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The map label for this gene is dprA

Identifier: 157162759

GI number: 157162759

Start: 3476779

End: 3477903

Strand: Reverse

Name: dprA

Synonym: EcHS_A3479

Alternate gene names: 157162759

Gene position: 3477903-3476779 (Counterclockwise)

Preceding gene: 157162765

Following gene: 157162758

Centisome position: 74.9

GC content: 50.93

Gene sequence:

>1125_bases
ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGTATCAGCAGCTTGTACGGCGATGATATGGTCCGTATCGCTCACTG
GGTGGCAAAACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT
CATTTCCACGAAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATTCCTGCGGACAGCGAA
TTTTATCCTCCTCAACTTCTGGCGACGACAGATTACCCCGGCGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC
ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG
CGACGCGTGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTAGCGCATAAAGCAGCCTTACAGGTAAAT
GGCGTCAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCCCGCCGTCATGCCCGACTGGCTGCCAGTCTGCT
TGAACAGGGGGGCGCTCTCGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCCCACGAAGAAATCGCA
TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGTAGTGGTTCGCTGGTGACAGCACGTTGTGCG
CTTGAGCAGGGGCGAGAAGTTTTTGCCTTGCCAGGTCCAATAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA
ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC
CTGAAAATTCATTTTATTCACCAGATCAGCAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG
GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT
AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG
TTTGA

Upstream 100 bases:

>100_bases
AAAGATTATTTCTTCTATTCTAGACAAATCCCCCTCTGATTGACAGCATCACTGACCAATCGCAAAGATTGCTAAGGCTG
CTTATGGCAGGGAGATAAGG

Downstream 100 bases:

>100_bases
AACCTATATTCACACAGAAGCTGAGTTGCGTGTGGATCAAGACAAACTTGAACAGGATCTTACCGACGCAGGTTTTGAGC
GAGAAGATATCTACAATGCC

Product: DNA protecting protein DprA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 374; Mature: 374

Protein sequence:

>374_residues
MVDTEIWLRLMSISSLYGDDMVRIAHWVAKQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE
FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN
GVSIAVLGNGLNTIHPRRHARLAASLLEQGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA
LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQQDVALPFPELLANVGDE
VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Sequences:

>Translated_374_residues
MVDTEIWLRLMSISSLYGDDMVRIAHWVAKQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE
FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN
GVSIAVLGNGLNTIHPRRHARLAASLLEQGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA
LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQQDVALPFPELLANVGDE
VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV
>Mature_374_residues
MVDTEIWLRLMSISSLYGDDMVRIAHWVAKQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE
FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN
GVSIAVLGNGLNTIHPRRHARLAASLLEQGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA
LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQQDVALPFPELLANVGDE
VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Specific function: Unknown

COG id: COG0758

COG function: function code LU; Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the smf family

Homologues:

Organism=Escherichia coli, GI48994932, Length=374, Percent_Identity=100, Blast_Score=757, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SMF_ECOLI (P30852)

Other databases:

- EMBL:   X65946
- EMBL:   X77091
- EMBL:   X77800
- EMBL:   U18997
- EMBL:   U18997
- EMBL:   U00096
- EMBL:   AP009048
- RefSeq:   AP_004505.1
- RefSeq:   YP_026211.1
- ProteinModelPortal:   P30852
- SMR:   P30852
- STRING:   P30852
- EnsemblBacteria:   EBESCT00000000628
- EnsemblBacteria:   EBESCT00000015101
- GeneID:   2847708
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW5708
- KEGG:   eco:b4473
- EchoBASE:   EB1561
- EcoGene:   EG11604
- eggNOG:   COG0758
- GeneTree:   EBGT00050000011833
- HOGENOM:   HBG758551
- OMA:   VMMQLLE
- ProtClustDB:   PRK10736
- BioCyc:   EcoCyc:EG11604-MONOMER
- Genevestigator:   P30852
- InterPro:   IPR003488
- TIGRFAMs:   TIGR00732

Pfam domain/function: PF02481 DNA_processg_A

EC number: NA

Molecular weight: Translated: 40955; Mature: 40955

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDTEIWLRLMSISSLYGDDMVRIAHWVAKQSHIDAVVLQQTGLTLRQAQRFLSFPRKSI
CCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHCCHHHH
ESSLCWLEQPNHHLIPADSEFYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSW
HHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCEEEECCCHHHHHHEEEEEECCHHHHH
YGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVNGVSIAVLGNGLNTIHPRRHA
HHHHHHHHHHHHHHHCCEEEHHHHHHHHHHHHHHHEEEECCEEEEEEECCCCCCCCHHHH
RLAASLLEQGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA
HHHHHHHHCCCCEEHHCCCCCCCCCCCCCHHHHHHHHHHCCHHEEEHHHCCCCEEEEHHH
LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYS
HHCCCEEEECCCCCCCCCCCCCCEEEECCCEEEECHHHHHHHHHHCEEECCCCCCCCCCC
PDQQDVALPFPELLANVGDEVTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVR
CCCCCCCCCHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHH
LRRACHVRRTNVFV
HHHHHHHHHHCCCC
>Mature Secondary Structure
MVDTEIWLRLMSISSLYGDDMVRIAHWVAKQSHIDAVVLQQTGLTLRQAQRFLSFPRKSI
CCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHCCHHHH
ESSLCWLEQPNHHLIPADSEFYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSW
HHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCCEEEECCCHHHHHHEEEEEECCHHHHH
YGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVNGVSIAVLGNGLNTIHPRRHA
HHHHHHHHHHHHHHHCCEEEHHHHHHHHHHHHHHHEEEECCEEEEEEECCCCCCCCHHHH
RLAASLLEQGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA
HHHHHHHHCCCCEEHHCCCCCCCCCCCCCHHHHHHHHHHCCHHEEEHHHCCCCEEEEHHH
LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYS
HHCCCEEEECCCCCCCCCCCCCCEEEECCCEEEECHHHHHHHHHHCEEECCCCCCCCCCC
PDQQDVALPFPELLANVGDEVTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVR
CCCCCCCCCHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHH
LRRACHVRRTNVFV
HHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8432722; 8112305; 9278503