQAEGKSVMLAAGDTFRAAAVEQLQVWGERNRIPVIAQHTGADSASV
IFDAVQAAKARGIDVLLADTAGRLQNKAHLMEELKKIVRVMKKLDDQAPHEVMLILDASTGQNAVSQAKLFNEAVGLTGI
TLTKLDGTAKGGVIFAIADQFAIPIRYIGVGEGIEDLRPFKADDFIEALFARED

Specific function: Functional homolog of SRP receptor. Probably involved in the reception and insertion of a subset of proteins at the cytoplasmic membrane. Binds to the ribosome in the presence of the SRP particle and a non-hydrolyzable GTP analog. This abolishes trigger f

COG id: COG0552

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI226371618, Length=203, Percent_Identity=35.9605911330049, Blast_Score=131, Evalue=2e-30,
Organism=Homo sapiens, GI4507215, Length=203, Percent_Identity=35.9605911330049, Blast_Score=130, Evalue=4e-30,
Organism=Homo sapiens, GI295424842, Length=331, Percent_Identity=29.0030211480363, Blast_Score=125, Evalue=7e-29,
Organism=Homo sapiens, GI23308697, Length=331, Percent_Identity=29.0030211480363, Blast_Score=125, Evalue=9e-29,
Organism=Homo sapiens, GI89061728, Length=147, Percent_Identity=31.2925170068027, Blast_Score=81, Evalue=2e-15,
Organism=Escherichia coli, GI1789874, Length=543, Percent_Identity=65.5616942909761, Blast_Score=591, Evalue=1e-170,
Organism=Escherichia coli, GI1788963, Length=311, Percent_Identity=32.7974276527331, Blast_Score=152, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI17539958, Length=203, Percent_Identity=33.0049261083744, Blast_Score=122, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI193206261, Length=297, Percent_Identity=31.986531986532, Blast_Score=122, Evalue=7e-28,
Organism=Saccharomyces cerevisiae, GI6325345, Length=203, Percent_Identity=37.4384236453202, Blast_Score=134, Evalue=4e-32,
Organism=Saccharomyces cerevisiae, GI6320498, Length=239, Percent_Identity=32.2175732217573, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI17647949, Length=284, Percent_Identity=30.9859154929577, Blast_Score=128, Evalue=9e-30,
Organism=Drosophila melanogaster, GI24641198, Length=335, Percent_Identity=28.3582089552239, Blast_Score=120, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004390
- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N [H]

EC number: NA

Molecular weight: Translated: 57992; Mature: 57861

Theoretical pI: Translated: 4.12; Mature: 4.12

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKDKKRGFFSWLGFGQKEEEQQQPETAVEPAENQAVETPAEPVAPKLDDQLPAQESEPA
CCCCCCCCHHHHHCCCCCHHHHHCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
ASVETPGEWDGSLTGEHIAESVPVVAEHSAAAQALAEEIVTLTEQVAAEQQPVTEEDIAE
CCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
PVAEVEPEPVVVIEPEAVVIPEPEWVEPEPVIEPEPEVIAPEPVIEPEPEPEVIAPEPEP
HHHHCCCCCEEEECCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCC
EPEPEPEPEPEPLPASVALEPIIVAPAIIEEQQPELLAPAVTQEQERPTKEGFFARLKRS
CCCCCCCCCCCCCCHHHCCCHHHHCHHHHCCCCCCHHCCHHHHHHCCCCHHHHHHHHHHH
LVKTKQNLGSGFIGLFRGKKIDDDLFEELEEQLLIADVGVETTRKIITSLTQHASRKQLK
HHHHHHHHCCCCEEHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
DAEALYGKLKEEMSEILAKVDQPLDVGGKNPYVILMVGVNGVGKTTTIGKLARQFQAEGK
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCC
SVMLAAGDTFRAAAVEQLQVWGERNRIPVIAQHTGADSASVIFDAVQAAKARGIDVLLAD
EEEEECCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCEEEEEC
TAGRLQNKAHLMEELKKIVRVMKKLDDQAPHEVMLILDASTGQNAVSQAKLFNEAVGLTG
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCC
ITLTKLDGTAKGGVIFAIADQFAIPIRYIGVGEGIEDLRPFKADDFIEALFARED
EEEEECCCCCCCCEEEEEECCCCCCEEEEECCCCHHHHCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
AKDKKRGFFSWLGFGQKEEEQQQPETAVEPAENQAVETPAEPVAPKLDDQLPAQESEPA
CCCCCCCHHHHHCCCCCHHHHHCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
ASVETPGEWDGSLTGEHIAESVPVVAEHSAAAQALAEEIVTLTEQVAAEQQPVTEEDIAE
CCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
PVAEVEPEPVVVIEPEAVVIPEPEWVEPEPVIEPEPEVIAPEPVIEPEPEPEVIAPEPEP
HHHHCCCCCEEEECCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCC
EPEPEPEPEPEPLPASVALEPIIVAPAIIEEQQPELLAPAVTQEQERPTKEGFFARLKRS
CCCCCCCCCCCCCCHHHCCCHHHHCHHHHCCCCCCHHCCHHHHHHCCCCHHHHHHHHHHH
LVKTKQNLGSGFIGLFRGKKIDDDLFEELEEQLLIADVGVETTRKIITSLTQHASRKQLK
HHHHHHHHCCCCEEHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
DAEALYGKLKEEMSEILAKVDQPLDVGGKNPYVILMVGVNGVGKTTTIGKLARQFQAEGK
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCC
SVMLAAGDTFRAAAVEQLQVWGERNRIPVIAQHTGADSASVIFDAVQAAKARGIDVLLAD
EEEEECCCCHHHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHHHHHCCCEEEEEC
TAGRLQNKAHLMEELKKIVRVMKKLDDQAPHEVMLILDASTGQNAVSQAKLFNEAVGLTG
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCC
ITLTKLDGTAKGGVIFAIADQFAIPIRYIGVGEGIEDLRPFKADDFIEALFARED
EEEEECCCCCCCCEEEEEECCCCCCEEEEECCCCHHHHCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3025556; 8041620; 9278503; 2161989; 8194520; 9002525 [H]