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The map label for this gene is fxsA

Identifier: 157163605

GI number: 157163605

Start: 4392687

End: 4393163

Strand: Direct

Name: fxsA

Synonym: EcHS_A4381

Alternate gene names: 157163605

Gene position: 4392687-4393163 (Clockwise)

Preceding gene: 157163594

Following gene: 157163607

Centisome position: 94.6

GC content: 47.8

Gene sequence:

>477_bases
TTGCGCTGGTTACCTTTTATTGCCATTTTCCTTTATGTCTATATTGAGATTTCAATCTTTATTCAGGTTGCCCATGTATT
GGGGGTATTGCTGACCCTCGTGCTGGTTATATTCACGTCAGTTATCGGGATGTCACTGGTACGTAACCAGGGCTTTAAGA
ATTTCGTGCTGATGCAGCAAAAAATGGCGGCGGGTGAAAACCCAGCGGCGGAGATGATTAAAAGTGTTTCGCTGATCATT
GCCGGTTTGCTGCTTTTATTACCGGGCTTTTTCACCGACTTCCTCGGTCTTCTGCTTTTATTACCGCCGGTGCAAAAGCA
TCTGACAGTGAAGTTGATGCCGCATTTGCGCTTTTCTCGTATGCCAGGCGGCGGTTTTAGCGCCGGGACCGGTGGCGGTA
ATACTTTTGATGGTGAGTACCAGCGAAAGGATGATGAGCGCGACCGCCTTGATCATAAAGACGATCGCCAGGATTAA

Upstream 100 bases:

>100_bases
ACATCTTGAAATTTTGCTAATGACCACAATATAAGCTGAACGCGATTCGCAACCCATTCAGGTAGCCGGGTTTTACCGGC
TGCTATTACAGGAGAAACCT

Downstream 100 bases:

>100_bases
TGTCGAAACGCCGGATTATGTGGTTATGCCATTTTCCGGCGTTTTTCGTTTTGGCAGCAACAGCCATAACCCCGCCAGCA
TGATCAGCGCATAGAGACTT

Product: FxsA

Products: NA

Alternate protein names: Suppressor of F exclusion of phage T7

Number of amino acids: Translated: 158; Mature: 158

Protein sequence:

>158_residues
MRWLPFIAIFLYVYIEISIFIQVAHVLGVLLTLVLVIFTSVIGMSLVRNQGFKNFVLMQQKMAAGENPAAEMIKSVSLII
AGLLLLLPGFFTDFLGLLLLLPPVQKHLTVKLMPHLRFSRMPGGGFSAGTGGGNTFDGEYQRKDDERDRLDHKDDRQD

Sequences:

>Translated_158_residues
MRWLPFIAIFLYVYIEISIFIQVAHVLGVLLTLVLVIFTSVIGMSLVRNQGFKNFVLMQQKMAAGENPAAEMIKSVSLII
AGLLLLLPGFFTDFLGLLLLLPPVQKHLTVKLMPHLRFSRMPGGGFSAGTGGGNTFDGEYQRKDDERDRLDHKDDRQD
>Mature_158_residues
MRWLPFIAIFLYVYIEISIFIQVAHVLGVLLTLVLVIFTSVIGMSLVRNQGFKNFVLMQQKMAAGENPAAEMIKSVSLII
AGLLLLLPGFFTDFLGLLLLLPPVQKHLTVKLMPHLRFSRMPGGGFSAGTGGGNTFDGEYQRKDDERDRLDHKDDRQD

Specific function: Overexpression alleviates the exclusion of phage T7 in cells harboring the F plasmid

COG id: COG3030

COG function: function code R; Protein affecting phage T7 exclusion by the F plasmid

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0716 (fxsA) family

Homologues:

Organism=Escherichia coli, GI87082376, Length=158, Percent_Identity=100, Blast_Score=318, Evalue=1e-88,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FXSA_ECOLI (P37147)

Other databases:

- EMBL:   U78484
- EMBL:   U14003
- EMBL:   U00096
- EMBL:   AP009048
- EMBL:   X04066
- PIR:   S56368
- RefSeq:   AP_004641.1
- RefSeq:   NP_418564.2
- ProteinModelPortal:   P37147
- STRING:   P37147
- EnsemblBacteria:   EBESCT00000001560
- EnsemblBacteria:   EBESCT00000017792
- GeneID:   948657
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW4100
- KEGG:   eco:b4140
- EchoBASE:   EB2284
- EcoGene:   EG12382
- eggNOG:   COG3030
- GeneTree:   EBGT00050000010053
- HOGENOM:   HBG687714
- OMA:   DKRPESH
- ProtClustDB:   PRK11463
- BioCyc:   EcoCyc:G7832-MONOMER
- Genevestigator:   P37147
- InterPro:   IPR007313

Pfam domain/function: PF04186 FxsA

EC number: NA

Molecular weight: Translated: 17692; Mature: 17692

Theoretical pI: Translated: 8.98; Mature: 8.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x189e26a4)-; HASH(0x405468e4)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRWLPFIAIFLYVYIEISIFIQVAHVLGVLLTLVLVIFTSVIGMSLVRNQGFKNFVLMQQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
KMAAGENPAAEMIKSVSLIIAGLLLLLPGFFTDFLGLLLLLPPVQKHLTVKLMPHLRFSR
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHC
MPGGGFSAGTGGGNTFDGEYQRKDDERDRLDHKDDRQD
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCH
>Mature Secondary Structure
MRWLPFIAIFLYVYIEISIFIQVAHVLGVLLTLVLVIFTSVIGMSLVRNQGFKNFVLMQQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
KMAAGENPAAEMIKSVSLIIAGLLLLLPGFFTDFLGLLLLLPPVQKHLTVKLMPHLRFSR
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHC
MPGGGFSAGTGGGNTFDGEYQRKDDERDRLDHKDDRQD
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10497016; 7610040; 9278503; 3541901; 7984428; 10497017