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The map label for this gene is ade [H]

Identifier: 157163147

GI number: 157163147

Start: 3873547

End: 3875313

Strand: Direct

Name: ade [H]

Synonym: EcHS_A3878

Alternate gene names: 157163147

Gene position: 3873547-3875313 (Clockwise)

Preceding gene: 157163143

Following gene: 157163155

Centisome position: 83.42

GC content: 54.84

Gene sequence:

>1767_bases
ATGAATAATTCTATTAACCATAAATTTCATCACATTAGCCGGGCTGAATACCAGGAATTGTTAGCCGTTTCCCGTGGCGA
CGCTGTTGCCGATTATCTTATTGATAATGTCTCTATTCTCGACCTGATCAATGGCGGAGAAATTTCCGGCCCAATTGTGA
TTAAAGGACGTTACATTGCCGGTGTTGGCGCAGAATACGCTGATGCTCCGGCTTTGCAGCGGATTGATGCTCGCGGCGCA
ACGGCGGTGCCAGGGTTTATTGATGCTCACCTGCATATTGAATCCAGCATGATGACGCCGGTCACTTTTGAAACCGCTAC
CCTGCCGCGCGGCCTGACGACCGTTATTTGCGACCCTCATGAAATCGTCAACGTGATGGGAGAAGCCGGATTCGCCTGGT
TTGCCCGCTGTGCCGAACAGGCAAGGCAAAACCAGTACTTACAGGTCAGCTCTTGCGTACCCGCCCTGGAAGGCTGCGAT
GTTAACGGTGCCAGTTTTACCCTTGAACAGATGCTCGCCTGGCGGGACCATCCGCAGGTTACCGGCCTTGCAGAAATGAT
GGACTACCCTGGCGTAATTAGCGGGCAGAATGCGCTGCTCGATAAACTGGATGCATTTCGCCACCTGACGCTGGACGGTC
ACTGCCCGGGTTTGGGTGGTAAAGAACTTAACGCCTATATTACTGCGGGTATTGAAAACTGCCACGAAAGTTATCAGCTG
GAAGAAGGACGCCGGAAATTACAACTCGGCATGTCGTTGATGATCCGCGAAGGGTCCGCTGCCCGCAATCTCAACGCGCT
GGCACCGTTGATCAACGAATTTAACAGCCCGCAATGCATGCTCTGTACCGATGACCGTAACCCGTGGGAGATCGCCCATG
AAGGACACATCGATGCCTTAATTCGCCGCCTGATCGAACAACACAATGTGCCGCTGCATGTGGCATATCGCGTCGCCAGC
TGGTCGACGGCGCGCCACTTTGGTCTGAATCACCTCGGCTTACTGGCACCCGGCAAGCAGGCCGATATCGTCCTGTTGAG
CGATGCGCGTAAGGTCACGGTGCAGCAGGTACTGGTGAAAGGCGAGCCGATTGATGCGCAAACCTTACAGGCGGAAGAGT
CGGCGAGACTGGCACAATCCGCTCCGCCATATGGCAACACCATTGCCCGCCAGCCAGTTTCCGCCAGCGACTTTGCCCTG
CAATTTACGCCCGGAAAACGCTATCGGGTCATTGACGTCATCCATAACGAATTGATTACGCACTCCCACTCCAGCGTCTA
CAGCGAAAATGGTTTTGATCGCGATGATGTGAGCTTTATTGCCGTACTTGAGCGTTACGGGCAACGGCTGGCTCCGGCTT
GTGGTTTGCTTGGCGGCTTTGGACTGAATGAAGGTGCGCTGGCTGCGACGGTCAGCCATGACAGCCATAATATTGTGGTG
ATCGGTCGCAGTGCCGAAGAGATGGCGCTGGCGGTCAATCAGGTGATTCAGGATGGCGGCGGGCTGTGCGTGGTACGTAA
CGGCCAGGTCCAAAGTCATCTGCCGTTGCCCATTGCCGGCCTGATGAGCACCGACACGGCGCAGTCGCTGGCGGAACAGA
TTGACGCCTTGAAAGCCGCCGCCCGTGAATGCGGTCCGTTACCCGATGAGCCGTTTATTCAGATGGCGTTTCTTTCTCTG
CCAGTGATCCCCGCGCTAAAACTAACCAGTCAGGGGCTATTTGATGGCGAGAAGTTTGCCTTCACTACGCTGGAAGTCAC
GGAATAA

Upstream 100 bases:

>100_bases
TCACATTTCAATTGCACATTAATGGATATTCTTTAATAATCTCGCGACGTTTCTTTATGATAAATAATAATCAAATTGAT
AAAATCAAAATGAGAAAAAT

Downstream 100 bases:

>100_bases
TAAAAAAGCCCGGCGTCATGCCGGGCAAAAGTCACCAGTTACGTTTATGCCACTGTCAACTGCTGAATTTTTTTCTCGCG
GCGGATTTTGCGTTCTTCCA

Product: cryptic adenine deaminase

Products: NA

Alternate protein names: Adenase; Adenine aminase [H]

Number of amino acids: Translated: 588; Mature: 588

Protein sequence:

>588_residues
MNNSINHKFHHISRAEYQELLAVSRGDAVADYLIDNVSILDLINGGEISGPIVIKGRYIAGVGAEYADAPALQRIDARGA
TAVPGFIDAHLHIESSMMTPVTFETATLPRGLTTVICDPHEIVNVMGEAGFAWFARCAEQARQNQYLQVSSCVPALEGCD
VNGASFTLEQMLAWRDHPQVTGLAEMMDYPGVISGQNALLDKLDAFRHLTLDGHCPGLGGKELNAYITAGIENCHESYQL
EEGRRKLQLGMSLMIREGSAARNLNALAPLINEFNSPQCMLCTDDRNPWEIAHEGHIDALIRRLIEQHNVPLHVAYRVAS
WSTARHFGLNHLGLLAPGKQADIVLLSDARKVTVQQVLVKGEPIDAQTLQAEESARLAQSAPPYGNTIARQPVSASDFAL
QFTPGKRYRVIDVIHNELITHSHSSVYSENGFDRDDVSFIAVLERYGQRLAPACGLLGGFGLNEGALAATVSHDSHNIVV
IGRSAEEMALAVNQVIQDGGGLCVVRNGQVQSHLPLPIAGLMSTDTAQSLAEQIDALKAAARECGPLPDEPFIQMAFLSL
PVIPALKLTSQGLFDGEKFAFTTLEVTE

Sequences:

>Translated_588_residues
MNNSINHKFHHISRAEYQELLAVSRGDAVADYLIDNVSILDLINGGEISGPIVIKGRYIAGVGAEYADAPALQRIDARGA
TAVPGFIDAHLHIESSMMTPVTFETATLPRGLTTVICDPHEIVNVMGEAGFAWFARCAEQARQNQYLQVSSCVPALEGCD
VNGASFTLEQMLAWRDHPQVTGLAEMMDYPGVISGQNALLDKLDAFRHLTLDGHCPGLGGKELNAYITAGIENCHESYQL
EEGRRKLQLGMSLMIREGSAARNLNALAPLINEFNSPQCMLCTDDRNPWEIAHEGHIDALIRRLIEQHNVPLHVAYRVAS
WSTARHFGLNHLGLLAPGKQADIVLLSDARKVTVQQVLVKGEPIDAQTLQAEESARLAQSAPPYGNTIARQPVSASDFAL
QFTPGKRYRVIDVIHNELITHSHSSVYSENGFDRDDVSFIAVLERYGQRLAPACGLLGGFGLNEGALAATVSHDSHNIVV
IGRSAEEMALAVNQVIQDGGGLCVVRNGQVQSHLPLPIAGLMSTDTAQSLAEQIDALKAAARECGPLPDEPFIQMAFLSL
PVIPALKLTSQGLFDGEKFAFTTLEVTE
>Mature_588_residues
MNNSINHKFHHISRAEYQELLAVSRGDAVADYLIDNVSILDLINGGEISGPIVIKGRYIAGVGAEYADAPALQRIDARGA
TAVPGFIDAHLHIESSMMTPVTFETATLPRGLTTVICDPHEIVNVMGEAGFAWFARCAEQARQNQYLQVSSCVPALEGCD
VNGASFTLEQMLAWRDHPQVTGLAEMMDYPGVISGQNALLDKLDAFRHLTLDGHCPGLGGKELNAYITAGIENCHESYQL
EEGRRKLQLGMSLMIREGSAARNLNALAPLINEFNSPQCMLCTDDRNPWEIAHEGHIDALIRRLIEQHNVPLHVAYRVAS
WSTARHFGLNHLGLLAPGKQADIVLLSDARKVTVQQVLVKGEPIDAQTLQAEESARLAQSAPPYGNTIARQPVSASDFAL
QFTPGKRYRVIDVIHNELITHSHSSVYSENGFDRDDVSFIAVLERYGQRLAPACGLLGGFGLNEGALAATVSHDSHNIVV
IGRSAEEMALAVNQVIQDGGGLCVVRNGQVQSHLPLPIAGLMSTDTAQSLAEQIDALKAAARECGPLPDEPFIQMAFLSL
PVIPALKLTSQGLFDGEKFAFTTLEVTE

Specific function: Unknown

COG id: COG1001

COG function: function code F; Adenine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenine deaminase family [H]

Homologues:

Organism=Escherichia coli, GI1790098, Length=588, Percent_Identity=99.6598639455782, Blast_Score=1209, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006679
- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.4.2 [H]

Molecular weight: Translated: 63710; Mature: 63710

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNSINHKFHHISRAEYQELLAVSRGDAVADYLIDNVSILDLINGGEISGPIVIKGRYIA
CCCCCCCHHHHCCHHHHHHHHHHCCCCHHHHHHHCCCEEEEEECCCCCCCCEEEEEEEEE
GVGAEYADAPALQRIDARGATAVPGFIDAHLHIESSMMTPVTFETATLPRGLTTVICDPH
ECCCCCCCCHHHHHHCCCCCCCCCCEEEEEEEEECCCCCCEEEECCCCCCCCEEEEECHH
EIVNVMGEAGFAWFARCAEQARQNQYLQVSSCVPALEGCDVNGASFTLEQMLAWRDHPQV
HHHHHHHCCCHHHHHHHHHHHHCCCCEEEHHCCCHHCCCCCCCCHHHHHHHHHHCCCCCH
TGLAEMMDYPGVISGQNALLDKLDAFRHLTLDGHCPGLGGKELNAYITAGIENCHESYQL
HHHHHHHCCCCEECCCHHHHHHHHHHHEEEECCCCCCCCCCCEEEEEEECHHHHHHHHHH
EEGRRKLQLGMSLMIREGSAARNLNALAPLINEFNSPQCMLCTDDRNPWEIAHEGHIDAL
HHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCEECCCCCHHHH
IRRLIEQHNVPLHVAYRVASWSTARHFGLNHLGLLAPGKQADIVLLSDARKVTVQQVLVK
HHHHHHHCCCCEEEEEEEECCCHHHHCCCCCCEEECCCCCCCEEEECCCCHHHHHHHHHC
GEPIDAQTLQAEESARLAQSAPPYGNTIARQPVSASDFALQFTPGKRYRVIDVIHNELIT
CCCCCHHHHCCHHHHHHHHCCCCCCCCHHCCCCCCCCEEEEECCCCCEEEHHHHHHHHHH
HSHSSVYSENGFDRDDVSFIAVLERYGQRLAPACGLLGGFGLNEGALAATVSHDSHNIVV
CCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEEE
IGRSAEEMALAVNQVIQDGGGLCVVRNGQVQSHLPLPIAGLMSTDTAQSLAEQIDALKAA
EECCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHH
ARECGPLPDEPFIQMAFLSLPVIPALKLTSQGLFDGEKFAFTTLEVTE
HHHCCCCCCCHHHHHHHHHCCCCHHHHHCCCCCCCCCEEEEEEEEECC
>Mature Secondary Structure
MNNSINHKFHHISRAEYQELLAVSRGDAVADYLIDNVSILDLINGGEISGPIVIKGRYIA
CCCCCCCHHHHCCHHHHHHHHHHCCCCHHHHHHHCCCEEEEEECCCCCCCCEEEEEEEEE
GVGAEYADAPALQRIDARGATAVPGFIDAHLHIESSMMTPVTFETATLPRGLTTVICDPH
ECCCCCCCCHHHHHHCCCCCCCCCCEEEEEEEEECCCCCCEEEECCCCCCCCEEEEECHH
EIVNVMGEAGFAWFARCAEQARQNQYLQVSSCVPALEGCDVNGASFTLEQMLAWRDHPQV
HHHHHHHCCCHHHHHHHHHHHHCCCCEEEHHCCCHHCCCCCCCCHHHHHHHHHHCCCCCH
TGLAEMMDYPGVISGQNALLDKLDAFRHLTLDGHCPGLGGKELNAYITAGIENCHESYQL
HHHHHHHCCCCEECCCHHHHHHHHHHHEEEECCCCCCCCCCCEEEEEEECHHHHHHHHHH
EEGRRKLQLGMSLMIREGSAARNLNALAPLINEFNSPQCMLCTDDRNPWEIAHEGHIDAL
HHHHHHHHHCCEEEEECCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCEECCCCCHHHH
IRRLIEQHNVPLHVAYRVASWSTARHFGLNHLGLLAPGKQADIVLLSDARKVTVQQVLVK
HHHHHHHCCCCEEEEEEEECCCHHHHCCCCCCEEECCCCCCCEEEECCCCHHHHHHHHHC
GEPIDAQTLQAEESARLAQSAPPYGNTIARQPVSASDFALQFTPGKRYRVIDVIHNELIT
CCCCCHHHHCCHHHHHHHHCCCCCCCCHHCCCCCCCCEEEEECCCCCEEEHHHHHHHHHH
HSHSSVYSENGFDRDDVSFIAVLERYGQRLAPACGLLGGFGLNEGALAATVSHDSHNIVV
CCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEEE
IGRSAEEMALAVNQVIQDGGGLCVVRNGQVQSHLPLPIAGLMSTDTAQSLAEQIDALKAA
EECCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHH
ARECGPLPDEPFIQMAFLSLPVIPALKLTSQGLFDGEKFAFTTLEVTE
HHHCCCCCCCHHHHHHHHHCCCCHHHHHCCCCCCCCCEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA