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The map label for this gene is yheT [H]

Identifier: 157162830

GI number: 157162830

Start: 3527545

End: 3528567

Strand: Direct

Name: yheT [H]

Synonym: EcHS_A3550

Alternate gene names: 157162830

Gene position: 3527545-3528567 (Clockwise)

Preceding gene: 157162829

Following gene: 157162831

Centisome position: 75.97

GC content: 54.35

Gene sequence:

>1023_bases
ATGGCGCAGATAACGACGACCGATGCCAATGAATTCAGCAGCAGTGCTGAATTCACCCCTATGCGCGGCTTTAGCAATTG
TCATCTGCAAACCATGCTGCCGCGTCTGTTTCGTCGCAAGGTGAAATTCACCCCGTACTGGCAGCGGCTGGAGTTGCCCG
ACGGCGATTTTGTCGATCTCGCGTGGAGTGAAGCCCCAGCACAGGCGCGGCATAAACCGCGTTTAGTGGTATTTCACGGG
CTGGAAGGCAGTCTCAATAGCCCTTACGCCCACGGTCTGGTTGAGGCGGCGCAAAAGCGCGGCTGGCTGGGCGTGGTGAT
GCATTTTCGCGGATGCAGCGGTGAACCAAACCGTATGCACCGCATTTACCATTCGGGCGAAACCGAAGACGCCAGTTGGT
TTTTACGCTGGCTGCAACGCGAATTTGGTCATGCGCCAACGGCTGCCGTCGGCTATTCGCTCGGCGGTAATATGCTGGCC
TGTTTGCTGGCAAAGGAAGGCAATGATCTCCCGGTTGATGCGGCGGTGATTGTCTCTGCGCCGTTTATGCTGGAAGCCTG
TAGCTATCATATGGAAAAGGGCTTTTCCCGCGTTTATCAGCGTTACTTGCTGAACCTGTTAAAAGCCAATGCCGCGCGCA
AGCTGGCAGCCTACCCCGGAACGCTGCCGATTAATCTCGCGCAGTTAAAATCGGTACGTCGCATCCGTGAATTTGACGAT
CTAATCACCGCCAGAATTCACGGCTACGCCGACGCTATCGACTATTATCGTCAGTGTAGCGCCATGCCGATGCTGAACCG
GATCGCCAAACCGACGCTGATTATTCACGCCAAAGACGATCCGTTTATGGATCATCAGGTGATCCCGAAACCGGAAAGTC
TCCCCCCGCAGGTGGAGTATCAACTGACTGAACATGGCGGTCATGTTGGCTTTATTGGCGGTACATTACTTCATCCGCAA
ATGTGGCTGGAGTCACGCATTCCTGACTGGTTAACAACGTATCTGGAGGCGAAATCATGTTGA

Upstream 100 bases:

>100_bases
AGCAAGCCAGCGCCAAATCCGGCCTGGAAGAGTGCGAAATGGCGTGGCTGGAAGCCCAGGAGCAGCTTGAGCAGATGTTG
CTGGAAGGCCAAAGCAACTG

Downstream 100 bases:

>100_bases
TTCCGTGGCAAGACCTCTCCCCCGAAACGCTGGAAAATTTAATTGAAAGCTTTGTGTTACGTGAAGGCACCGATTATGGT
GAACATGAGCGTACACTTGA

Product: putative hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MAQITTTDANEFSSSAEFTPMRGFSNCHLQTMLPRLFRRKVKFTPYWQRLELPDGDFVDLAWSEAPAQARHKPRLVVFHG
LEGSLNSPYAHGLVEAAQKRGWLGVVMHFRGCSGEPNRMHRIYHSGETEDASWFLRWLQREFGHAPTAAVGYSLGGNMLA
CLLAKEGNDLPVDAAVIVSAPFMLEACSYHMEKGFSRVYQRYLLNLLKANAARKLAAYPGTLPINLAQLKSVRRIREFDD
LITARIHGYADAIDYYRQCSAMPMLNRIAKPTLIIHAKDDPFMDHQVIPKPESLPPQVEYQLTEHGGHVGFIGGTLLHPQ
MWLESRIPDWLTTYLEAKSC

Sequences:

>Translated_340_residues
MAQITTTDANEFSSSAEFTPMRGFSNCHLQTMLPRLFRRKVKFTPYWQRLELPDGDFVDLAWSEAPAQARHKPRLVVFHG
LEGSLNSPYAHGLVEAAQKRGWLGVVMHFRGCSGEPNRMHRIYHSGETEDASWFLRWLQREFGHAPTAAVGYSLGGNMLA
CLLAKEGNDLPVDAAVIVSAPFMLEACSYHMEKGFSRVYQRYLLNLLKANAARKLAAYPGTLPINLAQLKSVRRIREFDD
LITARIHGYADAIDYYRQCSAMPMLNRIAKPTLIIHAKDDPFMDHQVIPKPESLPPQVEYQLTEHGGHVGFIGGTLLHPQ
MWLESRIPDWLTTYLEAKSC
>Mature_339_residues
AQITTTDANEFSSSAEFTPMRGFSNCHLQTMLPRLFRRKVKFTPYWQRLELPDGDFVDLAWSEAPAQARHKPRLVVFHGL
EGSLNSPYAHGLVEAAQKRGWLGVVMHFRGCSGEPNRMHRIYHSGETEDASWFLRWLQREFGHAPTAAVGYSLGGNMLAC
LLAKEGNDLPVDAAVIVSAPFMLEACSYHMEKGFSRVYQRYLLNLLKANAARKLAAYPGTLPINLAQLKSVRRIREFDDL
ITARIHGYADAIDYYRQCSAMPMLNRIAKPTLIIHAKDDPFMDHQVIPKPESLPPQVEYQLTEHGGHVGFIGGTLLHPQM
WLESRIPDWLTTYLEAKSC

Specific function: Unknown

COG id: COG0429

COG function: function code R; Predicted hydrolase of the alpha/beta-hydrolase fold

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. AB hydrolase 4 family [H]

Homologues:

Organism=Homo sapiens, GI23397663, Length=292, Percent_Identity=27.7397260273973, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI194578891, Length=285, Percent_Identity=29.8245614035088, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI23397659, Length=326, Percent_Identity=25.7668711656442, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI23397661, Length=326, Percent_Identity=25.7668711656442, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI269315865, Length=314, Percent_Identity=26.7515923566879, Blast_Score=69, Evalue=4e-12,
Organism=Escherichia coli, GI1789752, Length=340, Percent_Identity=98.8235294117647, Blast_Score=706, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17566110, Length=306, Percent_Identity=25.8169934640523, Blast_Score=104, Evalue=8e-23,
Organism=Caenorhabditis elegans, GI71985405, Length=305, Percent_Identity=23.6065573770492, Blast_Score=97, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6325162, Length=290, Percent_Identity=31.3793103448276, Blast_Score=112, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6319655, Length=290, Percent_Identity=26.8965517241379, Blast_Score=107, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6323866, Length=246, Percent_Identity=30.0813008130081, Blast_Score=105, Evalue=9e-24,
Organism=Drosophila melanogaster, GI24652003, Length=295, Percent_Identity=30.8474576271186, Blast_Score=111, Evalue=5e-25,
Organism=Drosophila melanogaster, GI281398151, Length=295, Percent_Identity=30.8474576271186, Blast_Score=111, Evalue=6e-25,
Organism=Drosophila melanogaster, GI24581365, Length=322, Percent_Identity=22.9813664596273, Blast_Score=83, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012020
- InterPro:   IPR000073
- InterPro:   IPR000952 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: NA

Molecular weight: Translated: 38469; Mature: 38337

Theoretical pI: Translated: 8.16; Mature: 8.16

Prosite motif: PS01133 UPF0017

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQITTTDANEFSSSAEFTPMRGFSNCHLQTMLPRLFRRKVKFTPYWQRLELPDGDFVDL
CCEEECCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHEEECCCCCEEEE
AWSEAPAQARHKPRLVVFHGLEGSLNSPYAHGLVEAAQKRGWLGVVMHFRGCSGEPNRMH
ECCCCCHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHH
RIYHSGETEDASWFLRWLQREFGHAPTAAVGYSLGGNMLACLLAKEGNDLPVDAAVIVSA
HHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHCCCCCEEEEEEECCCCCCCCCHHHHHCC
PFMLEACSYHMEKGFSRVYQRYLLNLLKANAARKLAAYPGTLPINLAQLKSVRRIREFDD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
LITARIHGYADAIDYYRQCSAMPMLNRIAKPTLIIHAKDDPFMDHQVIPKPESLPPQVEY
HHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEE
QLTEHGGHVGFIGGTLLHPQMWLESRIPDWLTTYLEAKSC
EECCCCCEEEEECCHHHCHHHHHHHCCHHHHHHHHHHCCC
>Mature Secondary Structure 
AQITTTDANEFSSSAEFTPMRGFSNCHLQTMLPRLFRRKVKFTPYWQRLELPDGDFVDL
CEEECCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHEEECCCCCEEEE
AWSEAPAQARHKPRLVVFHGLEGSLNSPYAHGLVEAAQKRGWLGVVMHFRGCSGEPNRMH
ECCCCCHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHCCCEEEEEEECCCCCCCHHHH
RIYHSGETEDASWFLRWLQREFGHAPTAAVGYSLGGNMLACLLAKEGNDLPVDAAVIVSA
HHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHCCCCCEEEEEEECCCCCCCCCHHHHHCC
PFMLEACSYHMEKGFSRVYQRYLLNLLKANAARKLAAYPGTLPINLAQLKSVRRIREFDD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
LITARIHGYADAIDYYRQCSAMPMLNRIAKPTLIIHAKDDPFMDHQVIPKPESLPPQVEY
HHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCEEE
QLTEHGGHVGFIGGTLLHPQMWLESRIPDWLTTYLEAKSC
EECCCCCEEEEECCHHHCHHHHHHHCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]