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The map label for this gene is gpmB [H]

Identifier: 157163843

GI number: 157163843

Start: 4635683

End: 4636330

Strand: Direct

Name: gpmB [H]

Synonym: EcHS_A4631

Alternate gene names: 157163843

Gene position: 4635683-4636330 (Clockwise)

Preceding gene: 157163841

Following gene: 157163845

Centisome position: 99.83

GC content: 56.02

Gene sequence:

>648_bases
ATGTTACAGGTATACCTAGTCCGCCACGGTGAAACGCAGTGGAACGCCGAGCGACGTATTCAGGGCCAGTCTGACAGCCC
GCTGACCGCCAAAGGTGAGCAACAGGCGATGCAGGTGGCAACCCGTGCCAAAGAGCTTGGCATTACGCATATTATCAGTA
GCGATTTAGGACGCACCCGGCGTACGGCGGAAATCATCGCCCAGGCCTGCGGCTGTGACATCATCTTTGATTCTCGCCTG
CGTGAATTAAACATGGGTGTGCTGGAAAAAAGACATATCGATTCTCTGACCGAAGAAGAAGAGAACTGGCGTCGGCAGCT
GGTCAATGGCACCGTTGACGGGCGTATTCCTGAAGGCGAGTCAATGCAGGAGCTCAGCGATCGCGTCAATGCGGCACTGG
AATCTTGCCGGGACTTACCGCAGGGAAGCCGACCGCTGCTGGTGAGCCATGGTATTGCACTGGGATGTCTGGTGAGTACG
ATTCTCGGATTACCAGCATGGGCAGAGCGCCGCTTACGTCTGCGTAACTGTTCTATTTCGCGCGTGGATTATCAGGAAAG
CCTGTGGCTGGCGTCTGGCTGGGTCGTTGAAACCGCAGGGGACATCTCGCATCTGGACGCCCCTGCATTAGATGAGCTGC
AGCGTTAA

Upstream 100 bases:

>100_bases
TGGCCTGAATTTTAGCGGGATTGGTGGTCGCACAGACAACTTGGTGCATAATCAGCATTACTCAGAAAATTAACGTTACA
GCAGTATACGGAAAAAAAGC

Downstream 100 bases:

>100_bases
CGGCGGATAGGAATCAGCAGTTCACAGCGCAGATTAATTGGGCGATCTCCCGCTTTGGCGTCTTCTGCCGGGTAGTATCG
CTCAATATCCTGACCTTTAC

Product: phosphoglycerate mutase

Products: NA

Alternate protein names: PGAM; Phosphoglyceromutase [H]

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MLQVYLVRHGETQWNAERRIQGQSDSPLTAKGEQQAMQVATRAKELGITHIISSDLGRTRRTAEIIAQACGCDIIFDSRL
RELNMGVLEKRHIDSLTEEEENWRRQLVNGTVDGRIPEGESMQELSDRVNAALESCRDLPQGSRPLLVSHGIALGCLVST
ILGLPAWAERRLRLRNCSISRVDYQESLWLASGWVVETAGDISHLDAPALDELQR

Sequences:

>Translated_215_residues
MLQVYLVRHGETQWNAERRIQGQSDSPLTAKGEQQAMQVATRAKELGITHIISSDLGRTRRTAEIIAQACGCDIIFDSRL
RELNMGVLEKRHIDSLTEEEENWRRQLVNGTVDGRIPEGESMQELSDRVNAALESCRDLPQGSRPLLVSHGIALGCLVST
ILGLPAWAERRLRLRNCSISRVDYQESLWLASGWVVETAGDISHLDAPALDELQR
>Mature_215_residues
MLQVYLVRHGETQWNAERRIQGQSDSPLTAKGEQQAMQVATRAKELGITHIISSDLGRTRRTAEIIAQACGCDIIFDSRL
RELNMGVLEKRHIDSLTEEEENWRRQLVNGTVDGRIPEGESMQELSDRVNAALESCRDLPQGSRPLLVSHGIALGCLVST
ILGLPAWAERRLRLRNCSISRVDYQESLWLASGWVVETAGDISHLDAPALDELQR

Specific function: Unknown

COG id: COG0406

COG function: function code G; Fructose-2,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. GpmB subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790856, Length=215, Percent_Identity=100, Blast_Score=434, Evalue=1e-123,
Organism=Escherichia coli, GI1786857, Length=187, Percent_Identity=26.7379679144385, Blast_Score=76, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6324857, Length=217, Percent_Identity=25.8064516129032, Blast_Score=65, Evalue=6e-12,
Organism=Drosophila melanogaster, GI28571815, Length=206, Percent_Identity=30.5825242718447, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI28571817, Length=206, Percent_Identity=30.5825242718447, Blast_Score=71, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24648979, Length=206, Percent_Identity=30.5825242718447, Blast_Score=71, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR023086 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 24066; Mature: 24066

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: PS00175 PG_MUTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQVYLVRHGETQWNAERRIQGQSDSPLTAKGEQQAMQVATRAKELGITHIISSDLGRTR
CEEEEEEECCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHH
RTAEIIAQACGCDIIFDSRLRELNMGVLEKRHIDSLTEEEENWRRQLVNGTVDGRIPEGE
HHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
SMQELSDRVNAALESCRDLPQGSRPLLVSHGIALGCLVSTILGLPAWAERRLRLRNCSIS
CHHHHHHHHHHHHHHHHCCCCCCCCEEHHCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCC
RVDYQESLWLASGWVVETAGDISHLDAPALDELQR
CCCHHHHHHHHCCEEEECCCCHHHCCCCCHHHHCC
>Mature Secondary Structure
MLQVYLVRHGETQWNAERRIQGQSDSPLTAKGEQQAMQVATRAKELGITHIISSDLGRTR
CEEEEEEECCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHH
RTAEIIAQACGCDIIFDSRLRELNMGVLEKRHIDSLTEEEENWRRQLVNGTVDGRIPEGE
HHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
SMQELSDRVNAALESCRDLPQGSRPLLVSHGIALGCLVSTILGLPAWAERRLRLRNCSIS
CHHHHHHHHHHHHHHHHCCCCCCCCEEHHCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCC
RVDYQESLWLASGWVVETAGDISHLDAPALDELQR
CCCHHHHHHHHCCEEEECCCCHHHCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA