| Definition | Escherichia coli HS, complete genome. |
|---|---|
| Accession | NC_009800 |
| Length | 4,643,538 |
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The map label for this gene is nikD [H]
Identifier: 157162956
GI number: 157162956
Start: 3663285
End: 3664049
Strand: Direct
Name: nikD [H]
Synonym: EcHS_A3678
Alternate gene names: 157162956
Gene position: 3663285-3664049 (Clockwise)
Preceding gene: 157162955
Following gene: 157162957
Centisome position: 78.89
GC content: 59.35
Gene sequence:
>765_bases ATGCCGCAACAGATTGAACTACGTAATATCGCGCTACAGGCCGCGCAGCCGCTGGTACACGGTGTATCGTTAACCCTGCA ACGCGGGCGCGTGCTGGCGTTAGTCGGCGGTAGCGGCAGCGGGAAATCATTAACCTGCGCCGTGGCGCTGGGAATTCTGC CCGCAGGCGTTCGCCAGACGGCGGGGGAAATTTTAGCCGATGGCAAACCGGTTTCGCCTTGCGCCCTGCGCGGCATCAAA ATTGCCACCATCATGCAGAACCCGCGCAGCGCCTTTAATCCACTGCACACCATGCACACCCACGCGCGGGAAACCTGCCT GGCGTTAGGGAAACCCGCCGATGACGCTACGCTTACCGCTGCCATAGAAGCGGTGGGGCTGGAAAACGCCGCGCGCGTGC TGAAGCTGTACCCGTTCGAGATGAGCGGCGGCATGTTGCAGCGCATGATGATTGCGATGGCGGTGCTGTGTGAATCACCG TTTATCATCGCCGATGAACCGACCACCGACCTCGACGTGGTAGCACAGGCGCGCATCCTCGATCTGCTGGAAAGCATTAT GCAAAAACAAGCGCCGGGAATGCTGCTGGTCACCCATGATATGGGCGTTGTGGCGCGTCTGGCGGATGACGTGGCGGTGA TGTCACAAGGTAAAATTGTCGAACAGGGCGATGTAGAAACGCTGTTTAACGCCCCCAAACATACGGTGACGCGCAGCCTG GTTTCCGCTCATCTCGCCCTCTACGGTATGGAGCTGGCATCATGA
Upstream 100 bases:
>100_bases CGGGGCTGGCGCTGTTTATCAGCGTGATGGCCTTTAACCTGGTGGGTGACGCACTGCGCGATCATCTGGACCCTCATCTG GTGACGGAGCACGCACACTA
Downstream 100 bases:
>100_bases CCTTACTTAACGTCTGCGGCCTTTCCCATCACTATGCCCACGGTGGATTTAGCGGAAAACATCAACATCAGGCGGTGCTG AATAACGTTTCCCTGACCCT
Product: nickel transporter ATP-binding protein NikD
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 254; Mature: 253
Protein sequence:
>254_residues MPQQIELRNIALQAAQPLVHGVSLTLQRGRVLALVGGSGSGKSLTCAVALGILPAGVRQTAGEILADGKPVSPCALRGIK IATIMQNPRSAFNPLHTMHTHARETCLALGKPADDATLTAAIEAVGLENAARVLKLYPFEMSGGMLQRMMIAMAVLCESP FIIADEPTTDLDVVAQARILDLLESIMQKQAPGMLLVTHDMGVVARLADDVAVMSQGKIVEQGDVETLFNAPKHTVTRSL VSAHLALYGMELAS
Sequences:
>Translated_254_residues MPQQIELRNIALQAAQPLVHGVSLTLQRGRVLALVGGSGSGKSLTCAVALGILPAGVRQTAGEILADGKPVSPCALRGIK IATIMQNPRSAFNPLHTMHTHARETCLALGKPADDATLTAAIEAVGLENAARVLKLYPFEMSGGMLQRMMIAMAVLCESP FIIADEPTTDLDVVAQARILDLLESIMQKQAPGMLLVTHDMGVVARLADDVAVMSQGKIVEQGDVETLFNAPKHTVTRSL VSAHLALYGMELAS >Mature_253_residues PQQIELRNIALQAAQPLVHGVSLTLQRGRVLALVGGSGSGKSLTCAVALGILPAGVRQTAGEILADGKPVSPCALRGIKI ATIMQNPRSAFNPLHTMHTHARETCLALGKPADDATLTAAIEAVGLENAARVLKLYPFEMSGGMLQRMMIAMAVLCESPF IIADEPTTDLDVVAQARILDLLESIMQKQAPGMLLVTHDMGVVARLADDVAVMSQGKIVEQGDVETLFNAPKHTVTRSLV SAHLALYGMELAS
Specific function: Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system [H]
COG id: COG0444
COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component
Gene ontology:
Cell location: Cell inner membrane; Peripheral membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 ABC transporter domain [H]
Homologues:
Organism=Homo sapiens, GI171184400, Length=262, Percent_Identity=29.0076335877863, Blast_Score=74, Evalue=2e-13, Organism=Homo sapiens, GI27436953, Length=212, Percent_Identity=25.9433962264151, Blast_Score=73, Evalue=2e-13, Organism=Homo sapiens, GI105990541, Length=211, Percent_Identity=25.1184834123223, Blast_Score=72, Evalue=7e-13, Organism=Homo sapiens, GI42490749, Length=230, Percent_Identity=27.8260869565217, Blast_Score=71, Evalue=8e-13, Organism=Homo sapiens, GI116734710, Length=202, Percent_Identity=25.7425742574257, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI21536376, Length=208, Percent_Identity=27.8846153846154, Blast_Score=69, Evalue=6e-12, Organism=Homo sapiens, GI153792144, Length=215, Percent_Identity=25.1162790697674, Blast_Score=68, Evalue=7e-12, Organism=Homo sapiens, GI6005701, Length=210, Percent_Identity=25.7142857142857, Blast_Score=64, Evalue=1e-10, Organism=Escherichia coli, GI1789890, Length=254, Percent_Identity=98.8188976377953, Blast_Score=506, Evalue=1e-145, Organism=Escherichia coli, GI1788506, Length=241, Percent_Identity=41.0788381742739, Blast_Score=161, Evalue=4e-41, Organism=Escherichia coli, GI145693107, Length=257, Percent_Identity=38.9105058365759, Blast_Score=159, Evalue=2e-40, Organism=Escherichia coli, GI1789963, Length=234, Percent_Identity=35.8974358974359, Blast_Score=147, Evalue=1e-36, Organism=Escherichia coli, GI1787759, Length=251, Percent_Identity=33.8645418326693, Blast_Score=140, Evalue=1e-34, Organism=Escherichia coli, GI48994883, Length=234, Percent_Identity=35.042735042735, Blast_Score=135, Evalue=3e-33, Organism=Escherichia coli, GI1789962, Length=232, Percent_Identity=35.3448275862069, Blast_Score=122, Evalue=2e-29, Organism=Escherichia coli, GI1787500, Length=232, Percent_Identity=32.3275862068966, Blast_Score=114, Evalue=6e-27, Organism=Escherichia coli, GI1787758, Length=227, Percent_Identity=31.2775330396476, Blast_Score=107, Evalue=1e-24, Organism=Escherichia coli, GI1787548, Length=241, Percent_Identity=28.6307053941909, Blast_Score=105, Evalue=4e-24, Organism=Escherichia coli, GI1787547, Length=246, Percent_Identity=28.0487804878049, Blast_Score=105, Evalue=4e-24, Organism=Escherichia coli, GI1789891, Length=211, Percent_Identity=36.4928909952607, Blast_Score=103, Evalue=8e-24, Organism=Escherichia coli, GI48994997, Length=230, Percent_Identity=32.1739130434783, Blast_Score=97, Evalue=8e-22, Organism=Escherichia coli, GI1788225, Length=256, Percent_Identity=31.25, Blast_Score=96, Evalue=2e-21, Organism=Escherichia coli, GI1786398, Length=235, Percent_Identity=30.2127659574468, Blast_Score=92, Evalue=2e-20, Organism=Escherichia coli, GI1789032, Length=230, Percent_Identity=29.1304347826087, Blast_Score=85, Evalue=4e-18, Organism=Escherichia coli, GI1786345, Length=224, Percent_Identity=31.25, Blast_Score=85, Evalue=5e-18, Organism=Escherichia coli, GI1787112, Length=228, Percent_Identity=28.5087719298246, Blast_Score=83, Evalue=2e-17, Organism=Escherichia coli, GI1790162, Length=257, Percent_Identity=25.6809338521401, Blast_Score=83, Evalue=2e-17, Organism=Escherichia coli, GI87081834, Length=216, Percent_Identity=31.4814814814815, Blast_Score=82, Evalue=4e-17, Organism=Escherichia coli, GI87081791, Length=235, Percent_Identity=29.7872340425532, Blast_Score=79, Evalue=2e-16, Organism=Escherichia coli, GI1787029, Length=239, Percent_Identity=27.1966527196653, Blast_Score=78, Evalue=7e-16, Organism=Escherichia coli, GI1788450, Length=247, Percent_Identity=29.1497975708502, Blast_Score=77, Evalue=9e-16, Organism=Escherichia coli, GI1789672, Length=246, Percent_Identity=28.8617886178862, Blast_Score=77, Evalue=1e-15, Organism=Escherichia coli, GI87081709, Length=230, Percent_Identity=25.2173913043478, Blast_Score=76, Evalue=2e-15, Organism=Escherichia coli, GI1788761, Length=229, Percent_Identity=31.0043668122271, Blast_Score=75, Evalue=3e-15, Organism=Escherichia coli, GI1787089, Length=244, Percent_Identity=29.5081967213115, Blast_Score=75, Evalue=4e-15, Organism=Escherichia coli, GI1789873, Length=208, Percent_Identity=29.3269230769231, Blast_Score=75, Evalue=5e-15, Organism=Escherichia coli, GI48994943, Length=229, Percent_Identity=26.2008733624454, Blast_Score=74, Evalue=8e-15, Organism=Escherichia coli, GI1790739, Length=220, Percent_Identity=27.2727272727273, Blast_Score=74, Evalue=1e-14, Organism=Escherichia coli, GI1787712, Length=254, Percent_Identity=27.9527559055118, Blast_Score=73, Evalue=1e-14, Organism=Escherichia coli, GI1786803, Length=229, Percent_Identity=27.5109170305677, Blast_Score=73, Evalue=2e-14, Organism=Escherichia coli, GI1786872, Length=216, Percent_Identity=32.8703703703704, Blast_Score=72, Evalue=4e-14, Organism=Escherichia coli, GI1787143, Length=226, Percent_Identity=26.9911504424779, Blast_Score=71, Evalue=5e-14, Organism=Escherichia coli, GI1786703, Length=212, Percent_Identity=29.7169811320755, Blast_Score=71, Evalue=6e-14, Organism=Escherichia coli, GI1787164, Length=192, Percent_Identity=31.25, Blast_Score=70, Evalue=1e-13, Organism=Escherichia coli, GI1786253, Length=216, Percent_Identity=27.7777777777778, Blast_Score=70, Evalue=2e-13, Organism=Escherichia coli, GI1787370, Length=215, Percent_Identity=25.5813953488372, Blast_Score=69, Evalue=2e-13, Organism=Escherichia coli, GI1789586, Length=246, Percent_Identity=27.2357723577236, Blast_Score=69, Evalue=2e-13, Organism=Escherichia coli, GI1788540, Length=227, Percent_Identity=29.9559471365639, Blast_Score=69, Evalue=4e-13, Organism=Escherichia coli, GI1788644, Length=128, Percent_Identity=32.03125, Blast_Score=67, Evalue=1e-12, Organism=Escherichia coli, GI1786654, Length=265, Percent_Identity=27.9245283018868, Blast_Score=65, Evalue=4e-12, Organism=Escherichia coli, GI1788165, Length=218, Percent_Identity=28.4403669724771, Blast_Score=65, Evalue=4e-12, Organism=Escherichia coli, GI1786319, Length=218, Percent_Identity=25.2293577981651, Blast_Score=65, Evalue=6e-12, Organism=Escherichia coli, GI1787792, Length=229, Percent_Identity=29.2576419213974, Blast_Score=63, Evalue=2e-11, Organism=Escherichia coli, GI1789991, Length=218, Percent_Identity=26.605504587156, Blast_Score=62, Evalue=3e-11, Organism=Escherichia coli, GI1787105, Length=210, Percent_Identity=30, Blast_Score=61, Evalue=8e-11, Organism=Caenorhabditis elegans, GI193208177, Length=253, Percent_Identity=25.6916996047431, Blast_Score=77, Evalue=8e-15, Organism=Caenorhabditis elegans, GI71983523, Length=221, Percent_Identity=30.7692307692308, Blast_Score=70, Evalue=7e-13, Organism=Caenorhabditis elegans, GI71983516, Length=221, Percent_Identity=30.7692307692308, Blast_Score=70, Evalue=7e-13, Organism=Caenorhabditis elegans, GI71983510, Length=221, Percent_Identity=30.7692307692308, Blast_Score=70, Evalue=7e-13, Organism=Caenorhabditis elegans, GI115535101, Length=227, Percent_Identity=27.7533039647577, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17510237, Length=220, Percent_Identity=29.0909090909091, Blast_Score=68, Evalue=4e-12, Organism=Caenorhabditis elegans, GI193211015, Length=231, Percent_Identity=27.2727272727273, Blast_Score=67, Evalue=6e-12, Organism=Caenorhabditis elegans, GI115533592, Length=241, Percent_Identity=27.3858921161826, Blast_Score=67, Evalue=7e-12, Organism=Caenorhabditis elegans, GI193211017, Length=231, Percent_Identity=27.2727272727273, Blast_Score=67, Evalue=8e-12, Organism=Caenorhabditis elegans, GI17565938, Length=221, Percent_Identity=27.6018099547511, Blast_Score=67, Evalue=8e-12, Organism=Caenorhabditis elegans, GI17567265, Length=225, Percent_Identity=27.1111111111111, Blast_Score=67, Evalue=9e-12, Organism=Caenorhabditis elegans, GI212646699, Length=227, Percent_Identity=26.8722466960352, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI71984940, Length=240, Percent_Identity=26.25, Blast_Score=66, Evalue=1e-11, Organism=Caenorhabditis elegans, GI193202349, Length=241, Percent_Identity=24.896265560166, Blast_Score=66, Evalue=1e-11, Organism=Caenorhabditis elegans, GI71996809, Length=231, Percent_Identity=27.2727272727273, Blast_Score=66, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17567269, Length=222, Percent_Identity=27.027027027027, Blast_Score=64, Evalue=6e-11, Organism=Saccharomyces cerevisiae, GI6322640, Length=223, Percent_Identity=27.3542600896861, Blast_Score=63, Evalue=4e-11, Organism=Drosophila melanogaster, GI116007184, Length=226, Percent_Identity=26.1061946902655, Blast_Score=68, Evalue=7e-12, Organism=Drosophila melanogaster, GI221500365, Length=226, Percent_Identity=26.1061946902655, Blast_Score=68, Evalue=7e-12, Organism=Drosophila melanogaster, GI23397593, Length=238, Percent_Identity=28.5714285714286, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI28574533, Length=242, Percent_Identity=26.4462809917355, Blast_Score=65, Evalue=3e-11, Organism=Drosophila melanogaster, GI24643674, Length=208, Percent_Identity=23.5576923076923, Blast_Score=65, Evalue=4e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003439 - InterPro: IPR017871 - InterPro: IPR015857 - InterPro: IPR003593 - InterPro: IPR014138 [H]
Pfam domain/function: PF00005 ABC_tran [H]
EC number: =3.6.3.24 [H]
Molecular weight: Translated: 26832; Mature: 26701
Theoretical pI: Translated: 6.62; Mature: 6.62
Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.6 %Cys (Translated Protein) 5.1 %Met (Translated Protein) 6.7 %Cys+Met (Translated Protein) 1.6 %Cys (Mature Protein) 4.7 %Met (Mature Protein) 6.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MPQQIELRNIALQAAQPLVHGVSLTLQRGRVLALVGGSGSGKSLTCAVALGILPAGVRQT CCCCCHHHHHHHHHHHHHHHHHHEEEECCEEEEEECCCCCCCEEEEEHHHHHCCCCHHHH AGEILADGKPVSPCALRGIKIATIMQNPRSAFNPLHTMHTHARETCLALGKPADDATLTA HHHHHCCCCCCCHHHHCCEEEEEECCCCHHHHCHHHHHHHHHHHHHHHCCCCCCCHHHHH AIEAVGLENAARVLKLYPFEMSGGMLQRMMIAMAVLCESPFIIADEPTTDLDVVAQARIL HHHHHCHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHH DLLESIMQKQAPGMLLVTHDMGVVARLADDVAVMSQGKIVEQGDVETLFNAPKHTVTRSL HHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHCCCCEECCCCHHHHHCCCHHHHHHHH VSAHLALYGMELAS HHHHHHHHHHHHCC >Mature Secondary Structure PQQIELRNIALQAAQPLVHGVSLTLQRGRVLALVGGSGSGKSLTCAVALGILPAGVRQT CCCCHHHHHHHHHHHHHHHHHHEEEECCEEEEEECCCCCCCEEEEEHHHHHCCCCHHHH AGEILADGKPVSPCALRGIKIATIMQNPRSAFNPLHTMHTHARETCLALGKPADDATLTA HHHHHCCCCCCCHHHHCCEEEEEECCCCHHHHCHHHHHHHHHHHHHHHCCCCCCCHHHHH AIEAVGLENAARVLKLYPFEMSGGMLQRMMIAMAVLCESPFIIADEPTTDLDVVAQARIL HHHHHCHHHHHHHHEECCCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHH DLLESIMQKQAPGMLLVTHDMGVVARLADDVAVMSQGKIVEQGDVETLFNAPKHTVTRSL HHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHCCCCEECCCCHHHHHCCCHHHHHHHH VSAHLALYGMELAS HHHHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 7.0
TargetDB status: NA
Availability: NA
References: 11206551; 11258796 [H]