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The map label for this gene is yjiR [H]

Identifier: 157163786

GI number: 157163786

Start: 4575180

End: 4576592

Strand: Reverse

Name: yjiR [H]

Synonym: EcHS_A4568

Alternate gene names: 157163786

Gene position: 4576592-4575180 (Counterclockwise)

Preceding gene: 157163788

Following gene: 157163785

Centisome position: 98.56

GC content: 54.71

Gene sequence:

>1413_bases
ATGACGCGTTATCAACATCTGGCGACTCTACTTGCCGAGCGGATTGAGCAAGGGCTGTATCGTCACGGGGAGAAATTGCC
GTCGGTGCGCAGCTTAAGTCAGGAGCACGGCGTCAGCATCAGCACCGTGCAACAGGCGTATCAGACGCTGGAAACGATGA
AGCTCATCACTCCGCAGCCGCGTTCGGGTTATTTTGTCGCACAACGTAAAGCCCAGCCGCCAGTGCCGCCGATGACGCGT
CCGGTGCAGCGCCCGGTGGAAATTACCCAGTGGGATCAGGTGCTGGATATGCTGGTGGCGCATAGCGACAGTTCCATTGT
TCCGTTAAGCAAAAGCACGCCGGATGTCGAAACGCCCAGCCTGAAACCGCTCTGGCGGGAGCTAAGCCGGGTGGTGCAGC
ATAATCTGCAAACCGTGCTCGGTTATGACTTGTTAGCCGGTCAGCGGGTATTGCGAGAGCAGATTGCCCGCCTGATGCTC
GACAGCGGCTCGGTGGTCACCGCCGATGACATCATCATCACCAGCGGCTGCCATAACTCGATGTCGCTGGCGTTAATGGC
GGTGTGTAAACCGGGCGATATTGTCGCGGTCGAATCCCCCTGTTATTACGGTTCAATGCAGATGCTGCGCGTCATGGGCG
TGAAAGTGATTGAAATCCCAACCGATCCAGAAACTGGCATCAGCGTTGAAGCACTGGAACTGGCGCTGGAACAGTGGCCG
ATTAAAGGCATCATTCTGGTGCCAAACTGTAATAATCCGCTGGGATTTATTATGCCGGACGCACGCAAACGGGCCGTTCT
CTCTCTCGCTCAGCGTCATGATATTGTGATTTTTGAAGATGATGTCTACGGCGAACTGGCAACGGAGTATCCGCGCCCGC
GGACCATCCATTCATGGGATATCGACGGGCGAGTGTTGTTGTGCAGCTCGTTCAGTAAAAGTATTGCACCTGGCCTGCGC
GTGGGCTGGGTCGCACCGGGGCGATATCACGATAAACTGCTGCATATGAAATATGCCACCAGCAGCTTTAATGTACCGTC
CACGCAAATGGCGGCGGCAACGTTTGTGCTGGAAGGTCACTATCATCGCCATATCAGGCGGATGCGGCAGAACTATCAGC
GCAATTTGGCGCTTTATACCTGCTGGATACGGGAATATTTTCCCTGCGAAATCTGTATTACGCGCCCGAAAGGCGGATTT
TTACTGTGGATAGAATTGCCTGAACAGGTCGATATGGTCTGCGTTGCGCGGCAGCTGTGCCGCATGAATATCCAGGTGGC
AGCAGGCTCGATTTTCTCGGCTTCCGGCAAATACCGTAATTGTCTACGCATCAACTGCGCTTTGCCGCTCAGCGAAACCT
ATCGCGAAGCACTAAAGCAAATTGGCGAGGCCGTGTATCGGGCAATGGAATAA

Upstream 100 bases:

>100_bases
TATTTAACATACAGACAGGTTAAAACAGCATCTGCATCCGGTTTTTTAGCCTCATCTGTACCGGTTTTTCTTTCTGTATG
GGCCAAATAAGGAATACAGC

Downstream 100 bases:

>100_bases
ATTCGAATTAGTGGCGAAGCACCTGATTTCCTCTCACGAATCGCCTGTAACTCGTTGTATCTTTGCAGGGTCATCGCCAC
GTTCCAGCATGGCTTAGGCA

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 470; Mature: 469

Protein sequence:

>470_residues
MTRYQHLATLLAERIEQGLYRHGEKLPSVRSLSQEHGVSISTVQQAYQTLETMKLITPQPRSGYFVAQRKAQPPVPPMTR
PVQRPVEITQWDQVLDMLVAHSDSSIVPLSKSTPDVETPSLKPLWRELSRVVQHNLQTVLGYDLLAGQRVLREQIARLML
DSGSVVTADDIIITSGCHNSMSLALMAVCKPGDIVAVESPCYYGSMQMLRVMGVKVIEIPTDPETGISVEALELALEQWP
IKGIILVPNCNNPLGFIMPDARKRAVLSLAQRHDIVIFEDDVYGELATEYPRPRTIHSWDIDGRVLLCSSFSKSIAPGLR
VGWVAPGRYHDKLLHMKYATSSFNVPSTQMAAATFVLEGHYHRHIRRMRQNYQRNLALYTCWIREYFPCEICITRPKGGF
LLWIELPEQVDMVCVARQLCRMNIQVAAGSIFSASGKYRNCLRINCALPLSETYREALKQIGEAVYRAME

Sequences:

>Translated_470_residues
MTRYQHLATLLAERIEQGLYRHGEKLPSVRSLSQEHGVSISTVQQAYQTLETMKLITPQPRSGYFVAQRKAQPPVPPMTR
PVQRPVEITQWDQVLDMLVAHSDSSIVPLSKSTPDVETPSLKPLWRELSRVVQHNLQTVLGYDLLAGQRVLREQIARLML
DSGSVVTADDIIITSGCHNSMSLALMAVCKPGDIVAVESPCYYGSMQMLRVMGVKVIEIPTDPETGISVEALELALEQWP
IKGIILVPNCNNPLGFIMPDARKRAVLSLAQRHDIVIFEDDVYGELATEYPRPRTIHSWDIDGRVLLCSSFSKSIAPGLR
VGWVAPGRYHDKLLHMKYATSSFNVPSTQMAAATFVLEGHYHRHIRRMRQNYQRNLALYTCWIREYFPCEICITRPKGGF
LLWIELPEQVDMVCVARQLCRMNIQVAAGSIFSASGKYRNCLRINCALPLSETYREALKQIGEAVYRAME
>Mature_469_residues
TRYQHLATLLAERIEQGLYRHGEKLPSVRSLSQEHGVSISTVQQAYQTLETMKLITPQPRSGYFVAQRKAQPPVPPMTRP
VQRPVEITQWDQVLDMLVAHSDSSIVPLSKSTPDVETPSLKPLWRELSRVVQHNLQTVLGYDLLAGQRVLREQIARLMLD
SGSVVTADDIIITSGCHNSMSLALMAVCKPGDIVAVESPCYYGSMQMLRVMGVKVIEIPTDPETGISVEALELALEQWPI
KGIILVPNCNNPLGFIMPDARKRAVLSLAQRHDIVIFEDDVYGELATEYPRPRTIHSWDIDGRVLLCSSFSKSIAPGLRV
GWVAPGRYHDKLLHMKYATSSFNVPSTQMAAATFVLEGHYHRHIRRMRQNYQRNLALYTCWIREYFPCEICITRPKGGFL
LWIELPEQVDMVCVARQLCRMNIQVAAGSIFSASGKYRNCLRINCALPLSETYREALKQIGEAVYRAME

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=284, Percent_Identity=29.2253521126761, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI33469970, Length=284, Percent_Identity=29.2253521126761, Blast_Score=111, Evalue=2e-24,
Organism=Homo sapiens, GI4507369, Length=187, Percent_Identity=26.2032085561497, Blast_Score=72, Evalue=1e-12,
Organism=Escherichia coli, GI1790797, Length=470, Percent_Identity=98.5106382978723, Blast_Score=958, Evalue=0.0,
Organism=Escherichia coli, GI1787710, Length=466, Percent_Identity=34.9785407725322, Blast_Score=298, Evalue=7e-82,
Organism=Saccharomyces cerevisiae, GI6321929, Length=371, Percent_Identity=26.1455525606469, Blast_Score=89, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6321236, Length=184, Percent_Identity=30.4347826086957, Blast_Score=87, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6321000, Length=356, Percent_Identity=24.7191011235955, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21356535, Length=333, Percent_Identity=24.6246246246246, Blast_Score=88, Evalue=1e-17,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 53046; Mature: 52915

Theoretical pI: Translated: 8.29; Mature: 8.29

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRYQHLATLLAERIEQGLYRHGEKLPSVRSLSQEHGVSISTVQQAYQTLETMKLITPQP
CCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCC
RSGYFVAQRKAQPPVPPMTRPVQRPVEITQWDQVLDMLVAHSDSSIVPLSKSTPDVETPS
CCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCC
LKPLWRELSRVVQHNLQTVLGYDLLAGQRVLREQIARLMLDSGSVVTADDIIITSGCHNS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCEEEECCCCCC
MSLALMAVCKPGDIVAVESPCYYGSMQMLRVMGVKVIEIPTDPETGISVEALELALEQWP
HHEEEEEEECCCCEEEECCCCCCCHHHHHHHHCCEEEEECCCCCCCCCHHHHHHHHHHCC
IKGIILVPNCNNPLGFIMPDARKRAVLSLAQRHDIVIFEDDVYGELATEYPRPRTIHSWD
CCEEEEEECCCCCCEEECCCHHHHHHHHHHHHCCEEEEECCCCHHHHHCCCCCCCEEEEC
IDGRVLLCSSFSKSIAPGLRVGWVAPGRYHDKLLHMKYATSSFNVPSTQMAAATFVLEGH
CCCCEEEEECCHHHCCCCCEEEEECCCCHHHHHEEEEEECCCCCCCCHHHHHHHHEECCH
YHRHIRRMRQNYQRNLALYTCWIREYFPCEICITRPKGGFLLWIELPEQVDMVCVARQLC
HHHHHHHHHHHHHCCEEEEEEEHHHCCCCEEEEECCCCCEEEEEECCCHHHHHHHHHHHH
RMNIQVAAGSIFSASGKYRNCLRINCALPLSETYREALKQIGEAVYRAME
HCCEEEEECCEEECCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TRYQHLATLLAERIEQGLYRHGEKLPSVRSLSQEHGVSISTVQQAYQTLETMKLITPQP
CHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCC
RSGYFVAQRKAQPPVPPMTRPVQRPVEITQWDQVLDMLVAHSDSSIVPLSKSTPDVETPS
CCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCC
LKPLWRELSRVVQHNLQTVLGYDLLAGQRVLREQIARLMLDSGSVVTADDIIITSGCHNS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCEEEECCCCCC
MSLALMAVCKPGDIVAVESPCYYGSMQMLRVMGVKVIEIPTDPETGISVEALELALEQWP
HHEEEEEEECCCCEEEECCCCCCCHHHHHHHHCCEEEEECCCCCCCCCHHHHHHHHHHCC
IKGIILVPNCNNPLGFIMPDARKRAVLSLAQRHDIVIFEDDVYGELATEYPRPRTIHSWD
CCEEEEEECCCCCCEEECCCHHHHHHHHHHHHCCEEEEECCCCHHHHHCCCCCCCEEEEC
IDGRVLLCSSFSKSIAPGLRVGWVAPGRYHDKLLHMKYATSSFNVPSTQMAAATFVLEGH
CCCCEEEEECCHHHCCCCCEEEEECCCCHHHHHEEEEEECCCCCCCCHHHHHHHHEECCH
YHRHIRRMRQNYQRNLALYTCWIREYFPCEICITRPKGGFLLWIELPEQVDMVCVARQLC
HHHHHHHHHHHHHCCEEEEEEEHHHCCCCEEEEECCCCCEEEEEECCCHHHHHHHHHHHH
RMNIQVAAGSIFSASGKYRNCLRINCALPLSETYREALKQIGEAVYRAME
HCCEEEEECCEEECCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]