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The map label for this gene is feoB

Identifier: 157162886

GI number: 157162886

Start: 3584747

End: 3587068

Strand: Direct

Name: feoB

Synonym: EcHS_A3606

Alternate gene names: 157162886

Gene position: 3584747-3587068 (Clockwise)

Preceding gene: 157162885

Following gene: 157162887

Centisome position: 77.2

GC content: 54.74

Gene sequence:

>2322_bases
ATGAAAAAATTAACCATAGGCTTAATTGGTAATCCAAATTCTGGCAAGACAACCTTATTTAACCAGCTCACTGGCGCACG
TCAGCGTGTAGGTAACTGGGCTGGCGTTACCGTCGAACGTAAAGAAGGGCAATTCTCCACCACCGATCATCAGGTCACGC
TGGTGGACCTGCCCGGCACCTATTCTCTGACCACCATCTCATCGCAGACCTCGCTCGATGAGCAAATCGCCTGTCACTAC
ATTTTGAGTGGCGACGCCGACCTGCTGATTAACGTGGTGGATGCGTCTAACCTTGAGCGTAACCTGTACCTGACGCTACA
ACTGCTGGAACTCGGCATTCCCTGCATTGTGGCACTGAACATGCTCGACATTGCCGAGAAGCAAAATATTCGTATTGAAA
TTGATGCTCTGTCGGCGCGTCTGGGCTGTCCGGTGATCCCGCTGGTTTCAACCCGTGGTCGCGGTATTGAAGCGCTCAAG
CTGGCGATTGATCGCTATAAAGCTAACGAGAATGTGGAACTGGTACATTACGCACAGCCGCTACTCAACGAAGCAGATTC
ACTGGCAAAAGTGATGCCTTCCGACATCCCGCTGAAACAACGTCGCTGGCTGGGCCTGCAAATGCTGGAAGGCGATATCT
ACAGCCGCGCCTACGCCGGTGAAGCGTCGCAGCATCTTGATGCCGCCCTCGCCCGTCTGCGTAATGAGATGGACGATCCG
GCGCTGCACATTGCCGATGCGCGTTACCAGTGCATTGCTGCCATCTGTGATGTGGTAAGCAACACCCTGACGGCAGAACC
CAGCCGTTTCACCACTGCGGTAGATAAAATCGTGCTCAACCGTTTCCTCGGTCTGCCGATTTTCCTCTTTGTGATGTACC
TGATGTTCCTGCTGGCTATCAACATCGGCGGGGCGTTACAGCCGCTGTTTGATGTCGGCTCCGTGGCGCTATTTGTGCAT
GGTATTCAATGGATTGGCTACACGCTCCACTTCCCGGACTGGCTGACTATCTTCCTCGCCCAGGGCCTGGGTGGCGGTAT
TAACACCGTGCTGCCACTGGTGCCGCAGATTGGCATGATGTACCTGTTCCTCTCCTTCCTTGAGGACTCCGGCTATATGG
CGCGTGCGGCGTTTGTGATGGACCGCCTGATGCAGGCGCTGGGCTTGCCTGGGAAATCCTTTGTGCCGCTGATCGTCGGT
TTCGGTTGTAACGTACCGTCGGTAATGGGCGCACGTACGCTTGATGCACCGCGTGAACGTCTGATGACCATCATGATGGC
ACCGTTTATGTCCTGCGGCGCGCGTCTGGCTATCTTCGCAGTATTCGCGGCTGCCTTCTTCGGGCAGAACGGTGCCCTGG
CGGTTTTCTCGCTGTATATGCTGGGTATCGTGATGGCGGTGCTGACTGGCCTGATGCTCAAGTACACCATCATGCGCGGT
GAAGCGACGCCGTTTGTCATGGAGCTGCCGGTCTACCATGTACCACACGTTAAAAGCCTGATTATCCAGACCTGGCAGCG
TCTGAAAGGCTTCGTTCTGCGTGCTGGTAAAGTGATTATCATCGTCAGCATTTTCCTGAGCGCCTTCAACAGCTTCTCGC
TGAGCGGAAAAATCGTCGATAACATCAACGACTCGGCGCTGGCTTCCGTCAGCCGGGTGATCACCCCAGTCTTCAAGCCG
ATTGGCGTGCATGAAGATAACTGGCAGGCAACGGTTGGCCTGTTTACAGGTGCAATGGCGAAAGAAGTGGTGGTGGGCAC
GCTCAACACCCTCTACACCGCAGAAAATATTCAGGACGAAGAGTTCAATCCGGCAGAATTTAACCTCGGTGAAGAGCTGT
TCAGCGCGGTAGATGAAACCTGGCAGAGCCTGAAAGACACCTTCAGCCTTAGCGTACTGATGAATCCCATTGAAGCGAGC
AAAGGCGACGGCGAAATGGGTACCGGGGCGATGGGCGTGATGGATCAGAAATTCGGTAGCGCAGCTGCCGCATACAGCTA
CCTGATTTTCGTCCTGCTGTATGTACCATGTATCTCGGTGATGGGAGCCATCGCCCGTGAATCAAGCCGTGGCTGGATGG
GCTTCTCCATCCTGTGGGGGCTGAATATCGCTTACTCACTGGCAACATTGTTCTATCAGGTCGCCAGCTACAGTCAGCAC
CCAACTTACAGCCTGGTGTGCATTCTGGCGGTAATCCTGTTTAACATCGTAGTTATCGGTCTGCTGCGCCGCGCGCGTAG
CCGGGTGGATATCGAACTGCTGGCAACCCGCAAGTCGGTAAGCAGTTGCTGCGCAGCCAGCACCACCGGTGATTGCCATT
AA

Upstream 100 bases:

>100_bases
ATTCATATCGAAACCCGTCGTGTGAGCCTGGTATTACGCAAAAAAGATCTGGCCTTATTAGAAGTGGAAGCGGTTTCCTG
TTAATACGGTGATAACAACA

Downstream 100 bases:

>100_bases
TGGCTTCACTTATTCAGGTACGTGATTTGCTGGCGTTACGGGGCCGTATGGAAGCGACCCAGATAAGCCAGACATTGAAC
ACTCCGCAGCCAATGATTAA

Product: ferrous iron transport protein B

Products: Fe (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 773; Mature: 773

Protein sequence:

>773_residues
MKKLTIGLIGNPNSGKTTLFNQLTGARQRVGNWAGVTVERKEGQFSTTDHQVTLVDLPGTYSLTTISSQTSLDEQIACHY
ILSGDADLLINVVDASNLERNLYLTLQLLELGIPCIVALNMLDIAEKQNIRIEIDALSARLGCPVIPLVSTRGRGIEALK
LAIDRYKANENVELVHYAQPLLNEADSLAKVMPSDIPLKQRRWLGLQMLEGDIYSRAYAGEASQHLDAALARLRNEMDDP
ALHIADARYQCIAAICDVVSNTLTAEPSRFTTAVDKIVLNRFLGLPIFLFVMYLMFLLAINIGGALQPLFDVGSVALFVH
GIQWIGYTLHFPDWLTIFLAQGLGGGINTVLPLVPQIGMMYLFLSFLEDSGYMARAAFVMDRLMQALGLPGKSFVPLIVG
FGCNVPSVMGARTLDAPRERLMTIMMAPFMSCGARLAIFAVFAAAFFGQNGALAVFSLYMLGIVMAVLTGLMLKYTIMRG
EATPFVMELPVYHVPHVKSLIIQTWQRLKGFVLRAGKVIIIVSIFLSAFNSFSLSGKIVDNINDSALASVSRVITPVFKP
IGVHEDNWQATVGLFTGAMAKEVVVGTLNTLYTAENIQDEEFNPAEFNLGEELFSAVDETWQSLKDTFSLSVLMNPIEAS
KGDGEMGTGAMGVMDQKFGSAAAAYSYLIFVLLYVPCISVMGAIARESSRGWMGFSILWGLNIAYSLATLFYQVASYSQH
PTYSLVCILAVILFNIVVIGLLRRARSRVDIELLATRKSVSSCCAASTTGDCH

Sequences:

>Translated_773_residues
MKKLTIGLIGNPNSGKTTLFNQLTGARQRVGNWAGVTVERKEGQFSTTDHQVTLVDLPGTYSLTTISSQTSLDEQIACHY
ILSGDADLLINVVDASNLERNLYLTLQLLELGIPCIVALNMLDIAEKQNIRIEIDALSARLGCPVIPLVSTRGRGIEALK
LAIDRYKANENVELVHYAQPLLNEADSLAKVMPSDIPLKQRRWLGLQMLEGDIYSRAYAGEASQHLDAALARLRNEMDDP
ALHIADARYQCIAAICDVVSNTLTAEPSRFTTAVDKIVLNRFLGLPIFLFVMYLMFLLAINIGGALQPLFDVGSVALFVH
GIQWIGYTLHFPDWLTIFLAQGLGGGINTVLPLVPQIGMMYLFLSFLEDSGYMARAAFVMDRLMQALGLPGKSFVPLIVG
FGCNVPSVMGARTLDAPRERLMTIMMAPFMSCGARLAIFAVFAAAFFGQNGALAVFSLYMLGIVMAVLTGLMLKYTIMRG
EATPFVMELPVYHVPHVKSLIIQTWQRLKGFVLRAGKVIIIVSIFLSAFNSFSLSGKIVDNINDSALASVSRVITPVFKP
IGVHEDNWQATVGLFTGAMAKEVVVGTLNTLYTAENIQDEEFNPAEFNLGEELFSAVDETWQSLKDTFSLSVLMNPIEAS
KGDGEMGTGAMGVMDQKFGSAAAAYSYLIFVLLYVPCISVMGAIARESSRGWMGFSILWGLNIAYSLATLFYQVASYSQH
PTYSLVCILAVILFNIVVIGLLRRARSRVDIELLATRKSVSSCCAASTTGDCH
>Mature_773_residues
MKKLTIGLIGNPNSGKTTLFNQLTGARQRVGNWAGVTVERKEGQFSTTDHQVTLVDLPGTYSLTTISSQTSLDEQIACHY
ILSGDADLLINVVDASNLERNLYLTLQLLELGIPCIVALNMLDIAEKQNIRIEIDALSARLGCPVIPLVSTRGRGIEALK
LAIDRYKANENVELVHYAQPLLNEADSLAKVMPSDIPLKQRRWLGLQMLEGDIYSRAYAGEASQHLDAALARLRNEMDDP
ALHIADARYQCIAAICDVVSNTLTAEPSRFTTAVDKIVLNRFLGLPIFLFVMYLMFLLAINIGGALQPLFDVGSVALFVH
GIQWIGYTLHFPDWLTIFLAQGLGGGINTVLPLVPQIGMMYLFLSFLEDSGYMARAAFVMDRLMQALGLPGKSFVPLIVG
FGCNVPSVMGARTLDAPRERLMTIMMAPFMSCGARLAIFAVFAAAFFGQNGALAVFSLYMLGIVMAVLTGLMLKYTIMRG
EATPFVMELPVYHVPHVKSLIIQTWQRLKGFVLRAGKVIIIVSIFLSAFNSFSLSGKIVDNINDSALASVSRVITPVFKP
IGVHEDNWQATVGLFTGAMAKEVVVGTLNTLYTAENIQDEEFNPAEFNLGEELFSAVDETWQSLKDTFSLSVLMNPIEAS
KGDGEMGTGAMGVMDQKFGSAAAAYSYLIFVLLYVPCISVMGAIARESSRGWMGFSILWGLNIAYSLATLFYQVASYSQH
PTYSLVCILAVILFNIVVIGLLRRARSRVDIELLATRKSVSSCCAASTTGDCH

Specific function: GTP-driven Fe(2+) uptake system

COG id: COG0370

COG function: function code P; Fe2+ transport system protein B

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the feoB (TC 9.A.8) family

Homologues:

Organism=Escherichia coli, GI1789813, Length=773, Percent_Identity=99.7412677878396, Blast_Score=1583, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FEOB_ECO57 (Q8XED4)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   B86006
- PIR:   C91160
- RefSeq:   NP_289949.1
- RefSeq:   NP_312278.1
- ProteinModelPortal:   Q8XED4
- SMR:   Q8XED4
- EnsemblBacteria:   EBESCT00000025259
- EnsemblBacteria:   EBESCT00000056422
- GeneID:   915892
- GeneID:   957596
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z4764
- KEGG:   ecs:ECs4251
- GeneTree:   EBGT00050000011486
- HOGENOM:   HBG731320
- OMA:   FPESGQN
- ProtClustDB:   PRK09554
- BioCyc:   ECOL83334:ECS4251-MONOMER
- InterPro:   IPR003373
- InterPro:   IPR011640
- InterPro:   IPR011619
- InterPro:   IPR011642
- InterPro:   IPR005225
- TIGRFAMs:   TIGR00437
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF07664 FeoB_C; PF02421 FeoB_N; PF07670 Gate

EC number: NA

Molecular weight: Translated: 84445; Mature: 84445

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x11664058)-; HASH(0x17d2e2ac)-; HASH(0x173f30ac)-; HASH(0x17e70ef0)-; HASH(0x17c94f78)-; HASH(0x17d98288)-; HASH(0x17c6fac4)-; HASH(0x17837144)-; HASH(0x1807c924)-; HASH(0x178910b8)-; HASH(0x17dff5fc)-; HASH(0x17e742a0)-; HASH(0x1300cb0c)-;

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKLTIGLIGNPNSGKTTLFNQLTGARQRVGNWAGVTVERKEGQFSTTDHQVTLVDLPGT
CCEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCEEEEEECCCC
YSLTTISSQTSLDEQIACHYILSGDADLLINVVDASNLERNLYLTLQLLELGIPCIVALN
EEEEEECCCCCCCHHHHEEEEECCCCEEEEEEECCCCCCCCCEEEEEHHHHCCHHHHHHH
MLDIAEKQNIRIEIDALSARLGCPVIPLVSTRGRGIEALKLAIDRYKANENVELVHYAQP
HHHHHCCCCCEEEEEEEHHHCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCEEEEEHHHH
LLNEADSLAKVMPSDIPLKQRRWLGLQMLEGDIYSRAYAGEASQHLDAALARLRNEMDDP
HHHHHHHHHHHCCCCCCHHHHHHCCHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCC
ALHIADARYQCIAAICDVVSNTLTAEPSRFTTAVDKIVLNRFLGLPIFLFVMYLMFLLAI
CEEEHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NIGGALQPLFDVGSVALFVHGIQWIGYTLHFPDWLTIFLAQGLGGGINTVLPLVPQIGMM
CCCCHHHHHHHHHHHHHHHHHHHHHEEEEECHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
YLFLSFLEDSGYMARAAFVMDRLMQALGLPGKSFVPLIVGFGCNVPSVMGARTLDAPRER
HHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHEECCCCCCHHHCCCCCCHHHHH
LMTIMMAPFMSCGARLAIFAVFAAAFFGQNGALAVFSLYMLGIVMAVLTGLMLKYTIMRG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EATPFVMELPVYHVPHVKSLIIQTWQRLKGFVLRAGKVIIIVSIFLSAFNSFSLSGKIVD
CCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEECC
NINDSALASVSRVITPVFKPIGVHEDNWQATVGLFTGAMAKEVVVGTLNTLYTAENIQDE
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
EFNPAEFNLGEELFSAVDETWQSLKDTFSLSVLMNPIEASKGDGEMGTGAMGVMDQKFGS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCHHHHHHHHCH
AAAAYSYLIFVLLYVPCISVMGAIARESSRGWMGFSILWGLNIAYSLATLFYQVASYSQH
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCC
PTYSLVCILAVILFNIVVIGLLRRARSRVDIELLATRKSVSSCCAASTTGDCH
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEHHHHHHHHHHCCCCCCCCH
>Mature Secondary Structure
MKKLTIGLIGNPNSGKTTLFNQLTGARQRVGNWAGVTVERKEGQFSTTDHQVTLVDLPGT
CCEEEEEEEECCCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCEEEEEECCCC
YSLTTISSQTSLDEQIACHYILSGDADLLINVVDASNLERNLYLTLQLLELGIPCIVALN
EEEEEECCCCCCCHHHHEEEEECCCCEEEEEEECCCCCCCCCEEEEEHHHHCCHHHHHHH
MLDIAEKQNIRIEIDALSARLGCPVIPLVSTRGRGIEALKLAIDRYKANENVELVHYAQP
HHHHHCCCCCEEEEEEEHHHCCCCCEEEECCCCCCHHHHHHHHHHHCCCCCEEEEEHHHH
LLNEADSLAKVMPSDIPLKQRRWLGLQMLEGDIYSRAYAGEASQHLDAALARLRNEMDDP
HHHHHHHHHHHCCCCCCHHHHHHCCHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCC
ALHIADARYQCIAAICDVVSNTLTAEPSRFTTAVDKIVLNRFLGLPIFLFVMYLMFLLAI
CEEEHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NIGGALQPLFDVGSVALFVHGIQWIGYTLHFPDWLTIFLAQGLGGGINTVLPLVPQIGMM
CCCCHHHHHHHHHHHHHHHHHHHHHEEEEECHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
YLFLSFLEDSGYMARAAFVMDRLMQALGLPGKSFVPLIVGFGCNVPSVMGARTLDAPRER
HHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHEECCCCCCHHHCCCCCCHHHHH
LMTIMMAPFMSCGARLAIFAVFAAAFFGQNGALAVFSLYMLGIVMAVLTGLMLKYTIMRG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
EATPFVMELPVYHVPHVKSLIIQTWQRLKGFVLRAGKVIIIVSIFLSAFNSFSLSGKIVD
CCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEECC
NINDSALASVSRVITPVFKPIGVHEDNWQATVGLFTGAMAKEVVVGTLNTLYTAENIQDE
CCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
EFNPAEFNLGEELFSAVDETWQSLKDTFSLSVLMNPIEASKGDGEMGTGAMGVMDQKFGS
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCCCCHHHHHHHHCH
AAAAYSYLIFVLLYVPCISVMGAIARESSRGWMGFSILWGLNIAYSLATLFYQVASYSQH
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCC
PTYSLVCILAVILFNIVVIGLLRRARSRVDIELLATRKSVSSCCAASTTGDCH
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEHHHHHHHHHHCCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Fe (II) [Periplasm] [C]

Specific reaction: Fe (II) [Periplasm] = Fe (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796