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The map label for this gene is yhjV

Identifier: 157163013

GI number: 157163013

Start: 3730034

End: 3731305

Strand: Direct

Name: yhjV

Synonym: EcHS_A3738

Alternate gene names: 157163013

Gene position: 3730034-3731305 (Clockwise)

Preceding gene: 157163010

Following gene: 157163020

Centisome position: 80.33

GC content: 45.44

Gene sequence:

>1272_bases
ATGCAGCACAACACACTATCGAAACACAATCAGAAATTGCCGTTTACACGCTACGACTTCGGCTGGGTTTTATTATGCAT
AGGCATGGCGATTGGTGCCGGAACCGTGCTGATGCCAGTACAAATTGGCTTGAAGGGAATTTGGGTATTTATTACCGCAG
CGATCATTGCTTATCCTGCCACCTGGGTAGTGCAGGACATTTATTTAAAAACCCTTTCTGAAAGCGATTCCTGTAATGAC
TACACCGATATTATCAGTCATTACCTGGGGAAGAACTGGGGAATTTTCCTCGGGGTTATCTACTTTTTGATGATTATCCA
CGGGATTTTTATCTACTCTCTCTCCGTGGTTTTCGACAGCGCCTCGTACCTGAAAACCTTCGGTTTAACCGATGCCGATC
TTTCACAATCTCTACTTTATAAAGTCGCTATTTTCGCCGTACTGGTGGCGATTGCGTCTGGTGGTGAACGATTACTGTTT
AAGATTTCCGGGCCAATGGTGGTGGTCAAAGTAGGGATTATTGTCGTGTTCGGTTTTGCGATGATCCCGCACTGGAATTT
CGCCAATATAACCGCCTTCCCGCAAGCCTCCGTCTTTTTCCGCGATGTCTTGCTTACCATTCCATTTTGCTTCTTTTCTG
CAGTATTTATTCAGGTACTTAACCCAATGAATATTGCCTATCGTAAACGGGAAGCGGATAAAGTACTGGCAACCCGGCTC
GCGCTGCGTACCCACCGAATTAGTTATATCACGCTCATCGCGGTGATCCTGTTTTTTGCCTTTTCGTTTACCTTCTCAAT
TAGCCACGAAGAAGCCGTTTCTGCCTTTGAACAAAATATCTCAGCACTGGCGCTGGCCGCGCAGGTGATCCCTGGGCATA
TCATTCATATCACCTCTACGGTGCTTAATATCTTTGCCGTACTGACCGCATTCTTTGGCATTTATCTCGGTTTCCACGAG
GCCATTAAAGGCATTATTCTCAATCTGTTAAGCCGAATTATTGATACCAAGAAAATTAACTCACGCGTGCTGACTCTGGC
GATCTGCGCTTTTATCGTCATTACGTTGACGATTTGGGTTTCGTTTCGTGTATCGGTGCTGGTGTTCTTTCAGTTGGGAA
GCCCGTTATATGGTATTGTGTCGTGCCTCATTCCGTTTTTCCTGATCTATAAAGTCGCACAACTGGAAAAACTTCGCGGA
TTTAAAGCCTGGCTGATTCTGCTGTACGGCATTTTGCTATGCTTGTCGCCACTGTTGAAGCTGATTGAGTAA

Upstream 100 bases:

>100_bases
CATTTTTTACATACTGCGTATTCGACTTCTCCACCTGTTGCGCAAGAGAAACTGGGTTTATTCATTTTTGCGAGGCCGAC
TTCTTTCTGGACAGGACTTT

Downstream 100 bases:

>100_bases
ACCGGAGCGCATGGCCCCGGTTTTGTGAGTTAACGCTGCGGATTTTCATCCTGATCAACAGCAAAACAAGCTACCAGTTG
ACCGCCGTAGTCTTTTAGCT

Product: serine transporter family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 423; Mature: 423

Protein sequence:

>423_residues
MQHNTLSKHNQKLPFTRYDFGWVLLCIGMAIGAGTVLMPVQIGLKGIWVFITAAIIAYPATWVVQDIYLKTLSESDSCND
YTDIISHYLGKNWGIFLGVIYFLMIIHGIFIYSLSVVFDSASYLKTFGLTDADLSQSLLYKVAIFAVLVAIASGGERLLF
KISGPMVVVKVGIIVVFGFAMIPHWNFANITAFPQASVFFRDVLLTIPFCFFSAVFIQVLNPMNIAYRKREADKVLATRL
ALRTHRISYITLIAVILFFAFSFTFSISHEEAVSAFEQNISALALAAQVIPGHIIHITSTVLNIFAVLTAFFGIYLGFHE
AIKGIILNLLSRIIDTKKINSRVLTLAICAFIVITLTIWVSFRVSVLVFFQLGSPLYGIVSCLIPFFLIYKVAQLEKLRG
FKAWLILLYGILLCLSPLLKLIE

Sequences:

>Translated_423_residues
MQHNTLSKHNQKLPFTRYDFGWVLLCIGMAIGAGTVLMPVQIGLKGIWVFITAAIIAYPATWVVQDIYLKTLSESDSCND
YTDIISHYLGKNWGIFLGVIYFLMIIHGIFIYSLSVVFDSASYLKTFGLTDADLSQSLLYKVAIFAVLVAIASGGERLLF
KISGPMVVVKVGIIVVFGFAMIPHWNFANITAFPQASVFFRDVLLTIPFCFFSAVFIQVLNPMNIAYRKREADKVLATRL
ALRTHRISYITLIAVILFFAFSFTFSISHEEAVSAFEQNISALALAAQVIPGHIIHITSTVLNIFAVLTAFFGIYLGFHE
AIKGIILNLLSRIIDTKKINSRVLTLAICAFIVITLTIWVSFRVSVLVFFQLGSPLYGIVSCLIPFFLIYKVAQLEKLRG
FKAWLILLYGILLCLSPLLKLIE
>Mature_423_residues
MQHNTLSKHNQKLPFTRYDFGWVLLCIGMAIGAGTVLMPVQIGLKGIWVFITAAIIAYPATWVVQDIYLKTLSESDSCND
YTDIISHYLGKNWGIFLGVIYFLMIIHGIFIYSLSVVFDSASYLKTFGLTDADLSQSLLYKVAIFAVLVAIASGGERLLF
KISGPMVVVKVGIIVVFGFAMIPHWNFANITAFPQASVFFRDVLLTIPFCFFSAVFIQVLNPMNIAYRKREADKVLATRL
ALRTHRISYITLIAVILFFAFSFTFSISHEEAVSAFEQNISALALAAQVIPGHIIHITSTVLNIFAVLTAFFGIYLGFHE
AIKGIILNLLSRIIDTKKINSRVLTLAICAFIVITLTIWVSFRVSVLVFFQLGSPLYGIVSCLIPFFLIYKVAQLEKLRG
FKAWLILLYGILLCLSPLLKLIE

Specific function: Unknown

COG id: COG0814

COG function: function code E; Amino acid permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid/polyamine transporter 2 family. SdaC/TdcC subfamily

Homologues:

Organism=Escherichia coli, GI1789961, Length=423, Percent_Identity=100, Blast_Score=847, Evalue=0.0,
Organism=Escherichia coli, GI145693183, Length=416, Percent_Identity=45.1923076923077, Blast_Score=384, Evalue=1e-108,
Organism=Escherichia coli, GI1789160, Length=411, Percent_Identity=25.3041362530414, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1789504, Length=422, Percent_Identity=23.9336492890995, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1789211, Length=409, Percent_Identity=21.5158924205379, Blast_Score=81, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YHJV_ECOLI (P37660)

Other databases:

- EMBL:   U00039
- EMBL:   U00096
- EMBL:   AP009048
- PIR:   S47761
- RefSeq:   AP_004254.1
- RefSeq:   NP_417996.1
- ProteinModelPortal:   P37660
- STRING:   P37660
- EnsemblBacteria:   EBESCT00000000459
- EnsemblBacteria:   EBESCT00000014228
- GeneID:   948057
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW3508
- KEGG:   eco:b3539
- EchoBASE:   EB2175
- EcoGene:   EG12266
- eggNOG:   COG0814
- GeneTree:   EBGT00050000008986
- HOGENOM:   HBG297876
- OMA:   YSFLRGR
- ProtClustDB:   CLSK880592
- BioCyc:   EcoCyc:YHJV-MONOMER
- Genevestigator:   P37660
- InterPro:   IPR004694
- InterPro:   IPR018227
- TIGRFAMs:   TIGR00814

Pfam domain/function: PF03222 Trp_Tyr_perm

EC number: NA

Molecular weight: Translated: 47258; Mature: 47258

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: PS00307 LECTIN_LEGUME_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x15aad318)-; HASH(0x18505a18)-; HASH(0x180da2a4)-; HASH(0x1808770c)-; HASH(0x179b5668)-; HASH(0x1883a7f0)-; HASH(0x16724ac0)-; HASH(0x184f2f64)-; HASH(0x1703762c)-; HASH(0x181109e0)-; HASH(0x17613054)-;

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HCH
>Mature Secondary Structure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HCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503