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The map label for this gene is yjjL [H]

Identifier: 157163803

GI number: 157163803

Start: 4596673

End: 4598034

Strand: Reverse

Name: yjjL [H]

Synonym: EcHS_A4587

Alternate gene names: 157163803

Gene position: 4598034-4596673 (Counterclockwise)

Preceding gene: 157163804

Following gene: 157163800

Centisome position: 99.02

GC content: 51.91

Gene sequence:

>1362_bases
GTGGAAAAAGAAAATATCACCCTCGATCCGCGTTCTTCATTTACTCCATCTTCGTCGGCAGATATTCCCGTGCCACCAGA
TGGATTAGTTCAACGCAGTACCCGAATTAAACGCATTCAAACCACCGCCATGTTGTTATTATTTTTTGCGGCGGTAATCA
ATTATCTCGACCGCAGTTCGCTGTCGGTAGCAAATTTAACGATTCGTGAAGAATTGGGATTAAGTGCCACCGAAATCGGC
GCTTTGCTCTCCGTGTTTTCACTCGCTTACGGGATTGCGCAACTTCCTTGCGGCCCACTATTGGATCGTAAAGGCCCACG
CCTGATGCTGGGACTGGGGATGTTCTTCTGGTCACTGTTCCAGGCAATGTCTGGCATGGTGCACAACTTTACGCAGTTCG
TGTTGGTGCGTATCGGTATGGGGATTGGTGAAGCGCCGATGAACCCATGCGGTGTAAAAGTCATTAACGACTGGTTCAAC
ATCAAAGAGCGCGGACGCCCGATGGGCTTCTTCAACGCAGCTTCTACCATTGGCGTTGCCGTAAGCCCACCGATTCTGGC
GGCGATGATGCTGGTGATGGGCTGGCGCGGGATGTTTATTACCATTGGTGTACTGGGGATTTTTCTCGCCATCGGCTGGT
ATATGCTCTATCGCAACCGCGAGCACGTAGAACTGACTGCCGTTGAACAAGCTTATCTCAATGCAGGTAGCGTCAATGCC
CGCCGAGATCCGCTCAGTTTTGCCGAATGGCGCAGCCTGTTCCGTAACCGTACAATGTGGGGAATGATGCTCGGATTCAG
TGGCATCAACTACACTGCGTGGCTGTATCTGGCCTGGCTTCCTGGTTACCTGCAAACAGCCTATAACCTGGATTTAAAAA
GCACAGGGTTGATGGCGGCTATCCCTTTCCTGTTTGGGGCTGCCGGGATGCTGGTCAACGGTTACGTTACTGACTGGCTG
GTCAAAGGGGGAATGGCTCCGATTAAAAGCCGTAAGATCTGCATTATTGCCGGGATGTTCTGTTCTGCCGCCTTTACGCT
GATAGTACCACAAGCGACAACATCCATGACGGCGGTTCTGCTGATTGGCATGGCACTGTTCTGTATTCACTTTGCCGGAA
CATCCTGCTGGGGCTTGATCCACGTCGCAGTTGCTTCTCGCATGACTGCGTCGGTGGGCAGTATCCAGAACTTTGCCAGC
TTCATCTGCGCCTCTTTTGCGCCGATCATTACTGGTTTTATTGTTGATACCACCCACTCATTCCGTCTGGCACTAATCAT
CTGCGGTTGCGTCACCGCAGCGGGGGCACTGGCGTACATCTTCCTGGTTCGTCAGCCGATCAACGACCCACGTAAAGATT
AA

Upstream 100 bases:

>100_bases
AGCGGTAGTAAAGTCCTAAAACTTTAACCTGCCGTTAATGTCAACCTTGCGTAATTCACAATTACGTAAACAATTAAAAT
TATAAATACAGGAGTCCGGC

Downstream 100 bases:

>100_bases
TCTCCTTATGCCCGATAACATTTTGCTTATCGGGCATTTTCATGGCGATTAAAATGTTTCCCAGTTCTCCTCGCTATCTG
CCACGGCCATTTTACGCGGC

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 453; Mature: 453

Protein sequence:

>453_residues
MEKENITLDPRSSFTPSSSADIPVPPDGLVQRSTRIKRIQTTAMLLLFFAAVINYLDRSSLSVANLTIREELGLSATEIG
ALLSVFSLAYGIAQLPCGPLLDRKGPRLMLGLGMFFWSLFQAMSGMVHNFTQFVLVRIGMGIGEAPMNPCGVKVINDWFN
IKERGRPMGFFNAASTIGVAVSPPILAAMMLVMGWRGMFITIGVLGIFLAIGWYMLYRNREHVELTAVEQAYLNAGSVNA
RRDPLSFAEWRSLFRNRTMWGMMLGFSGINYTAWLYLAWLPGYLQTAYNLDLKSTGLMAAIPFLFGAAGMLVNGYVTDWL
VKGGMAPIKSRKICIIAGMFCSAAFTLIVPQATTSMTAVLLIGMALFCIHFAGTSCWGLIHVAVASRMTASVGSIQNFAS
FICASFAPIITGFIVDTTHSFRLALIICGCVTAAGALAYIFLVRQPINDPRKD

Sequences:

>Translated_453_residues
MEKENITLDPRSSFTPSSSADIPVPPDGLVQRSTRIKRIQTTAMLLLFFAAVINYLDRSSLSVANLTIREELGLSATEIG
ALLSVFSLAYGIAQLPCGPLLDRKGPRLMLGLGMFFWSLFQAMSGMVHNFTQFVLVRIGMGIGEAPMNPCGVKVINDWFN
IKERGRPMGFFNAASTIGVAVSPPILAAMMLVMGWRGMFITIGVLGIFLAIGWYMLYRNREHVELTAVEQAYLNAGSVNA
RRDPLSFAEWRSLFRNRTMWGMMLGFSGINYTAWLYLAWLPGYLQTAYNLDLKSTGLMAAIPFLFGAAGMLVNGYVTDWL
VKGGMAPIKSRKICIIAGMFCSAAFTLIVPQATTSMTAVLLIGMALFCIHFAGTSCWGLIHVAVASRMTASVGSIQNFAS
FICASFAPIITGFIVDTTHSFRLALIICGCVTAAGALAYIFLVRQPINDPRKD
>Mature_453_residues
MEKENITLDPRSSFTPSSSADIPVPPDGLVQRSTRIKRIQTTAMLLLFFAAVINYLDRSSLSVANLTIREELGLSATEIG
ALLSVFSLAYGIAQLPCGPLLDRKGPRLMLGLGMFFWSLFQAMSGMVHNFTQFVLVRIGMGIGEAPMNPCGVKVINDWFN
IKERGRPMGFFNAASTIGVAVSPPILAAMMLVMGWRGMFITIGVLGIFLAIGWYMLYRNREHVELTAVEQAYLNAGSVNA
RRDPLSFAEWRSLFRNRTMWGMMLGFSGINYTAWLYLAWLPGYLQTAYNLDLKSTGLMAAIPFLFGAAGMLVNGYVTDWL
VKGGMAPIKSRKICIIAGMFCSAAFTLIVPQATTSMTAVLLIGMALFCIHFAGTSCWGLIHVAVASRMTASVGSIQNFAS
FICASFAPIITGFIVDTTHSFRLALIICGCVTAAGALAYIFLVRQPINDPRKD

Specific function: Responsible for the transport of L-galactonate from the periplasm across the inner membrane (Probable). Is essential for growth on L-galactonate as the sole carbon source [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI9966811, Length=424, Percent_Identity=21.2264150943396, Blast_Score=83, Evalue=7e-16,
Organism=Homo sapiens, GI6912666, Length=390, Percent_Identity=20.5128205128205, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI9945322, Length=389, Percent_Identity=21.3367609254499, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI148743791, Length=374, Percent_Identity=21.3903743315508, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI154350196, Length=325, Percent_Identity=23.6923076923077, Blast_Score=76, Evalue=8e-14,
Organism=Homo sapiens, GI4885441, Length=383, Percent_Identity=20.3655352480418, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI21322234, Length=393, Percent_Identity=21.1195928753181, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI185136021, Length=419, Percent_Identity=24.8210023866348, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI148728191, Length=312, Percent_Identity=21.474358974359, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI2367379, Length=453, Percent_Identity=99.7792494481236, Blast_Score=921, Evalue=0.0,
Organism=Escherichia coli, GI1789515, Length=434, Percent_Identity=30.184331797235, Blast_Score=205, Evalue=6e-54,
Organism=Escherichia coli, GI87082320, Length=435, Percent_Identity=29.4252873563218, Blast_Score=188, Evalue=5e-49,
Organism=Escherichia coli, GI1789152, Length=419, Percent_Identity=28.8782816229117, Blast_Score=166, Evalue=4e-42,
Organism=Escherichia coli, GI2367193, Length=310, Percent_Identity=28.3870967741935, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI87082310, Length=453, Percent_Identity=22.075055187638, Blast_Score=85, Evalue=9e-18,
Organism=Escherichia coli, GI87082071, Length=293, Percent_Identity=22.1843003412969, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI25141316, Length=473, Percent_Identity=23.8900634249471, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI25141318, Length=410, Percent_Identity=23.4146341463415, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI25141341, Length=373, Percent_Identity=23.3243967828418, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI115533556, Length=416, Percent_Identity=22.3557692307692, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI115533554, Length=416, Percent_Identity=22.3557692307692, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI86561091, Length=391, Percent_Identity=23.5294117647059, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17554148, Length=310, Percent_Identity=24.5161290322581, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71997452, Length=404, Percent_Identity=21.039603960396, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17566884, Length=301, Percent_Identity=25.5813953488372, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17535049, Length=443, Percent_Identity=20.5417607223476, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI193205400, Length=392, Percent_Identity=22.9591836734694, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17560030, Length=370, Percent_Identity=22.4324324324324, Blast_Score=66, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17554962, Length=315, Percent_Identity=21.2698412698413, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24648416, Length=448, Percent_Identity=22.7678571428571, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI21356189, Length=448, Percent_Identity=22.7678571428571, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI24641682, Length=402, Percent_Identity=22.636815920398, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24639764, Length=429, Percent_Identity=21.6783216783217, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24654215, Length=373, Percent_Identity=24.3967828418231, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI19922400, Length=373, Percent_Identity=24.6648793565684, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24583789, Length=305, Percent_Identity=22.9508196721311, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI28573708, Length=467, Percent_Identity=20.9850107066381, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI28573707, Length=467, Percent_Identity=20.9850107066381, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24655271, Length=446, Percent_Identity=23.0941704035874, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI20130135, Length=446, Percent_Identity=23.0941704035874, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28573299, Length=414, Percent_Identity=23.6714975845411, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI45550460, Length=440, Percent_Identity=23.6363636363636, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24584153, Length=393, Percent_Identity=21.882951653944, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24658658, Length=449, Percent_Identity=22.0489977728285, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24655255, Length=405, Percent_Identity=23.4567901234568, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24654041, Length=387, Percent_Identity=22.9974160206718, Blast_Score=72, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24654037, Length=387, Percent_Identity=22.9974160206718, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI17864456, Length=332, Percent_Identity=23.4939759036145, Blast_Score=69, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24654039, Length=332, Percent_Identity=23.4939759036145, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI45550364, Length=295, Percent_Identity=23.0508474576271, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI20129235, Length=410, Percent_Identity=20.9756097560976, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI20130167, Length=311, Percent_Identity=20.2572347266881, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 49441; Mature: 49441

Theoretical pI: Translated: 9.39; Mature: 9.39

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
7.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
5.3 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKENITLDPRSSFTPSSSADIPVPPDGLVQRSTRIKRIQTTAMLLLFFAAVINYLDRSS
CCCCCCEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LSVANLTIREELGLSATEIGALLSVFSLAYGIAQLPCGPLLDRKGPRLMLGLGMFFWSLF
CCCEEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHH
QAMSGMVHNFTQFVLVRIGMGIGEAPMNPCGVKVINDWFNIKERGRPMGFFNAASTIGVA
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEHHHHHCCEE
VSPPILAAMMLVMGWRGMFITIGVLGIFLAIGWYMLYRNREHVELTAVEQAYLNAGSVNA
ECCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHCCCCCCC
RRDPLSFAEWRSLFRNRTMWGMMLGFSGINYTAWLYLAWLPGYLQTAYNLDLKSTGLMAA
CCCCCCHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
IPFLFGAAGMLVNGYVTDWLVKGGMAPIKSRKICIIAGMFCSAAFTLIVPQATTSMTAVL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECHHHHHHHHHEECCHHHHHHHHH
LIGMALFCIHFAGTSCWGLIHVAVASRMTASVGSIQNFASFICASFAPIITGFIVDTTHS
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
FRLALIICGCVTAAGALAYIFLVRQPINDPRKD
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MEKENITLDPRSSFTPSSSADIPVPPDGLVQRSTRIKRIQTTAMLLLFFAAVINYLDRSS
CCCCCCEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LSVANLTIREELGLSATEIGALLSVFSLAYGIAQLPCGPLLDRKGPRLMLGLGMFFWSLF
CCCEEEEEHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHH
QAMSGMVHNFTQFVLVRIGMGIGEAPMNPCGVKVINDWFNIKERGRPMGFFNAASTIGVA
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEHHHHHCCEE
VSPPILAAMMLVMGWRGMFITIGVLGIFLAIGWYMLYRNREHVELTAVEQAYLNAGSVNA
ECCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHCCCCCCC
RRDPLSFAEWRSLFRNRTMWGMMLGFSGINYTAWLYLAWLPGYLQTAYNLDLKSTGLMAA
CCCCCCHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
IPFLFGAAGMLVNGYVTDWLVKGGMAPIKSRKICIIAGMFCSAAFTLIVPQATTSMTAVL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECHHHHHHHHHEECCHHHHHHHHH
LIGMALFCIHFAGTSCWGLIHVAVASRMTASVGSIQNFASFICASFAPIITGFIVDTTHS
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
FRLALIICGCVTAAGALAYIFLVRQPINDPRKD
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]