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The map label for this gene is yhgN

Identifier: 157162913

GI number: 157162913

Start: 3622107

End: 3622700

Strand: Direct

Name: yhgN

Synonym: EcHS_A3634

Alternate gene names: 157162913

Gene position: 3622107-3622700 (Clockwise)

Preceding gene: 157162903

Following gene: 157162919

Centisome position: 78.0

GC content: 50.34

Gene sequence:

>594_bases
ATGAATGAAATCATTTCTGCAGCAGTTTTATTGATCCTGATTATGGATCCGCTCGGAAACCTACCTATTTTCATGTCCGT
ACTGAAACATACTGAACCGAAAAGACGGCGGGCAATCATGGTGCGAGAGTTGCTTATTGCTCTCCTGGTGATGCTGGTGT
TCCTGTTTGCGGGTGAGAAAATTCTGGCATTTCTCAGCCTGCGAGCAGAAACCGTCTCCATTTCTGGCGGCATCATTCTG
TTTCTGATCGCCATTAAGATGATTTTCCCCAGCGCTTCAGGAAATAGCAGCGGGCTTCCTGCAGGTGAAGAGCCATTTAT
CGTGCCGTTGGCAATTCCGTTAGTCGCCGGGCCGACTATTCTCGCCACGCTGATGTTGTTGTCTCATCAGTACCCGAATC
AGATGGGGCATCTGGTGATTGCTCTGCTGCTGGCCTGGGGCGGCACCTTTGTCATCCTGCTACAGTCTTCGCTATTTTTA
CGTCTGCTGGGCGAGAAAGGGGTGAACGCACTTGAACGCCTGATGGGATTGATTCTGGTGATGATGGCAACCCAGATGTT
CCTCGACGGCATTCGAATGTGGATGAAGGGGTAA

Upstream 100 bases:

>100_bases
AAGTGAAATTAATCAATGATAGCGAAGCCATCAGTAATGCGACTTATCCTGCTTTGTTAGCACGCAGAAAGTCCGCGGCA
ATTATCAGGGAATTTGAGTT

Downstream 100 bases:

>100_bases
CGAGGAGAGTTTTTCGAAAAGAACCCGGTAGCGTCACAACTACCGGGCGAACAAACTTAACTCAACAGCTGGAACGCAAT
CATCCCAACGATGGCACCGA

Product: putative dITP- and XTP- hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 197; Mature: 197

Protein sequence:

>197_residues
MNEIISAAVLLILIMDPLGNLPIFMSVLKHTEPKRRRAIMVRELLIALLVMLVFLFAGEKILAFLSLRAETVSISGGIIL
FLIAIKMIFPSASGNSSGLPAGEEPFIVPLAIPLVAGPTILATLMLLSHQYPNQMGHLVIALLLAWGGTFVILLQSSLFL
RLLGEKGVNALERLMGLILVMMATQMFLDGIRMWMKG

Sequences:

>Translated_197_residues
MNEIISAAVLLILIMDPLGNLPIFMSVLKHTEPKRRRAIMVRELLIALLVMLVFLFAGEKILAFLSLRAETVSISGGIIL
FLIAIKMIFPSASGNSSGLPAGEEPFIVPLAIPLVAGPTILATLMLLSHQYPNQMGHLVIALLLAWGGTFVILLQSSLFL
RLLGEKGVNALERLMGLILVMMATQMFLDGIRMWMKG
>Mature_197_residues
MNEIISAAVLLILIMDPLGNLPIFMSVLKHTEPKRRRAIMVRELLIALLVMLVFLFAGEKILAFLSLRAETVSISGGIIL
FLIAIKMIFPSASGNSSGLPAGEEPFIVPLAIPLVAGPTILATLMLLSHQYPNQMGHLVIALLLAWGGTFVILLQSSLFL
RLLGEKGVNALERLMGLILVMMATQMFLDGIRMWMKG

Specific function: Unknown

COG id: COG2095

COG function: function code U; Multiple antibiotic transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0056 (marC) family

Homologues:

Organism=Escherichia coli, GI1789842, Length=197, Percent_Identity=100, Blast_Score=380, Evalue=1e-107,
Organism=Escherichia coli, GI1787494, Length=195, Percent_Identity=27.6923076923077, Blast_Score=69, Evalue=1e-13,
Organism=Escherichia coli, GI1787809, Length=200, Percent_Identity=26, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YHGN_ECO57 (P67144)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   G91163
- PIR:   H86009
- RefSeq:   NP_289979.1
- RefSeq:   NP_312306.1
- ProteinModelPortal:   P67144
- EnsemblBacteria:   EBESCT00000025178
- EnsemblBacteria:   EBESCT00000058828
- GeneID:   915864
- GeneID:   961596
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z4798
- KEGG:   ecs:ECs4279
- GeneTree:   EBGT00050000010129
- HOGENOM:   HBG731519
- OMA:   FLFAGEA
- ProtClustDB:   PRK10739
- BioCyc:   ECOL83334:ECS4279-MONOMER
- InterPro:   IPR002771
- TIGRFAMs:   TIGR00427

Pfam domain/function: PF01914 MarC

EC number: NA

Molecular weight: Translated: 21491; Mature: 21491

Theoretical pI: Translated: 10.27; Mature: 10.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1808d914)-; HASH(0x1819a6b8)-; HASH(0x179d4f90)-; HASH(0x178d8304)-; HASH(0x16bb54d8)-; HASH(0x1822b2dc)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
7.1 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
7.1 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEIISAAVLLILIMDPLGNLPIFMSVLKHTEPKRRRAIMVRELLIALLVMLVFLFAGEK
CHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHH
ILAFLSLRAETVSISGGIILFLIAIKMIFPSASGNSSGLPAGEEPFIVPLAIPLVAGPTI
HHHHHHHHHHHEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEHHHHHCCHHH
LATLMLLSHQYPNQMGHLVIALLLAWGGTFVILLQSSLFLRLLGEKGVNALERLMGLILV
HHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
MMATQMFLDGIRMWMKG
HHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MNEIISAAVLLILIMDPLGNLPIFMSVLKHTEPKRRRAIMVRELLIALLVMLVFLFAGEK
CHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHH
ILAFLSLRAETVSISGGIILFLIAIKMIFPSASGNSSGLPAGEEPFIVPLAIPLVAGPTI
HHHHHHHHHHHEECCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEHHHHHCCHHH
LATLMLLSHQYPNQMGHLVIALLLAWGGTFVILLQSSLFLRLLGEKGVNALERLMGLILV
HHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
MMATQMFLDGIRMWMKG
HHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796